NO20063784L - Fremgangsmate for a tilveiebringe et virusfritt antistoffpreparat - Google Patents

Fremgangsmate for a tilveiebringe et virusfritt antistoffpreparat

Info

Publication number
NO20063784L
NO20063784L NO20063784A NO20063784A NO20063784L NO 20063784 L NO20063784 L NO 20063784L NO 20063784 A NO20063784 A NO 20063784A NO 20063784 A NO20063784 A NO 20063784A NO 20063784 L NO20063784 L NO 20063784L
Authority
NO
Norway
Prior art keywords
approx
solution
virus
antibody preparation
antibodies
Prior art date
Application number
NO20063784A
Other languages
English (en)
Inventor
Andrea Buchacher
Juergen Romisch
Guenther Iberer
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34910983&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20063784(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of NO20063784L publication Critical patent/NO20063784L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Sammendrag En fremgangsmåte for fremstilling av et renset, virus inaktivert og virusfritt antistoffpreparat fra en startløsning omfattende antistoffer og forurensinger, fremgangsmåten omfatter trinnene av: 5 (a) justering av pH til startløsningen til ca. 4,6 til ca. 4,95 spesielt til ca. 4,8 til ca. 4,95 for å produsere en intermediat-løsning; (b) tilsette kaprylat- og/eller heptanoat-ioner til intermediat-løsningen og vedlikeholding av pH på ca. 4,6 til ca. 4,95 spesielt pH på ca. 4,8 til ca. 4,95, hvor et bunnfall dannes og antistoffene vesentlig blir 10 presentert i supernatanten; (c) inkubering av supernatant-løsningen under betingelser av kaprylatog/eller heptanoat-ionekonsentrasjon, tid, pH og temperatur valgfritt konsentrering og diafiltrating av filtrat-løsningen før pH-justering; (d) påføre den filtrerte løsningen på minst en anionbytter-resin og 15 valgfritt med to forskjellige anionbytter-resiner under betingelser som tillater binding av forurensninger til resinet mens ikke tillater signifikant binding av antistoffene til resinet, hvori et renset, virus inaktivert og virusfritt antistoffpreparat blir produsert.
NO20063784A 2004-02-27 2006-08-24 Fremgangsmate for a tilveiebringe et virusfritt antistoffpreparat NO20063784L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54810704P 2004-02-27 2004-02-27
PCT/EP2005/050812 WO2005082937A2 (en) 2004-02-27 2005-02-25 A method of providing a purified, virus safe antibody preparation

Publications (1)

Publication Number Publication Date
NO20063784L true NO20063784L (no) 2006-09-25

Family

ID=34910983

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063784A NO20063784L (no) 2004-02-27 2006-08-24 Fremgangsmate for a tilveiebringe et virusfritt antistoffpreparat

Country Status (18)

Country Link
US (1) US7553938B2 (no)
EP (2) EP1718675B2 (no)
JP (1) JP5042817B2 (no)
KR (1) KR101206788B1 (no)
CN (1) CN1922207B (no)
AU (1) AU2005217148B2 (no)
BR (1) BRPI0508096B8 (no)
CA (1) CA2557229C (no)
DK (1) DK1718675T3 (no)
ES (1) ES2407380T5 (no)
IL (1) IL177541A (no)
NO (1) NO20063784L (no)
PL (1) PL1718675T3 (no)
PT (1) PT1718675E (no)
RU (1) RU2337109C2 (no)
UA (1) UA87836C2 (no)
WO (1) WO2005082937A2 (no)
ZA (1) ZA200607119B (no)

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FR2977893B1 (fr) * 2011-07-11 2015-02-20 Lab Francais Du Fractionnement Procede de preparation d'un concentre d'immunoglobulines polyvalentes
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WO2014141150A1 (en) * 2013-03-15 2014-09-18 Glaxosmithkline Intellectual Property (No.2) Limited Methods for purifying antibodies
JP6373376B2 (ja) 2013-11-15 2018-08-15 ノバルティス アーゲー 残留細胞培養不純物の除去
RU2561596C2 (ru) * 2013-12-18 2015-08-27 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации Способ приготовления вирусинактивированных растворов иммуноглобулинов с низким остаточным содержанием каприловой кислоты
TWI671312B (zh) 2014-01-17 2019-09-11 美商健臻公司 無菌層析法及製法
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
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US10550148B2 (en) 2014-06-16 2020-02-04 Emd Millipore Corporation Methods for increasing the capacity of flow-through processes
CN110756051B (zh) 2014-06-25 2022-11-04 Emd 密理博公司 过滤器元件、切向流过滤系统、产生进料筛网的方法
KR102061553B1 (ko) 2014-08-29 2020-02-11 이엠디 밀리포어 코포레이션 잔류물의 재순환에 의한 싱글 패스 접선 유동 여과 시스템 및 접선 유동 여과 시스템을 사용하여 액체를 여과하는 공정
KR102079585B1 (ko) 2014-08-29 2020-02-21 이엠디 밀리포어 코포레이션 잔류물의 재순환을 이용한 싱글 패스 접선 유동 여과 시스템 및 접선 유동 여과 시스템
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JP6370853B2 (ja) * 2016-09-26 2018-08-08 インスティトゥト グリフォルス，ソシエダ アノニマ 免疫グロブリンの調製方法
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CN110590931B (zh) * 2019-09-05 2023-04-07 江苏康禾生物制药有限公司 去除和/或灭活重组人血小板生成因子原液中病毒的方法
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Also Published As

Publication number Publication date
CA2557229A1 (en) 2005-09-09
BRPI0508096A (pt) 2007-07-17
CN1922207B (zh) 2012-06-06
DK1718675T3 (da) 2013-07-15
BRPI0508096B8 (pt) 2021-05-25
US20070173638A1 (en) 2007-07-26
KR20060131920A (ko) 2006-12-20
US7553938B2 (en) 2009-06-30
RU2337109C2 (ru) 2008-10-27
WO2005082937A3 (en) 2005-11-17
ES2407380T5 (es) 2017-07-07
IL177541A (en) 2014-09-30
PT1718675E (pt) 2013-05-21
CN1922207A (zh) 2007-02-28
JP5042817B2 (ja) 2012-10-03
KR101206788B1 (ko) 2012-11-30
WO2005082937A2 (en) 2005-09-09
AU2005217148B2 (en) 2011-09-08
BRPI0508096B1 (pt) 2019-04-02
RU2006134285A (ru) 2008-04-10
JP2007533660A (ja) 2007-11-22
ES2407380T3 (es) 2013-06-12
PL1718675T3 (pl) 2013-09-30
ZA200607119B (en) 2007-04-25
AU2005217148A1 (en) 2005-09-09
UA87836C2 (ru) 2009-08-25
IL177541A0 (en) 2006-12-10
EP1718675A2 (en) 2006-11-08
EP1718675B2 (en) 2017-01-25
CA2557229C (en) 2012-07-10
EP1718675B1 (en) 2013-04-10
EP2277915A1 (en) 2011-01-26

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