NO20085000L - Salter og krystallmodifikasjoner derav - Google Patents

Salter og krystallmodifikasjoner derav

Info

Publication number
NO20085000L
NO20085000L NO20085000A NO20085000A NO20085000L NO 20085000 L NO20085000 L NO 20085000L NO 20085000 A NO20085000 A NO 20085000A NO 20085000 A NO20085000 A NO 20085000A NO 20085000 L NO20085000 L NO 20085000L
Authority
NO
Norway
Prior art keywords
salts
crystal modifications
phenyl
crystalline forms
crystal
Prior art date
Application number
NO20085000A
Other languages
English (en)
Inventor
Xinglong Jiang
Lili Feng
Piotr Karpinski
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20085000L publication Critical patent/NO20085000L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Oppfinnelsen er relatert til salter av 1-(2-fluor-fényl)-3-(2-okso-5-fényl-2,3-dihydro-11-1benzo[e][1,4]diazepin-3-yl)-urea og krystallinske former derav, deres produksjon og bruk, og farmasøytiske preparater inneholdende slike salter og krystallinske fonner.
NO20085000A 2006-05-23 2008-11-28 Salter og krystallmodifikasjoner derav NO20085000L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80283606P 2006-05-23 2006-05-23
PCT/US2007/069327 WO2007140154A2 (en) 2006-05-23 2007-05-21 Salts and crystal modifications thereof

Publications (1)

Publication Number Publication Date
NO20085000L true NO20085000L (no) 2008-12-23

Family

ID=38704747

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085000A NO20085000L (no) 2006-05-23 2008-11-28 Salter og krystallmodifikasjoner derav

Country Status (28)

Country Link
US (1) US7977330B2 (no)
EP (1) EP2029556B1 (no)
JP (2) JP2009538330A (no)
KR (1) KR20090009898A (no)
CN (1) CN101448796B (no)
AR (1) AR061056A1 (no)
AT (1) ATE486858T1 (no)
AU (1) AU2007267671A1 (no)
BR (1) BRPI0712556A2 (no)
CA (1) CA2650514A1 (no)
CL (1) CL2007001454A1 (no)
CR (1) CR10431A (no)
DE (1) DE602007010286D1 (no)
EC (1) ECSP088900A (no)
ES (1) ES2355166T3 (no)
GT (1) GT200800253A (no)
IL (1) IL195008A0 (no)
MA (1) MA30482B1 (no)
MX (1) MX2008014836A (no)
NO (1) NO20085000L (no)
PE (1) PE20080261A1 (no)
PL (1) PL2029556T3 (no)
PT (1) PT2029556E (no)
RU (1) RU2008150627A (no)
TN (1) TNSN08477A1 (no)
TW (1) TW200815375A (no)
WO (1) WO2007140154A2 (no)
ZA (1) ZA200809096B (no)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0314595A (pt) * 2002-09-20 2005-08-09 Arrow Therapeutics Ltd Uso de um derivado de benzodiazepina ou um sal farmaceuticamente aceitável deste, inalador ou nebulisador, produto, usos de um produto e de um composto ou sal farmaceuticamente aceitável deste, derivado de benzodiazepina, composto, e, composição farmacêutica

Also Published As

Publication number Publication date
ZA200809096B (en) 2009-11-25
ES2355166T3 (es) 2011-03-23
DE602007010286D1 (de) 2010-12-16
KR20090009898A (ko) 2009-01-23
BRPI0712556A2 (pt) 2013-07-02
CN101448796A (zh) 2009-06-03
TW200815375A (en) 2008-04-01
JP2009538330A (ja) 2009-11-05
CN101448796B (zh) 2012-09-26
IL195008A0 (en) 2009-08-03
MX2008014836A (es) 2008-12-01
US20090163478A1 (en) 2009-06-25
GT200800253A (es) 2009-04-29
CR10431A (es) 2009-01-07
ECSP088900A (es) 2008-12-30
MA30482B1 (fr) 2009-06-01
JP2013075910A (ja) 2013-04-25
ATE486858T1 (de) 2010-11-15
AR061056A1 (es) 2008-07-30
AU2007267671A1 (en) 2007-12-06
PT2029556E (pt) 2011-01-31
PL2029556T3 (pl) 2011-04-29
WO2007140154A2 (en) 2007-12-06
US7977330B2 (en) 2011-07-12
CL2007001454A1 (es) 2008-05-16
EP2029556A2 (en) 2009-03-04
WO2007140154A3 (en) 2008-03-20
PE20080261A1 (es) 2008-04-18
TNSN08477A1 (en) 2010-04-14
RU2008150627A (ru) 2010-06-27
EP2029556B1 (en) 2010-11-03
CA2650514A1 (en) 2007-12-06

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application