NO301164B1 - Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse - Google Patents
Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse Download PDFInfo
- Publication number
- NO301164B1 NO301164B1 NO934758A NO934758A NO301164B1 NO 301164 B1 NO301164 B1 NO 301164B1 NO 934758 A NO934758 A NO 934758A NO 934758 A NO934758 A NO 934758A NO 301164 B1 NO301164 B1 NO 301164B1
- Authority
- NO
- Norway
- Prior art keywords
- phenyl
- tropane
- oxadiazol
- alkyl
- substituted
- Prior art date
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- 239000008194 pharmaceutical composition Substances 0.000 title description 2
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- -1 3, 4-methylenedioxyphenyl Chemical group 0.000 claims description 46
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 30
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- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- LATFBQGSWGHBGW-JRJWNBDDSA-N methyl (1R,2R,3S,5S)-8-methyl-3-phenylmethoxy-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride Chemical compound Cl.COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OCc1ccccc1)N2C LATFBQGSWGHBGW-JRJWNBDDSA-N 0.000 description 1
- AMIHUYQKNJHXPT-RBDSIQFVSA-N methyl (1s,3s,4r,5r)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(Cl)C(Cl)=C1 AMIHUYQKNJHXPT-RBDSIQFVSA-N 0.000 description 1
- QUSLQENMLDRCTO-GBJTYRQASA-N methyl (1s,3s,4r,5r)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(F)C=C1 QUSLQENMLDRCTO-GBJTYRQASA-N 0.000 description 1
- LCHVZQDOKNCPDQ-BSDSXHPESA-N methyl (1s,3s,4r,5r)-3-(4-tert-butylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(C(C)(C)C)C=C1 LCHVZQDOKNCPDQ-BSDSXHPESA-N 0.000 description 1
- MMKZDDDDODERSJ-ZJIFWQFVSA-N methyl (1s,3s,4r,5r)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(C)C=C1 MMKZDDDDODERSJ-ZJIFWQFVSA-N 0.000 description 1
- HGNMYGRBKGXPFK-DOIPELPJSA-N methyl (1s,3s,4r,5r)-8-methyl-3-(4-phenylphenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1=CC([C@@H]2[C@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C1C1=CC=CC=C1 HGNMYGRBKGXPFK-DOIPELPJSA-N 0.000 description 1
- RVCJYYIKKXDKHI-JEDBISTDSA-N methyl (1s,3s,4r,5r)-8-methyl-3-naphthalen-1-yl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1=CC=C2C([C@@H]3[C@H]([C@]4(CC[C@@](C3)(N4C)[H])[H])C(=O)OC)=CC=CC2=C1 RVCJYYIKKXDKHI-JEDBISTDSA-N 0.000 description 1
- ITFWLAOOLMWNLG-WJFTUGDTSA-N methyl (1s,3s,4r,5r)-8-methyl-3-naphthalen-2-yl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1=CC=CC2=CC([C@@H]3[C@H]([C@]4(CC[C@@](C3)(N4C)[H])[H])C(=O)OC)=CC=C21 ITFWLAOOLMWNLG-WJFTUGDTSA-N 0.000 description 1
- AMIHUYQKNJHXPT-DRABBMOASA-N methyl (1s,3s,4s,5r)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(Cl)C(Cl)=C1 AMIHUYQKNJHXPT-DRABBMOASA-N 0.000 description 1
- LCHVZQDOKNCPDQ-MLHJIOFPSA-N methyl (1s,3s,4s,5r)-3-(4-tert-butylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1([C@@H]2[C@@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C(C(C)(C)C)C=C1 LCHVZQDOKNCPDQ-MLHJIOFPSA-N 0.000 description 1
- HGNMYGRBKGXPFK-BQJUDKOJSA-N methyl (1s,3s,4s,5r)-8-methyl-3-(4-phenylphenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1=CC([C@@H]2[C@@H]([C@]3(CC[C@@](C2)(N3C)[H])[H])C(=O)OC)=CC=C1C1=CC=CC=C1 HGNMYGRBKGXPFK-BQJUDKOJSA-N 0.000 description 1
- ITFWLAOOLMWNLG-MANSERQUSA-N methyl (1s,3s,4s,5r)-8-methyl-3-naphthalen-2-yl-8-azabicyclo[3.2.1]octane-4-carboxylate Chemical compound C1=CC=CC2=CC([C@@H]3[C@@H]([C@]4(CC[C@@](C3)(N4C)[H])[H])C(=O)OC)=CC=C21 ITFWLAOOLMWNLG-MANSERQUSA-N 0.000 description 1
