NO314191B1 - Sammensetning omfattende en nukleinsyresekvens som koder for MN-protein samt fremgangsmåte for fremstilling av disse, og anvendelse derav ivaksine og diagnostikk - Google Patents

Sammensetning omfattende en nukleinsyresekvens som koder for MN-protein samt fremgangsmåte for fremstilling av disse, og anvendelse derav ivaksine og diagnostikk Download PDF

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Publication number
NO314191B1
NO314191B1 NO19943344A NO943344A NO314191B1 NO 314191 B1 NO314191 B1 NO 314191B1 NO 19943344 A NO19943344 A NO 19943344A NO 943344 A NO943344 A NO 943344A NO 314191 B1 NO314191 B1 NO 314191B1
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NO
Norway
Prior art keywords
protein
polypeptide
cells
antibody
proteins
Prior art date
Application number
NO19943344A
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English (en)
Norwegian (no)
Other versions
NO943344L (no
NO943344D0 (no
Inventor
Jan Zavada
Silvia Pastorekova
Jaromir Pastorek
Original Assignee
Inst Of Virology Slovak Academ
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25745325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO314191(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Inst Of Virology Slovak Academ filed Critical Inst Of Virology Slovak Academ
Publication of NO943344L publication Critical patent/NO943344L/no
Publication of NO943344D0 publication Critical patent/NO943344D0/no
Publication of NO314191B1 publication Critical patent/NO314191B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO19943344A 1992-03-11 1994-09-09 Sammensetning omfattende en nukleinsyresekvens som koder for MN-protein samt fremgangsmåte for fremstilling av disse, og anvendelse derav ivaksine og diagnostikk NO314191B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CS70992 1992-03-11
US07/964,589 US5387676A (en) 1992-03-11 1992-10-21 MN gene and protein
PCT/US1993/002024 WO1993018152A1 (en) 1992-03-11 1993-03-08 Mn gene and protein

Publications (3)

Publication Number Publication Date
NO943344L NO943344L (no) 1994-09-09
NO943344D0 NO943344D0 (no) 1994-09-09
NO314191B1 true NO314191B1 (no) 2003-02-10

Family

ID=25745325

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19943344A NO314191B1 (no) 1992-03-11 1994-09-09 Sammensetning omfattende en nukleinsyresekvens som koder for MN-protein samt fremgangsmåte for fremstilling av disse, og anvendelse derav ivaksine og diagnostikk

Country Status (8)

Country Link
US (5) US5387676A (enExample)
EP (1) EP0637336B1 (enExample)
JP (3) JP3755536B2 (enExample)
AU (1) AU669694B2 (enExample)
CA (1) CA2131826C (enExample)
DE (1) DE69325577T2 (enExample)
NO (1) NO314191B1 (enExample)
WO (1) WO1993018152A1 (enExample)

