NO320704B1 - Nye 8A- og 9A-15-ringlaktamer, anvendelse og fremgangsmate for fremstilling derav, samt farmasoytisk preparat. - Google Patents

Nye 8A- og 9A-15-ringlaktamer, anvendelse og fremgangsmate for fremstilling derav, samt farmasoytisk preparat. Download PDF

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Publication number
NO320704B1
NO320704B1 NO20015068A NO20015068A NO320704B1 NO 320704 B1 NO320704 B1 NO 320704B1 NO 20015068 A NO20015068 A NO 20015068A NO 20015068 A NO20015068 A NO 20015068A NO 320704 B1 NO320704 B1 NO 320704B1
Authority
NO
Norway
Prior art keywords
group
alkyl
hydrogen
formula
amino
Prior art date
Application number
NO20015068A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015068D0 (no
NO20015068L (no
Inventor
Sulejman Alihodzic
Stjepan Mutak
Gorjana Lazarevski
Gabrijela Kobrehel
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Publication of NO20015068D0 publication Critical patent/NO20015068D0/no
Publication of NO20015068L publication Critical patent/NO20015068L/no
Publication of NO320704B1 publication Critical patent/NO320704B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
NO20015068A 1999-04-20 2001-10-18 Nye 8A- og 9A-15-ringlaktamer, anvendelse og fremgangsmate for fremstilling derav, samt farmasoytisk preparat. NO320704B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990116A HRP990116B1 (en) 1999-04-20 1999-04-20 NOVEL 8a AND 9a- 15-MEMBERED LACTAMES
PCT/HR2000/000009 WO2000063223A1 (en) 1999-04-20 2000-04-19 Novel 8a- and 9a-15-membered lactams

Publications (3)

Publication Number Publication Date
NO20015068D0 NO20015068D0 (no) 2001-10-18
NO20015068L NO20015068L (no) 2001-12-13
NO320704B1 true NO320704B1 (no) 2006-01-16

Family

ID=10946907

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015068A NO320704B1 (no) 1999-04-20 2001-10-18 Nye 8A- og 9A-15-ringlaktamer, anvendelse og fremgangsmate for fremstilling derav, samt farmasoytisk preparat.

Country Status (33)

Country Link
US (1) US6593360B1 (tr)
EP (1) EP1181298B1 (tr)
JP (1) JP2002542254A (tr)
KR (1) KR20020007379A (tr)
CN (1) CN1246327C (tr)
AR (1) AR028823A1 (tr)
AT (1) ATE333461T1 (tr)
AU (1) AU772272B2 (tr)
BG (1) BG65281B1 (tr)
BR (1) BR0009943A (tr)
CA (1) CA2370273A1 (tr)
CZ (1) CZ20013730A3 (tr)
DE (1) DE60029439T2 (tr)
DK (1) DK1181298T3 (tr)
EA (1) EA003928B1 (tr)
EE (1) EE04553B1 (tr)
ES (1) ES2267519T3 (tr)
GE (1) GEP20032929B (tr)
HK (1) HK1049842B (tr)
HR (1) HRP990116B1 (tr)
HU (1) HUP0200868A3 (tr)
IL (1) IL145990A0 (tr)
IS (1) IS6110A (tr)
MX (1) MXPA01010627A (tr)
NO (1) NO320704B1 (tr)
NZ (1) NZ515279A (tr)
PL (1) PL351523A1 (tr)
PT (1) PT1181298E (tr)
SK (1) SK14942001A3 (tr)
TR (1) TR200103019T2 (tr)
UA (1) UA72246C2 (tr)
WO (1) WO2000063223A1 (tr)
ZA (1) ZA200108481B (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
US7435805B2 (en) * 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
MX377459B (es) 2013-04-04 2025-03-10 Harvard College Macrolidos y metodos para su preparacion y uso.
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
CN107530365A (zh) 2015-03-25 2018-01-02 哈佛大学的校长及成员们 具有修饰的脱氧糖胺糖的大环内酯及其用途
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
AU2340797A (en) * 1996-05-07 1997-11-26 Abbott Laboratories 6-o-substituted erythromycins and method for making them
WO1999019331A1 (en) * 1997-10-16 1999-04-22 Merck & Co., Inc. 8a-azalides, compositions containing such compounds and methods of treatment
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides

Also Published As

Publication number Publication date
HRP990116A2 (en) 2001-10-31
EA200101103A1 (ru) 2002-04-25
EP1181298B1 (en) 2006-07-19
UA72246C2 (uk) 2005-02-15
HUP0200868A3 (en) 2003-03-28
AU4134700A (en) 2000-11-02
IL145990A0 (en) 2002-07-25
TR200103019T2 (tr) 2002-01-21
EA003928B1 (ru) 2003-10-30
KR20020007379A (ko) 2002-01-26
DE60029439T2 (de) 2007-02-01
NO20015068D0 (no) 2001-10-18
DK1181298T3 (da) 2006-11-13
PL351523A1 (en) 2003-05-05
BG65281B1 (bg) 2007-11-30
EE04553B1 (et) 2005-10-17
BR0009943A (pt) 2002-01-08
MXPA01010627A (es) 2002-06-04
CN1362964A (zh) 2002-08-07
PT1181298E (pt) 2006-11-30
CN1246327C (zh) 2006-03-22
EE200100544A (et) 2003-02-17
NZ515279A (en) 2003-04-29
EP1181298A1 (en) 2002-02-27
HRP990116B1 (en) 2007-10-31
ATE333461T1 (de) 2006-08-15
WO2000063223A1 (en) 2000-10-26
JP2002542254A (ja) 2002-12-10
SK14942001A3 (sk) 2002-08-06
CA2370273A1 (en) 2000-10-26
US6593360B1 (en) 2003-07-15
AR028823A1 (es) 2003-05-28
DE60029439D1 (de) 2006-08-31
NO20015068L (no) 2001-12-13
BG106117A (en) 2002-07-31
HK1049842A1 (en) 2003-05-30
GEP20032929B (en) 2003-03-25
AU772272B2 (en) 2004-04-22
ES2267519T3 (es) 2007-03-16
HUP0200868A2 (hu) 2002-07-29
ZA200108481B (en) 2003-03-26
HK1049842B (zh) 2006-09-22
CZ20013730A3 (cs) 2002-04-17
IS6110A (is) 2001-10-16

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