NO20060319L - 3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon - Google Patents
3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjonInfo
- Publication number
- NO20060319L NO20060319L NO20060319A NO20060319A NO20060319L NO 20060319 L NO20060319 L NO 20060319L NO 20060319 A NO20060319 A NO 20060319A NO 20060319 A NO20060319 A NO 20060319A NO 20060319 L NO20060319 L NO 20060319L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- cell proliferation
- mediate
- methods
- inhibit cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49147403P | 2003-07-30 | 2003-07-30 | |
US49207303P | 2003-07-31 | 2003-07-31 | |
PCT/IB2004/002441 WO2005009997A1 (fr) | 2003-07-30 | 2004-07-19 | Composes d'indazole 3,5 disubstitutes, compositions pharmaceutiques, et procedes pour medier ou inhiber la proliferation cellulaire |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20060319L true NO20060319L (no) | 2006-02-24 |
Family
ID=34108010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20060319A NO20060319L (no) | 2003-07-30 | 2006-01-20 | 3,5-disubstituerte indazolforbindelser, farmasoytiske blandinger og fremgangsmater for a mediere eller inhibere celleproliferasjon |
Country Status (24)
Country | Link |
---|---|
US (2) | US7008953B2 (fr) |
EP (1) | EP1658284A1 (fr) |
JP (1) | JP3920914B2 (fr) |
KR (1) | KR20060030914A (fr) |
AR (1) | AR045143A1 (fr) |
AU (1) | AU2004259531A1 (fr) |
BR (1) | BRPI0413051A (fr) |
CA (1) | CA2532908A1 (fr) |
CO (1) | CO5650247A2 (fr) |
EA (1) | EA200600123A1 (fr) |
EC (1) | ECSP066335A (fr) |
IL (1) | IL172924A0 (fr) |
IS (1) | IS8214A (fr) |
MA (1) | MA27937A1 (fr) |
MX (1) | MXPA06001193A (fr) |
NL (1) | NL1026761C2 (fr) |
NO (1) | NO20060319L (fr) |
OA (1) | OA13196A (fr) |
PA (1) | PA8608201A1 (fr) |
PE (1) | PE20050330A1 (fr) |
TN (1) | TNSN06038A1 (fr) |
TW (1) | TW200521124A (fr) |
UY (1) | UY28442A1 (fr) |
WO (1) | WO2005009997A1 (fr) |
Families Citing this family (96)
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CA2561516A1 (fr) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Combinaisons d'inhibiteurs de transduction de signaux |
WO2006024945A1 (fr) * | 2004-09-03 | 2006-03-09 | Pfizer Inc. | Compositions pharmaceutiques contenant un inhibiteur des cdk |
US20060116519A1 (en) * | 2004-11-17 | 2006-06-01 | Agouron Pharmaceuticals, Inc. | Synthesis of 5-bromo-4-methyl-pyridin-3-ylmethyl)-ethyl-carbamic acid tert-butyl ester |
WO2006054143A1 (fr) * | 2004-11-17 | 2006-05-26 | Pfizer Inc. | Formes polymorphes de {5-[3-(4,6-difluoro-1h-benzimidazol-2-yl)-1h-indazol-5-yl]-4-methyl-pyridin-3-ylmethyl}-ethyl-amine |
CN100569464C (zh) | 2005-03-21 | 2009-12-16 | 皇家飞利浦电子股份有限公司 | 具有自动流体分配器的个人护理设备 |
US8252945B2 (en) * | 2005-04-13 | 2012-08-28 | Ube Industries, Ltd. | Protective agent for retinal neuronal cell comprising indazole derivative as active ingredient |
US7541367B2 (en) | 2005-05-31 | 2009-06-02 | Janssen Pharmaceutica, N.V. | 3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders |
JP2009523845A (ja) * | 2006-01-23 | 2009-06-25 | クリスタルゲノミクス インコーポレーテッド | たんぱく質キナーゼの活性を阻害するイミダゾピリジン誘導体、これの製造方法およびこれを含む薬学組成物 |
EP2046774A1 (fr) * | 2006-07-05 | 2009-04-15 | Pfizer Products Inc. | Dérivés de pyrazole utilisés en tant qu'inhibiteurs du cytochrome p450 |
AU2007283113A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
KR20100032886A (ko) * | 2007-06-08 | 2010-03-26 | 아보트 러보러터리즈 | 키나제 억제제로서의 5-헤테로아릴 치환된 인다졸 |
US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
US20090176778A1 (en) * | 2007-08-10 | 2009-07-09 | Franz Ulrich Schmitz | Certain nitrogen containing bicyclic chemical entities for treating viral infections |
EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
