NO20082986L - Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser - Google Patents

Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser

Info

Publication number
NO20082986L
NO20082986L NO20082986A NO20082986A NO20082986L NO 20082986 L NO20082986 L NO 20082986L NO 20082986 A NO20082986 A NO 20082986A NO 20082986 A NO20082986 A NO 20082986A NO 20082986 L NO20082986 L NO 20082986L
Authority
NO
Norway
Prior art keywords
treatment
acyl
novel
cardiovascular disorders
furopyrimidine derivatives
Prior art date
Application number
NO20082986A
Other languages
English (en)
Norwegian (no)
Inventor
Andreas Knorr
Johannes-Peter Stasch
Rudolf Schohe-Loop
Karl-Heinz Schlemmer
Mario Jeske
Lars Barfacker
Thomas Lampe
Eva-Maria Becker
Raimund Kast
Hartmut Beck
Joachim Schuhmacher
Friederike Stoll
Martina Klein
Metin Akbaba
Alexander Hillisch
Gunter Karig
Mark Meininghaus
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of NO20082986L publication Critical patent/NO20082986L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
NO20082986A 2005-12-21 2008-07-02 Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser NO20082986L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005061170A DE102005061170A1 (de) 2005-12-21 2005-12-21 Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung
PCT/EP2006/011826 WO2007079862A1 (de) 2005-12-21 2006-12-08 Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen

Publications (1)

Publication Number Publication Date
NO20082986L true NO20082986L (no) 2008-07-02

Family

ID=37876878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082986A NO20082986L (no) 2005-12-21 2008-07-02 Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser

Country Status (32)

Country Link
US (1) US8183246B2 (uk)
EP (1) EP1966217B1 (uk)
JP (1) JP5254032B2 (uk)
KR (1) KR101429777B1 (uk)
CN (1) CN101384603B (uk)
AR (1) AR058108A1 (uk)
AU (1) AU2006334856B2 (uk)
BR (1) BRPI0620317A2 (uk)
CA (1) CA2633701C (uk)
CR (1) CR10092A (uk)
DE (1) DE102005061170A1 (uk)
DK (1) DK1966217T3 (uk)
DO (1) DOP2006000280A (uk)
EC (1) ECSP088569A (uk)
ES (1) ES2418855T3 (uk)
GT (1) GT200800117A (uk)
HK (1) HK1130054A1 (uk)
IL (1) IL192062A0 (uk)
MA (1) MA30039B1 (uk)
NO (1) NO20082986L (uk)
NZ (1) NZ569214A (uk)
PE (1) PE20071168A1 (uk)
PL (1) PL1966217T3 (uk)
PT (1) PT1966217E (uk)
RU (1) RU2454419C2 (uk)
SV (1) SV2009002953A (uk)
TN (1) TNSN08279A1 (uk)
TW (1) TWI405764B (uk)
UA (1) UA94080C2 (uk)
UY (1) UY30046A1 (uk)
WO (1) WO2007079862A1 (uk)
ZA (1) ZA200805385B (uk)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007019691A1 (de) * 2007-04-26 2008-10-30 Bayer Healthcare Ag Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie
DE102007027799A1 (de) * 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte Furopyrimidine und ihre Verwendung
DE102007051762A1 (de) * 2007-10-30 2009-05-07 Bayer Healthcare Ag Substituierte Pyrrolotriazine und ihre Verwendung
DE102007054786A1 (de) * 2007-11-16 2009-05-20 Bayer Healthcare Ag Trisubstituierte Furopyrimidine und ihre Verwendung
EP2848621A4 (en) 2012-05-10 2016-06-01 Takeda Pharmaceutical AROMATIC CYCLIC COMPOUND
EP2848622A4 (en) 2012-05-10 2015-11-04 Takeda Pharmaceutical AROMATIC RING CONNECTION
JP7254078B2 (ja) 2017-11-27 2023-04-07 ダート・ニューロサイエンス・エルエルシー Pde1阻害剤としての置換フラノピリミジン化合物
KR20220007889A (ko) * 2019-05-13 2022-01-19 릴레이 테라퓨틱스, 인크. Fgfr 저해제 및 이의 사용 방법
KR102094337B1 (ko) 2019-10-01 2020-03-27 안문호 금속이물질 제거장치

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577420A (en) 1968-01-05 1971-05-04 Pfizer Certain 4-aminofuro(2,3-d)pyrimidines
EP1018514B1 (en) 1998-07-22 2004-05-12 Daiichi Suntory Pharma Co., Ltd. NF-$g(k)B INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT
EP1181296A1 (en) 1999-06-03 2002-02-27 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
CA2350992C (en) 1999-09-17 2009-06-23 Suntory Limited Preventive or therapeutic agents for myocarditis, dilated cardiomyopathy and heart failure comprising nf-kb inhibitors as active ingredients
CA2449188A1 (en) 2001-05-14 2002-11-21 Novartis Ag Oxazolo-and furopyrimidines and their use in medicaments against tumors
DE10141212A1 (de) 2001-08-22 2003-03-06 Bayer Ag Neue 4-Aminofuropyrimidine und ihre Verwendung
US7427623B2 (en) 2001-09-11 2008-09-23 Smithkline Beecham Corporation 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
US20030225098A1 (en) * 2002-03-21 2003-12-04 Hirst Gavin C. Kinase inhibitors
KR20050091462A (ko) * 2004-03-12 2005-09-15 한국과학기술연구원 푸로피리미딘 화합물 및 이를 포함하는 ddr2 티로신키나아제 활성 저해제
WO2005121149A1 (en) 2004-06-10 2005-12-22 Xention Discovery Limited Furanopyrimidine compounds effective as potassium channel inhibitors
JP2008505084A (ja) 2004-06-29 2008-02-21 アムゲン インコーポレイティッド フラノピリミジン

