NO318783B1 - Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. - Google Patents
Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. Download PDFInfo
- Publication number
- NO318783B1 NO318783B1 NO19975729A NO975729A NO318783B1 NO 318783 B1 NO318783 B1 NO 318783B1 NO 19975729 A NO19975729 A NO 19975729A NO 975729 A NO975729 A NO 975729A NO 318783 B1 NO318783 B1 NO 318783B1
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- Prior art keywords
- peptide
- amino acid
- epo
- peptide according
- peptides
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/484,635 US5773569A (en) | 1993-11-19 | 1995-06-07 | Compounds and peptides that bind to the erythropoietin receptor |
| US08/484,631 US5830851A (en) | 1993-11-19 | 1995-06-07 | Methods of administering peptides that bind to the erythropoietin receptor |
| PCT/US1996/009810 WO1996040749A1 (en) | 1995-06-07 | 1996-06-07 | Compounds and peptides that bind to the erythropoietin receptor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975729D0 NO975729D0 (no) | 1997-12-05 |
| NO975729L NO975729L (no) | 1998-02-05 |
| NO318783B1 true NO318783B1 (no) | 2005-05-09 |
Family
ID=27048076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19975729A NO318783B1 (no) | 1995-06-07 | 1997-12-05 | Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP0886648B8 (ko) |
| JP (3) | JP4050314B2 (ko) |
| KR (1) | KR100459984B1 (ko) |
| CN (1) | CN1192748A (ko) |
| AT (1) | ATE254138T1 (ko) |
| AU (1) | AU712713B2 (ko) |
| BR (1) | BR9609006A (ko) |
| CA (1) | CA2223833C (ko) |
| CZ (1) | CZ391097A3 (ko) |
| DE (1) | DE69630708T2 (ko) |
| ES (1) | ES2210374T3 (ko) |
| HU (1) | HUP9901069A2 (ko) |
| IL (1) | IL122417A0 (ko) |
| NO (1) | NO318783B1 (ko) |
| NZ (1) | NZ310804A (ko) |
| PL (1) | PL185040B1 (ko) |
| TR (1) | TR199701557T2 (ko) |
| WO (1) | WO1996040749A1 (ko) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773569A (en) * | 1993-11-19 | 1998-06-30 | Affymax Technologies N.V. | Compounds and peptides that bind to the erythropoietin receptor |
| US5830851A (en) * | 1993-11-19 | 1998-11-03 | Affymax Technologies N.V. | Methods of administering peptides that bind to the erythropoietin receptor |
| US5767078A (en) * | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
| US6121416A (en) * | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| DE19904406A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Substituierte Pyrazolcarbonsäuren |
| DE19904396A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Substituierte Pyrazolbenzylamin-Derivate |
| US6703480B1 (en) | 1999-11-24 | 2004-03-09 | Palani Balu | Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use |
| US7259146B2 (en) | 2000-05-26 | 2007-08-21 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective peptides |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US7208145B2 (en) | 2002-12-31 | 2007-04-24 | Nektar Therapeutics Al, Corporation | Polymeric reagents comprising a ketone or a related functional group |
| CA2525568C (en) | 2003-05-12 | 2017-07-25 | Affymax, Inc. | Novel peptides that bind to the erythropoietin receptor |
| CN1820024B (zh) | 2003-05-12 | 2011-06-22 | 阿费麦克斯公司 | 新的聚(乙二醇)修饰的化合物及其用途 |
| EP2204193A3 (en) | 2003-05-12 | 2010-08-18 | Affymax, Inc. | Novel spacer moiety for poly(ethylene glycol)-modified peptide-based compounds |
| EA010099B1 (ru) | 2003-05-12 | 2008-06-30 | Афимакс, Инк. | Пептиды, которые связываются с рецептором к эритропоэтину, и способы их применения |
| PT2644206T (pt) | 2003-05-23 | 2019-07-10 | Nektar Therapeutics | Derivados de peg contendo duas cadeias de peg |
