NO310866B1 - Kinolin-salthydrat som NK3-antagonist - Google Patents
Kinolin-salthydrat som NK3-antagonist Download PDFInfo
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- NO310866B1 NO310866B1 NO19982332A NO982332A NO310866B1 NO 310866 B1 NO310866 B1 NO 310866B1 NO 19982332 A NO19982332 A NO 19982332A NO 982332 A NO982332 A NO 982332A NO 310866 B1 NO310866 B1 NO 310866B1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9524137.8A GB9524137D0 (en) | 1995-11-24 | 1995-11-24 | Novel compounds |
| PCT/EP1996/005210 WO1997019928A1 (fr) | 1995-11-24 | 1996-11-22 | Sels de derives de quinoline en tant qu'antagonistes des neurokinines 3 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO982332L NO982332L (no) | 1998-05-22 |
| NO982332D0 NO982332D0 (no) | 1998-05-22 |
| NO310866B1 true NO310866B1 (no) | 2001-09-10 |
Family
ID=10784449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19982332A NO310866B1 (no) | 1995-11-24 | 1998-05-22 | Kinolin-salthydrat som NK3-antagonist |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US6355654B1 (fr) |
| EP (1) | EP0876348B1 (fr) |
| JP (1) | JP4377454B2 (fr) |
| KR (1) | KR19990071599A (fr) |
| CN (1) | CN1207728A (fr) |
| AR (1) | AR004970A1 (fr) |
| AT (1) | ATE233243T1 (fr) |
| AU (1) | AU722451B2 (fr) |
| BR (1) | BR9611729A (fr) |
| CA (1) | CA2238312A1 (fr) |
| CZ (1) | CZ158198A3 (fr) |
| DE (1) | DE69626416T2 (fr) |
| ES (1) | ES2192621T3 (fr) |
| GB (1) | GB9524137D0 (fr) |
| HU (1) | HUP9903584A3 (fr) |
| IL (1) | IL124352A0 (fr) |
| MX (1) | MX9804106A (fr) |
| NO (1) | NO310866B1 (fr) |
| NZ (1) | NZ323389A (fr) |
| PL (1) | PL326927A1 (fr) |
| TR (1) | TR199800925T2 (fr) |
| WO (1) | WO1997019928A1 (fr) |
| ZA (1) | ZA969812B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9825554D0 (en) | 1998-11-20 | 1999-01-13 | Smithkline Beecham Spa | Novel Compounds |
| US7037922B1 (en) | 2000-03-10 | 2006-05-02 | Neurogen Corporation | Aryl fused 2,4-disubstituted pyridines: NK3 receptor ligands |
| DE60004654T2 (de) | 1999-03-29 | 2004-06-24 | Neurogen Corp., Branford | 4-substituierte chinolinderivate als nk-3 und/oder gaba(a) rezeptor liganden |
| WO2000064877A1 (fr) * | 1999-04-26 | 2000-11-02 | Neurogen Corporation | 2-aminoquinolinecarboxamides: ligands de recepteurs de la neurokinine |
| JP2008542367A (ja) * | 2005-06-03 | 2008-11-27 | アストラゼネカ・アクチエボラーグ | Ｎｋ−３アンタゴニストとしてのキノリン誘導体 |
| GB0515580D0 (en) | 2005-07-29 | 2005-09-07 | Merck Sharp & Dohme | Therapeutic compounds |
| EP1919871A4 (fr) * | 2005-08-02 | 2010-08-18 | Glaxosmithkline Llc | Procédé pour la synthèse de dérivés de la quinoline |
| EP1915363A1 (fr) * | 2005-08-11 | 2008-04-30 | AstraZeneca AB | Modulateurs récépteurs nk3 en tant qu'amides de quinoléine oxopyridyl |
| US20080234269A1 (en) * | 2005-09-21 | 2008-09-25 | Astrazeneca Ab | N-Oxo-Heterocycle and N-Oxo-Alkyl Quinoline-4-Carboxamides as Nk-3 Receptor Ligands |
| AR057130A1 (es) * | 2005-09-21 | 2007-11-14 | Astrazeneca Ab | Quinolinas de alquilsulfoxido y una composicion farmaceutica |
| TW201018662A (en) | 2005-12-12 | 2010-05-16 | Astrazeneca Ab | Alkylsulphonamide quinolines |
| CN101410392A (zh) * | 2006-01-27 | 2009-04-15 | 阿斯利康(瑞典)有限公司 | 酰胺取代的喹啉类化合物 |
| FR2979173B1 (fr) * | 2011-08-19 | 2013-08-16 | St Microelectronics Grenoble 2 | Commutateur analogique basse tension |
| MY167423A (en) | 2011-11-03 | 2018-08-27 | Merck Sharp & Dohme | Quinoline carboxamide and quinoline carbonitrile derivatives as mglur2-negative allosteric modulators,compositions,and their use |
