IL124352A0 - Salts of quinoline derivatives as nk3 antagonists - Google Patents
Salts of quinoline derivatives as nk3 antagonistsInfo
- Publication number
- IL124352A0 IL124352A0 IL12435296A IL12435296A IL124352A0 IL 124352 A0 IL124352 A0 IL 124352A0 IL 12435296 A IL12435296 A IL 12435296A IL 12435296 A IL12435296 A IL 12435296A IL 124352 A0 IL124352 A0 IL 124352A0
- Authority
- IL
- Israel
- Prior art keywords
- antagonists
- salts
- quinoline derivatives
- quinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9524137.8A GB9524137D0 (en) | 1995-11-24 | 1995-11-24 | Novel compounds |
PCT/EP1996/005210 WO1997019928A1 (fr) | 1995-11-24 | 1996-11-22 | Sels de derives de quinoline en tant qu'antagonistes des neurokinines 3 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL124352A0 true IL124352A0 (en) | 1998-12-06 |
Family
ID=10784449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12435296A IL124352A0 (en) | 1995-11-24 | 1996-11-22 | Salts of quinoline derivatives as nk3 antagonists |
Country Status (23)
Country | Link |
---|---|
US (3) | US6355654B1 (fr) |
EP (1) | EP0876348B1 (fr) |
JP (1) | JP4377454B2 (fr) |
KR (1) | KR19990071599A (fr) |
CN (1) | CN1207728A (fr) |
AR (1) | AR004970A1 (fr) |
AT (1) | ATE233243T1 (fr) |
AU (1) | AU722451B2 (fr) |
BR (1) | BR9611729A (fr) |
CA (1) | CA2238312A1 (fr) |
CZ (1) | CZ158198A3 (fr) |
DE (1) | DE69626416T2 (fr) |
ES (1) | ES2192621T3 (fr) |
GB (1) | GB9524137D0 (fr) |
HU (1) | HUP9903584A3 (fr) |
IL (1) | IL124352A0 (fr) |
MX (1) | MX9804106A (fr) |
NO (1) | NO310866B1 (fr) |
NZ (1) | NZ323389A (fr) |
PL (1) | PL326927A1 (fr) |
TR (1) | TR199800925T2 (fr) |
WO (1) | WO1997019928A1 (fr) |
ZA (1) | ZA969812B (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9825554D0 (en) * | 1998-11-20 | 1999-01-13 | Smithkline Beecham Spa | Novel Compounds |
US7037922B1 (en) | 2000-03-10 | 2006-05-02 | Neurogen Corporation | Aryl fused 2,4-disubstituted pyridines: NK3 receptor ligands |
US6413982B1 (en) | 1999-03-29 | 2002-07-02 | Neurogen Corporation | 4-substituted quinoline derivatives |
AU4802500A (en) | 1999-04-26 | 2000-11-10 | Neurogen Corporation | 2-aminoquinolinecarboxamides: neurokinin receptor ligands |
AU2006253054A1 (en) * | 2005-06-03 | 2006-12-07 | Astrazeneca Ab | Quinoline derivatives as NK3 anatgonists |
GB0515580D0 (en) | 2005-07-29 | 2005-09-07 | Merck Sharp & Dohme | Therapeutic compounds |
EP1919871A4 (fr) * | 2005-08-02 | 2010-08-18 | Glaxosmithkline Llc | Procédé pour la synthèse de dérivés de la quinoline |
JP2009504642A (ja) * | 2005-08-11 | 2009-02-05 | アストラゼネカ・アクチエボラーグ | Nk−3受容体の調節剤としてのオキソピリジルキノリンアミド |
WO2007035156A1 (fr) * | 2005-09-21 | 2007-03-29 | Astrazeneca Ab | Quinoline-4-carboxamides n-oxo-hétérocycliques et n-oxo-alkyliques en tant que ligands de récepteur nk-3 |
AR057130A1 (es) * | 2005-09-21 | 2007-11-14 | Astrazeneca Ab | Quinolinas de alquilsulfoxido y una composicion farmaceutica |
TW201018662A (en) | 2005-12-12 | 2010-05-16 | Astrazeneca Ab | Alkylsulphonamide quinolines |
EP1981882A4 (fr) * | 2006-01-27 | 2009-11-18 | Astrazeneca Ab | Quinoléines substituées par un amide |
FR2979173B1 (fr) * | 2011-08-19 | 2013-08-16 | St Microelectronics Grenoble 2 | Commutateur analogique basse tension |
US9278960B2 (en) | 2011-11-03 | 2016-03-08 | Merck Sharp & Dohme Corp. | Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use |
AU2014255512A1 (en) | 2013-04-19 | 2015-11-12 | Astrazeneca Ab | A NK3 receptor antagonist compound (NK3RA) for use in a method for the treatment of polycystic ovary syndrome (PCOS) |
WO2017072629A1 (fr) | 2015-10-29 | 2017-05-04 | Cadila Healthcare Limited | Combinaison pharmaceutique d'antagoniste du récepteur nk3 et de biguanides |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU226535B1 (en) | 1994-05-27 | 2009-03-30 | Glaxosmithkline Spa | Quinoline derivatives as tachykinin nk3 receptor antagonists, pharmaceutical compositions containing them, and their use |
IT1270615B (it) * | 1994-07-14 | 1997-05-07 | Smithkline Beecham Farma | Uso di derivati di chinolina |
-
1995
- 1995-11-24 GB GBGB9524137.8A patent/GB9524137D0/en active Pending
-
1996
