CA2131826C - Mn gene and protein - Google Patents
Mn gene and protein Download PDFInfo
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- CA2131826C CA2131826C CA002131826A CA2131826A CA2131826C CA 2131826 C CA2131826 C CA 2131826C CA 002131826 A CA002131826 A CA 002131826A CA 2131826 A CA2131826 A CA 2131826A CA 2131826 C CA2131826 C CA 2131826C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CSPV709-92 | 1992-03-11 | ||
| CS70992 | 1992-03-11 | ||
| US07/964,589 US5387676A (en) | 1992-03-11 | 1992-10-21 | MN gene and protein |
| US07/964,589 | 1992-10-21 | ||
| PCT/US1993/002024 WO1993018152A1 (en) | 1992-03-11 | 1993-03-08 | Mn gene and protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2131826A1 CA2131826A1 (en) | 1993-09-16 |
| CA2131826C true CA2131826C (en) | 2000-05-16 |
Family
ID=25745325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002131826A Expired - Lifetime CA2131826C (en) | 1992-03-11 | 1993-03-08 | Mn gene and protein |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US5387676A (enExample) |
| EP (1) | EP0637336B1 (enExample) |
| JP (3) | JP3755536B2 (enExample) |
| AU (1) | AU669694B2 (enExample) |
| CA (1) | CA2131826C (enExample) |
| DE (1) | DE69325577T2 (enExample) |
| NO (1) | NO314191B1 (enExample) |
| WO (1) | WO1993018152A1 (enExample) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206899A1 (en) * | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US5989838A (en) * | 1992-03-11 | 1999-11-23 | Institute Of Virology, Slovak Academy Of Sciences | Immunological methods of detecting MN proteins and MN polypeptides |
| US5981711A (en) * | 1992-03-11 | 1999-11-09 | Institute Of Virology, Slovak Academy Of Sciences | MN-specific antibodies and hybridomas |
| US6297041B1 (en) | 1992-03-11 | 2001-10-02 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5387676A (en) * | 1992-03-11 | 1995-02-07 | Ciba Corning Diagnostics Corp. | MN gene and protein |
| US6204370B1 (en) * | 1992-03-11 | 2001-03-20 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US6774117B1 (en) | 1992-03-11 | 2004-08-10 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5972353A (en) * | 1992-03-11 | 1999-10-26 | Institute Of Virology, Slovak Academy Of Sciences | MN proteins, polypeptides, fusion proteins and fusion polypeptides |
| US6027887A (en) * | 1992-03-11 | 2000-02-22 | Institute Of Virology, Solvak Academy Of Sciences | MN gene and protein |
| US6069242A (en) * | 1992-03-11 | 2000-05-30 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5955075A (en) * | 1992-03-11 | 1999-09-21 | Institute Of Virology, Slovak Academy Of Sciences | Method of inhibiting tumor growth using antibodies to MN protein |
| US6297051B1 (en) | 1997-01-24 | 2001-10-02 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US6093548A (en) * | 1992-03-11 | 2000-07-25 | Institute Of Virology, Slovak Academy Of Sciences | Detection and quantitation of MN-specific antibodies. |
| CA2192678C (en) * | 1994-06-15 | 2010-12-14 | Jan Zavada | Mn gene and protein |
| EP0763110B9 (en) * | 1994-06-15 | 2005-09-14 | Institute Of Virology | Mn gene and protein |
| US5744460A (en) * | 1996-03-07 | 1998-04-28 | Novartis Corporation | Combination for treatment of proliferative diseases |
| US5858673A (en) * | 1996-06-24 | 1999-01-12 | Charlotte-Mecklenburg Hospital Authority | Method for detecting prostate cells |
| US6087098A (en) | 1997-04-15 | 2000-07-11 | The Trustees Of Columbia University In The City Of New York | Enhanced reverse transcriptase polymerase chain assay to detect MN in patients with renal cell carcinoma |
| US7713704B1 (en) | 1998-10-23 | 2010-05-11 | Institute Of Virology Of The Slovak Academy Of Science | MN gene and protein |
| US6403327B1 (en) | 1999-08-05 | 2002-06-11 | The Regents Of The University Of California | Diagnostic method using expression of MN/CA9 protein in ASCUS Pap smears |
