NO20053561L - Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorligander - Google Patents
Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorliganderInfo
- Publication number
- NO20053561L NO20053561L NO20053561A NO20053561A NO20053561L NO 20053561 L NO20053561 L NO 20053561L NO 20053561 A NO20053561 A NO 20053561A NO 20053561 A NO20053561 A NO 20053561A NO 20053561 L NO20053561 L NO 20053561L
- Authority
- NO
- Norway
- Prior art keywords
- receptor ligands
- glutamate receptor
- metabotrophic
- saturated
- quinoxaline derivatives
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 102000018899 Glutamate Receptors Human genes 0.000 title 1
- 108010027915 Glutamate Receptors Proteins 0.000 title 1
- 125000001567 quinoxalinyl group Chemical class N1=C(C=NC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000016193 Metabotropic glutamate receptors Human genes 0.000 abstract 1
- 108010010914 Metabotropic glutamate receptors Proteins 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44388903P | 2003-01-31 | 2003-01-31 | |
| US53063203P | 2003-12-19 | 2003-12-19 | |
| PCT/US2004/002131 WO2004069813A1 (en) | 2003-01-31 | 2004-01-26 | Saturated quinoxaline derivatives and their use as metabotropic glutamate receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20053561D0 NO20053561D0 (no) | 2005-07-20 |
| NO20053561L true NO20053561L (no) | 2005-10-28 |
Family
ID=32853344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20053561A NO20053561L (no) | 2003-01-31 | 2005-07-20 | Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorligander |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050004130A1 (ja) |
| EP (1) | EP1587796A1 (ja) |
| JP (1) | JP2006516628A (ja) |
| KR (1) | KR20060004907A (ja) |
| AU (1) | AU2004209540A1 (ja) |
| BR (1) | BRPI0406810A (ja) |
| CA (1) | CA2513824A1 (ja) |
| MX (1) | MXPA05008186A (ja) |
| NO (1) | NO20053561L (ja) |
| WO (1) | WO2004069813A1 (ja) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0303492D0 (sv) * | 2003-12-19 | 2003-12-19 | Astrazeneca Ab | New use VII |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007104035A1 (en) * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| EP2068872A1 (en) * | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| AU2007299920A1 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | PPAR Mediated Modulation of Neurogenesis |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4709052A (en) * | 1983-05-31 | 1987-11-24 | Sumitomo Chemical Company, Limited | Soil disease-controlling imides |
| JPS59227845A (ja) * | 1983-06-09 | 1984-12-21 | Sumitomo Chem Co Ltd | 酸アミド系化合物 |
| JPS6041602A (ja) * | 1983-08-17 | 1985-03-05 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS59231068A (ja) * | 1983-06-13 | 1984-12-25 | Sumitomo Chem Co Ltd | 酸イミド系化合物およびその製造法 |
| JPS59222403A (ja) * | 1983-05-31 | 1984-12-14 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS59225101A (ja) * | 1983-06-03 | 1984-12-18 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS6042303A (ja) * | 1983-08-18 | 1985-03-06 | Sumitomo Chem Co Ltd | シアノアセトアニリド誘導体を有効成分とする植物病害防除剤 |
| DD220602A1 (de) * | 1983-09-13 | 1985-04-03 | Fahlberg List Veb | Verfahren zur herstellung von chinoxalin-2-thiocarbonsaeureamiden |
| JPS60214706A (ja) * | 1984-04-05 | 1985-10-28 | Sumitomo Chem Co Ltd | 土壌病害防除剤 |
| JPS60224663A (ja) * | 1984-04-23 | 1985-11-09 | Sumitomo Chem Co Ltd | 酸アミド系化合物 |
| JP2759257B2 (ja) * | 1993-09-28 | 1998-05-28 | 大塚製薬株式会社 | 糖尿病治療剤 |
| JP3964478B2 (ja) * | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| US6429207B1 (en) * | 1997-11-21 | 2002-08-06 | Nps Pharmaceuticals, Inc. | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases |
| JP2001524468A (ja) * | 1997-11-21 | 2001-12-04 | エヌピーエス ファーマシューティカルズ インコーポレーテッド | 中枢神経系疾患を治療するための代謝調節型グルタミン酸受容体アンタゴニスト |
| CN1361768A (zh) * | 1999-06-02 | 2002-07-31 | Nps药物有限公司 | 代谢移变的谷氨酸盐受体拮抗剂和它们治疗中枢神经系统疾病的用途 |
