NO20063405L - 2-(1H-indolylsulfanyl)-benzyl-aminderivater som SSRI - Google Patents

2-(1H-indolylsulfanyl)-benzyl-aminderivater som SSRI

Info

Publication number
NO20063405L
NO20063405L NO20063405A NO20063405A NO20063405L NO 20063405 L NO20063405 L NO 20063405L NO 20063405 A NO20063405 A NO 20063405A NO 20063405 A NO20063405 A NO 20063405A NO 20063405 L NO20063405 L NO 20063405L
Authority
NO
Norway
Prior art keywords
indolylsulfanyl
ssris
benzylamine derivatives
benzylamine
derivatives
Prior art date
Application number
NO20063405A
Other languages
English (en)
Other versions
NO336676B1 (no
Inventor
Jan Kehler
Morten Bang NØRGAARD
Karsten Juhl
Jimmy Sejberg
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2004/000894 external-priority patent/WO2005061455A1/en
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of NO20063405L publication Critical patent/NO20063405L/no
Publication of NO336676B1 publication Critical patent/NO336676B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20063405A 2003-12-23 2006-07-24 2-(1H-indolylsulfanyl)-benzyl-aminderivater som SSRI NO336676B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200301923 2003-12-23
PCT/DK2004/000894 WO2005061455A1 (en) 2003-12-23 2004-12-21 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri

Publications (2)

Publication Number Publication Date
NO20063405L true NO20063405L (no) 2006-07-24
NO336676B1 NO336676B1 (no) 2015-10-19

Family

ID=36603121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063405A NO336676B1 (no) 2003-12-23 2006-07-24 2-(1H-indolylsulfanyl)-benzyl-aminderivater som SSRI

Country Status (24)

Country Link
EP (1) EP1860100B1 (no)
KR (2) KR20080092471A (no)
CN (2) CN101372474A (no)
AR (1) AR046978A1 (no)
AT (1) ATE500220T1 (no)
CA (1) CA2551168C (no)
DE (1) DE602004031680D1 (no)
DK (1) DK1860100T3 (no)
EA (2) EA010666B1 (no)
ES (1) ES2362237T3 (no)
HK (1) HK1103075A1 (no)
IS (2) IS2551B (no)
ME (1) ME01040B (no)
MY (1) MY143038A (no)
NO (1) NO336676B1 (no)
NZ (1) NZ547046A (no)
PL (1) PL1860100T4 (no)
PT (1) PT1860100E (no)
RS (1) RS51899B (no)
SG (1) SG141463A1 (no)
SI (1) SI1860100T1 (no)
TW (1) TWI347183B (no)
UA (1) UA82920C2 (no)
ZA (1) ZA200705870B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101224201B (zh) * 2007-01-18 2011-10-05 和泓生物技术(上海)有限公司 多巴胺转运蛋白和去甲肾上腺素转运蛋白双重抑制剂的应用
JP2013536200A (ja) * 2010-08-20 2013-09-19 アミラ ファーマシューティカルス,インコーポレーテッド オートタキシン阻害剤およびその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803143A (en) 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
US4018830A (en) 1969-09-22 1977-04-19 Merck & Co., Inc. Phenylthioaralkylamines
US4055665A (en) 1974-11-25 1977-10-25 Merck & Co., Inc. Treating arrythmia with phenylthioaralkylamines
US4056632A (en) 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
EP0396827A1 (en) 1989-05-09 1990-11-14 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof
GB8912971D0 (en) 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
GB9126311D0 (en) 1991-12-11 1992-02-12 Wellcome Found Substituted diphenylsulfides
CZ293595A3 (cs) 1995-11-09 1999-12-15 Farmak A. S. Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích
US5912256A (en) * 1996-06-20 1999-06-15 Eli Lilly And Company Compounds having effects on serotonin-related systems
CA2264080A1 (en) * 1996-08-27 1998-03-05 Richard Eric Mewshaw 4-aminoethoxy indoles as dopamin d2 agonists and as 5ht1a ligands
DE69930381T2 (de) 1999-04-30 2006-12-07 Trustees Of The University Of Pennsylvania Spect abbildungsreagenzien für serotonintransporter
US6410736B1 (en) 1999-11-29 2002-06-25 Pfizer Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
US6436938B1 (en) 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KAREL SINDELAR ET AL.: "Potential Antidepressants and Inhibitors of 5-Hydroxytryptamine and Noradrenaline Re-uptake in the Brain: N,N-Dimethyl-(Arylthio)Thienylamines and N,N-Dimetyl-2-(Thienylthio)Benzylamines" COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATION, vol. 52, 1991, side 449-458, Dated: 01.01.0001 *

Also Published As

Publication number Publication date
NZ547046A (en) 2010-04-30
PL1860100T4 (pl) 2011-09-30
EP1860100A2 (en) 2007-11-28
HK1103075A1 (en) 2007-12-14
NO336676B1 (no) 2015-10-19
ES2362237T3 (es) 2011-06-30
IS2551B (is) 2009-10-15
IS8467A (is) 2006-05-15
EA010666B1 (ru) 2008-10-30
EP1860100A3 (en) 2007-12-05
CN100591666C (zh) 2010-02-24
EA200702258A1 (ru) 2008-02-28
RS51899B (en) 2012-02-29
AR046978A1 (es) 2006-01-04
DK1860100T3 (da) 2011-06-14
SG141463A1 (en) 2008-04-28
KR20060118529A (ko) 2006-11-23
TWI347183B (en) 2011-08-21
CA2551168A1 (en) 2005-07-07
TW200607499A (en) 2006-03-01
IS2815B (is) 2012-11-15
PT1860100E (pt) 2011-05-25
CN101372474A (zh) 2009-02-25
IS8827A (is) 2009-06-05
EA012752B1 (ru) 2009-12-30
ME01040B (me) 2010-05-07
SI1860100T1 (sl) 2011-06-30
KR20080092471A (ko) 2008-10-15
ZA200705870B (en) 2009-09-30
PL1860100T3 (pl) 2011-07-29
ATE500220T1 (de) 2011-03-15
MY143038A (en) 2011-02-28
EA200601226A1 (ru) 2006-10-27
UA82920C2 (en) 2008-05-26
EP1860100B1 (en) 2011-03-02
KR100872022B1 (ko) 2008-12-05
DE602004031680D1 (de) 2011-04-14
CA2551168C (en) 2011-09-13
CN1898204A (zh) 2007-01-17

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