DE69325577T2 - Mn-gen und protein - Google Patents

Mn-gen und protein

Info

Publication number
DE69325577T2
DE69325577T2 DE69325577T DE69325577T DE69325577T2 DE 69325577 T2 DE69325577 T2 DE 69325577T2 DE 69325577 T DE69325577 T DE 69325577T DE 69325577 T DE69325577 T DE 69325577T DE 69325577 T2 DE69325577 T2 DE 69325577T2
Authority
DE
Germany
Prior art keywords
gene
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69325577T
Other languages
English (en)
Other versions
DE69325577D1 (de
Inventor
Jan Zavada
Silvia Pastorekova
Jaromir Pastorek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Virology (Slovak Academy of Science)
Bayer Corp
Original Assignee
Institute of Virology (Slovak Academy of Science)
Chiron Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25745325&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69325577(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Institute of Virology (Slovak Academy of Science), Chiron Diagnostics Corp filed Critical Institute of Virology (Slovak Academy of Science)
Publication of DE69325577D1 publication Critical patent/DE69325577D1/de
Application granted granted Critical
Publication of DE69325577T2 publication Critical patent/DE69325577T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
DE69325577T 1992-03-11 1993-03-08 Mn-gen und protein Expired - Lifetime DE69325577T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CS70992 1992-03-11
US07/964,589 US5387676A (en) 1992-03-11 1992-10-21 MN gene and protein
PCT/US1993/002024 WO1993018152A1 (en) 1992-03-11 1993-03-08 Mn gene and protein

Publications (2)

Publication Number Publication Date
DE69325577D1 DE69325577D1 (de) 1999-08-12
DE69325577T2 true DE69325577T2 (de) 2000-01-13

Family

ID=25745325

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69325577T Expired - Lifetime DE69325577T2 (de) 1992-03-11 1993-03-08 Mn-gen und protein

Country Status (8)

Country Link
US (5) US5387676A (de)
EP (1) EP0637336B1 (de)
JP (3) JP3755536B2 (de)
AU (1) AU669694B2 (de)
CA (1) CA2131826C (de)
DE (1) DE69325577T2 (de)
NO (1) NO314191B1 (de)
WO (1) WO1993018152A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069864A2 (en) 2006-10-12 2008-06-12 Bayer Pharmaceuticals Corporation Mn/ca9 splice variants
EP2508596A2 (de) 2002-02-21 2012-10-10 Bayer Healthcare MN/CA-IX-spezifische, von MN/CA-IX-defizienten Mäusen erzeugte monoklonale Antikörper und Verwendungsverfahren