- 1996-11-21 AR ARP960105281A patent/AR004970A1/es unknown
- 1996-11-22 AT AT96941026T patent/ATE233243T1/de not_active IP Right Cessation
- 1996-11-22 ZA ZA9609812A patent/ZA969812B/xx unknown
- 1996-11-22 WO PCT/EP1996/005210 patent/WO1997019928A1/fr not_active Application Discontinuation
- 1996-11-22 IL IL12435296A patent/IL124352A0/xx unknown
- 1996-11-22 BR BR9611729A patent/BR9611729A/pt unknown
- 1996-11-22 CA CA002238312A patent/CA2238312A1/fr not_active Abandoned
- 1996-11-22 CN CN96199611A patent/CN1207728A/zh active Pending
- 1996-11-22 HU HU9903584A patent/HUP9903584A3/hu unknown
- 1996-11-22 ES ES96941026T patent/ES2192621T3/es not_active Expired - Lifetime
- 1996-11-22 AU AU10319/97A patent/AU722451B2/en not_active Ceased
- 1996-11-22 TR TR1998/00925T patent/TR199800925T2/xx unknown
- 1996-11-22 JP JP52016097A patent/JP4377454B2/ja not_active Expired - Fee Related
- 1996-11-22 PL PL96326927A patent/PL326927A1/xx unknown
- 1996-11-22 US US09/077,152 patent/US6355654B1/en not_active Expired - Fee Related
- 1996-11-22 NZ NZ323389A patent/NZ323389A/en unknown
- 1996-11-22 DE DE69626416T patent/DE69626416T2/de not_active Expired - Lifetime
- 1996-11-22 KR KR1019980703875A patent/KR19990071599A/ko not_active Application Discontinuation
- 1996-11-22 EP EP96941026A patent/EP0876348B1/fr not_active Expired - Lifetime
- 1996-11-22 CZ CZ981581A patent/CZ158198A3/cs unknown
-
1998
- 1998-05-22 MX MX9804106A patent/MX9804106A/es unknown
- 1998-05-22 NO NO19982332A patent/NO310866B1/no not_active IP Right Cessation
-
2001
- 2001-11-06 US US09/994,076 patent/US6432977B1/en not_active Expired - Fee Related
-
2002
- 2002-06-12 US US10/167,881 patent/US20020156097A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU722451B2 (en) | 2000-08-03 |
CZ158198A3 (cs) | 1998-10-14 |
US20020077335A1 (en) | 2002-06-20 |
TR199800925T2 (xx) | 2001-05-21 |
WO1997019928A1 (fr) | 1997-06-05 |
MX9804106A (es) | 1998-09-30 |
GB9524137D0 (en) | 1996-01-24 |
HUP9903584A3 (en) | 2001-10-29 |
NO982332D0 (no) | 1998-05-22 |
JP4377454B2 (ja) | 2009-12-02 |
PL326927A1 (en) | 1998-11-09 |
CN1207728A (zh) | 1999-02-10 |
NO982332L (no) | 1998-05-22 |
EP0876348B1 (fr) | 2003-02-26 |
KR19990071599A (ko) | 1999-09-27 |
BR9611729A (pt) | 1999-04-06 |
CA2238312A1 (fr) | 1997-06-05 |
JP2000500770A (ja) | 2000-01-25 |
AR004970A1 (es) | 1999-04-07 |
ZA969812B (en) | 1998-05-22 |
US6355654B1 (en) | 2002-03-12 |
DE69626416T2 (de) | 2003-12-24 |
US6432977B1 (en) | 2002-08-13 |
DE69626416D1 (de) | 2003-04-03 |
ES2192621T3 (es) | 2003-10-16 |
NO310866B1 (no) | 2001-09-10 |
HUP9903584A2 (hu) | 2000-02-28 |
US20020156097A1 (en) | 2002-10-24 |
AU1031997A (en) | 1997-06-19 |
EP0876348A1 (fr) | 1998-11-11 |
NZ323389A (en) | 2000-02-28 |
ATE233243T1 (de) | 2003-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL317381A1 (en) | Derivatives of quinoline as antagonists of tachykynin receptors nk3 | |
CY2505B1 (en) | Quinoline derivatives as nk3 antagonists | |
IL124522A0 (en) | Quinoline derivatives | |
HUP9802940A2 (hu) | Kinolin-2(1H)-on-származékok mint szerotoninantagonisták | |
IL124352A0 (en) | Salts of quinoline derivatives as nk3 antagonists | |
GR3036346T3 (en) | BENZO[g]QUINOLINE DERIVATIVES | |
IL128141A0 (en) | Tetrahydroquinoline derivatives as eaa antagonists | |
PL326636A1 (en) | Derivatives of quinoline as inhibitors of type iv phosphodiesterase | |
PL333079A1 (en) | Piparazinic derivatives as antagonists of neurokinin | |
GB9404378D0 (en) | Quinoline derivatives | |
ZA954269B (en) | Quinoline derivatives | |
GB9402275D0 (en) | Quinoline derivatives | |
GB9413150D0 (en) | Quinoline derivatives | |
PL330723A1 (en) | Derivatives of benzo[g]quinoline | |
HU9900343D0 (en) | Use of quinoline derivatives having tachycinin nk3 receptor antagonist | |
PL318106A1 (en) | Quinoline derivatives as antagonists of leucotrienes | |
SI0940391T1 (en) | Quinoline derivatives as tachykinin NK3 receptor antagonists | |
IL126806A0 (en) | Quinoline derivatives | |
GB9413937D0 (en) | Quinoline derivatives | |
GB9402306D0 (en) | Quinoline derivatives | |
SI0839136T1 (en) | BENZO(g)QUINOLINE DERIVATIVES |