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US5989838A (en) * 1992-03-11 1999-11-23 Institute Of Virology, Slovak Academy Of Sciences Immunological methods of detecting MN proteins and MN polypeptides
US5981711A (en) * 1992-03-11 1999-11-09 Institute Of Virology, Slovak Academy Of Sciences MN-specific antibodies and hybridomas
US6297041B1 (en) 1992-03-11 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US5387676A (en) * 1992-03-11 1995-02-07 Ciba Corning Diagnostics Corp. MN gene and protein
US6204370B1 (en) * 1992-03-11 2001-03-20 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6774117B1 (en) 1992-03-11 2004-08-10 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US5972353A (en) * 1992-03-11 1999-10-26 Institute Of Virology, Slovak Academy Of Sciences MN proteins, polypeptides, fusion proteins and fusion polypeptides
US6027887A (en) * 1992-03-11 2000-02-22 Institute Of Virology, Solvak Academy Of Sciences MN gene and protein
US6069242A (en) * 1992-03-11 2000-05-30 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US5955075A (en) * 1992-03-11 1999-09-21 Institute Of Virology, Slovak Academy Of Sciences Method of inhibiting tumor growth using antibodies to MN protein
US6297051B1 (en) 1997-01-24 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6093548A (en) * 1992-03-11 2000-07-25 Institute Of Virology, Slovak Academy Of Sciences Detection and quantitation of MN-specific antibodies.
CA2192678C (en) * 1994-06-15 2010-12-14 Jan Zavada Mn gene and protein
EP0763110B9 (en) * 1994-06-15 2005-09-14 Institute Of Virology Mn gene and protein
US5744460A (en) * 1996-03-07 1998-04-28 Novartis Corporation Combination for treatment of proliferative diseases
US5858673A (en) * 1996-06-24 1999-01-12 Charlotte-Mecklenburg Hospital Authority Method for detecting prostate cells
US6087098A (en) 1997-04-15 2000-07-11 The Trustees Of Columbia University In The City Of New York Enhanced reverse transcriptase polymerase chain assay to detect MN in patients with renal cell carcinoma
US7713704B1 (en) 1998-10-23 2010-05-11 Institute Of Virology Of The Slovak Academy Of Science MN gene and protein
US6403327B1 (en) 1999-08-05 2002-06-11 The Regents Of The University Of California Diagnostic method using expression of MN/CA9 protein in ASCUS Pap smears
US6379907B1 (en) 1999-08-05 2002-04-30 The Regents Of The University Of California Diagnostic method using expression of MN/CA9 protein in AGUS Pap smears
US20080146780A1 (en) * 1999-10-22 2008-06-19 Jan Zavada MN Gene and Protein
US20100135980A1 (en) * 2000-10-16 2010-06-03 Rodriguez Victorio C Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging, disorders of aging, cancer, as growth factors, and as an alternative to stem cell therapy
US20040077081A1 (en) * 2001-02-07 2004-04-22 Egbert Oosterwijk Hybridoma cell line g250 and its use for producing monoclonal antibodies
EP1733736B1 (en) 2001-02-07 2015-02-25 Wilex AG Method of producing recombinant antibodies against tumours
US20030157111A1 (en) * 2001-04-23 2003-08-21 Ayelet Chajut 76A11 polypeptide and uses thereof
AU2002351208A1 (en) * 2001-12-03 2003-06-17 Abgenix, Inc. Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
US7910549B2 (en) 2001-12-13 2011-03-22 Institute Of Virology Of The Slovak Academy Of Sciences MN gene and protein
ES2365606T3 (es) 2002-02-13 2011-10-07 Ludwig Institute For Cancer Research Ltd. Anticuerpos contra gm-csf quiméricos.
CA2477163C (en) 2002-02-21 2010-07-27 Institute Of Virology Soluble form of carbonic anhydrase ix (s-ca-ix), assays to detect s-ca ix, and ca ix's coexpression with her-2/neu/c-erbb-2, and ca ix-specific monoclonal antibodies to non-immunodominant epitopes
SI2508596T1 (sl) 2002-02-21 2016-01-29 Institute Of Virology Slovak Academy Of Sciences Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe
US20090162382A1 (en) * 2002-03-01 2009-06-25 Bernett Matthew J Optimized ca9 antibodies and methods of using the same
WO2003089659A1 (en) * 2002-04-16 2003-10-30 The Regents Of The University Of California Methods or renal cell carcinoma prognosis and treatment selection with carbonic anhydrase ix
US20030232030A1 (en) * 2002-06-12 2003-12-18 L'oreal Compositions containing at least one oil structured with at least one silicone-polyamide polymer, and at least one gelling agent and methods of using the same
EP1524995B1 (en) * 2002-07-01 2011-12-21 Wilex AG Co-administration of cg250 and il-2 or ifn-alpha for treating cancer such as renal cell carcinomas
US20090252738A1 (en) * 2002-08-23 2009-10-08 Novartis Vaccines And Diagnostics, Inc. Compositions and methods of therapy for cancers characterized by expression of the tumor-associated antigen mn/ca ix
US7550424B2 (en) 2002-11-26 2009-06-23 Institute Of Virology Slovak Academy Of Sciences CA IX-specific inhibitors
US7524634B2 (en) * 2003-10-16 2009-04-28 Institute Of Virology, Slovak Academy Of Sciences MN/CA IX and cancer prognosis
AU2005241093B2 (en) * 2004-05-04 2008-06-05 Institute Of Virology Of Slovak Academy Of Sciences MN/CA IX/ CA9 and renal cancer prognosis
JP2008505143A (ja) 2004-07-02 2008-02-21 ヴィレックス アクチェンゲゼルシャフト Ｇ２５０発現腫瘍の改善されたアジュバント療法
US20090196850A1 (en) 2005-01-06 2009-08-06 Novo Nordisk A/S Anti-Kir Combination Treatments and Methods
DOP2006000277A (es) 2005-12-12 2007-08-31 Bayer Pharmaceuticals Corp Anticuerpos anti mn y métodos para su utilización
US20080038251A1 (en) * 2006-03-20 2008-02-14 Silvia Pastorekova MN/CA IX and MAPK inhibition
JP5479099B2 (ja) 2006-10-12 2014-04-23 インスティトゥート オブ ヴァイロロジー Ｍｎ／ｃａ９スプライス変異体
US7820159B2 (en) * 2006-10-31 2010-10-26 Instiute of Virology of the Slovak Academy of Sciences MN/CA IX and EGFR pathway inhibition
US8097423B2 (en) * 2007-07-30 2012-01-17 Institute Of Virology MN/CA IX and breast cancer therapy
US7919006B2 (en) * 2007-10-31 2011-04-05 Freescale Semiconductor, Inc. Method of anti-stiction dimple formation under MEMS
RU2497543C2 (ru) * 2007-11-02 2013-11-10 Хелт Рисерч Инк. Композиции и способы применения белка са9 для стимуляции иммунного ответа
US8492520B2 (en) 2007-11-02 2013-07-23 Wilex Ag Binding epitopes for G250 antibody
US20120207672A1 (en) 2009-09-15 2012-08-16 Wilex Ag Selective detection of bone metastases in renal clear cell carcinoma
US8993347B2 (en) * 2009-12-17 2015-03-31 Cornell University Methods for detecting antibodies in mucosal samples and device for sampling mucosal material
ES2703572T3 (es) 2013-02-22 2019-03-11 Heidelberg Pharma Ag Tratamiento del cáncer basado en la estratificación de CAIX
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
WO2016070016A1 (en) 2014-10-31 2016-05-06 Massachusetts Institute Of Technology Compositions and methods for forming emulsions
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US20190170737A1 (en) 2016-09-19 2019-06-06 Massachusetts Institute Of Technology Systems including janus droplets
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US12274993B2 (en) 2019-09-18 2025-04-15 Massachusetts Institute Of Technology Systems and methods for affecting interactions of electromagnetic radiation with janus droplets for sensitive detection of species
EP4055056A1 (en) 2019-11-05 2022-09-14 Mabpro A.S. Humanized anti-ca ix antibodies and methods of their use

