NO313756B1 - Syklopeptidforbindelser, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstillingderav, samt anvdendelse av forbindelsene til fremstilling avmedikamenter og immobiliserte ligander, og til rensing av integr - Google Patents
Syklopeptidforbindelser, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstillingderav, samt anvdendelse av forbindelsene til fremstilling avmedikamenter og immobiliserte ligander, og til rensing av integr Download PDFInfo
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- NO313756B1 NO313756B1 NO19941152A NO941152A NO313756B1 NO 313756 B1 NO313756 B1 NO 313756B1 NO 19941152 A NO19941152 A NO 19941152A NO 941152 A NO941152 A NO 941152A NO 313756 B1 NO313756 B1 NO 313756B1
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- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical class OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical compound CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920005990 polystyrene resin Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000012064 sodium phosphate buffer Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4310643A DE4310643A1 (de) | 1993-04-01 | 1993-04-01 | Cyclische Adhäsionsinhibitoren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO941152D0 NO941152D0 (no) | 1994-03-29 |
| NO941152L NO941152L (no) | 1994-10-03 |
| NO313756B1 true NO313756B1 (no) | 2002-11-25 |
Family
ID=6484433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19941152A NO313756B1 (no) | 1993-04-01 | 1994-03-29 | Syklopeptidforbindelser, fremgangsmåte for fremstilling derav, farmasöytiske preparater, fremgangsmåte for fremstillingderav, samt anvdendelse av forbindelsene til fremstilling avmedikamenter og immobiliserte ligander, og til rensing av integr |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5849692A (hu) |
| EP (1) | EP0632053B1 (hu) |
| JP (1) | JP3694332B2 (hu) |
| KR (1) | KR100304201B1 (hu) |
| CN (1) | CN1056851C (hu) |
| AT (1) | ATE184288T1 (hu) |
| AU (1) | AU684489B2 (hu) |
| CA (1) | CA2120303C (hu) |
| CZ (1) | CZ286768B6 (hu) |
| DE (2) | DE4310643A1 (hu) |
| DK (1) | DK0632053T3 (hu) |
| ES (1) | ES2138632T3 (hu) |
| GR (1) | GR3032074T3 (hu) |
| HU (1) | HUT69726A (hu) |
| NO (1) | NO313756B1 (hu) |
| PL (1) | PL178791B1 (hu) |
| RU (1) | RU2130030C1 (hu) |
| SK (1) | SK281828B6 (hu) |
| TW (1) | TW343198B (hu) |
| UA (1) | UA34436C2 (hu) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
| DE4415310A1 (de) * | 1994-04-30 | 1995-11-02 | Merck Patent Gmbh | Cyclopeptide |
| US7053041B1 (en) | 1996-05-31 | 2006-05-30 | The Scripps Research Institute | Methods and compositions useful for inhibition of αvβ5mediated angiogenesis |
| DE19534016A1 (de) * | 1995-09-14 | 1997-03-20 | Merck Patent Gmbh | Biotinderivate |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19538741A1 (de) * | 1995-10-18 | 1997-04-24 | Merck Patent Gmbh | Cyclopeptidderivate |
| DE19613933A1 (de) * | 1996-04-06 | 1997-10-09 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| SK163598A3 (en) | 1996-05-31 | 1999-06-11 | Scripps Research Inst | Methods and compositions useful for inhibition of angiogenesis |
| DE19736772A1 (de) * | 1997-08-23 | 1999-02-25 | Merck Patent Gmbh | Cyclopeptidderivate |
| CN1346282A (zh) | 1998-12-23 | 2002-04-24 | G.D.西尔公司 | 在肿瘤的治疗中使用环加氧酶－2－抑制剂与一种或多种抗肿瘤剂作为联合治疗的方法 |
| UA71608C2 (en) | 1999-03-11 | 2004-12-15 | Merck Patent Gmbh | A method for producing the cyclic pentapeptide |
| DE19933173A1 (de) | 1999-07-15 | 2001-01-18 | Merck Patent Gmbh | Cyclische Peptidderivate als Inhibitoren des Integrins alpha¶v¶beta¶6¶ |
| US6359015B1 (en) | 2000-02-28 | 2002-03-19 | The United States Of America As Represented By The Department Of Veterans Affairs | Method for antagonizing inhibition effects of alcohol on cell adhesion |
