IL165395A0 - Use of thio-oxubdile derivatives in treatment of hormone-related conditions - Google Patents

Use of thio-oxubdile derivatives in treatment of hormone-related conditions

Info

Publication number
IL165395A0
IL165395A0 IL16539503A IL16539503A IL165395A0 IL 165395 A0 IL165395 A0 IL 165395A0 IL 16539503 A IL16539503 A IL 16539503A IL 16539503 A IL16539503 A IL 16539503A IL 165395 A0 IL165395 A0 IL 165395A0
Authority
IL
Israel
Prior art keywords
oxubdile
thio
hormone
derivatives
treatment
Prior art date
Application number
IL16539503A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of IL165395A0 publication Critical patent/IL165395A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16539503A 2002-06-25 2003-06-23 Use of thio-oxubdile derivatives in treatment of hormone-related conditions IL165395A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39182602P 2002-06-25 2002-06-25
PCT/US2003/019710 WO2004000225A2 (en) 2002-06-25 2003-06-23 Use of thio-oxindole derivatives in treatment of hormone-related conditions

Publications (1)

Publication Number Publication Date
IL165395A0 true IL165395A0 (en) 2006-01-15

Family

ID=30000758

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16539503A IL165395A0 (en) 2002-06-25 2003-06-23 Use of thio-oxubdile derivatives in treatment of hormone-related conditions

Country Status (17)