| PL206415B1 (pl) * | 1999-07-20 | 2010-08-31 | Dow Agrosciences Llc | Heterocykliczny amid aromatyczny, kompozycja grzybobójcza heterocyklicznego amidu aromatycznego oraz sposób zwalczania lub zapobiegania zakażeniom grzybami |
| CZ2002487A3 (cs) * | 1999-08-20 | 2002-06-12 | Dow Agrosciences Llc | Fungicidní heterocyklické aromatické amidy, prostředky na jejich bázi, způsoby jejich pouľití a přípravy |
-
2004
- 2004-01-26 EP EP04705287A patent/EP1587796A1/en not_active Withdrawn
- 2004-01-26 WO PCT/US2004/002131 patent/WO2004069813A1/en active Application Filing
- 2004-01-26 BR BR0406810-6A patent/BRPI0406810A/pt not_active IP Right Cessation
- 2004-01-26 KR KR1020057013475A patent/KR20060004907A/ko not_active Application Discontinuation
- 2004-01-26 AU AU2004209540A patent/AU2004209540A1/en not_active Abandoned
- 2004-01-26 JP JP2006503034A patent/JP2006516628A/ja active Pending
- 2004-01-26 CA CA002513824A patent/CA2513824A1/en not_active Abandoned
- 2004-01-26 MX MXPA05008186A patent/MXPA05008186A/es not_active Application Discontinuation
- 2004-01-30 US US10/766,948 patent/US20050004130A1/en not_active Abandoned
-
2005
- 2005-07-20 NO NO20053561A patent/NO20053561L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1587796A1 (en) | 2005-10-26 |
| CA2513824A1 (en) | 2004-08-19 |
| WO2004069813A1 (en) | 2004-08-19 |
| KR20060004907A (ko) | 2006-01-16 |
| US20050004130A1 (en) | 2005-01-06 |
| AU2004209540A1 (en) | 2004-08-19 |
| BRPI0406810A (pt) | 2005-12-27 |
| MXPA05008186A (es) | 2005-10-05 |
| JP2006516628A (ja) | 2006-07-06 |
| NO20053561D0 (no) | 2005-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20053561L (no) | Mettede kinoksalinderivater og deres anvendelse som metabotrofe og glutamatreseptorligander | |
| NO20063470L (no) | Tetrazolforbindelser og deres anvendelse av metabotrofe glutamatreseptorantagonister | |
| NO20055977L (no) | Nye benzimidazolderivater | |
| NO20073663L (no) | Tiazol-4-karboksamid-derivater som mGluR5 antagonister | |
| NO20063469L (no) | Polyeheterosykliske forbindelser og deres anvendelse som metabotrofe glutamat reseptorantagonister | |
| NO20066055L (no) | Pyridinderivater | |
| NO20075624L (no) | Nye histamin H3-reseptorligander og deres terapeutiske anvendelser | |
| NO20076479L (no) | Nye oksadiazolderivater og anvendelse derav som positive allosteriske metabotropiske modulatorer av glutamatreseptorer | |
| NO20071642L (no) | N-Benzensulfonylsubstituerte anilino-pyrimidinanaloger | |
| DK1716152T3 (da) | Kondenserade heterocykliske forbindelser og deres anvendelse som metabotrope receptorantagonister til behandling af gastrointentinde lidelser | |
| NO20083684L (no) | Laktam-inneholdende forbindelser og derivater derav som faktor XA-inhibitorer | |
| NO20082496L (no) | Pyrazinderivater | |
| NO20074275L (no) | 2- (4-okso-4H-kinazolin-3-yl) acetamider og deres anvendelse som Vasopressin-V3-antagonister | |
| NO20062021L (no) | Omleirede pentanoler, fremgangsmpte for fremstilling av dette, og deres anvendelse som antiflogistika | |
| NO20054905L (no) | 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika | |
| NO20063597L (no) | Acetylinske piperazinforbindelser og deres anvendelse som metabotrofiske glutamatreseptorantagonister | |
| NO20070249L (no) | Pyrrazolo-pyrimidin derivater | |
| NO20070606L (no) | Inhibitorer av IAP | |
| NO20082629L (no) | Macrocyklisk factor VIIa-inhibitorer anvendbare som antikoagulanter | |
| NO20051826L (no) | Heterosyklisk substituerte piperaziner for behandling av schizofreni | |
| NO20070258L (no) | Benzyltriazolonforbindelser som ikke-nukleoside revers transkriptase inhibitorer | |
| NO20081217L (no) | Nye benzotiazolonderivater | |
| ATE387199T1 (de) | Neue substanzen und verbindungen als protease- inhibitoren | |
| NO20062370L (no) | Amidderivater | |
| TW200732313A (en) | Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |