ATE535546T1 - Humane monoklonale antikörper, die spezifisch an ifg-ii binden - Google Patents

Humane monoklonale antikörper, die spezifisch an ifg-ii binden

Info

Publication number
ATE535546T1
ATE535546T1 AT06789775T AT06789775T ATE535546T1 AT E535546 T1 ATE535546 T1 AT E535546T1 AT 06789775 T AT06789775 T AT 06789775T AT 06789775 T AT06789775 T AT 06789775T AT E535546 T1 ATE535546 T1 AT E535546T1
Authority
AT
Austria
Prior art keywords
antibodies
disclosed
nucleic acids
igf
ifg
Prior art date
Application number
AT06789775T
Other languages
English (en)
Inventor
Dimiter Dimitrov
Yang Feng
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE535546T1 publication Critical patent/ATE535546T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT06789775T 2005-08-17 2006-08-15 Humane monoklonale antikörper, die spezifisch an ifg-ii binden ATE535546T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70922605P 2005-08-17 2005-08-17
US79881706P 2006-05-08 2006-05-08
PCT/US2006/031814 WO2007022172A1 (en) 2005-08-17 2006-08-15 Human monoclonal antibodies that specifically bind igf-ii

Publications (1)

Publication Number Publication Date
ATE535546T1 true ATE535546T1 (de) 2011-12-15

Family

ID=37564252

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06789775T ATE535546T1 (de) 2005-08-17 2006-08-15 Humane monoklonale antikörper, die spezifisch an ifg-ii binden

Country Status (7)

Country Link
US (1) US8105598B2 (de)
EP (1) EP1924604B1 (de)
JP (1) JP5149800B2 (de)
AT (1) ATE535546T1 (de)
AU (1) AU2006279633B2 (de)
CA (1) CA2618920C (de)
WO (1) WO2007022172A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004289953B2 (en) 2003-06-18 2008-09-25 Genelux Corporation Modified recombinant vaccina viruses and other microorganisms, uses thereof
RU2492185C2 (ru) 2005-12-13 2013-09-10 Астразенека Аб Связывающие протеины, специфичные по отношению к инсулин-подобным факторам роста, и их использование
JP5734180B2 (ja) * 2008-05-09 2015-06-17 ダイアックス コーポレーション Ｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質
EP2349329A4 (de) * 2008-10-14 2012-10-31 Dyax Corp Verwendung von igf-ii/igf-iie-bindung zur behandlung und prävention von systemischer sklerose im zusammenhang mit lungenfibrose
CZ2008697A3 (cs) * 2008-11-03 2010-04-28 Univerzita Karlova v Praze, 1. Lékarská fakulta Kombinace monoklonálních protilátek nebo jejich Fab fragmentu pro použití jako lécivo a farmaceutický prípravek tyto protilátky nebo jejich Fab fragmenty obsahující
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
US9127056B2 (en) 2011-10-17 2015-09-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II)
WO2013119419A1 (en) 2012-02-08 2013-08-15 North Carolina State University Treatment of allergic diseases with recombinant antibodies
CN106519024A (zh) * 2015-09-15 2017-03-22 三生国健药业（上海）股份有限公司 一种用于去除单克隆抗体中异构体的复性液及复性方法
EP3538558A4 (de) 2016-11-09 2020-07-15 North Carolina State University Behandlung allergischer erkrankungen mit einem chimären protein
WO2019183437A1 (en) 2018-03-23 2019-09-26 North Carolina State University Methods and compositions for antibody to high affinity receptor for ige

Also Published As

Publication number Publication date
EP1924604A1 (de) 2008-05-28
WO2007022172A1 (en) 2007-02-22
EP1924604B1 (de) 2011-11-30
JP5149800B2 (ja) 2013-02-20
AU2006279633A1 (en) 2007-02-22
AU2006279633B2 (en) 2011-03-03
CA2618920C (en) 2015-03-24
US20110008358A1 (en) 2011-01-13
US8105598B2 (en) 2012-01-31
CA2618920A1 (en) 2007-02-22
JP2009507471A (ja) 2009-02-26

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