NO20092004L - 2-[L-fenyl-5-hydroksy-4-alfa-metyl-heksahydrosyklopenta[f]indazol-5-yl]etylfenylderivater som glukokortikoidreseptorligandere - Google Patents

2-[L-fenyl-5-hydroksy-4-alfa-metyl-heksahydrosyklopenta[f]indazol-5-yl]etylfenylderivater som glukokortikoidreseptorligandere

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Publication number
NO20092004L
NO20092004L NO20092004A NO20092004A NO20092004L NO 20092004 L NO20092004 L NO 20092004L NO 20092004 A NO20092004 A NO 20092004A NO 20092004 A NO20092004 A NO 20092004A NO 20092004 L NO20092004 L NO 20092004L
Authority
NO
Norway
Prior art keywords
phenyl
hexahydrocyclopenta
indazol
hydroxy
methyl
Prior art date
Application number
NO20092004A
Other languages
English (en)
Norwegian (no)
Inventor
James J Perkins
Christopher J Bungard
Jesse J Manikowski
Robert Meissner
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of NO20092004L publication Critical patent/NO20092004L/no

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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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    • A61K31/415—1,2-Diazoles
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NO20092004A 2006-10-23 2009-05-22 2-[L-fenyl-5-hydroksy-4-alfa-metyl-heksahydrosyklopenta[f]indazol-5-yl]etylfenylderivater som glukokortikoidreseptorligandere NO20092004L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85365506P 2006-10-23 2006-10-23
US92333707P 2007-04-13 2007-04-13
PCT/US2007/022449 WO2008060391A2 (en) 2006-10-23 2007-10-23 2- [l-phenyl-5-hydr0xy-4alpha-methyl-hexahydr0cycl0penta[f] indaz0l-5-yl] ethyl phenyl derivatives as glucocorticoid receptor ligands

Publications (1)

Publication Number Publication Date
NO20092004L true NO20092004L (no) 2009-07-22

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NO20092004A NO20092004L (no) 2006-10-23 2009-05-22 2-[L-fenyl-5-hydroksy-4-alfa-metyl-heksahydrosyklopenta[f]indazol-5-yl]etylfenylderivater som glukokortikoidreseptorligandere

Country Status (19)

Country Link
US (1) US8119681B2 (de)
EP (2) EP2097385B1 (de)
JP (1) JP5271911B2 (de)
KR (1) KR20090068345A (de)
CN (1) CN101528707B (de)
AT (1) ATE538099T1 (de)
AU (1) AU2007309507A1 (de)
BR (1) BRPI0718505A2 (de)
CA (1) CA2667007A1 (de)
CO (1) CO6190517A2 (de)
CR (1) CR10771A (de)
EA (1) EA200970401A1 (de)
IL (1) IL198226A0 (de)
MA (1) MA30870B1 (de)
MX (1) MX2009004385A (de)
NO (1) NO20092004L (de)
SV (1) SV2009003233A (de)
TN (1) TN2009000149A1 (de)
WO (2) WO2008060391A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
EP2211845B1 (de) * 2007-10-17 2017-02-22 Laboratoire HRA Pharma Glucocorticoid-rezeptor-antagonisten wie mifepriston zur behandlung des cushing-syndroms
US20100228036A1 (en) * 2007-10-23 2010-09-09 Qinghao Chen Process for making glucocorticoid receptor ligands
US8211930B2 (en) 2008-05-20 2012-07-03 Astrazeneca Ab Phenyl and benzodioxinyl substituted indazoles derivatives
WO2010138421A1 (en) * 2009-05-27 2010-12-02 Merck Sharp & Dohme Corp. HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
US20120095055A1 (en) 2009-06-02 2012-04-19 Merck Sharp & Dohme, Corp. HEXAHYDROCYCLOPENTYL[f]INDAZOLE 5-HYDROXYMETHYL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
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