| CN102172405B (zh) | 2003-09-17 | 2014-11-12 | 耐科塔医药公司 | 多支链聚合物的药物前体 |
| PL1694363T3 (pl) | 2003-12-16 | 2014-07-31 | Nektar Therapeutics | Monodyspersyjne kompozycje PEGylowanego naloksolu |
| DK1725580T3 (da) * | 2004-03-17 | 2009-03-23 | Aplagen Gmbh | Isosterisk transformation |
| US9085659B2 (en) | 2004-05-03 | 2015-07-21 | Nektar Therapeutics | Polymer derivatives comprising an imide branching point |
| WO2005108463A2 (en) | 2004-05-03 | 2005-11-17 | Nektar Therapeutics Al, Corporation | Branched polyethylen glycol derivates comprising an acetal or ketal branching point |
| US7589063B2 (en) | 2004-12-14 | 2009-09-15 | Aplagen Gmbh | Molecules which promote hematopoiesis |
| JP2008519589A (ja) * | 2004-11-10 | 2008-06-12 | アプラゲン ゲーエムベーハー | 造血を促進する分子 |
| AU2005310189A1 (en) * | 2004-11-11 | 2006-06-08 | Affymax, Inc. | Novel peptides that bind to the erythropoietin receptor |
| JPWO2006115274A1 (ja) * | 2005-04-26 | 2008-12-18 | 味の素株式会社 | 骨髄赤血球前駆細胞分化促進剤 |
| US7550433B2 (en) | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| CA2648732A1 (en) * | 2005-06-23 | 2006-12-28 | Aplagen Gmbh | Supravalent compounds |
| CA3079319A1 (en) * | 2005-08-05 | 2007-02-15 | Araim Pharmaceuticals, Inc. | Tissue protective peptides and uses thereof |
| CA2680228A1 (en) * | 2006-03-09 | 2007-09-13 | Aplagen Gmbh | Modified molecules which promote hematopoiesis |
| EP3669894A3 (en) | 2006-06-30 | 2020-08-26 | Syntab Therapeutics GmbH | Novel multifunctional compounds for pharmaceutical purposes |
| JP2010520855A (ja) | 2007-01-31 | 2010-06-17 | アフィーマックス・インコーポレイテッド | 修飾基をポリペプチドおよびその他の高分子に結合するための窒素ベースのリンカー |
| EP2018835B1 (de) | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
| CN101456911A (zh) * | 2007-12-12 | 2009-06-17 | 江苏豪森药业股份有限公司 | 促红细胞生成素模拟肽衍生物及其可药用盐和其制备方法与用途 |
| CA2719940A1 (en) * | 2008-03-26 | 2009-11-26 | Orthologic Corp. | Methods for treating acute myocardial infarction |
| WO2010014258A2 (en) | 2008-08-01 | 2010-02-04 | Nektar Therapeutics Al, Corporation | Conjugates having a releasable linkage |
| JP5588983B2 (ja) | 2008-08-11 | 2014-09-10 | ウェルズ ファーゴ バンク ナショナル アソシエイション | マルチアームポリマーアルカノエートコンジュゲート |
| JP5766118B2 (ja) | 2008-09-11 | 2015-08-19 | ウェルズ ファーゴ バンク ナショナル アソシエイション | ポリマー性アルファ−ヒドロキシアルデヒドおよびケトン反応剤ならびに抱合方法 |
| WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| KR101647164B1 (ko) * | 2008-09-26 | 2016-08-09 | 암브룩스, 인코포레이티드 | 변형된 동물 에리트로포이에틴 폴리펩티드 및 이의 용도 |
| US20120190574A1 (en) * | 2009-06-19 | 2012-07-26 | The Arizona Board of Regents, A body Corporate of the State of Arizona for and on behalf of Arizona | Compound Arrays for Sample Profiling |
| WO2011012306A2 (en) | 2009-07-30 | 2011-02-03 | Aplagen Gmbh | Use of emps for antagonising epo-stimulatory effects on epo-responsive tumors while maintaining erythropoiesis |
| DK2590666T3 (en) | 2010-07-06 | 2017-07-17 | Augustinus Bader | TOPICAL APPLICATION OF ERYTHROPOIETIN FOR USE IN THE TREATMENT OF DAMAGE OF THE CORNS |
| US20130331443A1 (en) | 2010-12-22 | 2013-12-12 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of taxane-based compounds |
| US10894087B2 (en) | 2010-12-22 | 2021-01-19 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds |
| US20140088021A1 (en) | 2011-05-27 | 2014-03-27 | Nektar Therapeutics | Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds |
| WO2013171810A1 (ja) | 2012-05-14 | 2013-11-21 | パナソニック株式会社 | 耐熱性抗体提示ファージを得る方法 |
| CN103450348B (zh) * | 2012-05-29 | 2016-03-30 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种促红细胞生成素模拟肽、其制备方法和用途 |
| CN106608906A (zh) * | 2015-10-22 | 2017-05-03 | 天津药物研究院有限公司 | 一种具有刺激红细胞生成功能的环形多肽的制备及其应用 |
