NO20075227L - Treatment of eczemas - Google Patents

Treatment of eczemas

Info

Publication number
NO20075227L
NO20075227L NO20075227A NO20075227A NO20075227L NO 20075227 L NO20075227 L NO 20075227L NO 20075227 A NO20075227 A NO 20075227A NO 20075227 A NO20075227 A NO 20075227A NO 20075227 L NO20075227 L NO 20075227L
Authority
NO
Norway
Prior art keywords
treatment
inhibition
tyrosine kinase
protein tyrosine
eczema
Prior art date
Application number
NO20075227A
Other languages
English (en)
Inventor
Morten Sloth Weidner
Original Assignee
Astion Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astion Pharma As filed Critical Astion Pharma As
Publication of NO20075227L publication Critical patent/NO20075227L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Den gjeldende oppfinnelsen er relatert til ett nyoppdaget prinsipp for behandling av dermatologiske sykdommer som omfatter inhibering av flere avgjørende trinn i den inflammatoriske kaskaden, inkludert minst inhiberingen av ett eller flere av enzymene protein tyrosin kinase Syk, protein tyrosin kinase ZAP-70 og fosfodiesterase IV (PDE-IV). Oppfinnelsen tilveiebringer medikamenter og fremgangsmåter for behandlingen av inflammatoriske dermatologiske sykdommer, særlig eksemer, som omfatter Oxaprozin eller en nært beslektet forbindelse eller et salt derav.
NO20075227A 2005-03-30 2007-10-12 Treatment of eczemas NO20075227L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DKPA200500437 2005-03-30
DKPA200500438 2005-03-30
US69477405P 2005-06-27 2005-06-27
DKPA200500949 2005-06-27
DKPA200500948 2005-06-27
US69504005P 2005-06-28 2005-06-28
PCT/DK2006/000178 WO2006102898A2 (en) 2005-03-30 2006-03-30 Oxaprozin or a closely related compound for the treatment of eczema

Publications (1)

Publication Number Publication Date
NO20075227L true NO20075227L (no) 2007-12-09

Family

ID=36215671

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20075199A NO20075199L (no) 2005-03-30 2007-10-11 Treatment or prevention of pruritus
NO20075218A NO20075218L (no) 2005-03-30 2007-10-12 Dermatological compositions and salts for the treatment of dermatological diseases
NO20075227A NO20075227L (no) 2005-03-30 2007-10-12 Treatment of eczemas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20075199A NO20075199L (no) 2005-03-30 2007-10-11 Treatment or prevention of pruritus
NO20075218A NO20075218L (no) 2005-03-30 2007-10-12 Dermatological compositions and salts for the treatment of dermatological diseases

Country Status (12)

