NO2820016T3 - - Google Patents
Info
- Publication number
- NO2820016T3 NO2820016T3 NO13708603A NO13708603A NO2820016T3 NO 2820016 T3 NO2820016 T3 NO 2820016T3 NO 13708603 A NO13708603 A NO 13708603A NO 13708603 A NO13708603 A NO 13708603A NO 2820016 T3 NO2820016 T3 NO 2820016T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6847—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a hormone or a hormone-releasing or -inhibiting factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Crystallography & Structural Chemistry (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161490957P | 2011-05-27 | 2011-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2820016T3 true NO2820016T3 (fr) | 2017-12-30 |
Family
ID=47260229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO13708603A NO2820016T3 (fr) | 2011-05-27 | 2013-02-25 |
Country Status (20)
Country | Link |
---|---|
US (2) | US9545450B2 (fr) |
EP (1) | EP2714752B1 (fr) |
JP (2) | JP6300720B2 (fr) |
KR (2) | KR20190022943A (fr) |
CN (2) | CN104160033B (fr) |
BR (1) | BR112013030432A2 (fr) |
CA (1) | CA2836318C (fr) |
CY (1) | CY1120485T1 (fr) |
DK (1) | DK2714752T3 (fr) |
ES (1) | ES2660185T3 (fr) |
HR (1) | HRP20180291T1 (fr) |
HU (1) | HUE038172T2 (fr) |
LT (1) | LT2714752T (fr) |
NO (1) | NO2820016T3 (fr) |
PL (1) | PL2714752T3 (fr) |
PT (1) | PT2714752T (fr) |
RS (1) | RS56913B1 (fr) |
SI (1) | SI2714752T1 (fr) |
TR (1) | TR201802230T4 (fr) |
WO (1) | WO2012166653A2 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9925303B2 (en) * | 2012-11-13 | 2018-03-27 | Edwards Lifesciences Corporation | Methods for cross-linking bioprosthetic tissue using bio-orthogonal binding pairs |
ES2804594T3 (es) * | 2013-03-15 | 2021-02-08 | Amicus Therapeutics Inc | Reticuladores químicos |
KR102643502B1 (ko) * | 2014-04-04 | 2024-03-06 | 베스타론 코포레이션 | 인위적으로 활성화된 펩타이드 |
EA201790178A1 (ru) * | 2014-08-11 | 2017-07-31 | Шир Хьюман Дженетик Терапис, Инк. | Пептиды, несущие маннозо-6-фосфат, слитые с лизосомальным ферментом |
CA2961762C (fr) * | 2014-09-30 | 2024-03-05 | Amicus Therapeutics, Inc. | Alpha-glucosidase acide tres puissante ayant des hydrates de carbone ameliores |
CN104356238B (zh) * | 2014-10-15 | 2018-01-09 | 大连理工大学 | 一种重组蛋白a亲和配基的定点固定化方法 |
HUE045254T2 (hu) * | 2015-03-11 | 2019-12-30 | Ocv Intellectual Capital Llc | Eljárások kipufogódobok szálasanyaggal történõ megtöltésére |
CA3003750A1 (fr) | 2015-11-06 | 2017-05-11 | Biomarin Pharmaceutical Inc. | Dosage cellulaires pour la detection d'anticorps ou d'autres facteurs qui neutralisent l'absorption d'enzymes lysosomales |
EP3782639B1 (fr) * | 2015-12-08 | 2022-07-20 | Regeneron Pharmaceuticals, Inc. | Compositions et méthodes pour l'internalisation d'enzymes |
AU2018281280A1 (en) | 2017-06-07 | 2020-01-16 | Regeneron Pharmaceuticals, Inc. | Compositions and methods for internalizing enzymes |