| US6624187B1 (en) * | 2000-06-12 | 2003-09-23 | Health Research, Inc. | Long wave length absorbing bacteriochlorin alkyl ether analogs |
| DE10040105A1 (de) | 2000-08-17 | 2002-02-28 | Merck Patent Gmbh | Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften |
| FR2814744B1 (fr) * | 2000-10-04 | 2002-11-29 | Commissariat Energie Atomique | Cyclopeptides, leur procede de preparation et leur utilisation comme inhibiteur ou activateur de l'angiogenese |
| CN1507354A (zh) * | 2001-03-02 | 2004-06-23 | ͨ��ҽ�ƹ�˾ | 通过给予整合蛋白αvβ3拮抗剂并与其它预防或治疗药剂配合来预防或者治疗炎性疾病或自身免疫疾病的方法 |
| US7879267B2 (en) * | 2001-08-02 | 2011-02-01 | J&J Vision Care, Inc. | Method for coating articles by mold transfer |
| JP2005525368A (ja) * | 2002-03-04 | 2005-08-25 | メディミューン，インコーポレーテッド | インテグリンαｖβ３アンタゴニストをＨＭＧ−ＣｏＡ還元酵素阻害剤またはビスフォスフォネートと併用投与する障害の予防または治療方法 |
| WO2003075957A1 (en) * | 2002-03-04 | 2003-09-18 | Medimmune, Inc. | The prevention or treatment of cancer using integrin alphavbeta3 antagonists in combination with other agents |
| EP1499352A4 (en) * | 2002-04-12 | 2006-10-11 | Medimmune Inc | ANTI-INTERLEUKIN-9 RECOMBINANT ANTIBODIES |
| GB0217017D0 (en) * | 2002-07-23 | 2002-08-28 | Bioacta Ltd | Peptide 2 |
| ITRM20020402A1 (it) * | 2002-07-29 | 2004-01-29 | Sigma Tau Ind Farmaceuti | Derivati fluoro-alchil-ciclopeptidi ad attivita' anti-integrine. |
| US6977272B2 (en) * | 2002-10-16 | 2005-12-20 | President And Fellows Of Harvard College | Method for antagonizing inhibition effects of alcohol on cell adhesion |
| CA2514653A1 (en) * | 2003-01-30 | 2004-08-12 | Medimmune, Inc. | Uses of integrin alphavbeta3 antagonists |
| AU2004229501B2 (en) | 2003-04-11 | 2011-08-18 | Medimmune, Llc | Recombinant IL-9 antibodies and uses thereof |
| US7351739B2 (en) * | 2004-04-30 | 2008-04-01 | Wellgen, Inc. | Bioactive compounds and methods of uses thereof |
| ITRM20040239A1 (it) * | 2004-05-13 | 2004-08-13 | Sigma Tau Ind Farmaceuti | Derivati ciclopeptidici ad attivita' antintegrine. |
| EP2422811A2 (en) | 2004-10-27 | 2012-02-29 | MedImmune, LLC | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
| AU2007272970C1 (en) | 2006-07-11 | 2013-01-10 | Roy C. Levitt | Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors |
| CA3177366A1 (en) | 2006-08-10 | 2008-02-21 | Roy C. Levitt | Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors |
| NZ577107A (en) | 2006-11-10 | 2012-01-12 | Cara Therapeutics Inc | Synthetic peptide amide ligands of the kappa opiod receptor |
| US8236766B2 (en) | 2006-11-10 | 2012-08-07 | Cara Therapeutics, Inc. | Uses of synthetic peptide amides |
| US7842662B2 (en) | 2006-11-10 | 2010-11-30 | Cara Therapeutics, Inc. | Synthetic peptide amide dimers |
| US8906859B2 (en) | 2006-11-10 | 2014-12-09 | Cera Therapeutics, Inc. | Uses of kappa opioid synthetic peptide amides |
| US7713937B2 (en) | 2006-11-10 | 2010-05-11 | Cara Therapeutics, Inc. | Synthetic peptide amides and dimeric forms thereof |
| EP2259768B1 (en) * | 2008-04-08 | 2019-05-22 | Merck Patent GmbH | Compositions containing cyclic peptides and methods of use |
| HUE033118T2 (hu) * | 2008-10-23 | 2017-11-28 | Steba Biotech S A | RGD-tartalmú peptidomimetikumok és ezek alkalmazásai |
| CN101906141B (zh) * | 2009-06-02 | 2013-04-17 | 首都医科大学 | 一类肽链与双脂肪醇链的偶联物及其制备方法和应用 |
| CN101906144B (zh) * | 2009-06-03 | 2013-06-19 | 首都医科大学 | 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用 |
| RU2626002C1 (ru) | 2016-10-24 | 2017-07-21 | Общество С Ограниченной Ответственностью "Айвикс" | Новая группа пептидов для лечения женской сексуальной дисфункции |
| RU2655763C2 (ru) * | 2016-10-24 | 2018-05-29 | Общество С Ограниченной Ответственностью "Айвикс" | Фармацевтическая композиция и способ лечения женских сексуальных дисфункций |
