CO6190517A2 - Derivados de 2-[1-fenil-5-hidroxi-4alfa-metil-hexahidrociclopenta [f]indazol-5-il]etil fenilo como ligandos del receptor glucocorticoide - Google Patents

Derivados de 2-[1-fenil-5-hidroxi-4alfa-metil-hexahidrociclopenta [f]indazol-5-il]etil fenilo como ligandos del receptor glucocorticoide

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Publication number
CO6190517A2
CO6190517A2 CO09040679A CO09040679A CO6190517A2 CO 6190517 A2 CO6190517 A2 CO 6190517A2 CO 09040679 A CO09040679 A CO 09040679A CO 09040679 A CO09040679 A CO 09040679A CO 6190517 A2 CO6190517 A2 CO 6190517A2
Authority
CO
Colombia
Prior art keywords
phenyl
indazol
methyl
derivatives
ethyl
Prior art date
Application number
CO09040679A
Other languages
English (en)
Inventor
Christopher Burgard
Jesse J Manikowski
James J Perkins
Robert S Meissner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CO6190517A2 publication Critical patent/CO6190517A2/es

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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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Abstract

Un compuesto seleccionado del siguiente grupo:...
CO09040679A 2006-10-23 2009-04-22 Derivados de 2-[1-fenil-5-hidroxi-4alfa-metil-hexahidrociclopenta [f]indazol-5-il]etil fenilo como ligandos del receptor glucocorticoide CO6190517A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85365506P 2006-10-23 2006-10-23
US92333707P 2007-04-13 2007-04-13

Publications (1)

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CO6190517A2 true CO6190517A2 (es) 2010-08-19

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CO09040679A CO6190517A2 (es) 2006-10-23 2009-04-22 Derivados de 2-[1-fenil-5-hidroxi-4alfa-metil-hexahidrociclopenta [f]indazol-5-il]etil fenilo como ligandos del receptor glucocorticoide

Country Status (19)

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US (1) US8119681B2 (es)
EP (2) EP2091922B1 (es)
JP (1) JP5271911B2 (es)
KR (1) KR20090068345A (es)
CN (1) CN101528707B (es)
AT (1) ATE538099T1 (es)
AU (1) AU2007309507A1 (es)
BR (1) BRPI0718505A2 (es)
CA (1) CA2667007A1 (es)
CO (1) CO6190517A2 (es)
CR (1) CR10771A (es)
EA (1) EA200970401A1 (es)
IL (1) IL198226A0 (es)
MA (1) MA30870B1 (es)
MX (1) MX2009004385A (es)
NO (1) NO20092004L (es)
SV (1) SV2009003233A (es)
TN (1) TN2009000149A1 (es)
WO (2) WO2008051532A1 (es)

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JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
EP2211845B1 (en) * 2007-10-17 2017-02-22 Laboratoire HRA Pharma Glucocorticoid receptor antagonists such as mifepristone for treating cushing's syndrome
EP2212294A1 (en) * 2007-10-23 2010-08-04 Merck Sharp & Dohme Corp. Process for making glucocorticoid receptor ligands
TWI445705B (zh) 2008-05-20 2014-07-21 Astrazeneca Ab 經苯基及苯并二基取代之吲唑衍生物
WO2010138421A1 (en) * 2009-05-27 2010-12-02 Merck Sharp & Dohme Corp. HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
US20120095055A1 (en) 2009-06-02 2012-04-19 Merck Sharp & Dohme, Corp. HEXAHYDROCYCLOPENTYL[f]INDAZOLE 5-HYDROXYMETHYL ETHANOLS AND DERIVATIVES THEREOF AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
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