CN110891592B (zh) | 2017-06-14 | 2024-08-13 | 维罗米蒂克斯股份公司 | 用于保护免受呼吸道合胞病毒的环状肽 |
TW201925236A (zh) | 2017-10-02 | 2019-07-01 | 美商戴納立製藥公司 | 包含酶替代療法酶之融合蛋白 |
US11492610B2 (en) | 2018-03-08 | 2022-11-08 | California Institute Of Technology | Sample multiplexing for single-cell RNA sequencing |
CN112513071A (zh) | 2018-04-30 | 2021-03-16 | 阿米库斯治疗学公司 | 基因治疗构建体和使用方法 |
WO2020077114A2 (fr) | 2018-10-10 | 2020-04-16 | Amicus Therapeutics, Inc. | Compositions de polypeptides stabilisées par une liaison disulfure et procédés d'utilisation |
CN113301925A (zh) | 2018-12-19 | 2021-08-24 | 小利兰·斯坦福大学理事会 | 用于溶酶体靶向的双官能分子以及相关的组合物和方法 |
JP2022514411A (ja) | 2018-12-20 | 2022-02-10 | ヴァイロメティックス アーゲー | リポペプチドビルディングブロックおよび合成ウイルス様粒子 |
EP3963063A4 (fr) * | 2019-04-30 | 2023-09-27 | The Trustees of The University of Pennsylvania | Compositions pour le traitement de la maladie de pompe |
CN110373405B (zh) * | 2019-07-24 | 2023-12-15 | 杭州恩和生物科技有限公司 | 一种接枝聚合物的生物酶及其制备方法和固定方法 |
KR20220077921A (ko) * | 2019-10-10 | 2022-06-09 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 변이체 igf2 작제물 |
US20230355737A1 (en) | 2020-09-28 | 2023-11-09 | Dbv Technologies | Particle comprising an rsv-f protein for use in rsv vaccination |
TW202237850A (zh) | 2020-12-01 | 2022-10-01 | 賓州大學委員會 | 具有組織特異性靶向基序的新穎構成物及含有其之組成物 |
EP4334334A1 (fr) | 2021-04-23 | 2024-03-13 | The Trustees of The University of Pennsylvania | Nouvelles compositions présentant des motifs de ciblage spécifiques au cerveau et compositions les contenant |
EP4359430A2 (fr) | 2021-06-23 | 2024-05-01 | Lycia Therapeutics, Inc. | Composés bifonctionnels contenant des polypeptides d'igf-2 |
WO2024130070A2 (fr) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Capsides aav recombinantes avec motifs de ciblage spécifiques du muscle cardiaque et squelettique et leurs utilisations |
WO2024130067A2 (fr) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Vecteurs mutants aav recombinants avec motifs de ciblage spécifiques des muscles cardiaque et squelettique et compositions les contenant |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1118334A1 (fr) * | 2000-01-11 | 2001-07-25 | Aventis Behring Gesellschaft mit beschränkter Haftung | Préparation de conjugués pour le traitement des allergies et maladies autoimmunitaires |
US7560424B2 (en) * | 2001-04-30 | 2009-07-14 | Zystor Therapeutics, Inc. | Targeted therapeutic proteins |
US20030072761A1 (en) * | 2001-10-16 | 2003-04-17 | Lebowitz Jonathan | Methods and compositions for targeting proteins across the blood brain barrier |
WO2005033134A2 (fr) | 2003-09-30 | 2005-04-14 | Regeneron Pharmaceuticals, Inc. | Therapeutique et utilisations d'une proteine secretee |
JP5627571B2 (ja) | 2008-05-07 | 2014-11-19 | バイオマリン ファーマシューティカル インコーポレイテッド | リソソーム標的化ペプチドおよびその使用 |
