DE69329184T2 - Alkylsubstituierte heterocyclische Verbindungen - Google Patents

Alkylsubstituierte heterocyclische Verbindungen

Info

Publication number
DE69329184T2
DE69329184T2 DE69329184T DE69329184T DE69329184T2 DE 69329184 T2 DE69329184 T2 DE 69329184T2 DE 69329184 T DE69329184 T DE 69329184T DE 69329184 T DE69329184 T DE 69329184T DE 69329184 T2 DE69329184 T2 DE 69329184T2
Authority
DE
Germany
Prior art keywords
alkyl substituted
substituted heterocyclic
heterocyclic compounds
compounds
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69329184T
Other languages
English (en)
Other versions
DE69329184D1 (de
Inventor
Peter Moldt
Jorgen Scheel-Krueger
Leif Helth Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK921541A external-priority patent/DK154192D0/da
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of DE69329184D1 publication Critical patent/DE69329184D1/de
Application granted granted Critical
Publication of DE69329184T2 publication Critical patent/DE69329184T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
DE69329184T 1992-12-23 1993-12-20 Alkylsubstituierte heterocyclische Verbindungen Expired - Lifetime DE69329184T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK921541A DK154192D0 (da) 1992-12-23 1992-12-23 Heterocycliske forbindelser
US08/093,183 US5369113A (en) 1992-12-23 1993-07-16 Certain 2,3-diphenyl-2-(1,2,4-oxadiazol-5-yl)tropanes useful as dopamide reuptake inhibitors
US08/093,181 US5444070A (en) 1992-12-23 1993-07-16 Phenyl substituted heterocyclic compounds

Publications (2)

Publication Number Publication Date
DE69329184D1 DE69329184D1 (de) 2000-09-14
DE69329184T2 true DE69329184T2 (de) 2001-04-05

Family

ID=27221329

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69329184T Expired - Lifetime DE69329184T2 (de) 1992-12-23 1993-12-20 Alkylsubstituierte heterocyclische Verbindungen

Country Status (13)

Country Link
EP (1) EP0604355B1 (de)
JP (1) JPH06293759A (de)
AT (1) ATE195314T1 (de)
AU (1) AU671163B2 (de)
CA (1) CA2112061C (de)
DE (1) DE69329184T2 (de)
DK (1) DK0604355T3 (de)
ES (1) ES2149193T3 (de)
FI (1) FI935798A (de)
GR (1) GR3034746T3 (de)
NO (1) NO301164B1 (de)
NZ (1) NZ250513A (de)
PT (1) PT604355E (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329520B1 (en) * 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
RU2134264C1 (ru) * 1994-04-19 1999-08-10 Нюросерч А/С Производные тропан-2-альдоксима, способ их получения, фармацевтическая композиция и вещества для производства лекарств на их основе и способ лечения растройства или болезни организма
JP3076373B2 (ja) * 1995-03-24 2000-08-14 ノイロサーチ アクティーゼルスカブ アンヒドロエクゴニンのエステル製造法
ZA971525B (en) * 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.
GB9915617D0 (en) * 1999-07-05 1999-09-01 Knoll Ag Therapeutic agents
US7381733B2 (en) 2001-11-30 2008-06-03 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
WO2005039580A1 (en) 2003-10-16 2005-05-06 Boehringer Ingelheim International Gmbh Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor
EP1779851A1 (de) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Behandlung von Diabetes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
FR2276823A1 (fr) * 1974-07-04 1976-01-30 Roussel Uclaf Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
ES2098248T3 (es) * 1989-05-17 1997-05-01 Pfizer Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos.
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
EP0644775B1 (de) * 1991-11-15 1999-08-04 Research Triangle Institute Kokainrezeptor bindende Liganden
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
US5268480A (en) * 1992-09-22 1993-12-07 Mayo Foundation For Medical Education And Research Cocaine analogs

Also Published As

Publication number Publication date
JPH06293759A (ja) 1994-10-21
EP0604355B1 (de) 2000-08-09
CA2112061A1 (en) 1994-06-24
AU671163B2 (en) 1996-08-15
CA2112061C (en) 2002-11-19
EP0604355A2 (de) 1994-06-29
ATE195314T1 (de) 2000-08-15
AU5236193A (en) 1994-07-07
NZ250513A (en) 1996-03-26
DE69329184D1 (de) 2000-09-14
GR3034746T3 (en) 2001-02-28
EP0604355A3 (de) 1995-02-08
DK0604355T3 (da) 2000-12-04
NO934758L (no) 1994-06-24
FI935798A (fi) 1994-06-24
PT604355E (pt) 2001-01-31
NO301164B1 (no) 1997-09-22
FI935798A0 (fi) 1993-12-22
ES2149193T3 (es) 2000-11-01
NO934758D0 (no) 1993-12-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition