NO20076344L - Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptoren - Google Patents
Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptorenInfo
- Publication number
- NO20076344L NO20076344L NO20076344A NO20076344A NO20076344L NO 20076344 L NO20076344 L NO 20076344L NO 20076344 A NO20076344 A NO 20076344A NO 20076344 A NO20076344 A NO 20076344A NO 20076344 L NO20076344 L NO 20076344L
- Authority
- NO
- Norway
- Prior art keywords
- agonists
- piperazine
- ht1a receptor
- compounds
- ht1a
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår nye piperazin-piperidin-forbindelser. Forbindelsene er anvendelige som 5-HT1A bindemidler, spesielt som 5-HT1A reseptorantagonister og -agonister. Disse forbindelser er anvendelige for behandling av sentralnervesystem-lidelser, så som kognisjons-lidelser, angst-lidelser, depresjon og seksuell dysfunksjon.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68946905P | 2005-06-10 | 2005-06-10 | |
PCT/US2006/022719 WO2006135839A2 (en) | 2005-06-10 | 2006-06-09 | Piperazine-piperidine antagonists and agonists of the 5-ht1a receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20076344L true NO20076344L (no) | 2008-02-27 |
Family
ID=37530084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076344A NO20076344L (no) | 2005-06-10 | 2007-12-11 | Piperazin-piperidin-antagonister og agonister av 5-HT1A-reseptoren |
Country Status (20)
Country | Link |
---|---|
US (1) | US7671056B2 (no) |
EP (1) | EP1888559A2 (no) |
JP (1) | JP2008543782A (no) |
KR (1) | KR20080021134A (no) |
CN (1) | CN101243073A (no) |
AR (1) | AR055059A1 (no) |
AU (1) | AU2006257874A1 (no) |
BR (1) | BRPI0613491A2 (no) |
CA (1) | CA2611711A1 (no) |
CR (1) | CR9560A (no) |
EC (1) | ECSP088094A (no) |
GT (1) | GT200600255A (no) |
IL (1) | IL187972A0 (no) |
MX (1) | MX2007015678A (no) |
NO (1) | NO20076344L (no) |
PE (1) | PE20070069A1 (no) |
RU (1) | RU2007146543A (no) |
TW (1) | TW200800959A (no) |
WO (1) | WO2006135839A2 (no) |
ZA (1) | ZA200710699B (no) |
Families Citing this family (15)
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TW200800959A (en) | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
TW200808740A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
TW200808730A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Process for synthesizing piperazine-piperidine compounds |
TW200808741A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
CA2649576A1 (en) * | 2006-06-09 | 2007-12-21 | Wyeth | Method for enhancing cognitive function |
TW200811144A (en) * | 2006-06-09 | 2008-03-01 | Wyeth Corp | Crystalline forms of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline |
CL2007003409A1 (es) * | 2006-11-28 | 2008-04-11 | Wyeth Corp | Perla de liberacion controlada que comprende una unidad de nucleo central, una primera capa con un agente farmacologico que es un compuesto derivado de piperazina-piperidina, un acidificante, una segunda capa; procedimiento de preparacion; formulacio |
CL2007003410A1 (es) * | 2006-11-28 | 2008-04-11 | Wyeth Corp | Compuestos derivados de 5-fluoro-8-{4-[4-(6-metoxiquinolin-8-il)piperazin-1-il]piperidin-1-il}quinolina; procedimiento de preparacion; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de trast |
WO2008101139A1 (en) * | 2007-02-16 | 2008-08-21 | Wyeth | Sustained-release tablet formulations of piperazine-piperidine antagonists and agonists of the 5-ht1a receptor having enhanced intestinal dissolution |
WO2010033045A1 (en) * | 2008-09-16 | 2010-03-25 | Igor Anatolievich Pomytkin | Compositions and methods for prevention or treatment of beta amyloid deposition |