| US6379907B1 (en) | 1999-08-05 | 2002-04-30 | The Regents Of The University Of California | Diagnostic method using expression of MN/CA9 protein in AGUS Pap smears |
| US20080146780A1 (en) * | 1999-10-22 | 2008-06-19 | Jan Zavada | MN Gene and Protein |
| US20100135980A1 (en) * | 2000-10-16 | 2010-06-03 | Rodriguez Victorio C | Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging, disorders of aging, cancer, as growth factors, and as an alternative to stem cell therapy |
| US20040077081A1 (en) * | 2001-02-07 | 2004-04-22 | Egbert Oosterwijk | Hybridoma cell line g250 and its use for producing monoclonal antibodies |
| EP1733736B1 (en) | 2001-02-07 | 2015-02-25 | Wilex AG | Method of producing recombinant antibodies against tumours |
| US20030157111A1 (en) * | 2001-04-23 | 2003-08-21 | Ayelet Chajut | 76A11 polypeptide and uses thereof |
| AU2002351208A1 (en) * | 2001-12-03 | 2003-06-17 | Abgenix, Inc. | Antibodies against carbonic anhydrase IX (CA IX) tumor antigen |
| US7910549B2 (en) | 2001-12-13 | 2011-03-22 | Institute Of Virology Of The Slovak Academy Of Sciences | MN gene and protein |
| ES2365606T3 (es) | 2002-02-13 | 2011-10-07 | Ludwig Institute For Cancer Research Ltd. | Anticuerpos contra gm-csf quiméricos. |
| CA2477163C (en) | 2002-02-21 | 2010-07-27 | Institute Of Virology | Soluble form of carbonic anhydrase ix (s-ca-ix), assays to detect s-ca ix, and ca ix's coexpression with her-2/neu/c-erbb-2, and ca ix-specific monoclonal antibodies to non-immunodominant epitopes |
| SI2508596T1 (sl) | 2002-02-21 | 2016-01-29 | Institute Of Virology Slovak Academy Of Sciences | Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe |
| US20090162382A1 (en) * | 2002-03-01 | 2009-06-25 | Bernett Matthew J | Optimized ca9 antibodies and methods of using the same |
| WO2003089659A1 (en) * | 2002-04-16 | 2003-10-30 | The Regents Of The University Of California | Methods or renal cell carcinoma prognosis and treatment selection with carbonic anhydrase ix |
| US20030232030A1 (en) * | 2002-06-12 | 2003-12-18 | L'oreal | Compositions containing at least one oil structured with at least one silicone-polyamide polymer, and at least one gelling agent and methods of using the same |
| EP1524995B1 (en) * | 2002-07-01 | 2011-12-21 | Wilex AG | Co-administration of cg250 and il-2 or ifn-alpha for treating cancer such as renal cell carcinomas |
| US20090252738A1 (en) * | 2002-08-23 | 2009-10-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions and methods of therapy for cancers characterized by expression of the tumor-associated antigen mn/ca ix |
| US7550424B2 (en) | 2002-11-26 | 2009-06-23 | Institute Of Virology Slovak Academy Of Sciences | CA IX-specific inhibitors |
| US7524634B2 (en) * | 2003-10-16 | 2009-04-28 | Institute Of Virology, Slovak Academy Of Sciences | MN/CA IX and cancer prognosis |
| AU2005241093B2 (en) * | 2004-05-04 | 2008-06-05 | Institute Of Virology Of Slovak Academy Of Sciences | MN/CA IX/ CA9 and renal cancer prognosis |
| JP2008505143A (ja) | 2004-07-02 | 2008-02-21 | ヴィレックス アクチェンゲゼルシャフト | Ｇ２５０発現腫瘍の改善されたアジュバント療法 |
| US20090196850A1 (en) | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| DOP2006000277A (es) | 2005-12-12 | 2007-08-31 | Bayer Pharmaceuticals Corp | Anticuerpos anti mn y métodos para su utilización |
| US20080038251A1 (en) * | 2006-03-20 | 2008-02-14 | Silvia Pastorekova | MN/CA IX and MAPK inhibition |
| JP5479099B2 (ja) | 2006-10-12 | 2014-04-23 | インスティトゥート オブ ヴァイロロジー | Ｍｎ／ｃａ９スプライス変異体 |
| US7820159B2 (en) * | 2006-10-31 | 2010-10-26 | Instiute of Virology of the Slovak Academy of Sciences | MN/CA IX and EGFR pathway inhibition |
| US8097423B2 (en) * | 2007-07-30 | 2012-01-17 | Institute Of Virology | MN/CA IX and breast cancer therapy |
| US7919006B2 (en) * | 2007-10-31 | 2011-04-05 | Freescale Semiconductor, Inc. | Method of anti-stiction dimple formation under MEMS |
| RU2497543C2 (ru) * | 2007-11-02 | 2013-11-10 | Хелт Рисерч Инк. | Композиции и способы применения белка са9 для стимуляции иммунного ответа |
