NO20075647L - Kjemiske forbindelser - Google Patents
Kjemiske forbindelserInfo
- Publication number
- NO20075647L NO20075647L NO20075647A NO20075647A NO20075647L NO 20075647 L NO20075647 L NO 20075647L NO 20075647 A NO20075647 A NO 20075647A NO 20075647 A NO20075647 A NO 20075647A NO 20075647 L NO20075647 L NO 20075647L
- Authority
- NO
- Norway
- Prior art keywords
- chemical connections
- connections
- chemical
- cancer
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68151505P | 2005-05-16 | 2005-05-16 | |
US72228205P | 2005-09-30 | 2005-09-30 | |
PCT/GB2006/001760 WO2006123113A2 (en) | 2005-05-16 | 2006-05-12 | Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20075647L true NO20075647L (no) | 2007-12-13 |
Family
ID=37087720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20075647A NO20075647L (no) | 2005-05-16 | 2007-11-06 | Kjemiske forbindelser |
Country Status (15)
Country | Link |
---|---|
US (2) | US20080287437A1 (es) |
EP (1) | EP1899323A2 (es) |
JP (1) | JP2008540622A (es) |
KR (1) | KR20080015409A (es) |
AR (1) | AR056354A1 (es) |
AU (1) | AU2006248780B2 (es) |
BR (1) | BRPI0610184A2 (es) |
CA (1) | CA2608009A1 (es) |
IL (1) | IL186845A0 (es) |
MX (1) | MX2007014328A (es) |
NO (1) | NO20075647L (es) |
NZ (1) | NZ564317A (es) |
TW (1) | TW200716606A (es) |
UY (1) | UY29530A1 (es) |
WO (1) | WO2006123113A2 (es) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
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MXPA03005001A (es) * | 2000-12-05 | 2003-09-05 | Vertex Pharma | Inhibidores de n- terminal c-jun cinasas (jnk) y otras proteinas cinasas. |
DK1846394T3 (da) | 2005-02-04 | 2012-01-16 | Astrazeneca Ab | Pyrazolylaminopyridinderivater, der er egnede som kinaseinhibitorer |
DK1853588T3 (da) | 2005-02-16 | 2008-09-15 | Astrazeneca Ab | Kemiske forbindelser |
US20080287437A1 (en) * | 2005-05-16 | 2008-11-20 | Astrazeneca Ab | Pyrazolylaminopyrimidine Derivatives Useful as Tyrosine Kinase Inhibitors |
RU2463302C2 (ru) * | 2005-10-28 | 2012-10-10 | Астразенека Аб | Производные 4-(3-аминопиразол)пиримидина для применения в качестве ингибиторов тирозинкиназы для лечения злокачественного новообразования |
TW200823196A (en) * | 2006-11-01 | 2008-06-01 | Astrazeneca Ab | New use |
WO2008117050A1 (en) * | 2007-03-27 | 2008-10-02 | Astrazeneca Ab | Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer |
JP2010524911A (ja) * | 2007-04-18 | 2010-07-22 | アストラゼネカ アクチボラグ | 5−アミノピラゾール−3−イル−3H−イミダゾ[4,5−b]ピリジン誘導体と癌の治療のためのその使用 |
UY31048A1 (es) * | 2007-04-25 | 2008-11-28 | Astrazeneca Ab | Nuevos compuestos de pirimidina y usos de los mismos |
JP2010526048A (ja) * | 2007-05-04 | 2010-07-29 | アストラゼネカ アクチボラグ | アミノ−チアゾリル−ピリミジン誘導体、および癌の治療のための該誘導体の使用 |
UA99459C2 (en) * | 2007-05-04 | 2012-08-27 | Астразенека Аб | 9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer |
WO2009007753A2 (en) * | 2007-07-11 | 2009-01-15 | Astrazeneca Ab | 4- (3-aminopyrazole) -pyrimidine derivativee and their use as tyrosine kinase inhibitors for the treatment of cancer |
