NO20051155L - Fremgangsmate for fremstilling av en farmasoytisk aktiv forbindelse - Google Patents

Fremgangsmate for fremstilling av en farmasoytisk aktiv forbindelse

Info

Publication number
NO20051155L
NO20051155L NO20051155A NO20051155A NO20051155L NO 20051155 L NO20051155 L NO 20051155L NO 20051155 A NO20051155 A NO 20051155A NO 20051155 A NO20051155 A NO 20051155A NO 20051155 L NO20051155 L NO 20051155L
Authority
NO
Norway
Prior art keywords
give
rizatriptan
reaction
preparation
hydrazone
Prior art date
Application number
NO20051155A
Other languages
English (en)
Norwegian (no)
Inventor
Pere Dalmases Barjoan
Montserrat Armengol Asparo
Original Assignee
Vita Cientifica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Cientifica Srl filed Critical Vita Cientifica Srl
Publication of NO20051155L publication Critical patent/NO20051155L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20051155A 2002-08-07 2005-03-03 Fremgangsmate for fremstilling av en farmasoytisk aktiv forbindelse NO20051155L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201874A ES2204303B2 (es) 2002-08-07 2002-08-07 Procedimiento para la obtencion de un compuesto farmaceuticamente activo.
PCT/IB2003/003540 WO2004014877A1 (en) 2002-08-07 2003-08-05 Process for preparing rizatriptan

Publications (1)

Publication Number Publication Date
NO20051155L true NO20051155L (no) 2005-03-03

Family

ID=31502894

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051155A NO20051155L (no) 2002-08-07 2005-03-03 Fremgangsmate for fremstilling av en farmasoytisk aktiv forbindelse

Country Status (11)

Country Link
US (1) US7279581B2 (de)
EP (1) EP1527053B8 (de)
KR (1) KR20050039749A (de)
AT (1) ATE312084T1 (de)
AU (1) AU2003250478A1 (de)
DE (1) DE60302671D1 (de)
ES (2) ES2204303B2 (de)
IS (1) IS7702A (de)
NO (1) NO20051155L (de)
TW (1) TW200404798A (de)
WO (1) WO2004014877A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103288714A (zh) * 2002-06-27 2013-09-11 史密斯克莱.比奇曼(科克)有限公司 卡维地洛磷酸盐和/或其溶剂合物相应的组合物和/或治疗方法
ES2204302B2 (es) * 2002-08-07 2005-03-01 Laboratorios Vita, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo.
WO2005068453A2 (en) 2004-01-09 2005-07-28 Ratiopharm Gmbh Crystalline forms of rizatriptan benzoate
ATE461916T1 (de) * 2004-01-28 2010-04-15 Ratiopharm Gmbh Syntheseverfahren und zwischenprodukte zur herstellung von rizatriptan
EP1951713A1 (de) * 2005-11-14 2008-08-06 Matrix Laboratories Ltd Verfahren zur herstellung von rizatriptanbenzoat im grossmasstab
ATE510836T1 (de) * 2006-01-19 2011-06-15 Matrix Lab Ltd Umwandlung eines aromatischen diazoniumsalzes in ein arylhydrazin
EP3407869A1 (de) 2016-01-27 2018-12-05 Instar Technologies A.S. Oromucosale nanofaserträger zur therapeutischen behandlung
CN115353492A (zh) * 2022-08-26 2022-11-18 浙江野风药业股份有限公司 一种连续合成1-(4-肼基苯基)甲基-1,2,4-三氮唑的方法
CN115417859B (zh) * 2022-09-19 2024-02-02 陕西师范大学 一种苯甲酸利扎曲坦的合成方法
CN116283924A (zh) * 2023-01-16 2023-06-23 四川效佳科技有限公司 一种药用级纯度的苯甲酸利扎曲普坦的重结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
ES2033578B1 (es) * 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida.
ES2033577B1 (es) 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de la 2-carboxi-3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida y sus esteres alquilicos inferiores.
GB9215526D0 (en) * 1992-07-22 1992-09-02 Merck Sharp & Dohme Chemical process
US5567824A (en) * 1994-05-24 1996-10-22 Merck & Co., Inc. Palladium catalyzed ring closure of triazolyltryptamine
CN1084751C (zh) 1996-08-13 2002-05-15 麦克公司 钯催化的吲哚化反应
US5998438A (en) * 1996-11-26 1999-12-07 Allelix Biopharmaceuticals, Inc. 5-cyclo indole compounds
GB9926250D0 (en) * 1999-11-06 2000-01-12 Knoll Ag Chemical process

Also Published As

Publication number Publication date
AU2003250478A1 (en) 2004-02-25
TW200404798A (en) 2004-04-01
DE60302671D1 (de) 2006-01-12
ES2204303B2 (es) 2004-12-16
KR20050039749A (ko) 2005-04-29
EP1527053B1 (de) 2005-12-07
US20050148778A1 (en) 2005-07-07
EP1527053B8 (de) 2006-03-08
WO2004014877A1 (en) 2004-02-19
ATE312084T1 (de) 2005-12-15
ES2254982T3 (es) 2006-06-16
EP1527053A1 (de) 2005-05-04
US7279581B2 (en) 2007-10-09
IS7702A (is) 2005-02-21
ES2204303A1 (es) 2004-04-16

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