WO2009149837A1 (fr) * | 2008-06-09 | 2009-12-17 | Bayer Schering Pharma Aktiengesellschaft | 4-(indazolyl)-1,4-dihydropyridines substituées et leurs procédés d’utilisation |
UY31968A (es) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos |
WO2010036613A1 (fr) | 2008-09-26 | 2010-04-01 | Merck Sharp & Dohme Corp. | Nouveaux dérivés de benzimidazole cycliques utiles en tant qu'agents anti-diabétiques |
MX2011004258A (es) | 2008-10-22 | 2011-06-01 | Merck Sharp & Dohme | Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos. |
EP2362731B1 (fr) | 2008-10-31 | 2016-04-06 | Merck Sharp & Dohme Corp. | Nouveaux agents antidiabétiques utiles avec des dérivés de benzimidazole cycliques |
JP5743897B2 (ja) * | 2008-11-20 | 2015-07-01 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーGlaxoSmithKline LLC | 化合物 |
WO2010068601A1 (fr) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant |
CN102595900B (zh) | 2009-08-10 | 2015-07-15 | 萨穆梅德有限公司 | Wnt信号传导途径的吲唑抑制剂及其治疗用途 |
EP2464231A4 (fr) * | 2009-08-10 | 2013-02-06 | Samumed Llc | Indazoles utiles comme inhibiteurs de la voie de signalisation de wnt/bêta-caténine et utilisations thérapeutiques de ceux-ci |
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WO2011106273A1 (fr) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Nouveaux dérivés benzimidazole cycliques utiles comme agents antidiabétiques |
WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
EP2582709B1 (fr) | 2010-06-18 | 2018-01-24 | Sanofi | Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
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CA2819373A1 (fr) * | 2010-12-09 | 2012-06-14 | Amgen Inc. | Composes bicycliques en tant qu'inhibiteurs de pim |
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WO2012120058A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation |
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WO2012120051A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation |
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WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
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GB1376600A (en) | 1971-02-15 | 1974-12-04 | Agfa Gevaert | Photographic developer compositions |
FR2265739B1 (fr) | 1974-03-29 | 1976-12-17 | Ugine Kuhlmann | |
JPS5615287A (en) | 1979-07-16 | 1981-02-14 | Chugai Pharmaceut Co Ltd | Pyrazoloindazole derivative and its preparation |
JPS57109787A (en) | 1980-12-26 | 1982-07-08 | Chugai Pharmaceut Co Ltd | Pyrazoloindazole derivative |
JPS59228248A (ja) | 1983-06-08 | 1984-12-21 | Konishiroku Photo Ind Co Ltd | 直接ポジ用ハロゲン化銀写真感光材料 |
JPS604184A (ja) | 1983-06-23 | 1985-01-10 | Chugai Pharmaceut Co Ltd | ピラゾロインダゾ−ル誘導体 |
US4978603A (en) | 1987-12-14 | 1990-12-18 | Fuji Photo Film Co., Ltd. | Image forming process comprising developing fine grain silver halide emulsion with a hydroquinone developer |
EP0494774A1 (fr) | 1991-01-11 | 1992-07-15 | MERCK SHARP & DOHME LTD. | Composés hétéroaromatiques à 5 chaînons substitués par l'indazole |
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NZ243065A (en) | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
ZA951822B (en) | 1994-12-23 | 1996-09-26 | Glaxo Group Ltd | Chemical compounds |
DK0780386T3 (da) | 1995-12-20 | 2003-02-03 | Hoffmann La Roche | Matrixmetalloproteaseinhibitorer |
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HRP970371A2 (en) | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
WO1998043969A1 (fr) | 1997-03-31 | 1998-10-08 | Dupont Pharmaceuticals Company | Indazoles d'urees cycliques utiles comme inhibiteurs de vih protease |
FR2767475A1 (fr) | 1997-08-25 | 1999-02-26 | Oreal | Compositions de teinture des fibres keratiniques contenant des derives d'indazoles et procede |
