EE04553B1 - 15-llilised 8a- ja 9a-laktaamid ning nende valmistamismeetod - Google Patents

15-llilised 8a- ja 9a-laktaamid ning nende valmistamismeetod

Info

Publication number
EE04553B1
EE04553B1 EEP200100544A EEP200100544A EE04553B1 EE 04553 B1 EE04553 B1 EE 04553B1 EE P200100544 A EEP200100544 A EE P200100544A EE P200100544 A EEP200100544 A EE P200100544A EE 04553 B1 EE04553 B1 EE 04553B1
Authority
EE
Estonia
Prior art keywords
lactated
lactams
preparation
Prior art date
Application number
EEP200100544A
Other languages
English (en)
Inventor
Lazarevski Gorjana
Alihodzic Sulejman
Kobrehel Gabrijela
Mutak Stjepan
Original Assignee
PLIVA, farmaceutska industrija, dionicko dru�tvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PLIVA, farmaceutska industrija, dionicko dru�tvo filed Critical PLIVA, farmaceutska industrija, dionicko dru�tvo
Publication of EE200100544A publication Critical patent/EE200100544A/et
Publication of EE04553B1 publication Critical patent/EE04553B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
EEP200100544A 1999-04-20 2000-04-19 15-llilised 8a- ja 9a-laktaamid ning nende valmistamismeetod EE04553B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990116A HRP990116B1 (en) 1999-04-20 1999-04-20 NOVEL 8a AND 9a- 15-MEMBERED LACTAMES
PCT/HR2000/000009 WO2000063223A1 (en) 1999-04-20 2000-04-19 Novel 8a- and 9a-15-membered lactams

Publications (2)

Publication Number Publication Date
EE200100544A EE200100544A (et) 2003-02-17
EE04553B1 true EE04553B1 (et) 2005-10-17

Family

ID=10946907

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100544A EE04553B1 (et) 1999-04-20 2000-04-19 15-llilised 8a- ja 9a-laktaamid ning nende valmistamismeetod

Country Status (33)

Country Link
US (1) US6593360B1 (et)
EP (1) EP1181298B1 (et)
JP (1) JP2002542254A (et)
KR (1) KR20020007379A (et)
CN (1) CN1246327C (et)
AR (1) AR028823A1 (et)
AT (1) ATE333461T1 (et)
AU (1) AU772272B2 (et)
BG (1) BG65281B1 (et)
BR (1) BR0009943A (et)
CA (1) CA2370273A1 (et)
CZ (1) CZ20013730A3 (et)
DE (1) DE60029439T2 (et)
DK (1) DK1181298T3 (et)
EA (1) EA003928B1 (et)
EE (1) EE04553B1 (et)
ES (1) ES2267519T3 (et)
GE (1) GEP20032929B (et)
HK (1) HK1049842B (et)
HR (1) HRP990116B1 (et)
HU (1) HUP0200868A3 (et)
IL (1) IL145990A0 (et)
IS (1) IS6110A (et)
MX (1) MXPA01010627A (et)
NO (1) NO320704B1 (et)
NZ (1) NZ515279A (et)
PL (1) PL351523A1 (et)
PT (1) PT1181298E (et)
SK (1) SK14942001A3 (et)
TR (1) TR200103019T2 (et)
UA (1) UA72246C2 (et)
WO (1) WO2000063223A1 (et)
ZA (1) ZA200108481B (et)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
US7435805B2 (en) * 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
US7547679B2 (en) 2005-05-10 2009-06-16 Glaxosmithkline Istrazivacki Center Zagreb D.O.O Ether linked macrolides useful for the treatment of microbial infections
CN105246334A (zh) 2013-04-04 2016-01-13 哈佛大学的校长及成员们 大环内酯及其制备和使用方法
US10633407B2 (en) 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
JP2018509452A (ja) 2015-03-25 2018-04-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 修飾デソサミン糖をもつマクロライドおよびその使用
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
AU2340797A (en) * 1996-05-07 1997-11-26 Abbott Laboratories 6-o-substituted erythromycins and method for making them
AU1082599A (en) * 1997-10-16 1999-05-03 Merck & Co., Inc. 8a-azalides, compositions containing such compounds and methods of treatment
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides

Also Published As

Publication number Publication date
DK1181298T3 (da) 2006-11-13
CN1362964A (zh) 2002-08-07
CA2370273A1 (en) 2000-10-26
GEP20032929B (en) 2003-03-25
JP2002542254A (ja) 2002-12-10
HUP0200868A3 (en) 2003-03-28
NO20015068L (no) 2001-12-13
EP1181298A1 (en) 2002-02-27
ATE333461T1 (de) 2006-08-15
HRP990116A2 (en) 2001-10-31
AU772272B2 (en) 2004-04-22
EA200101103A1 (ru) 2002-04-25
NO320704B1 (no) 2006-01-16
ZA200108481B (en) 2003-03-26
PT1181298E (pt) 2006-11-30
BG65281B1 (bg) 2007-11-30
UA72246C2 (uk) 2005-02-15
EA003928B1 (ru) 2003-10-30
HK1049842B (zh) 2006-09-22
US6593360B1 (en) 2003-07-15
AU4134700A (en) 2000-11-02
DE60029439D1 (de) 2006-08-31
NO20015068D0 (no) 2001-10-18
EP1181298B1 (en) 2006-07-19
TR200103019T2 (tr) 2002-01-21
NZ515279A (en) 2003-04-29
AR028823A1 (es) 2003-05-28
PL351523A1 (en) 2003-05-05
MXPA01010627A (es) 2002-06-04
CZ20013730A3 (cs) 2002-04-17
BR0009943A (pt) 2002-01-08
IS6110A (is) 2001-10-16
WO2000063223A1 (en) 2000-10-26
DE60029439T2 (de) 2007-02-01
EE200100544A (et) 2003-02-17
BG106117A (en) 2002-07-31
CN1246327C (zh) 2006-03-22
HRP990116B1 (en) 2007-10-31
HUP0200868A2 (hu) 2002-07-29
ES2267519T3 (es) 2007-03-16
IL145990A0 (en) 2002-07-25
HK1049842A1 (en) 2003-05-30
SK14942001A3 (sk) 2002-08-06
KR20020007379A (ko) 2002-01-26

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090419