Also Published As

Publication number Publication date
CA2633701C (en) 2014-05-27
NZ569214A (en) 2011-07-29
IL192062A0 (en) 2008-12-29
SV2009002953A (es) 2009-04-28
US20090318475A1 (en) 2009-12-24
HK1130054A1 (en) 2009-12-18
ECSP088569A (es) 2008-08-29
PL1966217T3 (pl) 2013-09-30
US8183246B2 (en) 2012-05-22
JP2009520713A (ja) 2009-05-28
ZA200805385B (en) 2009-10-28
DOP2006000280A (es) 2007-07-31
ES2418855T3 (es) 2013-08-16
CN101384603B (zh) 2012-08-01
WO2007079862A1 (de) 2007-07-19
PE20071168A1 (es) 2008-02-07
AR058108A1 (es) 2008-01-23
JP5254032B2 (ja) 2013-08-07
EP1966217A1 (de) 2008-09-10
UY30046A1 (es) 2007-07-31
RU2454419C2 (ru) 2012-06-27
RU2008129363A (ru) 2010-01-27
EP1966217B1 (de) 2013-05-08
DE102005061170A1 (de) 2007-07-05
TW200745132A (en) 2007-12-16
GT200800117A (es) 2009-12-16
AU2006334856B2 (en) 2013-04-04
AU2006334856A1 (en) 2007-07-19
PT1966217E (pt) 2013-07-12
TWI405764B (zh) 2013-08-21
CR10092A (es) 2008-10-08
KR101429777B1 (ko) 2014-08-19
TNSN08279A1 (en) 2009-10-30
CA2633701A1 (en) 2007-07-19
CN101384603A (zh) 2009-03-11
KR20080081323A (ko) 2008-09-09
DK1966217T3 (da) 2013-08-05
MA30039B1 (fr) 2008-12-01
UA94080C2 (uk) 2011-04-11
BRPI0620317A2 (pt) 2011-11-08

Similar Documents

Publication Publication Date Title
NO20082986L (no) Nye, acylisk substituerte furopyrimidinderivater og anvendelse derav for behandling av kardiovaskulaere lidelser
CY1112813T1 (el) 4-(4-κυανο-2-θειοαρυλ)διϋδροπυριμιδινονες και η χρηση αυτων
ATE453642T1 (de) Substituierte phenylaminopyrimidine
ATE416177T1 (de) Hetaryloxy-substituierte phenylaminopyrimidine als rho-kinasehemmer
NO20051726L (no) Pyrimidinonderivaer som terapeutiske midler ovenfor akutte og kroniske inflammasjons-, iskemiske og remodeleringsprosesser
MX2007002470A (es) Fenilaminotiazoles sustituidos y su uso.
NO20050579L (no) Indolinfenylsulfonamidderivater
MX2011009539A (es) 2-acetamido-5-aril-1,2,4-triazolonas sustituidas y su uso.
NO20081878L (no) Diacylindazolderivater som lipase- og fosfolipaseinhibitorer
NO20085338L (no) Substituerte 1,3-difenylpropanderivater, sammensetninger og anvendelser derav
ATE481088T1 (de) Embolisierung unter verwendung von poly-4- hydroxybutyrat-partikeln
NO20073574L (no) Triazolsubstituerte aminobenzofenonforbindelser
UY31305A1 (es) Derivados de 1,2,4,5-tetrahidro-3h-benzazepinas, su procedimiento de preparacion y las composiciones farmacéuticas que las contienen.
NO20072051L (no) Nye pyrimidinderivater og deres anvendelse som PPAR-alfa modulatorar
PA8583601A1 (es) Derivados de pirrolidona como inhibidores de maob
ECSP11011482A (es) Piperidinas sustituidas
NO20074780L (no) Heterocyklylamidsubstituerte imidazoler
ATE433459T1 (de) Desoxo-nonadepsipeptide
DE602004017326D1 (de) Tetrahydrocarbazolderivate und deren pharmazeutische verwendung
NO20076405L (no) Anvendelse av 24-nor-UDCA
ATE455789T1 (de) Substituierte nonadepsipeptide
ATE524463T1 (de) 4-chromenonyl-1,4-dihydropyridincarbonitrile und ihre verwendung
DE502005005652D1 (de) Heterocyclyl-substituierte nonadepsipeptide
ATE527256T1 (de) Substituierte (oxazolidinon-5-yl-methyl) -2- thiophen-carboxamide und ihre verwendung im gebiet der blutgerinnung
ATE496047T1 (de) Phenylen-bis-oxazolidin-derivate und ihre verwendung als antikoagulantien

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

FC2A Withdrawal, rejection or dismissal of laid open patent application