NO20073083L - Nye porfyrinderivater, fortrinnsvis kloriner og/eller bakteriokloriner, og anvendelse derav i fotodynamisk terapi - Google Patents
Nye porfyrinderivater, fortrinnsvis kloriner og/eller bakteriokloriner, og anvendelse derav i fotodynamisk terapiInfo
- Publication number
- NO20073083L NO20073083L NO20073083A NO20073083A NO20073083L NO 20073083 L NO20073083 L NO 20073083L NO 20073083 A NO20073083 A NO 20073083A NO 20073083 A NO20073083 A NO 20073083A NO 20073083 L NO20073083 L NO 20073083L
- Authority
- NO
- Norway
- Prior art keywords
- photodynamic therapy
- bacteriochlorines
- chlorines
- porphyrin derivatives
- different
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
Foreliggende oppfinnelse gjelder derivater av porfyrin, fortrinnsvis klorider og/eller bakterioklorider, med formelen (I) og (II) som kan anvendes i fotodynamisk terapi. Ifølge oppfinnelsen står X1-X8, som kan være like eller forskjellige, alle for halogenatomer eller hydrogenatomer, og R1-R4 som kan være like eller forskjellige, alle er utvalgt fra følgende grupper: -OH, aminosyrer, -OR, -NHR og et kloratom, hvori R er en C1-12-alkylgruppe. Oppfinnelsen gjelder også et antikreftmedikament, et antiviralt medikament og/eller et antimikrobielt medikament for anvendelse i mennesker eller dyr, som inneholder én eller flere forbindelser med formel I eller II som den viktigste aktive bestanddel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0412149A FR2877943B1 (fr) | 2004-11-16 | 2004-11-16 | Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique |
PCT/EP2005/012212 WO2006053707A1 (fr) | 2004-11-16 | 2005-11-10 | Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorines et leurs applications en therapie photodynamique |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20073083L true NO20073083L (no) | 2007-06-15 |
NO338966B1 NO338966B1 (no) | 2016-11-07 |
Family
ID=34954077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073083A NO338966B1 (no) | 2004-11-16 | 2007-06-15 | Nye porfyrinderivater, fortrinnsvis kloriner og/eller bakteriokloriner, fremgangsmåte for fremstilling derav, og anvendelse derav som antikreft, og/eller antiviralt og/eller antimikrobielt medikament i fotodynamisk terapi |
Country Status (18)
Country | Link |
---|---|
US (1) | US8592404B2 (no) |
EP (1) | EP1811994B1 (no) |
JP (1) | JP5226317B2 (no) |
CN (1) | CN101102766B (no) |
AT (1) | ATE399009T1 (no) |
AU (1) | AU2005306055B2 (no) |
BR (1) | BRPI0517664B8 (no) |
CA (1) | CA2587328C (no) |
DE (1) | DE602005007769D1 (no) |
DK (1) | DK1811994T3 (no) |
ES (1) | ES2309815T3 (no) |
FR (1) | FR2877943B1 (no) |
NO (1) | NO338966B1 (no) |
PL (1) | PL1811994T3 (no) |
PT (1) | PT1811994E (no) |
RU (1) | RU2399622C2 (no) |
WO (1) | WO2006053707A1 (no) |
ZA (1) | ZA200703516B (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5955559B2 (ja) * | 2008-09-18 | 2016-07-20 | バイオリテック ファーマ マーケティング リミテッド | 非対称メソ置換ポルフィリンおよびクロリンのpdtへの適用と新規方法 |
GB0819594D0 (en) * | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
WO2011090333A2 (ko) * | 2010-01-20 | 2011-07-28 | 주식회사 진코스 | 클로린 유도체와 불포화 지방산의 접합체, 이를 함유하는 광감작제, 및 이를 포함하는 광역학 치료에 사용하기 위한 암 치료용 조성물 |
WO2011089509A1 (en) * | 2010-01-22 | 2011-07-28 | Council Of Scientific & Industrial Research | A process for the preparation of novel porphyrin derivatives and their use as pdt agents and fluorescence probes |
PL2870159T3 (pl) * | 2010-07-22 | 2018-01-31 | Biolitec Unternehmensbeteiligungs Ii Ag | Zastosowanie β-funkcjonalizowanych dihydroksychloryn do PDT |
WO2013015774A1 (en) * | 2011-07-22 | 2013-01-31 | Biolitec Pharma Marketing Ltd | Glyco-substituted dihydroxy-chlorins and b-functionalized chlorins for anti-microbial photodynamic therapy |
RU2476218C1 (ru) * | 2012-02-17 | 2013-02-27 | Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") | Фотосенсибилизаторы для фотодинамической терапии |
RU2521327C1 (ru) * | 2012-12-12 | 2014-06-27 | Федеральное государственное бюджетное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения Российской Федерации" (ФГБУ "МНИОИ им. П.А. Герцена" Минздрава России) | Препарат для фотодинамической терапии и способ фотодинамической терапии рака с его использованием |
AU2016238484B2 (en) | 2015-03-20 | 2020-03-19 | Luzitin, S.A. | Atropisomers of halogenated tetraphenylbacteriochlorins and chlorins and their use in photodynamic therapy |
CA2985187C (en) * | 2015-05-07 | 2024-01-02 | Luzitin, S.A. | Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof |
RU2692999C2 (ru) * | 2017-10-13 | 2019-06-28 | Общество с ограниченной ответственностью "Клиника профессора Пасман" (ООО "Клиника профессора Пасман") | Способ лечения хронического эндометрита |
CN109481696B (zh) * | 2018-12-22 | 2020-10-02 | 吉林大学 | 用于癌症光动力治疗和化学治疗的药物及其制备方法 |
EP3983486A1 (en) * | 2019-06-14 | 2022-04-20 | Universidade de Coimbra | Small cationic ortho-5,15-di-heteroaryl-porphyrins derivatives and their applications in photoinactivation of microorganisms |
US11850233B2 (en) | 2019-10-28 | 2023-12-26 | Matibur Rahaman Zamadar | Reduced adaptive microbial resistance treatment for flesh eating disease (necrotizing fasciitis) |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3809671A1 (de) * | 1988-03-18 | 1989-09-28 | Schering Ag | Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
NO180167C (no) * | 1994-09-08 | 1997-02-26 | Photocure As | Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol |
PT983272E (pt) * | 1997-05-07 | 2004-03-31 | Univ British Columbia | Nova classe de compostos fotoactivos derivados de benzoporfirina |
DE19831217A1 (de) * | 1998-07-03 | 2000-01-05 | Schering Ag | Neue Porphyrinderivate, diese enthaltende pharmazeutische Mittel und ihre Verwendung in der photodynamischen Therapie und MRI-Diagnostik |
EP1279676A1 (en) * | 2001-07-19 | 2003-01-29 | Institut Curie | Porphyrin derivatives for photodynamic therapy |
GB0121023D0 (en) * | 2001-08-30 | 2001-10-24 | Norwegian Radium Hospital Res | Compound |
PT102721B (pt) * | 2002-02-01 | 2011-01-24 | Cipan Companhia Industr Prod De Antibioticos S A | Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação |
-
2004
- 2004-11-16 FR FR0412149A patent/FR2877943B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-10 JP JP2007540608A patent/JP5226317B2/ja active Active
- 2005-11-10 DE DE602005007769T patent/DE602005007769D1/de active Active
- 2005-11-10 PT PT05810755T patent/PT1811994E/pt unknown
- 2005-11-10 RU RU2007122529/04A patent/RU2399622C2/ru active
- 2005-11-10 WO PCT/EP2005/012212 patent/WO2006053707A1/fr active IP Right Grant
- 2005-11-10 AT AT05810755T patent/ATE399009T1/de active
- 2005-11-10 BR BRPI0517664A patent/BRPI0517664B8/pt active IP Right Grant
- 2005-11-10 PL PL05810755T patent/PL1811994T3/pl unknown
- 2005-11-10 DK DK05810755T patent/DK1811994T3/da active
- 2005-11-10 US US11/719,295 patent/US8592404B2/en active Active
- 2005-11-10 CA CA2587328A patent/CA2587328C/fr active Active
- 2005-11-10 CN CN2005800466547A patent/CN101102766B/zh active Active
- 2005-11-10 ES ES05810755T patent/ES2309815T3/es active Active
- 2005-11-10 AU AU2005306055A patent/AU2005306055B2/en active Active
