NO20084521L - Anti-IGF-IR antistoff og anvendelser derav - Google Patents
Anti-IGF-IR antistoff og anvendelser deravInfo
- Publication number
- NO20084521L NO20084521L NO20084521A NO20084521A NO20084521L NO 20084521 L NO20084521 L NO 20084521L NO 20084521 A NO20084521 A NO 20084521A NO 20084521 A NO20084521 A NO 20084521A NO 20084521 L NO20084521 L NO 20084521L
- Authority
- NO
- Norway
- Prior art keywords
- igf
- antibodies
- insulin
- fragments
- variants
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78634706P | 2006-03-28 | 2006-03-28 | |
US87655406P | 2006-12-22 | 2006-12-22 | |
PCT/US2007/007664 WO2007126876A2 (en) | 2006-03-28 | 2007-03-28 | Anti-igf-ir antibodies and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084521L true NO20084521L (no) | 2008-12-23 |
Family
ID=38656039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084521A NO20084521L (no) | 2006-03-28 | 2008-10-28 | Anti-IGF-IR antistoff og anvendelser derav |
Country Status (13)
Country | Link |
---|---|
US (3) | US7612178B2 (ko) |
EP (1) | EP1999149A4 (ko) |
JP (1) | JP2009532027A (ko) |
KR (1) | KR20080113268A (ko) |
AU (1) | AU2007245164A1 (ko) |
BR (1) | BRPI0709843A2 (ko) |
CA (1) | CA2646406A1 (ko) |
EA (1) | EA200802061A1 (ko) |
IL (1) | IL194266A0 (ko) |
MX (1) | MX2008012146A (ko) |
NO (1) | NO20084521L (ko) |
SG (1) | SG170799A1 (ko) |
WO (1) | WO2007126876A2 (ko) |
Families Citing this family (64)
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CN101842117A (zh) * | 2007-08-28 | 2010-09-22 | 比奥根艾迪克Ma公司 | 抗igf-1r抗体及其用途 |
CN106519025B (zh) | 2007-09-26 | 2021-04-23 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
EP2201378A2 (en) * | 2007-10-03 | 2010-06-30 | OSI Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors |
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AR069980A1 (es) * | 2007-12-26 | 2010-03-03 | Biotest Ag | Inmunoconjugados dirigidos contra cd 138 y sus usos |
WO2009120993A2 (en) * | 2008-03-28 | 2009-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Synthetic analogs of the juxtamembrane domain of igf1r and uses thereof |
CN102065895A (zh) * | 2008-04-11 | 2011-05-18 | 比奥根艾迪克Ma公司 | 抗-igf-1r抗体和其它化合物的治疗联合 |
PL2708558T3 (pl) | 2008-04-11 | 2018-09-28 | Chugai Seiyaku Kabushiki Kaisha | Cząsteczka wiążąca antygen zdolna do wiązania dwóch lub więcej cząsteczek antygenu w sposób powtarzalny |
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SG2014010573A (en) * | 2008-11-12 | 2014-04-28 | Merck Sharp & Dohme | ßGI-IGG INTRON FOR ENHANCED ANTI-IGF1 R EXPRESSION |
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JP6218746B2 (ja) | 2011-12-08 | 2017-10-25 | バイオテスト・アクチエンゲゼルシヤフト | Cd138を標的とする免疫複合体の使用 |
RU2014123030A (ru) * | 2011-12-22 | 2016-02-20 | Ринат Ньюросайенс Корп. | Антагонистические антитела против человеческого рецептора гормона роста и способы их применения |
EP2863947B1 (en) * | 2012-06-21 | 2018-03-07 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind igf1r |
KR20150036274A (ko) * | 2012-07-19 | 2015-04-07 | 알레시아 바이오쎄라퓨틱스 인코포레이티드 | 항-siglec-15 항체 |
US8980259B2 (en) | 2012-07-20 | 2015-03-17 | Novartis Ag | Combination therapy |
TW202340236A (zh) | 2012-08-24 | 2023-10-16 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
EP3597747B1 (en) | 2012-08-24 | 2023-03-15 | Chugai Seiyaku Kabushiki Kaisha | Mouse fcgammarii-specific fc antibody |
WO2014107165A1 (en) * | 2013-01-05 | 2014-07-10 | R-PHARM, CJSC (Closed Joint Stock Company) | Fully human antibodies against human receptor igf-1r |
US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
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SG11201706014PA (en) | 2015-02-05 | 2017-08-30 | Chugai Pharmaceutical Co Ltd | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof |
