NO20045217L - Anvendelse av tio-oxindolderivater for behandling av hormon relaterte tilstander - Google Patents

Anvendelse av tio-oxindolderivater for behandling av hormon relaterte tilstander

Info

Publication number
NO20045217L
NO20045217L NO20045217A NO20045217A NO20045217L NO 20045217 L NO20045217 L NO 20045217L NO 20045217 A NO20045217 A NO 20045217A NO 20045217 A NO20045217 A NO 20045217A NO 20045217 L NO20045217 L NO 20045217L
Authority
NO
Norway
Prior art keywords
treatment
formula
thio
hormone
delivery
Prior art date
Application number
NO20045217A
Other languages
English (en)
Inventor
Andrew Fensome
Diane Deborah Harrison
Richard Craig Winneker
Gary Grubb
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20045217L publication Critical patent/NO20045217L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Abstract

Foreliggende oppfinnelse tilveiebringer metoder som gir prevensjon som omfatter levering til en kvinne av et preparat inneholdende en forbindelse med formel I eller tautomerer derav, i et regime som involverer levering av én eller flere av en selektiv østrogenreseptor-modulator, hvor formel I er: og hvor R1-R5 og Q1er definert som beskrevet her. Metoder for å gi hormonerstatningsterapi og for behandling av karsinomer, dysfunksjonell blødning, uterin leiomyomata, endometriose og polycystisk eggstokk-syndrom er gitt som omfatter levering av en forbindelse med formel I, og en selektiv østrogenreseptormodulator er også beskrevet.
NO20045217A 2002-06-25 2004-11-29 Anvendelse av tio-oxindolderivater for behandling av hormon relaterte tilstander NO20045217L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39182602P 2002-06-25 2002-06-25
PCT/US2003/019710 WO2004000225A2 (en) 2002-06-25 2003-06-23 Use of thio-oxindole derivatives in treatment of hormone-related conditions

Publications (1)

Publication Number Publication Date
NO20045217L true NO20045217L (no) 2005-03-15

Family

ID=30000758

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045217A NO20045217L (no) 2002-06-25 2004-11-29 Anvendelse av tio-oxindolderivater for behandling av hormon relaterte tilstander

Country Status (17)

Country Link
US (3) US7488734B2 (no)
EP (1) EP1531806A4 (no)
JP (1) JP2005535623A (no)
CN (1) CN1662234A (no)
AR (1) AR040339A1 (no)
AU (1) AU2003245637A1 (no)
BR (1) BR0312054A (no)
CA (1) CA2489813A1 (no)
CR (1) CR7610A (no)
EC (1) ECSP055574A (no)
IL (1) IL165395A0 (no)
MX (1) MXPA04012419A (no)
NO (1) NO20045217L (no)
RU (1) RU2005101635A (no)
TW (1) TW200407124A (no)
WO (1) WO2004000225A2 (no)
ZA (1) ZA200410409B (no)

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US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6407101B1 (en) * 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6509334B1 (en) * 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6391907B1 (en) * 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
MXPA04012419A (es) * 2002-06-25 2005-04-19 Wyeth Corp Uso de derivados de tio-oxindol en el tratamiento de condiciones relacionadas con la hormona.
SG151331A1 (en) * 2004-04-07 2009-04-30 Wyeth Corp Crystalline polymorph of a bazedoxifene acetate
JP2007532548A (ja) * 2004-04-07 2007-11-15 ワイス バゼドキシフェンアセテートの結晶質多形体
BRPI0509213A (pt) * 2004-04-08 2007-08-28 Wyeth Corp método para previnir, reduzir ou minimizar a formação de impurezas de tioamida durante a tionação de um composto de carbonila, produto, e, uso de um agente extrator
ATE413398T1 (de) 2004-04-08 2008-11-15 Wyeth Corp Thioamidderivate als progesteronrezeptormodulatoren
US7556150B2 (en) * 2004-06-07 2009-07-07 Duramed Pharmaceuticals, Inc. Dispenser for progestin used for acute and maintenance treatment of DUB
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
MY145694A (en) 2005-04-11 2012-03-30 Xenon Pharmaceuticals Inc Spiroheterocyclic compounds and their uses as therapeutic agents
MY144968A (en) 2005-04-11 2011-11-30 Xenon Pharmaceuticals Inc Spiro-oxindole compounds and their uses as therapeutic agents
WO2008060789A2 (en) 2006-10-12 2008-05-22 Xenon Pharmaceuticals Inc. Use of spiro-oxindole compounds as therapeutic agents
CA2710293A1 (en) * 2007-12-20 2009-07-02 Teva Women's Health, Inc. Dosage regimens and pharmaceutical compositions and packages for emergency contraception
SG10201703086VA (en) 2008-10-17 2017-05-30 Xenon Pharmaceuticals Inc Spiro-oxindole compounds and their use as therapeutic agents
EP2350091B1 (en) 2008-10-17 2015-06-03 Xenon Pharmaceuticals Inc. Spiro-oxindole compounds and their use as therapeutic agents
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
WO2011029782A1 (en) * 2009-09-11 2011-03-17 Bayer Schering Pharma Aktiengesellschaft Substituted (heteroarylmethyl) thiohydantoins as anticancer drugs
RU2544852C2 (ru) 2009-10-14 2015-03-20 Ксенон Фармасьютикалз Инк. Способы синтеза спиро-оксиндольных соединений
US9504671B2 (en) 2010-02-26 2016-11-29 Xenon Pharmaceuticals Inc. Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
CN102939287B (zh) 2010-06-10 2016-01-27 塞拉根制药公司 雌激素受体调节剂及其用途
US9193714B2 (en) 2011-12-14 2015-11-24 Seragon Pharmaceuticals, Inc. Fluorinated estrogen receptor modulators and uses thereof
TW201636017A (zh) 2015-02-05 2016-10-16 梯瓦製藥國際有限責任公司 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法

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US5461065A (en) * 1993-10-15 1995-10-24 Eli Lilly And Company Methods for inhibiting endometriosis
DE4335876A1 (de) * 1993-10-17 1995-04-20 Schering Ag Kombination von Progesteronantagonisten und Antiöstrogenen mit partialer agonistischer Wirkung für die Hormonsubstitutions-Therapie für peri- und postmenopausale Frauen
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KR20050013627A (ko) 2002-06-25 2005-02-04 와이어쓰 Ｐｒ 조절제로서의 사이클로티오카바메이트 유도체 및피부 질환을 치료하기 위한 이의 용도
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Also Published As

Publication number Publication date
US8242098B2 (en) 2012-08-14
TW200407124A (en) 2004-05-16
ECSP055574A (es) 2005-04-18
EP1531806A2 (en) 2005-05-25
BR0312054A (pt) 2005-10-18
WO2004000225A3 (en) 2004-06-10
EP1531806A4 (en) 2005-09-21
AU2003245637A1 (en) 2004-01-06
MXPA04012419A (es) 2005-04-19
JP2005535623A (ja) 2005-11-24
CR7610A (es) 2006-05-29
US7488734B2 (en) 2009-02-10
CN1662234A (zh) 2005-08-31
US20090099223A1 (en) 2009-04-16
WO2004000225A2 (en) 2003-12-31
CA2489813A1 (en) 2003-12-31
AR040339A1 (es) 2005-03-30
IL165395A0 (en) 2006-01-15
RU2005101635A (ru) 2005-08-10
ZA200410409B (en) 2006-05-31
US20120220558A1 (en) 2012-08-30
US20040002535A1 (en) 2004-01-01

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