- RLLMNWXOZDXKCQ-AKMJYWSESA-N methyl (5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate hydrochloride Chemical compound Cl.COC(=O)C1C2CC[C@@H](CC1O)N2C RLLMNWXOZDXKCQ-AKMJYWSESA-N 0.000 description 1
- WXEMSGQRTGSYOG-PTNSZRNDSA-N methyl (5S)-8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylate Chemical compound C(=O)(OC)C1C2CC[C@@H](CC1=O)N2C WXEMSGQRTGSYOG-PTNSZRNDSA-N 0.000 description 1
- YDCHPLOFQATIDS-UHFFFAOYSA-N methyl 2-bromoacetate Chemical compound COC(=O)CBr YDCHPLOFQATIDS-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- AEXITZJSLGALNH-UHFFFAOYSA-N n'-hydroxyethanimidamide Chemical compound CC(N)=NO AEXITZJSLGALNH-UHFFFAOYSA-N 0.000 description 1
- KVBGVZZKJNLNJU-UHFFFAOYSA-N naphthalene-2-sulfonic acid Chemical compound C1=CC=CC2=CC(S(=O)(=O)O)=CC=C21 KVBGVZZKJNLNJU-UHFFFAOYSA-N 0.000 description 1
- 235000021096 natural sweeteners Nutrition 0.000 description 1
- 239000003176 neuroleptic agent Substances 0.000 description 1
- 210000001009 nucleus accumben Anatomy 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000006201 parenteral dosage form Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 235000010603 pastilles Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 description 1
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 230000001242 postsynaptic effect Effects 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N propylene glycol Substances CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 210000002637 putamen Anatomy 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- MMKZDDDDODERSJ-JJXSEGSLSA-N rti-32 Chemical compound C1([C@H]2C[C@@H]3CC[C@@H](N3C)[C@H]2C(=O)OC)=CC=C(C)C=C1 MMKZDDDDODERSJ-JJXSEGSLSA-N 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000005062 synaptic transmission Effects 0.000 description 1
- 210000003568 synaptosome Anatomy 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000007885 tablet disintegrant Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 150000003899 tartaric acid esters Chemical class 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
- 229940029284 trichlorofluoromethane Drugs 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- QQXLDOJGLXJCSE-KNVOCYPGSA-N tropinone Chemical compound C1C(=O)C[C@H]2CC[C@@H]1N2C QQXLDOJGLXJCSE-KNVOCYPGSA-N 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK921541A DK154192D0 (da) | 1992-12-23 | 1992-12-23 | Heterocycliske forbindelser |
| US08/093,183 US5369113A (en) | 1992-12-23 | 1993-07-16 | Certain 2,3-diphenyl-2-(1,2,4-oxadiazol-5-yl)tropanes useful as dopamide reuptake inhibitors |
| US08/093,181 US5444070A (en) | 1992-12-23 | 1993-07-16 | Phenyl substituted heterocyclic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO934758D0 NO934758D0 (no) | 1993-12-22 |
| NO934758L NO934758L (no) | 1994-06-24 |
| NO301164B1 true NO301164B1 (no) | 1997-09-22 |
Family
ID=27221329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO934758A NO301164B1 (no) | 1992-12-23 | 1993-12-22 | Alkylsubstituerte, heterosykliske forbindelser, anvendelser derav og farmasöytisk preparat som omfatter en slik forbindelse |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0604355B1 (fi) |
| JP (1) | JPH06293759A (fi) |
| AT (1) | ATE195314T1 (fi) |
| AU (1) | AU671163B2 (fi) |
| CA (1) | CA2112061C (fi) |
| DE (1) | DE69329184T2 (fi) |
| DK (1) | DK0604355T3 (fi) |
| ES (1) | ES2149193T3 (fi) |
| FI (1) | FI935798A (fi) |
| GR (1) | GR3034746T3 (fi) |
| NO (1) | NO301164B1 (fi) |
| NZ (1) | NZ250513A (fi) |