TWI740824B (zh) * | 2015-04-27 | 2021-10-01 | 法商皮爾法伯製藥公司 | 新穎的igf-1r抗體及其用於癌症診斷之用途(一) |
TWI716400B (zh) * | 2015-04-27 | 2021-01-21 | 法商皮爾法伯製藥公司 | 新穎的igf-1r抗體及其用於癌症診斷之用途(二) |
JP7141336B2 (ja) | 2015-12-25 | 2022-09-22 | 中外製薬株式会社 | 抗ミオスタチン抗体および使用方法 |
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CN112119090B (zh) | 2018-03-15 | 2023-01-13 | 中外制药株式会社 | 对寨卡病毒具有交叉反应性的抗登革热病毒抗体及使用方法 |
CA3119915A1 (en) * | 2018-12-03 | 2020-06-11 | Eric Steven BURAK | Radioimmunoconjugates and dna damage and repair inhibitor combination therapy |
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US7723483B2 (en) * | 2004-05-07 | 2010-05-25 | The University Of North Carolina At Chapel Hill | Method for enhancing or inhibiting insulin-like growth factor-I |
CA2576886A1 (en) * | 2004-08-12 | 2006-02-23 | Dyax Corp. | Tie complex binding proteins |
MY146381A (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
WO2006074399A2 (en) | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
US20090030187A1 (en) | 2005-03-14 | 2009-01-29 | Tous Guillermo I | Macromolecules comprising a thioether cross-link |
FR2888850B1 (fr) | 2005-07-22 | 2013-01-11 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
EP1999149A4 (en) | 2006-03-28 | 2010-01-20 | Biogen Idec Inc | ANTI-IGF-1R ANTIBODIES AND USES THEREOF |
WO2009032782A2 (en) | 2007-08-28 | 2009-03-12 | Biogen Idec Ma Inc. | Compositions that bind multiple epitopes of igf-1r |
CN101842117A (zh) * | 2007-08-28 | 2010-09-22 | 比奥根艾迪克Ma公司 | 抗igf-1r抗体及其用途 |
CN102065895A (zh) | 2008-04-11 | 2011-05-18 | 比奥根艾迪克Ma公司 | 抗-igf-1r抗体和其它化合物的治疗联合 |
-
2007
- 2007-03-28 EP EP07754217A patent/EP1999149A4/en not_active Withdrawn
- 2007-03-28 JP JP2009502971A patent/JP2009532027A/ja active Pending
- 2007-03-28 KR KR1020087026393A patent/KR20080113268A/ko not_active Application Discontinuation
- 2007-03-28 US US11/727,887 patent/US7612178B2/en active Active
- 2007-03-28 BR BRPI0709843-0A patent/BRPI0709843A2/pt not_active IP Right Cessation
- 2007-03-28 WO PCT/US2007/007664 patent/WO2007126876A2/en active Application Filing
- 2007-03-28 AU AU2007245164A patent/AU2007245164A1/en not_active Abandoned
- 2007-03-28 SG SG201102236-5A patent/SG170799A1/en unknown
- 2007-03-28 MX MX2008012146A patent/MX2008012146A/es active IP Right Grant
- 2007-03-28 EA EA200802061A patent/EA200802061A1/ru unknown
- 2007-03-28 CA CA002646406A patent/CA2646406A1/en not_active Abandoned
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2008
- 2008-09-22 IL IL194266A patent/IL194266A0/en unknown
- 2008-10-28 NO NO20084521A patent/NO20084521L/no not_active Application Discontinuation
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2009
- 2009-09-14 US US12/559,411 patent/US20100099147A1/en not_active Abandoned
- 2009-09-14 US US12/559,415 patent/US8147829B2/en not_active Expired - Fee Related
Also Published As
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US7612178B2 (en) | 2009-11-03 |
WO2007126876A2 (en) | 2007-11-08 |
WO2007126876A3 (en) | 2008-04-03 |
US20070243194A1 (en) | 2007-10-18 |
MX2008012146A (es) | 2008-10-03 |
KR20080113268A (ko) | 2008-12-29 |
CA2646406A1 (en) | 2007-11-08 |
US20100098710A1 (en) | 2010-04-22 |
SG170799A1 (en) | 2011-05-30 |
JP2009532027A (ja) | 2009-09-10 |
US20100099147A1 (en) | 2010-04-22 |
EA200802061A1 (ru) | 2009-04-28 |
BRPI0709843A2 (pt) | 2011-07-26 |
EP1999149A2 (en) | 2008-12-10 |
US8147829B2 (en) | 2012-04-03 |
IL194266A0 (en) | 2011-08-01 |
AU2007245164A1 (en) | 2007-11-08 |
EP1999149A4 (en) | 2010-01-20 |
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