WO2009013545A2 (en) * | 2007-07-26 | 2009-01-29 | Astrazeneca Ab | Chemical compounds |
TW200906818A (en) * | 2007-07-31 | 2009-02-16 | Astrazeneca Ab | Chemical compounds |
WO2009027736A2 (en) * | 2007-08-27 | 2009-03-05 | Astrazeneca Ab | 2,4 diaminopyrimid'lnes for the treatment of myeloproliferative disorders and cancer |
WO2009056886A1 (en) * | 2007-11-01 | 2009-05-07 | Astrazeneca Ab | Pyrimidine derivatives and their use as modulators of fgfr activity |
WO2009095712A2 (en) * | 2008-01-29 | 2009-08-06 | Astrazeneca Ab | Chemical compounds |
RU2010154502A (ru) * | 2008-06-11 | 2012-07-20 | Астразенека Аб (Se) | Трициклические 2,4-диамино-l,3,5-триазиновые производные, пригодные для лечения злокачественного новообразования и миелопролиферативных нарушений |
ES2464461T3 (es) | 2008-09-22 | 2014-06-02 | Array Biopharma, Inc. | Compuestos de imidazo[1,2B]piridazina sustituidos como inhibidores de la TRK cinasa |
KR20110071098A (ko) * | 2008-09-30 | 2011-06-28 | 아스트라제네카 아베 | 복소환 jak 키나제 억제제 |
PL3372605T3 (pl) | 2008-10-22 | 2022-03-07 | Array Biopharma Inc. | Podstawione związki pirazolo[1,5-a]pirymidynowe jako inhibitory kinaz trk |
EP2181980A1 (en) * | 2008-10-28 | 2010-05-05 | Chemo Ibérica, S.A. | A process for the preparation of (R)-1-aminoindanes |
AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
SG10201506591TA (en) | 2010-05-20 | 2015-09-29 | Array Biopharma Inc | Macrocyclic compounds as trk kinase inhibitors |
WO2012050141A1 (ja) * | 2010-10-14 | 2012-04-19 | 住友化学株式会社 | ヘテロ芳香環化合物およびその有害生物防除用途 |
US9102673B2 (en) | 2011-07-12 | 2015-08-11 | Merck Sharp & Dohme Corp. | Substituted pyrrolo[3,2-c]pyridines as TrkA kinase inhibitors |
EP2554544A1 (en) | 2011-08-01 | 2013-02-06 | Almirall, S.A. | Pyridin-2(1h)-one derivatives as jak inhibitors |
EP2748159A1 (en) * | 2011-08-25 | 2014-07-02 | F.Hoffmann-La Roche Ag | Serine/threonine pak1 inhibitors |
RU2014129740A (ru) * | 2011-12-22 | 2016-02-10 | Ф.Хоффманн-Ля Рош Аг | Производные 2,4-диаминопиримидина в качестве ингибиторов серин/треонин киназы |
WO2013176970A1 (en) | 2012-05-22 | 2013-11-28 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
EP3628749A1 (en) | 2013-07-30 | 2020-04-01 | Blueprint Medicines Corporation | Ntrk2 fusions |
WO2015039333A1 (en) | 2013-09-22 | 2015-03-26 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
WO2015039334A1 (en) | 2013-09-22 | 2015-03-26 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
US10231965B2 (en) | 2014-02-20 | 2019-03-19 | Ignyta, Inc. | Molecules for administration to ROS1 mutant cancer cells |
WO2015143654A1 (en) | 2014-03-26 | 2015-10-01 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF |
WO2015143653A1 (en) | 2014-03-26 | 2015-10-01 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF |
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WO2016067803A1 (ja) * | 2014-10-30 | 2016-05-06 | 富士フイルム株式会社 | 有機アミン塩及びその製造方法、並びに、アゾ色素の製造方法 |
FI3699181T3 (fi) | 2014-11-16 | 2023-03-28 | Array Biopharma Inc | Kiteinen muoto (s)-n-(5-((r)-2-(2,5-diluorifenyyli)-pyrrolidin-1-yyli)-pyratsolo[1,5-a]pyrimidin-3-yyli)-3-hydroksipyrrolidiini-1-karboksamidivetyysulfaatista |