| CN106928338A (zh) * | 2015-12-31 | 2017-07-07 | 杭州阿德莱诺泰制药技术有限公司 | 促红细胞生成素肽及衍生物和聚合物、制备方法和应用 |
| GB201609083D0 (en) | 2016-05-24 | 2016-07-06 | Syntab Therapeutics Gmbh | Synthetic compound |
| KR20210060536A (ko) * | 2018-09-14 | 2021-05-26 | 에포-메드 가부시키가이샤 | 항에리트로포이에틴 수용체 펩티드 |
| CN114206322B (zh) | 2019-06-10 | 2024-08-16 | 瑞必治公司 | 载体基制剂及相关方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210501A (en) * | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| WO1990008822A1 (en) * | 1989-02-03 | 1990-08-09 | Genetics Institute, Inc. | Erythropoietin receptor |
| DE3924746A1 (de) * | 1989-07-26 | 1991-01-31 | Behringwerke Ag | Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper |
| US5767078A (en) * | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
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1996
- 1996-06-07 PL PL96323858A patent/PL185040B1/pl not_active IP Right Cessation
- 1996-06-07 CZ CZ973910A patent/CZ391097A3/cs unknown
- 1996-06-07 CA CA2223833A patent/CA2223833C/en not_active Expired - Fee Related
- 1996-06-07 CN CN96196094A patent/CN1192748A/zh active Pending
- 1996-06-07 DE DE69630708T patent/DE69630708T2/de not_active Expired - Lifetime
- 1996-06-07 AT AT96919296T patent/ATE254138T1/de not_active IP Right Cessation
- 1996-06-07 TR TR97/01557T patent/TR199701557T2/xx unknown
- 1996-06-07 EP EP96919296A patent/EP0886648B8/en not_active Expired - Lifetime
- 1996-06-07 WO PCT/US1996/009810 patent/WO1996040749A1/en active IP Right Grant
- 1996-06-07 KR KR1019970709231A patent/KR100459984B1/ko not_active IP Right Cessation
- 1996-06-07 IL IL12241796A patent/IL122417A0/xx unknown
- 1996-06-07 EP EP03025811A patent/EP1510524A3/en not_active Withdrawn
- 1996-06-07 JP JP50202397A patent/JP4050314B2/ja not_active Expired - Fee Related
- 1996-06-07 NZ NZ310804A patent/NZ310804A/xx not_active IP Right Cessation
- 1996-06-07 ES ES96919296T patent/ES2210374T3/es not_active Expired - Lifetime
- 1996-06-07 BR BR9609006-5A patent/BR9609006A/pt unknown
- 1996-06-07 HU HU9901069A patent/HUP9901069A2/hu unknown
- 1996-06-07 AU AU61667/96A patent/AU712713B2/en not_active Ceased
-
1997
- 1997-12-05 NO NO19975729A patent/NO318783B1/no not_active IP Right Cessation
-
2007
- 2007-07-18 JP JP2007186814A patent/JP2007277264A/ja active Pending
-
2009
- 2009-08-31 JP JP2009200615A patent/JP2009280616A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007277264A (ja) | 2007-10-25 |
| EP0886648A4 (en) | 2000-01-12 |
| AU6166796A (en) | 1996-12-30 |
| IL122417A0 (en) | 1998-06-15 |
| HUP9901069A2 (hu) | 1999-07-28 |
| DE69630708T2 (de) | 2004-08-05 |
| EP1510524A3 (en) | 2006-06-07 |
| CA2223833C (en) | 2010-12-21 |
| EP0886648B8 (en) | 2004-03-03 |
| EP0886648A1 (en) | 1998-12-30 |
| JP4050314B2 (ja) | 2008-02-20 |
| BR9609006A (pt) | 1999-12-14 |
| ATE254138T1 (de) | 2003-11-15 |
| EP0886648B1 (en) | 2003-11-12 |
| CA2223833A1 (en) | 1996-12-19 |
| DE69630708D1 (de) | 2003-12-18 |
| EP1510524A2 (en) | 2005-03-02 |
| TR199701557T2 (xx) | 2002-06-21 |
| KR100459984B1 (ko) | 2005-06-20 |
| WO1996040749A1 (en) | 1996-12-19 |
| CN1192748A (zh) | 1998-09-09 |
| AU712713B2 (en) | 1999-11-11 |
| NO975729L (no) | 1998-02-05 |
| JP2009280616A (ja) | 2009-12-03 |
| PL185040B1 (pl) | 2003-02-28 |
| KR19990022656A (ko) | 1999-03-25 |
| PL323858A1 (en) | 1998-04-27 |
| CZ391097A3 (cs) | 1998-07-15 |
| ES2210374T3 (es) | 2004-07-01 |
| NO975729D0 (no) | 1997-12-05 |
| JPH11507367A (ja) | 1999-06-29 |
| NZ310804A (en) | 1998-10-28 |
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| MM1K | Lapsed by not paying the annual fees |