| US9475773B2 (en) | 2013-04-19 | 2016-10-25 | Astrazeneca Ab | NK3 receptor antagonist compound (NK3RA) for use in a method for the treatment of polycystic ovary syndrome (PCOS) |
| WO2017072629A1 (fr) | 2015-10-29 | 2017-05-04 | Cadila Healthcare Limited | Combinaison pharmaceutique d'antagoniste du récepteur nk3 et de biguanides |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT804419E (pt) * | 1994-05-27 | 2003-12-31 | Smithkline Beecham Farma | Derivados de quinolina como antagonistas do receptor de taquiquinina nk3 |
| IT1270615B (it) * | 1994-07-14 | 1997-05-07 | Smithkline Beecham Farma | Uso di derivati di chinolina |
-
1995
- 1995-11-24 GB GBGB9524137.8A patent/GB9524137D0/en active Pending
-
1996
- 1996-11-21 AR ARP960105281A patent/AR004970A1/es unknown
- 1996-11-22 IL IL12435296A patent/IL124352A0/xx unknown
- 1996-11-22 DE DE69626416T patent/DE69626416T2/de not_active Expired - Lifetime
- 1996-11-22 ES ES96941026T patent/ES2192621T3/es not_active Expired - Lifetime
- 1996-11-22 CA CA002238312A patent/CA2238312A1/fr not_active Abandoned
- 1996-11-22 AU AU10319/97A patent/AU722451B2/en not_active Ceased
- 1996-11-22 BR BR9611729A patent/BR9611729A/pt unknown
- 1996-11-22 JP JP52016097A patent/JP4377454B2/ja not_active Expired - Fee Related
- 1996-11-22 ZA ZA9609812A patent/ZA969812B/xx unknown
- 1996-11-22 US US09/077,152 patent/US6355654B1/en not_active Expired - Fee Related
- 1996-11-22 PL PL96326927A patent/PL326927A1/xx unknown
- 1996-11-22 CN CN96199611A patent/CN1207728A/zh active Pending
- 1996-11-22 HU HU9903584A patent/HUP9903584A3/hu unknown
- 1996-11-22 AT AT96941026T patent/ATE233243T1/de not_active IP Right Cessation
- 1996-11-22 WO PCT/EP1996/005210 patent/WO1997019928A1/fr not_active Application Discontinuation
- 1996-11-22 KR KR1019980703875A patent/KR19990071599A/ko not_active Application Discontinuation
- 1996-11-22 CZ CZ981581A patent/CZ158198A3/cs unknown
- 1996-11-22 EP EP96941026A patent/EP0876348B1/fr not_active Expired - Lifetime
- 1996-11-22 NZ NZ323389A patent/NZ323389A/en unknown
- 1996-11-22 TR TR1998/00925T patent/TR199800925T2/xx unknown
-
1998
- 1998-05-22 MX MX9804106A patent/MX9804106A/es unknown
- 1998-05-22 NO NO19982332A patent/NO310866B1/no not_active IP Right Cessation
-
2001
- 2001-11-06 US US09/994,076 patent/US6432977B1/en not_active Expired - Fee Related
-
2002
- 2002-06-12 US US10/167,881 patent/US20020156097A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000500770A (ja) | 2000-01-25 |
| US6432977B1 (en) | 2002-08-13 |
| IL124352A0 (en) | 1998-12-06 |
| BR9611729A (pt) | 1999-04-06 |
| JP4377454B2 (ja) | 2009-12-02 |
| NZ323389A (en) | 2000-02-28 |
| ATE233243T1 (de) | 2003-03-15 |
| WO1997019928A1 (fr) | 1997-06-05 |
| CA2238312A1 (fr) | 1997-06-05 |
| AU722451B2 (en) | 2000-08-03 |
| HUP9903584A3 (en) | 2001-10-29 |
| PL326927A1 (en) | 1998-11-09 |
| EP0876348B1 (fr) | 2003-02-26 |
| GB9524137D0 (en) | 1996-01-24 |
| CN1207728A (zh) | 1999-02-10 |
| DE69626416D1 (de) | 2003-04-03 |
| KR19990071599A (ko) | 1999-09-27 |
| AU1031997A (en) | 1997-06-19 |
| HUP9903584A2 (hu) | 2000-02-28 |
| AR004970A1 (es) | 1999-04-07 |
| US20020077335A1 (en) | 2002-06-20 |
| EP0876348A1 (fr) | 1998-11-11 |
| TR199800925T2 (xx) | 2001-05-21 |
| NO982332L (no) | 1998-05-22 |
| US20020156097A1 (en) | 2002-10-24 |
| CZ158198A3 (cs) | 1998-10-14 |
| ES2192621T3 (es) | 2003-10-16 |
| NO982332D0 (no) | 1998-05-22 |
| DE69626416T2 (de) | 2003-12-24 |
| US6355654B1 (en) | 2002-03-12 |
| MX9804106A (es) | 1998-09-30 |
| ZA969812B (en) | 1998-05-22 |
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