NO20085310L - Fremstilling av polymerkonjugater av terapeutiske, landbruks- og kosttillskuddsforbindelser - Google Patents

Fremstilling av polymerkonjugater av terapeutiske, landbruks- og kosttillskuddsforbindelser

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Publication number
NO20085310L
NO20085310L NO20085310A NO20085310A NO20085310L NO 20085310 L NO20085310 L NO 20085310L NO 20085310 A NO20085310 A NO 20085310A NO 20085310 A NO20085310 A NO 20085310A NO 20085310 L NO20085310 L NO 20085310L
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NO
Norway
Prior art keywords
agricultural
therapeutic
preparation
polymer conjugates
dietary compounds
Prior art date
Application number
NO20085310A
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English (en)
Inventor
Andrei W Konradi
Jenifer L Smith
Original Assignee
Elan Pharm Inc
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Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Publication of NO20085310L publication Critical patent/NO20085310L/no

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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Abstract

Foreliggende oppfinnelse tilveiebringer en forbedret syntese av polymerkonjugater med formel (I), av jordbruks-, terapeutiske og matadditiv forbindelser. Særlig er en fremgangsmåte beskrevet for fremstilling av konjugater ved behandling av primære eller sekundære alkoholsubstituenter til aktive forbindelser med polymere nukleofiler ved anvendelse av "Mitsunobu" eller relaterte reaksjonsbetingelser.
NO20085310A 2006-05-22 2008-12-18 Fremstilling av polymerkonjugater av terapeutiske, landbruks- og kosttillskuddsforbindelser NO20085310L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80234906P 2006-05-22 2006-05-22
PCT/US2007/069464 WO2007137260A2 (en) 2006-05-22 2007-05-22 Preparation of polymer conjugates of vla-4 antagonists via a mitsunobu' s reaction

Publications (1)

Publication Number Publication Date
NO20085310L true NO20085310L (no) 2009-02-13

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Application Number Title Priority Date Filing Date
NO20085310A NO20085310L (no) 2006-05-22 2008-12-18 Fremstilling av polymerkonjugater av terapeutiske, landbruks- og kosttillskuddsforbindelser

Country Status (15)

Country Link
US (1) US8138272B2 (no)
EP (1) EP2019690A2 (no)
JP (1) JP2009538338A (no)
KR (1) KR20090024166A (no)
CN (1) CN101495152A (no)
AU (1) AU2007253717A1 (no)
BR (1) BRPI0712013A2 (no)
CA (1) CA2651500A1 (no)
EA (1) EA015528B1 (no)
IL (1) IL195147A0 (no)
MX (1) MX2008014520A (no)
NO (1) NO20085310L (no)
SG (1) SG172604A1 (no)
TW (1) TW200817369A (no)
WO (1) WO2007137260A2 (no)

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US20080031848A1 (en) 2008-02-07
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WO2007137260A3 (en) 2008-06-26
US8138272B2 (en) 2012-03-20
JP2009538338A (ja) 2009-11-05
BRPI0712013A2 (pt) 2011-12-27
CA2651500A1 (en) 2007-11-29
MX2008014520A (es) 2008-11-27
EA200870561A1 (ru) 2009-06-30
WO2007137260A2 (en) 2007-11-29
EP2019690A2 (en) 2009-02-04
SG172604A1 (en) 2011-07-28
AU2007253717A1 (en) 2007-11-29
KR20090024166A (ko) 2009-03-06

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