| US8492520B2 (en) | 2007-11-02 | 2013-07-23 | Wilex Ag | Binding epitopes for G250 antibody |
| US20120207672A1 (en) | 2009-09-15 | 2012-08-16 | Wilex Ag | Selective detection of bone metastases in renal clear cell carcinoma |
| US8993347B2 (en) * | 2009-12-17 | 2015-03-31 | Cornell University | Methods for detecting antibodies in mucosal samples and device for sampling mucosal material |
| ES2703572T3 (es) | 2013-02-22 | 2019-03-11 | Heidelberg Pharma Ag | Tratamiento del cáncer basado en la estratificación de CAIX |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| WO2016070016A1 (en) | 2014-10-31 | 2016-05-06 | Massachusetts Institute Of Technology | Compositions and methods for forming emulsions |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US20190170737A1 (en) | 2016-09-19 | 2019-06-06 | Massachusetts Institute Of Technology | Systems including janus droplets |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US12274993B2 (en) | 2019-09-18 | 2025-04-15 | Massachusetts Institute Of Technology | Systems and methods for affecting interactions of electromagnetic radiation with janus droplets for sensitive detection of species |
| EP4055056A1 (en) | 2019-11-05 | 2022-09-14 | Mabpro A.S. | Humanized anti-ca ix antibodies and methods of their use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| WO1988008854A1 (en) * | 1987-05-06 | 1988-11-17 | Egbert Oosterwijk | Monoclonal antibodies to renal cell carcinoma |
| IL162181A (en) * | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5387676A (en) * | 1992-03-11 | 1995-02-07 | Ciba Corning Diagnostics Corp. | MN gene and protein |
| US5981711A (en) * | 1992-03-11 | 1999-11-09 | Institute Of Virology, Slovak Academy Of Sciences | MN-specific antibodies and hybridomas |
| CA2192678C (en) * | 1994-06-15 | 2010-12-14 | Jan Zavada | Mn gene and protein |
-
1992
- 1992-10-21 US US07/964,589 patent/US5387676A/en not_active Expired - Lifetime
-
1993
- 1993-03-08 DE DE69325577T patent/DE69325577T2/de not_active Expired - Lifetime
- 1993-03-08 EP EP93907263A patent/EP0637336B1/en not_active Expired - Lifetime
- 1993-03-08 AU AU37927/93A patent/AU669694B2/en not_active Expired
- 1993-03-08 JP JP51592893A patent/JP3755536B2/ja not_active Expired - Lifetime
- 1993-03-08 CA CA002131826A patent/CA2131826C/en not_active Expired - Lifetime
- 1993-03-08 WO PCT/US1993/002024 patent/WO1993018152A1/en not_active Ceased
- 1993-12-30 US US08/177,093 patent/US6051226A/en not_active Expired - Lifetime
-
1994
- 1994-09-09 NO NO19943344A patent/NO314191B1/no not_active IP Right Cessation
- 1994-11-07 US US08/335,469 patent/US6004535A/en not_active Expired - Lifetime
-
2005
- 2005-10-12 JP JP2005297594A patent/JP4624900B2/ja not_active Expired - Lifetime
-
2007
- 2007-02-13 US US11/706,101 patent/US7816496B2/en not_active Expired - Fee Related
- 2007-10-31 US US11/932,697 patent/US20080221309A1/en not_active Abandoned
-
2010
- 2010-09-08 JP JP2010200720A patent/JP4865896B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU669694B2 (en) | 1996-06-20 |
| DE69325577D1 (de) | 1999-08-12 |
| AU3792793A (en) | 1993-10-05 |
| US5387676A (en) | 1995-02-07 |
| JPH07508160A (ja) | 1995-09-14 |
| JP3755536B2 (ja) | 2006-03-15 |
| EP0637336B1 (en) | 1999-07-07 |
| JP4624900B2 (ja) | 2011-02-02 |
| JP2011036254A (ja) | 2011-02-24 |
| US20070255043A1 (en) | 2007-11-01 |
| CA2131826A1 (en) | 1993-09-16 |
| JP4865896B2 (ja) | 2012-02-01 |
| JP2006083179A (ja) | 2006-03-30 |
| US20080221309A1 (en) | 2008-09-11 |
| US6004535A (en) | 1999-12-21 |
| EP0637336A1 (en) | 1995-02-08 |
| NO943344L (no) | 1994-09-09 |
| US6051226A (en) | 2000-04-18 |
| WO1993018152A1 (en) | 1993-09-16 |
| NO943344D0 (no) | 1994-09-09 |
| NO314191B1 (no) | 2003-02-10 |
| US7816496B2 (en) | 2010-10-19 |
| DE69325577T2 (de) | 2000-01-13 |
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| EEER | Examination request |