SV2009003233A - Derivados de 2-(1-fenil -5- hidroxi -4alfa-metil-hexahidrociclopenta (f)indazol-5- il)etil fenilo como ligandos del receptor glucocorticoide - Google Patents

Derivados de 2-(1-fenil -5- hidroxi -4alfa-metil-hexahidrociclopenta (f)indazol-5- il)etil fenilo como ligandos del receptor glucocorticoide

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Publication number
SV2009003233A
SV2009003233A SV2009003233A SV2009003233A SV2009003233A SV 2009003233 A SV2009003233 A SV 2009003233A SV 2009003233 A SV2009003233 A SV 2009003233A SV 2009003233 A SV2009003233 A SV 2009003233A SV 2009003233 A SV2009003233 A SV 2009003233A
Authority
SV
El Salvador
Prior art keywords
phenyl
indazol
methyl
derivatives
ethyl
Prior art date
Application number
SV2009003233A
Other languages
English (en)
Inventor
Christopher J Bungard
Jesse J Manikowski
James J Perkins
Robert Meissner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SV2009003233A publication Critical patent/SV2009003233A/es

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Abstract

LA PRESENTE INVENCIÓN SE REFIERE A DERIVADOS DE 2-[L-FENIL-5-HIDROXI-4ALFA-METIL-HEXAHIDROCICLOPENTA[/]INDAZOL-5-IL]ETIL FENILO COMO LIGANDOS DEL RECEPTOR GLUCOCORTICOIDE ÚTILES PARA EL TRATAMIENTO DE UNA VARIEDAD DE ENFERMEDADES O AFECCIONES AUTOINMUNES E INFLAMATORIAS. TAMBIÉN SE INCLUYEN COMPOSICIONES FARMACÉUTICAS Y PROCEDIMIENTOS DE USO
SV2009003233A 2006-10-23 2009-04-21 Derivados de 2-(1-fenil -5- hidroxi -4alfa-metil-hexahidrociclopenta (f)indazol-5- il)etil fenilo como ligandos del receptor glucocorticoide SV2009003233A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85365506P 2006-10-23 2006-10-23
US92333707P 2007-04-13 2007-04-13

Publications (1)

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SV2009003233A true SV2009003233A (es) 2009-10-19

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US (1) US8119681B2 (es)
EP (2) EP2091922B1 (es)
JP (1) JP5271911B2 (es)
KR (1) KR20090068345A (es)
CN (1) CN101528707B (es)
AT (1) ATE538099T1 (es)
AU (1) AU2007309507A1 (es)
BR (1) BRPI0718505A2 (es)
CA (1) CA2667007A1 (es)
CO (1) CO6190517A2 (es)
CR (1) CR10771A (es)
EA (1) EA200970401A1 (es)
IL (1) IL198226A0 (es)
MA (1) MA30870B1 (es)
MX (1) MX2009004385A (es)
NO (1) NO20092004L (es)
SV (1) SV2009003233A (es)
TN (1) TN2009000149A1 (es)
WO (2) WO2008051532A1 (es)

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TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
EP2211845B1 (en) * 2007-10-17 2017-02-22 Laboratoire HRA Pharma Glucocorticoid receptor antagonists such as mifepristone for treating cushing's syndrome
AU2008317484A1 (en) * 2007-10-23 2009-04-30 Merck Sharp & Dohme Corp. Process for making glucocorticoid receptor ligands
TW200951114A (en) 2008-05-20 2009-12-16 Astrazeneca Ab Phenyl or pyridinyl substituted indazoles derivatives
WO2010138421A1 (en) * 2009-05-27 2010-12-02 Merck Sharp & Dohme Corp. HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
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