| US10494403B2 (en) | 2018-03-06 | 2019-12-03 | Ciphore Biomed Technology Limited Company | Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4472305A (en) * | 1983-05-17 | 1984-09-18 | Sterling Drug Inc. | Hexapeptide amides |
| JP2945680B2 (ja) * | 1988-09-09 | 1999-09-06 | 旭硝子株式会社 | ペプチド誘導体およびその用途 |
| US5192746A (en) * | 1990-07-09 | 1993-03-09 | Tanabe Seiyaku Co., Ltd. | Cyclic cell adhesion modulation compounds |
| JPH04264097A (ja) * | 1991-02-16 | 1992-09-18 | Asahi Glass Co Ltd | ペプチド誘導体およびその用途 |
| HUT63609A (en) * | 1992-03-10 | 1993-09-28 | Sandoz Ag | Process for producing new derivatives and isosters of beta-amino acids and pharmaceutical compositions comprising such compounds |
| UA43823C2 (uk) * | 1992-07-06 | 2002-01-15 | Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг | ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН |
| US5753230A (en) * | 1994-03-18 | 1998-05-19 | The Scripps Research Institute | Methods and compositions useful for inhibition of angiogenesis |
-
1993
- 1993-04-01 DE DE4310643A patent/DE4310643A1/de not_active Withdrawn
-
1994
- 1994-03-02 UA UA94005107A patent/UA34436C2/uk unknown
- 1994-03-21 DK DK94104396T patent/DK0632053T3/da active
- 1994-03-21 EP EP94104396A patent/EP0632053B1/de not_active Expired - Lifetime
- 1994-03-21 ES ES94104396T patent/ES2138632T3/es not_active Expired - Lifetime
- 1994-03-21 DE DE59408715T patent/DE59408715D1/de not_active Expired - Lifetime
- 1994-03-21 AT AT94104396T patent/ATE184288T1/de active
- 1994-03-25 CZ CZ1994704A patent/CZ286768B6/cs not_active IP Right Cessation
- 1994-03-29 NO NO19941152A patent/NO313756B1/no not_active IP Right Cessation
- 1994-03-30 CN CN94103298A patent/CN1056851C/zh not_active Expired - Lifetime
- 1994-03-30 TW TW083102761A patent/TW343198B/zh active
- 1994-03-30 CA CA002120303A patent/CA2120303C/en not_active Expired - Lifetime
- 1994-03-30 AU AU59185/94A patent/AU684489B2/en not_active Expired
- 1994-03-31 KR KR1019940006639A patent/KR100304201B1/ko not_active IP Right Cessation
- 1994-03-31 RU RU94011276A patent/RU2130030C1/ru active
- 1994-03-31 PL PL94302854A patent/PL178791B1/pl unknown
- 1994-03-31 JP JP09682994A patent/JP3694332B2/ja not_active Expired - Lifetime
- 1994-03-31 HU HU9400937A patent/HUT69726A/hu unknown
- 1994-03-31 SK SK383-94A patent/SK281828B6/sk unknown
-
1996
- 1996-03-15 US US08/616,770 patent/US5849692A/en not_active Expired - Lifetime
-
1998
- 1998-10-01 US US09/164,585 patent/US6169072B1/en not_active Expired - Lifetime
-
1999
- 1999-12-08 GR GR990403165T patent/GR3032074T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1056851C (zh) | 2000-09-27 |
| JP3694332B2 (ja) | 2005-09-14 |
| CA2120303A1 (en) | 1994-10-02 |
| RU2130030C1 (ru) | 1999-05-10 |
| CZ70494A3 (en) | 1995-01-18 |
| US5849692A (en) | 1998-12-15 |
| AU684489B2 (en) | 1997-12-18 |
| KR100304201B1 (ko) | 2001-11-30 |
| GR3032074T3 (en) | 2000-03-31 |
| UA34436C2 (uk) | 2001-03-15 |
| SK281828B6 (sk) | 2001-08-06 |
| EP0632053A2 (de) | 1995-01-04 |
| DE4310643A1 (de) | 1994-10-06 |
| HUT69726A (en) | 1995-09-28 |
| CN1099760A (zh) | 1995-03-08 |
| TW343198B (en) | 1998-10-21 |
| DE59408715D1 (de) | 1999-10-14 |
| HU9400937D0 (en) | 1994-06-28 |
| EP0632053B1 (de) | 1999-09-08 |
| PL178791B1 (pl) | 2000-06-30 |
| JPH06329698A (ja) | 1994-11-29 |
| CA2120303C (en) | 2007-05-01 |
| NO941152L (no) | 1994-10-03 |
| AU5918594A (en) | 1994-10-06 |
| CZ286768B6 (en) | 2000-07-12 |
| ATE184288T1 (de) | 1999-09-15 |
| DK0632053T3 (da) | 2000-03-13 |
| US6169072B1 (en) | 2001-01-02 |
| SK38394A3 (en) | 1995-02-08 |
| EP0632053A3 (de) | 1995-02-15 |
| ES2138632T3 (es) | 2000-01-16 |
| NO941152D0 (no) | 1994-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |