NO20065101L - Forbindelse WS727713 - Google Patents

Forbindelse WS727713

Info

Publication number
NO20065101L
NO20065101L NO20065101A NO20065101A NO20065101L NO 20065101 L NO20065101 L NO 20065101L NO 20065101 A NO20065101 A NO 20065101A NO 20065101 A NO20065101 A NO 20065101A NO 20065101 L NO20065101 L NO 20065101L
Authority
NO
Norway
Prior art keywords
compound
relates
present
pseudonocardia
culturing
Prior art date
Application number
NO20065101A
Other languages
English (en)
Inventor
Takanao Otsuka
Hirotsugu Ueda
Keiko Fujie
Hideyuki Muramatsu
Michizane Hashimoto
Shigehiro Takase
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004901919A external-priority patent/AU2004901919A0/en
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of NO20065101L publication Critical patent/NO20065101L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D259/00Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00Subject matter not provided for in other groups of this subclass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/06Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A61Q5/065Preparations for temporary colouring the hair, e.g. direct dyes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Abstract

Den foreliggende oppfinnelsen angår en ny forbindelse som er nyttig som modulator av melanokortinreseptorer. Den foreliggende oppfinnelsen angår især en forbindelse WS727713, en fremgangsmåte for fremstilling av forbindelsen ved dyrking, i et dyrkingsmedium, en WS727713-produserende stamme tilhørende Pseudonocardia- slekten og utvinne forbindelsen fra en dyrkingsvæske,. et farmasøytisk preparat som inneholder forbindelsen, bruk av forbindelsen for fremstilling av et legemiddel eller kosmetikk for melanokortinreseptormodulering, bruk av forbindelsen for fremstilling av et medikament eller kosmetikk for behandling eller forebyggelse av iskemi-/reperfusjonsskade, inflammatoriske hjerne- og nyresykdommer, hepatitt, sepsis/septisk sjokk, hypoksisk sjokk, akutt respiratorisk stressyndrom (ARDS), revmatisk artritt (RA), giktartritt, aortaregurgitasjon (AR), juvenil kronisk artritt, osteoartritt, nefritt, induksjon av toleranse, kontakthypersensitivitet, inflammatorisk tarmsykdom (IBD), seksuell dysfunksjon, transplantasjon, smerte, sykdomsprogresjon av HIV, postinflammatorisk hypopigmentasjon, tinea versicolor, idiopatisk guttat hypomelanose, feber, funksjonell tarmsykdom, overvekt, metthetseffekt, diabetes mellitus, modulering av dermal eksokrin funksjon, kanitis (canities circumscripta), grått hår, pankreatitt, fibrotiske lidelser (hypertropiske arr, keloider, lokalisert skierodermi, systematisk sklerose, sklerodermisk transplantat-mot-vert hudsykdom, levercirrhose, idiopatisk og bleomysinindusert lungefibrose, sykolsporinindusert nevropati), uveitt (spesielt ved Behcets syndrom og sarkoidose), vaskulitt, mikrobielle infeksjoner, cøliaki, vulvar vestibulittsyndrom, melanom invasjon, anoreksi eller noe lignende.
NO20065101A 2004-04-08 2006-11-06 Forbindelse WS727713 NO20065101L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2004901919A AU2004901919A0 (en) 2004-04-08 New Compound
PCT/JP2005/005653 WO2005097973A1 (en) 2004-04-08 2005-03-22 Compound ws 727713

Publications (1)

Publication Number Publication Date
NO20065101L true NO20065101L (no) 2006-11-06

Family

ID=34961861

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065101A NO20065101L (no) 2004-04-08 2006-11-06 Forbindelse WS727713

Country Status (21)

Country Link
US (3) US7741085B2 (no)
EP (1) EP1751273B1 (no)
JP (3) JP4793265B2 (no)
KR (4) KR20100118615A (no)
CN (1) CN1977040B (no)
AT (1) ATE498678T1 (no)
BR (1) BRPI0508787A (no)
CA (1) CA2563498C (no)
DE (1) DE602005026380D1 (no)
DK (1) DK1751273T3 (no)
ES (1) ES2358352T3 (no)
HK (1) HK1103420A1 (no)
IL (1) IL178476A0 (no)
MX (1) MXPA06011521A (no)
NO (1) NO20065101L (no)
PL (1) PL1751273T3 (no)
PT (1) PT1751273E (no)
RU (1) RU2407785C2 (no)
TW (1) TWI352736B (no)
WO (1) WO2005097973A1 (no)
ZA (1) ZA200609241B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030006199A (ko) * 2001-07-12 2003-01-23 남기철 고순도 칼슘 수용액의 제조방법 및 그로부터 생성된고순도 칼슘 수용액
KR20020057845A (ko) * 2002-04-09 2002-07-12 (주)마이크로쉘 탄산칼슘류의 제조에 있어서 브로어를 이용한 이송방법 및마이크로파를 이용한 입도제어기술
DE602005026380D1 (de) * 2004-04-08 2011-03-31 Astellas Pharma Inc Verbindung ws727713
RU2500410C2 (ru) * 2011-08-05 2013-12-10 Виктор Владимирович Редькин Применение лизата актиномицетов для приготовления наружных средств ухода за ногтями
CN102296039B (zh) * 2011-08-12 2013-04-24 中国科学院南海海洋研究所 一种假诺卡氏菌及利用其制备Deoxynyboquinone的方法
JP2013180961A (ja) * 2012-02-29 2013-09-12 Astellas Pharma Inc Ws727713含有固形製剤
US10232018B2 (en) 2013-03-14 2019-03-19 Mallinckrodt Ard Ip Limited ACTH for treatment of acute respiratory distress syndrome

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795788A (nl) 1972-02-22 1973-08-22 Akzo Nv Werkwijze ter bereiding van peptiden en peptide-derivaten en de toepassing hiervan
JPS58138380A (ja) 1982-02-12 1983-08-17 Dainippon Ink & Chem Inc 微生物
JPS58179498A (ja) 1982-04-13 1983-10-20 Dainippon Ink & Chem Inc 微生物による11α−ヒドロキシル化アンドロスタン系化合物の製造方法
DE19532317A1 (de) * 1995-09-01 1997-03-06 Haarmann & Reimer Gmbh Verfahren zur Herstellung von Vanillin und dafür geeignete Mikroorganismen
US6074872A (en) * 1996-05-15 2000-06-13 The Scripps Research Institute Cortistatin: nucleic acids that encode these neuropeptides
EP1040351B1 (en) * 1997-12-16 2007-07-18 Merck & Co., Inc. C-terminal region of agouti-related transcript (art) protein
EP1076649A4 (en) * 1998-04-28 2010-06-02 Trega Biosciences Inc ISOQUINOLINE-BASED COMPOUNDS IN PLACE OF MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USE
WO2000033658A1 (en) * 1998-12-09 2000-06-15 Eleanor Roosevelt Institute Composition and method for regulation of body weight and associated conditions
MXPA02007289A (es) * 2000-01-28 2003-09-22 Melacure Therapeutics Ab Agonistas y antagonistas novedosos de receptores de melanocortina.
EA200201119A1 (ru) * 2000-06-28 2003-06-26 Пфайзер Продактс Инк. Лиганды меланокортиновых рецепторов
BR0113637A (pt) * 2000-08-30 2004-02-25 Hoffmann La Roche Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4
KR100681670B1 (ko) * 2001-02-14 2007-02-09 주식회사 엘지생활건강 [감마 히드록시 엔- 메틸-엘-루신9]사이클로스포린 에이를유효성분으로 하는 모발 성장 촉진제
DE602005026380D1 (de) * 2004-04-08 2011-03-31 Astellas Pharma Inc Verbindung ws727713

Also Published As

Publication number Publication date
TWI352736B (en) 2011-11-21
RU2006139138A (ru) 2008-05-20
KR20100051751A (ko) 2010-05-17
TW200602066A (en) 2006-01-16
US20100297735A1 (en) 2010-11-25
KR20100118615A (ko) 2010-11-05
JP5721516B2 (ja) 2015-05-20
EP1751273A1 (en) 2007-02-14
JP2011201884A (ja) 2011-10-13
KR20110086647A (ko) 2011-07-28
CA2563498A1 (en) 2005-10-20
US20070254829A1 (en) 2007-11-01
HK1103420A1 (en) 2007-12-21
IL178476A0 (en) 2007-02-11
KR101176758B1 (ko) 2012-08-23
CN1977040A (zh) 2007-06-06
US8133713B2 (en) 2012-03-13
PT1751273E (pt) 2011-03-07
JP2007532476A (ja) 2007-11-15
MXPA06011521A (es) 2007-03-21
JP4793265B2 (ja) 2011-10-12
JP2014040456A (ja) 2014-03-06
CA2563498C (en) 2013-05-21
KR101092716B1 (ko) 2011-12-09
DK1751273T3 (da) 2011-05-02
EP1751273B1 (en) 2011-02-16
US20120214731A1 (en) 2012-08-23
BRPI0508787A (pt) 2007-09-04
US7741085B2 (en) 2010-06-22
RU2407785C2 (ru) 2010-12-27
PL1751273T3 (pl) 2011-07-29
WO2005097973A1 (en) 2005-10-20
US8592378B2 (en) 2013-11-26
KR20070008682A (ko) 2007-01-17
CN1977040B (zh) 2011-01-12
ZA200609241B (en) 2008-06-25
ATE498678T1 (de) 2011-03-15
ES2358352T3 (es) 2011-05-09
DE602005026380D1 (de) 2011-03-31

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