NO305209B1 - N-alkyl-2-substituerte ATP-analoger, slike forbindelser til fremstilling av terapeutikum, farmas°ytisk preparat inneholdende slike forbindelser, og deres anvendelse - Google Patents

N-alkyl-2-substituerte ATP-analoger, slike forbindelser til fremstilling av terapeutikum, farmas°ytisk preparat inneholdende slike forbindelser, og deres anvendelse

Info

Publication number
NO305209B1
NO305209B1 NO953126A NO953126A NO305209B1 NO 305209 B1 NO305209 B1 NO 305209B1 NO 953126 A NO953126 A NO 953126A NO 953126 A NO953126 A NO 953126A NO 305209 B1 NO305209 B1 NO 305209B1
Authority
NO
Norway
Prior art keywords
compounds
alkyl
therapeutics
preparation
pharmaceutical preparations
Prior art date
Application number
NO953126A
Other languages
English (en)
Norwegian (no)
Other versions
NO953126D0 (no
NO953126L (no
Inventor
Anthony Howard Ingall
Nicholas David Kindon
Peter Alan Cage
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939302636A external-priority patent/GB9302636D0/en
Priority claimed from GB939325712A external-priority patent/GB9325712D0/en
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of NO953126D0 publication Critical patent/NO953126D0/no
Publication of NO953126L publication Critical patent/NO953126L/no
Publication of NO305209B1 publication Critical patent/NO305209B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO953126A 1993-02-10 1995-08-09 N-alkyl-2-substituerte ATP-analoger, slike forbindelser til fremstilling av terapeutikum, farmas°ytisk preparat inneholdende slike forbindelser, og deres anvendelse NO305209B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939302636A GB9302636D0 (en) 1993-02-10 1993-02-10 Compounds
GB939325712A GB9325712D0 (en) 1993-12-16 1993-12-16 Compounds
PCT/GB1994/000237 WO1994018216A1 (en) 1993-02-10 1994-02-08 N-alkyl-2-substituted atp analogues

Publications (3)

Publication Number Publication Date
NO953126D0 NO953126D0 (no) 1995-08-09
NO953126L NO953126L (no) 1995-09-28
NO305209B1 true NO305209B1 (no) 1999-04-19

Family

ID=26302434

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953126A NO305209B1 (no) 1993-02-10 1995-08-09 N-alkyl-2-substituerte ATP-analoger, slike forbindelser til fremstilling av terapeutikum, farmas°ytisk preparat inneholdende slike forbindelser, og deres anvendelse

Country Status (26)

Country Link
US (2) US5721219A (cs)
EP (1) EP0683789B1 (cs)
JP (1) JP3083156B2 (cs)
KR (1) KR100315612B1 (cs)
CN (1) CN1042430C (cs)
AT (1) ATE159950T1 (cs)
AU (1) AU679721B2 (cs)
CA (1) CA2155673C (cs)
CZ (1) CZ286050B6 (cs)
DE (1) DE69406649T2 (cs)
DK (1) DK0683789T3 (cs)
ES (1) ES2108425T3 (cs)
FI (1) FI110687B (cs)
GR (1) GR3025995T3 (cs)
HK (1) HK1002936A1 (cs)
HU (1) HU221501B (cs)
IL (1) IL108602A (cs)
NO (1) NO305209B1 (cs)
NZ (1) NZ261159A (cs)
PL (1) PL175623B1 (cs)
RU (1) RU2136693C1 (cs)
SG (1) SG47943A1 (cs)
SK (1) SK281309B6 (cs)
TW (1) TW326045B (cs)
UA (1) UA54366C2 (cs)
WO (1) WO1994018216A1 (cs)

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US20120141468A1 (en) 2008-05-13 2012-06-07 Lisa Ruderman Chen Maintenance of platelet inhibition during antiplatelet therapy
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JP6577165B2 (ja) * 2011-01-26 2019-09-18 北京康倍得医▲藥▼技▲術▼▲開▼▲發▼有限公司 リボフラノシルプリン化合物、その調製方法、およびその使用
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CN107973798B (zh) * 2016-10-25 2020-04-24 上海医药工业研究院 2-[(3,3,3-三氟丙基)硫代]-6-氨基-9h-嘌呤及制法
CN107973832B (zh) * 2016-10-25 2021-11-12 上海医药工业研究院 6-n-[2-(甲硫基)乙基]-2-[(3，3，3-三氟丙基)硫代]腺苷的制法
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Also Published As

Publication number Publication date
KR100315612B1 (ko) 2002-06-20
HUT72464A (en) 1996-04-29
CN1042430C (zh) 1999-03-10
AU679721B2 (en) 1997-07-10
SK281309B6 (sk) 2001-02-12
WO1994018216A1 (en) 1994-08-18
HU221501B (en) 2002-10-28
GR3025995T3 (en) 1998-04-30
DE69406649T2 (de) 1998-03-05
CN1119869A (zh) 1996-04-03
DE69406649D1 (de) 1997-12-11
US5955447A (en) 1999-09-21
CA2155673C (en) 2004-08-17
ATE159950T1 (de) 1997-11-15
TW326045B (en) 1998-02-01
ES2108425T3 (es) 1997-12-16
NO953126D0 (no) 1995-08-09
SK99495A3 (en) 1996-02-07
PL310160A1 (en) 1995-11-27
JP3083156B2 (ja) 2000-09-04
CA2155673A1 (en) 1994-08-18
CZ286050B6 (cs) 1999-12-15
US5721219A (en) 1998-02-24
EP0683789B1 (en) 1997-11-05
PL175623B1 (pl) 1999-01-29
IL108602A (en) 1999-12-22
RU2136693C1 (ru) 1999-09-10
UA54366C2 (uk) 2003-03-17
FI953794L (fi) 1995-08-10
FI953794A0 (fi) 1995-08-10
JPH08506335A (ja) 1996-07-09
SG47943A1 (en) 1998-04-17
IL108602A0 (en) 1994-05-30
EP0683789A1 (en) 1995-11-29
FI110687B (fi) 2003-03-14
AU5977094A (en) 1994-08-29
NZ261159A (en) 1997-06-24
CZ203295A3 (en) 1995-12-13
NO953126L (no) 1995-09-28
DK0683789T3 (da) 1998-02-09
HK1002936A1 (en) 1998-09-25

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