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030206899A1 (en) * 1991-03-29 2003-11-06 Genentech, Inc. Vascular endothelial cell growth factor antagonists
US5989838A (en) * 1992-03-11 1999-11-23 Institute Of Virology, Slovak Academy Of Sciences Immunological methods of detecting MN proteins and MN polypeptides
US5981711A (en) * 1992-03-11 1999-11-09 Institute Of Virology, Slovak Academy Of Sciences MN-specific antibodies and hybridomas
US5972353A (en) * 1992-03-11 1999-10-26 Institute Of Virology, Slovak Academy Of Sciences MN proteins, polypeptides, fusion proteins and fusion polypeptides
US5387676A (en) * 1992-03-11 1995-02-07 Ciba Corning Diagnostics Corp. MN gene and protein
US5955075A (en) * 1992-03-11 1999-09-21 Institute Of Virology, Slovak Academy Of Sciences Method of inhibiting tumor growth using antibodies to MN protein
US6093548A (en) * 1992-03-11 2000-07-25 Institute Of Virology, Slovak Academy Of Sciences Detection and quantitation of MN-specific antibodies.
US6027887A (en) * 1992-03-11 2000-02-22 Institute Of Virology, Solvak Academy Of Sciences MN gene and protein
US6297051B1 (en) 1997-01-24 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6297041B1 (en) * 1992-03-11 2001-10-02 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6069242A (en) * 1992-03-11 2000-05-30 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6204370B1 (en) * 1992-03-11 2001-03-20 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
US6774117B1 (en) 1992-03-11 2004-08-10 Institute Of Virology, Slovak Academy Of Sciences MN gene and protein
AU2861695A (en) * 1994-06-15 1996-01-05 Ciba Corning Diagnostics Corp. Mn gene and protein
ATE296883T1 (de) * 1994-06-15 2005-06-15 Inst Virology Mn-gen und -protein
US5744460A (en) * 1996-03-07 1998-04-28 Novartis Corporation Combination for treatment of proliferative diseases
US5858673A (en) * 1996-06-24 1999-01-12 Charlotte-Mecklenburg Hospital Authority Method for detecting prostate cells
US6087098A (en) * 1997-04-15 2000-07-11 The Trustees Of Columbia University In The City Of New York Enhanced reverse transcriptase polymerase chain assay to detect MN in patients with renal cell carcinoma
US7713704B1 (en) 1998-10-23 2010-05-11 Institute Of Virology Of The Slovak Academy Of Science MN gene and protein
US6379907B1 (en) 1999-08-05 2002-04-30 The Regents Of The University Of California Diagnostic method using expression of MN/CA9 protein in AGUS Pap smears
US6403327B1 (en) 1999-08-05 2002-06-11 The Regents Of The University Of California Diagnostic method using expression of MN/CA9 protein in ASCUS Pap smears
US7910691B2 (en) * 1999-10-22 2011-03-22 Institute Of Virology Of The Slovak Academy Of Sciences MN gene and protein
US20100135980A1 (en) * 2000-10-16 2010-06-03 Rodriguez Victorio C Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging, disorders of aging, cancer, as growth factors, and as an alternative to stem cell therapy
EP1733736B1 (de) 2001-02-07 2015-02-25 Wilex AG Verfahren zur Herstellung von rekombinanten Antikörpern gegen Tumore
US20040077081A1 (en) * 2001-02-07 2004-04-22 Egbert Oosterwijk Hybridoma cell line g250 and its use for producing monoclonal antibodies
WO2002086089A2 (en) * 2001-04-23 2002-10-31 Quark Biotech, Inc. The 76a11 polypeptide and uses thereof
US7378091B2 (en) * 2001-12-03 2008-05-27 Amgen Fremont Inc. Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
US7910549B2 (en) * 2001-12-13 2011-03-22 Institute Of Virology Of The Slovak Academy Of Sciences MN gene and protein
WO2003068920A2 (en) 2002-02-13 2003-08-21 Ludwig Institute For Cancer Research Humanized gm-csf antibodies
DK1487972T3 (en) * 2002-02-21 2015-10-19 Inst Virology MN / CA IX-specific monoclonal antibodies generated from MN / CA IX-poor mice, as well as methods of use.
US20090162382A1 (en) * 2002-03-01 2009-06-25 Bernett Matthew J Optimized ca9 antibodies and methods of using the same
ATE437235T1 (de) * 2002-04-16 2009-08-15 Univ California Verfahren zur prognose von nierenzellkarzinom und behandlungsauswahl mit carboanhydrase ix
US20030232030A1 (en) * 2002-06-12 2003-12-18 L'oreal Compositions containing at least one oil structured with at least one silicone-polyamide polymer, and at least one gelling agent and methods of using the same
AU2003280442B2 (en) 2002-07-01 2009-02-05 Wilex Ag Co-administration of CG250 and IL-2 or IFN-alpha for treating cancer such as renal cell carcinomas
US20090252738A1 (en) * 2002-08-23 2009-10-08 Novartis Vaccines And Diagnostics, Inc. Compositions and methods of therapy for cancers characterized by expression of the tumor-associated antigen mn/ca ix
SI2594265T1 (sl) 2002-11-26 2016-03-31 Institute Of Virology Slovak Academy Of Sciences CA-IX specifični inhibitorji
US7524634B2 (en) * 2003-10-16 2009-04-28 Institute Of Virology, Slovak Academy Of Sciences MN/CA IX and cancer prognosis
EP1743038A4 (de) * 2004-05-04 2007-11-21 Bayer Healthcare Mn/ca ix/ca9 und nierenkrebsprognose
US7691375B2 (en) 2004-07-02 2010-04-06 Wilex Ag Adjuvant theraphy of G250-expressing tumors
US20090196850A1 (en) 2005-01-06 2009-08-06 Novo Nordisk A/S Anti-Kir Combination Treatments and Methods
DOP2006000277A (es) 2005-12-12 2007-08-31 Bayer Pharmaceuticals Corp Anticuerpos anti mn y métodos para su utilización
US20080038251A1 (en) * 2006-03-20 2008-02-14 Silvia Pastorekova MN/CA IX and MAPK inhibition
US7820159B2 (en) * 2006-10-31 2010-10-26 Instiute of Virology of the Slovak Academy of Sciences MN/CA IX and EGFR pathway inhibition
US8097423B2 (en) * 2007-07-30 2012-01-17 Institute Of Virology MN/CA IX and breast cancer therapy
US7919006B2 (en) * 2007-10-31 2011-04-05 Freescale Semiconductor, Inc. Method of anti-stiction dimple formation under MEMS
EP2219668A1 (de) * 2007-11-02 2010-08-25 Wilex AG Bindungsepitope für g250-antikörper
WO2009059281A1 (en) * 2007-11-02 2009-05-07 Health Research Inc. Compositions and methods for using ca9 protein to stimulate an immune response
ES2632353T3 (es) 2009-09-15 2017-09-12 Wilex Ag Detección selectiva de metástasis en carcinoma renal de células claras
US8993347B2 (en) 2009-12-17 2015-03-31 Cornell University Methods for detecting antibodies in mucosal samples and device for sampling mucosal material
MX363845B (es) 2013-02-22 2019-04-05 Wilex Ag Anticuerpo anti-caix para usarse en el tratamiento de carcinoma de células claras renales.
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
WO2016070016A1 (en) 2014-10-31 2016-05-06 Massachusetts Institute Of Technology Compositions and methods for forming emulsions
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CA3156540A1 (en) 2019-11-05 2021-05-14 Miriam Zatovicova Humanized anti-ca ix antibodies and methods of their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
WO1988008854A1 (en) * 1987-05-06 1988-11-17 Egbert Oosterwijk Monoclonal antibodies to renal cell carcinoma
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5981711A (en) * 1992-03-11 1999-11-09 Institute Of Virology, Slovak Academy Of Sciences MN-specific antibodies and hybridomas
US5387676A (en) * 1992-03-11 1995-02-07 Ciba Corning Diagnostics Corp. MN gene and protein
AU2861695A (en) * 1994-06-15 1996-01-05 Ciba Corning Diagnostics Corp. Mn gene and protein