KR102595599B1 (ko) | 2014-12-02 | 2023-11-02 | 이그니타, 인코포레이티드 | 신경모세포종의 치료를 위한 병용 |
WO2016161572A1 (en) | 2015-04-08 | 2016-10-13 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
MA41667A1 (fr) | 2015-06-01 | 2018-08-31 | Loxo Oncology Inc | Procede de diagnostic et de traitement du cancer |
EA035049B1 (ru) | 2015-07-16 | 2020-04-22 | Аррэй Байофарма Инк. | СОЕДИНЕНИЯ ЗАМЕЩЕННОГО ПИРАЗОЛО[1,5-a]ПИРИДИНА В КАЧЕСТВЕ ИНГИБИТОРОВ RET КИНАЗЫ |
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KR20180096621A (ko) | 2015-12-18 | 2018-08-29 | 이그니타, 인코포레이티드 | 암의 치료용 조합물 |
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TWI704148B (zh) | 2016-10-10 | 2020-09-11 | 美商亞雷生物製藥股份有限公司 | 作為ret激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物 |
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EP3740491A1 (en) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors |
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2006
- 2006-05-12 US US11/914,492 patent/US20080287437A1/en not_active Abandoned
- 2006-05-12 BR BRPI0610184-4A patent/BRPI0610184A2/pt not_active IP Right Cessation
- 2006-05-12 MX MX2007014328A patent/MX2007014328A/es unknown
- 2006-05-12 KR KR1020077026987A patent/KR20080015409A/ko not_active Application Discontinuation
- 2006-05-12 CA CA002608009A patent/CA2608009A1/en not_active Abandoned
- 2006-05-12 JP JP2008511776A patent/JP2008540622A/ja active Pending
- 2006-05-12 EP EP06727105A patent/EP1899323A2/en not_active Withdrawn
- 2006-05-12 NZ NZ564317A patent/NZ564317A/en not_active IP Right Cessation
- 2006-05-12 WO PCT/GB2006/001760 patent/WO2006123113A2/en active Application Filing
- 2006-05-12 AU AU2006248780A patent/AU2006248780B2/en not_active Ceased
- 2006-05-15 UY UY29530A patent/UY29530A1/es unknown
- 2006-05-16 TW TW095117309A patent/TW200716606A/zh unknown
- 2006-05-16 AR ARP060101974A patent/AR056354A1/es not_active Application Discontinuation
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2007
- 2007-10-22 IL IL186845A patent/IL186845A0/en unknown
- 2007-11-06 NO NO20075647A patent/NO20075647L/no not_active Application Discontinuation
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- 2010-02-26 US US12/713,777 patent/US8114989B2/en not_active Expired - Fee Related
Also Published As
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NZ564317A (en) | 2011-01-28 |
MX2007014328A (es) | 2008-02-12 |
CA2608009A1 (en) | 2006-11-23 |
US8114989B2 (en) | 2012-02-14 |
BRPI0610184A2 (pt) | 2012-09-25 |
EP1899323A2 (en) | 2008-03-19 |
AU2006248780A1 (en) | 2006-11-23 |
TW200716606A (en) | 2007-05-01 |
JP2008540622A (ja) | 2008-11-20 |
US20080287437A1 (en) | 2008-11-20 |
IL186845A0 (en) | 2008-02-09 |
US20100210648A1 (en) | 2010-08-19 |
AU2006248780B2 (en) | 2010-06-03 |
UY29530A1 (es) | 2006-12-29 |
WO2006123113A3 (en) | 2007-01-04 |
WO2006123113A2 (en) | 2006-11-23 |
AR056354A1 (es) | 2007-10-03 |
KR20080015409A (ko) | 2008-02-19 |
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