CN102448494B (zh) * | 2009-02-13 | 2016-02-03 | 免疫医疗公司 | 具有胞内可裂解的键的免疫共轭物 |
-
2012
- 2012-05-25 CA CA2836318A patent/CA2836318C/fr active Active
- 2012-05-25 JP JP2014513625A patent/JP6300720B2/ja active Active
- 2012-05-25 SI SI201231229T patent/SI2714752T1/en unknown
- 2012-05-25 DK DK12793015.4T patent/DK2714752T3/en active
- 2012-05-25 ES ES12793015.4T patent/ES2660185T3/es active Active
- 2012-05-25 TR TR2018/02230T patent/TR201802230T4/tr unknown
- 2012-05-25 BR BR112013030432A patent/BR112013030432A2/pt not_active Application Discontinuation
- 2012-05-25 EP EP12793015.4A patent/EP2714752B1/fr active Active
- 2012-05-25 HU HUE12793015A patent/HUE038172T2/hu unknown
- 2012-05-25 CN CN201280037051.0A patent/CN104160033B/zh active Active
- 2012-05-25 KR KR1020197005833A patent/KR20190022943A/ko not_active Application Discontinuation
- 2012-05-25 KR KR1020137034111A patent/KR101955054B1/ko active IP Right Grant
- 2012-05-25 US US14/122,858 patent/US9545450B2/en active Active
- 2012-05-25 PT PT127930154T patent/PT2714752T/pt unknown
- 2012-05-25 LT LTEP12793015.4T patent/LT2714752T/lt unknown
- 2012-05-25 WO PCT/US2012/039705 patent/WO2012166653A2/fr active Application Filing
- 2012-05-25 RS RS20180188A patent/RS56913B1/sr unknown
- 2012-05-25 CN CN201810440498.1A patent/CN108586621A/zh not_active Withdrawn
- 2012-05-25 PL PL12793015T patent/PL2714752T3/pl unknown
-
2013
- 2013-02-25 NO NO13708603A patent/NO2820016T3/no unknown
-
2016
- 2016-11-09 US US15/347,006 patent/US10660972B2/en active Active
-
2017
- 2017-07-07 JP JP2017133655A patent/JP2017225444A/ja active Pending
-
2018
- 2018-02-16 HR HRP20180291TT patent/HRP20180291T1/hr unknown
- 2018-02-22 CY CY20181100212T patent/CY1120485T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP2017225444A (ja) | 2017-12-28 |
CA2836318A1 (fr) | 2012-12-06 |
US20170319710A1 (en) | 2017-11-09 |
WO2012166653A3 (fr) | 2014-05-01 |
CN108586621A (zh) | 2018-09-28 |
US10660972B2 (en) | 2020-05-26 |
SI2714752T1 (en) | 2018-03-30 |
CN104160033B (zh) | 2018-06-01 |
US20140302001A1 (en) | 2014-10-09 |
EP2714752A4 (fr) | 2015-08-26 |
JP2014518063A (ja) | 2014-07-28 |
KR20190022943A (ko) | 2019-03-06 |
ES2660185T3 (es) | 2018-03-21 |
CY1120485T1 (el) | 2019-07-10 |
LT2714752T (lt) | 2018-03-12 |
TR201802230T4 (tr) | 2018-03-21 |
DK2714752T3 (en) | 2018-02-26 |
JP6300720B2 (ja) | 2018-03-28 |
KR20140033155A (ko) | 2014-03-17 |
HRP20180291T1 (hr) | 2018-03-23 |
US9545450B2 (en) | 2017-01-17 |
PT2714752T (pt) | 2018-02-26 |
EP2714752B1 (fr) | 2017-11-22 |
KR101955054B1 (ko) | 2019-03-07 |
RS56913B1 (sr) | 2018-05-31 |
HUE038172T2 (hu) | 2018-09-28 |
CA2836318C (fr) | 2018-11-27 |
CN104160033A (zh) | 2014-11-19 |
WO2012166653A2 (fr) | 2012-12-06 |
EP2714752A2 (fr) | 2014-04-09 |
BR112013030432A2 (pt) | 2016-12-13 |
PL2714752T3 (pl) | 2018-04-30 |