WO2010081851A1 (en) | 2009-01-14 | 2010-07-22 | Genoscience Pharma | Piperidin-4-ylpiperazine compounds for the treatment of hcv infection |
CN101797223B (zh) * | 2009-02-06 | 2012-05-23 | 上海交通大学医学院 | 石杉碱甲眼用制剂及其应用 |
JP2012533621A (ja) * | 2009-07-22 | 2012-12-27 | ピュアテック ベンチャーズ | ムスカリン性受容体活性化によって改善される疾患の治療のための方法および組成物 |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
CN112789042A (zh) | 2018-09-28 | 2021-05-11 | 卡鲁娜治疗学有限公司 | 用于治疗由毒蕈碱受体激活所缓解的障碍的组合物和方法 |
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CA2649576A1 (en) | 2006-06-09 | 2007-12-21 | Wyeth | Method for enhancing cognitive function |
TW200808740A (en) * | 2006-06-09 | 2008-02-16 | Wyeth Corp | Succinate salts of 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline and crystalline forms thereof |
TW200808741A (en) | 2006-06-09 | 2008-02-16 | Wyeth Corp | 6-methoxy-8-[4-(1-(5-fluoro)-quinolin-8-yl-piperidin-4-yl)-piperazin-1-yl]-quinoline hydrochloric acid salts |
CL2007003409A1 (es) | 2006-11-28 | 2008-04-11 | Wyeth Corp | Perla de liberacion controlada que comprende una unidad de nucleo central, una primera capa con un agente farmacologico que es un compuesto derivado de piperazina-piperidina, un acidificante, una segunda capa; procedimiento de preparacion; formulacio |
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2006
- 2006-06-08 TW TW095120358A patent/TW200800959A/zh unknown
- 2006-06-09 WO PCT/US2006/022719 patent/WO2006135839A2/en active Application Filing
- 2006-06-09 MX MX2007015678A patent/MX2007015678A/es not_active Application Discontinuation
- 2006-06-09 BR BRPI0613491-2A patent/BRPI0613491A2/pt not_active Application Discontinuation
- 2006-06-09 CA CA002611711A patent/CA2611711A1/en not_active Abandoned
- 2006-06-09 CN CNA2006800292484A patent/CN101243073A/zh active Pending
- 2006-06-09 JP JP2008516005A patent/JP2008543782A/ja active Pending
- 2006-06-09 US US11/450,942 patent/US7671056B2/en not_active Expired - Fee Related
- 2006-06-09 EP EP06772861A patent/EP1888559A2/en not_active Withdrawn
- 2006-06-09 RU RU2007146543/04A patent/RU2007146543A/ru not_active Application Discontinuation
- 2006-06-09 GT GT200600255A patent/GT200600255A/es unknown
- 2006-06-09 PE PE2006000646A patent/PE20070069A1/es not_active Application Discontinuation
- 2006-06-09 AU AU2006257874A patent/AU2006257874A1/en not_active Abandoned
- 2006-06-09 KR KR1020087000800A patent/KR20080021134A/ko not_active Application Discontinuation
- 2006-06-12 AR ARP060102469A patent/AR055059A1/es unknown
-
2007
- 2007-12-05 CR CR9560A patent/CR9560A/es not_active Application Discontinuation
- 2007-12-06 IL IL187972A patent/IL187972A0/en unknown
- 2007-12-07 ZA ZA200710699A patent/ZA200710699B/xx unknown
- 2007-12-11 NO NO20076344A patent/NO20076344L/no not_active Application Discontinuation
-
2008
- 2008-01-10 EC EC2008008094A patent/ECSP088094A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP1888559A2 (en) | 2008-02-20 |
GT200600255A (es) | 2007-07-19 |
IL187972A0 (en) | 2008-03-20 |
US20070027160A1 (en) | 2007-02-01 |
TW200800959A (en) | 2008-01-01 |
CA2611711A1 (en) | 2006-12-21 |
ZA200710699B (en) | 2009-05-27 |
CR9560A (es) | 2008-02-20 |
PE20070069A1 (es) | 2007-03-15 |
AR055059A1 (es) | 2007-08-01 |
RU2007146543A (ru) | 2009-07-20 |
US7671056B2 (en) | 2010-03-02 |
CN101243073A (zh) | 2008-08-13 |
JP2008543782A (ja) | 2008-12-04 |
BRPI0613491A2 (pt) | 2011-01-11 |
MX2007015678A (es) | 2008-02-20 |
WO2006135839A2 (en) | 2006-12-21 |
ECSP088094A (es) | 2008-02-20 |
KR20080021134A (ko) | 2008-03-06 |
AU2006257874A1 (en) | 2006-12-21 |
WO2006135839A3 (en) | 2007-11-22 |
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