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2508596A2 (de) 2002-02-21 2012-10-10 Bayer Healthcare MN/CA-IX-spezifische, von MN/CA-IX-defizienten Mäusen erzeugte monoklonale Antikörper und Verwendungsverfahren
EP3031910A1 (de) 2002-02-21 2016-06-15 Institute Of Virology Mn/ca-ix-spezifische, monoklonale antikörper, die von mn/ca-ix-defizienten mäusen erzeugt sind, und verfahren zur verwendung
WO2008069864A2 (en) 2006-10-12 2008-06-12 Bayer Pharmaceuticals Corporation Mn/ca9 splice variants

Also Published As

Publication number Publication date
US20070255043A1 (en) 2007-11-01
US6051226A (en) 2000-04-18
JPH07508160A (ja) 1995-09-14
CA2131826C (en) 2000-05-16
JP2011036254A (ja) 2011-02-24
NO314191B1 (no) 2003-02-10
EP0637336A1 (de) 1995-02-08
JP3755536B2 (ja) 2006-03-15
AU3792793A (en) 1993-10-05
NO943344L (no) 1994-09-09
US5387676A (en) 1995-02-07
AU669694B2 (en) 1996-06-20
WO1993018152A1 (en) 1993-09-16
DE69325577D1 (de) 1999-08-12
US20080221309A1 (en) 2008-09-11
JP4624900B2 (ja) 2011-02-02
EP0637336B1 (de) 1999-07-07
NO943344D0 (no) 1994-09-09
US7816496B2 (en) 2010-10-19
JP2006083179A (ja) 2006-03-30
CA2131826A1 (en) 1993-09-16
JP4865896B2 (ja) 2012-02-01
US6004535A (en) 1999-12-21

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Legal Events

Date Code Title Description
8363 Opposition against the patent