EP1140183A1 (fr) | 1998-12-23 | 2001-10-10 | G.D. Searle & Co. | Techniques permettant d'utiliser un inhibiteur matriciel de la metalloproteinase et un antagoniste de l'integrine pour traiter les maladies neoplasiques |
GB2345486A (en) | 1999-01-11 | 2000-07-12 | Glaxo Group Ltd | Heteroaromatic protein tyrosine kinase inhibitors |
YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
KR100423899B1 (ko) | 2000-05-10 | 2004-03-24 | 주식회사 엘지생명과학 | 세포 증식 억제제로 유용한 1,1-디옥소이소티아졸리딘을갖는 인다졸 |
US6897231B2 (en) | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
WO2003004488A1 (fr) | 2001-07-03 | 2003-01-16 | Chiron Corporation | Composes d'indazole benzimidazole utilises comme inhibiteurs de tyrosine et de serine/threonine kinase |
FR2831536A1 (fr) | 2001-10-26 | 2003-05-02 | Aventis Pharma Sa | Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr |
US7008953B2 (en) * | 2003-07-30 | 2006-03-07 | Agouron Pharmaceuticals, Inc. | 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
-
2004
- 2004-06-10 US US10/866,059 patent/US7008953B2/en not_active Expired - Fee Related
- 2004-07-19 AU AU2004259531A patent/AU2004259531A1/en not_active Abandoned
- 2004-07-19 EA EA200600123A patent/EA200600123A1/ru unknown
- 2004-07-19 OA OA1200600024A patent/OA13196A/fr unknown
- 2004-07-19 MX MXPA06001193A patent/MXPA06001193A/es unknown
- 2004-07-19 WO PCT/IB2004/002441 patent/WO2005009997A1/fr not_active Application Discontinuation
- 2004-07-19 JP JP2006521699A patent/JP3920914B2/ja not_active Expired - Fee Related
- 2004-07-19 BR BRPI0413051-0A patent/BRPI0413051A/pt not_active IP Right Cessation
- 2004-07-19 EP EP04744094A patent/EP1658284A1/fr not_active Withdrawn
- 2004-07-19 KR KR1020067001916A patent/KR20060030914A/ko active IP Right Grant
- 2004-07-19 CA CA002532908A patent/CA2532908A1/fr not_active Abandoned
- 2004-07-23 PE PE2004000713A patent/PE20050330A1/es not_active Application Discontinuation
- 2004-07-27 UY UY28442A patent/UY28442A1/es not_active Application Discontinuation
- 2004-07-27 PA PA20048608201A patent/PA8608201A1/es unknown
- 2004-07-28 AR ARP040102681A patent/AR045143A1/es unknown
- 2004-07-29 TW TW093122761A patent/TW200521124A/zh unknown
- 2004-07-30 NL NL1026761A patent/NL1026761C2/nl not_active IP Right Cessation
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2005
- 2005-09-26 US US11/237,446 patent/US20060142345A1/en not_active Abandoned
- 2005-12-29 IL IL172924A patent/IL172924A0/en unknown
- 2005-12-29 CO CO05130968A patent/CO5650247A2/es not_active Application Discontinuation
- 2005-12-30 IS IS8214A patent/IS8214A/is unknown
-
2006
- 2006-01-20 NO NO20060319A patent/NO20060319L/no not_active Application Discontinuation
- 2006-01-30 EC EC2006006335A patent/ECSP066335A/es unknown
- 2006-01-30 MA MA28762A patent/MA27937A1/fr unknown
- 2006-01-30 TN TNP2006000038A patent/TNSN06038A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
JP3920914B2 (ja) | 2007-05-30 |
AR045143A1 (es) | 2005-10-19 |
US7008953B2 (en) | 2006-03-07 |
PA8608201A1 (es) | 2005-03-03 |
WO2005009997A1 (fr) | 2005-02-03 |
CO5650247A2 (es) | 2006-06-30 |
ECSP066335A (es) | 2006-07-28 |
AU2004259531A1 (en) | 2005-02-03 |
MA27937A1 (fr) | 2006-06-01 |
EP1658284A1 (fr) | 2006-05-24 |
TW200521124A (en) | 2005-07-01 |
US20060142345A1 (en) | 2006-06-29 |
EA200600123A1 (ru) | 2006-06-30 |
BRPI0413051A (pt) | 2006-10-17 |
UY28442A1 (es) | 2005-02-28 |
IL172924A0 (en) | 2006-06-11 |
PE20050330A1 (es) | 2005-05-16 |
MXPA06001193A (es) | 2006-04-11 |
NL1026761A1 (nl) | 2005-02-01 |
CA2532908A1 (fr) | 2005-02-03 |
OA13196A (en) | 2006-12-13 |
JP2007500183A (ja) | 2007-01-11 |
US20050026960A1 (en) | 2005-02-03 |
TNSN06038A1 (fr) | 2007-10-03 |
NL1026761C2 (nl) | 2005-10-18 |
KR20060030914A (ko) | 2006-04-11 |
IS8214A (is) | 2005-12-30 |
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