Family Cites Families (6)

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US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
WO1988008854A1 (en) * 1987-05-06 1988-11-17 Egbert Oosterwijk Monoclonal antibodies to renal cell carcinoma
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5387676A (en) * 1992-03-11 1995-02-07 Ciba Corning Diagnostics Corp. MN gene and protein
US5981711A (en) * 1992-03-11 1999-11-09 Institute Of Virology, Slovak Academy Of Sciences MN-specific antibodies and hybridomas
CA2192678C (en) * 1994-06-15 2010-12-14 Jan Zavada Mn gene and protein

Also Published As

Publication number Publication date
AU669694B2 (en) 1996-06-20
DE69325577D1 (de) 1999-08-12
AU3792793A (en) 1993-10-05
US5387676A (en) 1995-02-07
JPH07508160A (ja) 1995-09-14
JP3755536B2 (ja) 2006-03-15
EP0637336B1 (en) 1999-07-07
JP4624900B2 (ja) 2011-02-02
JP2011036254A (ja) 2011-02-24
US20070255043A1 (en) 2007-11-01
CA2131826A1 (en) 1993-09-16
JP4865896B2 (ja) 2012-02-01
JP2006083179A (ja) 2006-03-30
US20080221309A1 (en) 2008-09-11
US6004535A (en) 1999-12-21
EP0637336A1 (en) 1995-02-08
NO943344L (no) 1994-09-09
US6051226A (en) 2000-04-18
WO1993018152A1 (en) 1993-09-16
NO943344D0 (no) 1994-09-09
US7816496B2 (en) 2010-10-19
DE69325577T2 (de) 2000-01-13
CA2131826C (en) 2000-05-16

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