- 2005-11-10 ZA ZA200703516A patent/ZA200703516B/xx unknown
- 2005-11-10 EP EP05810755A patent/EP1811994B1/fr active Active
-
2007
- 2007-06-15 NO NO20073083A patent/NO338966B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
RU2007122529A (ru) | 2008-12-27 |
BRPI0517664B8 (pt) | 2021-05-25 |
DE602005007769D1 (de) | 2008-08-07 |
EP1811994B1 (fr) | 2008-06-25 |
ZA200703516B (en) | 2008-09-25 |
EP1811994A1 (fr) | 2007-08-01 |
AU2005306055A1 (en) | 2006-05-26 |
JP5226317B2 (ja) | 2013-07-03 |
ATE399009T1 (de) | 2008-07-15 |
CN101102766A (zh) | 2008-01-09 |
CA2587328C (fr) | 2011-10-11 |
PT1811994E (pt) | 2008-12-05 |
ES2309815T3 (es) | 2008-12-16 |
BRPI0517664A2 (pt) | 2010-10-05 |
NO338966B1 (no) | 2016-11-07 |
CN101102766B (zh) | 2010-12-15 |
BRPI0517664B1 (pt) | 2019-01-22 |
US20090149525A1 (en) | 2009-06-11 |
US8592404B2 (en) | 2013-11-26 |
FR2877943B1 (fr) | 2008-09-05 |
WO2006053707A1 (fr) | 2006-05-26 |
FR2877943A1 (fr) | 2006-05-19 |
RU2399622C2 (ru) | 2010-09-20 |
DK1811994T3 (da) | 2008-10-20 |
CA2587328A1 (fr) | 2006-05-26 |
AU2005306055B2 (en) | 2011-09-01 |
PL1811994T3 (pl) | 2009-01-30 |
JP2008520558A (ja) | 2008-06-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20073083L (no) | Nye porfyrinderivater, fortrinnsvis kloriner og/eller bakteriokloriner, og anvendelse derav i fotodynamisk terapi | |
DE60140814D1 (de) | N-phenyl-2-pyrimidine-amine derivatives | |
UY28510A1 (es) | Compuestos quimicos | |
MY139303A (en) | Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof | |
MY139302A (en) | Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof | |
HRP20040317A2 (en) | 1,8-naphthyridine derivatives as antidiabetics | |
DE602004024375D1 (de) | Carboxamidderivate | |
BR0210507A (pt) | Azaindóis | |
HUP0401192A2 (hu) | Fényérzékenyítő szer alkalmazása sebek kezelésére adható gyógyászati készítmény előállítására | |
UY30316A1 (es) | Derivados sustituidos de benzamidas, nicotinamidas, propanamidas, acetamidas y carboxamidas n-(2-(piperidin-1-ilmetil)ciclohexil)sustituidas, procesos de preparacion, composiciones conteniéndolos y aplicaciones | |
SE0201544D0 (sv) | Novel compounds and thier use | |
UY28536A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. | |
ATE499372T1 (de) | Azabenzimidalzolderivate, ihre herstellung und ihre verwendung als antikrebsmittel | |
UY31334A1 (es) | 3a,4,5,6,7,7a-hexahidro-3h-benzoimidazol y derivaods de 3a, 4,5,6,,7,7a-hexahidro-3-indol, enantiómeros, diastereoisómeros, sales farmacéuticamente aceptadas, mezclas, composiciones, preparaciones y aplicaciones de las mismas | |
UY30397A1 (es) | Derivados sustituidos de la (3as, 7as)-1,3a,4,5,6,7-hexahidro-3h-benzoimidazol-2-ona, proceso de preparacion, composiciones conteniéndolos yaplicaciones | |
UY28356A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos | |
SE0300908D0 (sv) | Azaindole derivatives, preparations thereof, uses thereof and compositions containing them | |
UY28357A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparación de los mismos y sus usos | |
SE0302570D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
UY28535A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. | |
UY28537A1 (es) | Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos. | |
ATE325809T1 (de) | Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure | |
SE0403117D0 (sv) | New compounds 1 | |
MXPA05011671A (es) | Nuevos derivados de anilina, su manufactura y su uso como agentes farmaceuticos. | |
UY29043A1 (es) | Derivados de diarilmetil piperazina, preparaciones de los mismos y usos de los mismos |