Country Link
EP (3) EP1707199A1 (no)
JP (3) JP2008534526A (no)
KR (3) KR20080005526A (no)
AU (3) AU2006228869A1 (no)
BR (3) BRPI0609535A2 (no)
CA (3) CA2605121A1 (no)
EA (3) EA200702026A1 (no)
EC (3) ECSP077843A (no)
IL (3) IL186022A0 (no)
MX (3) MX2007012050A (no)
NO (3) NO20075199L (no)
WO (3) WO2006102899A2 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0821537D0 (en) * 2008-11-25 2008-12-31 Union Life Sciences Ltd Therapeutic target
CA2997842A1 (en) * 2015-09-18 2017-03-23 Delivra Inc. Transdermal formulations for delivery of propionic and acetic acid nsaids, and their use in the treatment of nsaid-responsive diseases and conditions
WO2018031529A1 (en) * 2016-08-08 2018-02-15 Avedro, Inc. Systems and methods for cross-linking treatments of an eye
CN115998871A (zh) 2016-10-25 2023-04-25 蒂库尔有限公司 Fabp4作为皮肤病中的治疗靶
CN111683641A (zh) * 2017-12-07 2020-09-18 德玛万科学有限公司 Pde-4抑制剂的局部用软膏剂制剂及其在治疗皮肤病况中的应用
RU2685436C1 (ru) * 2018-06-22 2019-04-18 ЗАО "ФармФирма "Сотекс" Трансдермальный препарат для лечения и профилактики болезней суставов и мягких тканей
JP2020100575A (ja) * 2018-12-20 2020-07-02 小林製薬株式会社 皮膚外用組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE32084B1 (en) 1967-06-07 1973-04-04 Wyeth John & Brother Ltd Thiazole derivatives
US3578671A (en) 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles
IE52909B1 (en) * 1981-04-28 1988-04-13 Wyeth John & Brother Ltd Oxazole derivatives
US4659728A (en) * 1985-02-25 1987-04-21 American Home Products Corporation Hydroxy substituted 4,5-diphenyl-2-oxazole propanoic acid
EP0270316A3 (en) * 1986-12-04 1989-12-06 Pfizer Inc. Topical compositions comprising 1-substituted imidazoles and nsaids for treatment of acne
US6090834A (en) 1993-05-21 2000-07-18 G.D. Searle & Co. Substituted oxazoles for the treatment of inflammation
US5380738A (en) 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
AU690155B2 (en) 1993-10-20 1998-04-23 Boots Company Plc, The Ibuprofen and flurbiprofen as anti-pruritic agents
JPH07316075A (ja) 1994-05-26 1995-12-05 Pola Chem Ind Inc 皮膚外用剤
GB9606429D0 (en) 1996-03-27 1996-06-05 Boots Co Plc Pharmaceutical compositions
ES2248850T3 (es) * 1996-05-20 2006-03-16 G.D. Searle Llc. Formulaciones farmaceuticas que contienen sales de potasiom sodio y tris de oxaprozina.
US5976566A (en) * 1997-08-29 1999-11-02 Macrochem Corporation Non-steroidal antiinflammtory drug formulations for topical application to the skin
IL142037A0 (en) * 2001-03-15 2002-03-10 Agis Ind 1983 Ltd Pharmaceutical compositions containing a non-steroidal anti-inflammatory drug
WO2005009342A2 (en) 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050232957A1 (en) 2004-04-14 2005-10-20 Katz Kenneth A Compositions and methods for moisturizing skin

Also Published As

Publication number Publication date
CA2603300A1 (en) 2006-10-05
ECSP077845A (es) 2008-02-20
CA2605121A1 (en) 2006-10-05
JP2008534526A (ja) 2008-08-28
ECSP077846A (es) 2008-02-20
EA200702026A1 (ru) 2008-04-28
KR20080005525A (ko) 2008-01-14
WO2006102898A2 (en) 2006-10-05
ECSP077843A (es) 2008-02-20
IL186022A0 (en) 2008-02-09
EP1707200A1 (en) 2006-10-04
EP1707199A1 (en) 2006-10-04
WO2006102899A2 (en) 2006-10-05
MX2007012051A (es) 2008-02-22
WO2006102898A3 (en) 2006-12-28
JP2008534528A (ja) 2008-08-28
MX2007012052A (es) 2008-02-22
BRPI0607648A2 (pt) 2009-09-22
EA200702023A1 (ru) 2008-04-28
KR20080011280A (ko) 2008-02-01
AU2006228869A1 (en) 2006-10-05
KR20080005526A (ko) 2008-01-14
BRPI0609535A2 (pt) 2010-04-13
AU2006228870A1 (en) 2006-10-05
MX2007012050A (es) 2008-03-11
BRPI0609653A2 (pt) 2010-04-20
WO2006102900A1 (en) 2006-10-05
IL186020A0 (en) 2008-01-20
AU2006228871A1 (en) 2006-10-05
EP1707201A1 (en) 2006-10-04
WO2006102899A3 (en) 2006-12-28
CA2603297A1 (en) 2006-10-05
NO20075199L (no) 2008-01-02
EA200702027A1 (ru) 2008-02-28
JP2008534527A (ja) 2008-08-28
IL186021A0 (en) 2008-02-09
NO20075218L (no) 2007-12-27

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