| PT (1) | PT604355E (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329520B1 (en) * | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
| AU672644B2 (en) * | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
| ATE222587T1 (de) * | 1994-04-19 | 2002-09-15 | Neurosearch As | TROPAN-2-ALDOXIMDERIVATE ALS NEUROTRANSMITTER ßREUPTAKEß INHIBITOREN |
| CN1056843C (zh) * | 1995-03-24 | 2000-09-27 | 纽罗研究公司 | 制备脱水芽子碱酯的方法 |
| CN1077574C (zh) | 1996-02-22 | 2002-01-09 | 神经研究公司 | 托烷衍生物,其制备和应用 |
| GB9915617D0 (en) * | 1999-07-05 | 1999-09-01 | Knoll Ag | Therapeutic agents |
| AU2002365288A1 (en) | 2001-11-30 | 2003-06-10 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| WO2005039580A1 (en) | 2003-10-16 | 2005-05-06 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor |
| EP1779851A1 (en) | 2005-10-31 | 2007-05-02 | Boehringer Ingelheim Pharma GmbH & Co.KG | Treatment of diabetes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3813404A (en) * | 1972-11-15 | 1974-05-28 | Sterling Drug Inc | Tropane-2-carboxylates and derivatives |
| FR2276823A1 (fr) * | 1974-07-04 | 1976-01-30 | Roussel Uclaf | Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits |
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
| NZ227684A (en) * | 1988-01-30 | 1991-07-26 | Merck Sharp & Dohme | Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions |
| ES2098248T3 (es) * | 1989-05-17 | 1997-05-01 | Pfizer | Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos. |
| DK198590D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DE69233656D1 (de) * | 1991-11-15 | 2006-10-19 | Res Triangle Inst | Kokain-Rezeptor Bindungsliganden |
| US5262428A (en) * | 1992-03-13 | 1993-11-16 | Wake Forest University | Biologically active tropane derivatives |
| US5268480A (en) * | 1992-09-22 | 1993-12-07 | Mayo Foundation For Medical Education And Research | Cocaine analogs |
-
1993
- 1993-12-13 AU AU52361/93A patent/AU671163B2/en not_active Ceased
- 1993-12-20 AT AT93610066T patent/ATE195314T1/de not_active IP Right Cessation
- 1993-12-20 DE DE69329184T patent/DE69329184T2/de not_active Expired - Lifetime
- 1993-12-20 EP EP93610066A patent/EP0604355B1/en not_active Expired - Lifetime
- 1993-12-20 ES ES93610066T patent/ES2149193T3/es not_active Expired - Lifetime
- 1993-12-20 PT PT93610066T patent/PT604355E/pt unknown
- 1993-12-20 NZ NZ250513A patent/NZ250513A/en unknown
- 1993-12-20 DK DK93610066T patent/DK0604355T3/da active
- 1993-12-21 CA CA002112061A patent/CA2112061C/en not_active Expired - Fee Related
- 1993-12-22 NO NO934758A patent/NO301164B1/no not_active IP Right Cessation
- 1993-12-22 JP JP5324472A patent/JPH06293759A/ja not_active Ceased
- 1993-12-22 FI FI935798A patent/FI935798A/fi unknown
-
2000
- 2000-11-02 GR GR20000402434T patent/GR3034746T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ250513A (en) | 1996-03-26 |
| AU5236193A (en) | 1994-07-07 |
| EP0604355B1 (en) | 2000-08-09 |
| AU671163B2 (en) | 1996-08-15 |
| EP0604355A3 (en) | 1995-02-08 |
| FI935798A0 (fi) | 1993-12-22 |
| JPH06293759A (ja) | 1994-10-21 |
| ATE195314T1 (de) | 2000-08-15 |
| ES2149193T3 (es) | 2000-11-01 |
| GR3034746T3 (en) | 2001-02-28 |
| DE69329184T2 (de) | 2001-04-05 |
| NO934758D0 (no) | 1993-12-22 |
| EP0604355A2 (en) | 1994-06-29 |
| DE69329184D1 (de) | 2000-09-14 |
| PT604355E (pt) | 2001-01-31 |
| CA2112061C (en) | 2002-11-19 |
| NO934758L (no) | 1994-06-24 |
| CA2112061A1 (en) | 1994-06-24 |
| DK0604355T3 (da) | 2000-12-04 |
| FI935798A (fi) | 1994-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JUNE 2003 |