Country Link
US (3) US7488734B2 (no)
EP (1) EP1531806A4 (no)
JP (1) JP2005535623A (no)
CN (1) CN1662234A (no)
AR (1) AR040339A1 (no)
AU (1) AU2003245637A1 (no)
BR (1) BR0312054A (no)
CA (1) CA2489813A1 (no)
CR (1) CR7610A (no)
EC (1) ECSP055574A (no)
IL (1) IL165395A0 (no)
MX (1) MXPA04012419A (no)
NO (1) NO20045217L (no)
RU (1) RU2005101635A (no)
TW (1) TW200407124A (no)
WO (1) WO2004000225A2 (no)
ZA (1) ZA200410409B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6509334B1 (en) * 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6355648B1 (en) * 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
BR0312054A (pt) * 2002-06-25 2005-10-18 Wyeth Corp Uso de derivados de tio-oxindol na preparação de medicamentos úteis no tratamento de condições relacionadas com hormÈnio, e kit farmacêutico
PA8629201A1 (es) * 2004-04-07 2005-11-25 Wyeth Corp Polimorfo cristalino de acetato de bazedoxifeno
JP2007532560A (ja) * 2004-04-07 2007-11-15 ワイス バゼドキシフェンアセテートの結晶多形
DE602005010065D1 (de) * 2004-04-08 2008-11-13 Wyeth Corp Verfahren zur minimierung von thioamidverunreinigungen
CN100522960C (zh) * 2004-04-08 2009-08-05 惠氏公司 作为黄体酮受体调节剂的硫代酰胺衍生物
WO2005120432A1 (en) * 2004-06-07 2005-12-22 Duramed Pharmaceuticals, Inc. Dispenser for progestin used for acute and maintenance treatment of dub
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
AR056968A1 (es) 2005-04-11 2007-11-07 Xenon Pharmaceuticals Inc Compuestos espiro-oxindol y composiciones farmacéuticas
AR053710A1 (es) 2005-04-11 2007-05-16 Xenon Pharmaceuticals Inc Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
TW200833695A (en) 2006-10-12 2008-08-16 Xenon Pharmaceuticals Inc Use of spiro-oxindole compounds as therapeutic agents
JP2011507853A (ja) * 2007-12-20 2011-03-10 テバ ウィメンズ ヘルス インコーポレイテッド 緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ
RU2011119626A (ru) 2008-10-17 2012-11-27 Ксенон Фармасьютикалз Инк. Спирооксиндольные соединения и их применение в качестве терапевтичеких средств
US8101647B2 (en) 2008-10-17 2012-01-24 Xenon Pharmaceuticals Inc. Spiro-oxindole compounds and their use as therapeutic agents
AR077252A1 (es) 2009-06-29 2011-08-10 Xenon Pharmaceuticals Inc Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
WO2011029782A1 (en) * 2009-09-11 2011-03-17 Bayer Schering Pharma Aktiengesellschaft Substituted (heteroarylmethyl) thiohydantoins as anticancer drugs
EP2488531B1 (en) 2009-10-14 2014-03-26 Xenon Pharmaceuticals Inc. Synthetic methods for spiro-oxindole compounds
WO2011106729A2 (en) 2010-02-26 2011-09-01 Xenon Pharmaceuticals Inc. Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
ES2627692T3 (es) 2010-06-10 2017-07-31 Aragon Pharmaceuticals, Inc. Moduladores de receptores de estrógenos y usos de los mismos
CA2857057A1 (en) 2011-12-14 2013-06-20 Seragon Pharmaceuticals, Inc. Fluorinated estrogen receptor modulators and uses thereof
WO2016127068A1 (en) 2015-02-05 2016-08-11 Teva Pharmaceuticals International Gmbh Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5461065A (en) * 1993-10-15 1995-10-24 Eli Lilly And Company Methods for inhibiting endometriosis
DE4335876A1 (de) * 1993-10-17 1995-04-20 Schering Ag Kombination von Progesteronantagonisten und Antiöstrogenen mit partialer agonistischer Wirkung für die Hormonsubstitutions-Therapie für peri- und postmenopausale Frauen
US5446053A (en) * 1993-12-21 1995-08-29 Eli Lilly And Company Methods of inhibiting dysfunctional uterine bleeding
US5633011A (en) * 1994-08-04 1997-05-27 Alza Corporation Progesterone replacement therapy
US6653297B1 (en) * 1997-07-03 2003-11-25 Medical College Of Hampton Roads Control of selective estrogen receptor modulators
US6326392B1 (en) 1997-11-06 2001-12-04 American Home Products Corporation Anti-estrogen plus progestin containing oral contraceptives
WO2000024366A1 (de) 1998-10-23 2000-05-04 Aventis Pharma Deutschland Gmbh Zubereitungen zur topischen applikation von antiandrogen wirksamen substanzen
US6331562B1 (en) * 1998-12-30 2001-12-18 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
BR9916735A (pt) 1998-12-31 2001-09-25 Sugen Inc Compostos de 3-heteroarilidenil-2-indolinona para a modulação da atividade das cinases protéicas e para uso na quimioterapia do cancêr
US6391907B1 (en) * 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
JP2003525796A (ja) 1999-08-26 2003-09-02 オートモーティブ システムズ ラボラトリー インコーポレーテッド 磁気センサ
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
US20010034340A1 (en) * 2000-03-20 2001-10-25 American Home Products Corporation Hormone replacement therapy
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
CA2420289A1 (en) * 2000-08-23 2002-02-28 Akzo Nobel N.V. 10-aryl-11-hbenzo [b]fluorene derivatives and analogs for medicinal use
CN1665510A (zh) * 2002-06-25 2005-09-07 惠氏公司 作为pr调节剂的环硫代氨基甲酸酯衍生物的衍生物和其用于治疗皮肤病的用途
CN1662241A (zh) * 2002-06-25 2005-08-31 惠氏公司 环硫代氨基甲酸酯衍生物在治疗与激素有关的病症中的用途
BR0312054A (pt) * 2002-06-25 2005-10-18 Wyeth Corp Uso de derivados de tio-oxindol na preparação de medicamentos úteis no tratamento de condições relacionadas com hormÈnio, e kit farmacêutico
MXPA04012418A (es) * 2002-06-25 2005-04-19 Wyeth Corp Uso de derivados de tio-oxindol en tratamiento de trastornos de la piel.

Also Published As

Publication number Publication date
JP2005535623A (ja) 2005-11-24
CA2489813A1 (en) 2003-12-31
CR7610A (es) 2006-05-29
EP1531806A4 (en) 2005-09-21
US20090099223A1 (en) 2009-04-16
TW200407124A (en) 2004-05-16
US20120220558A1 (en) 2012-08-30
WO2004000225A3 (en) 2004-06-10
CN1662234A (zh) 2005-08-31
ZA200410409B (en) 2006-05-31
EP1531806A2 (en) 2005-05-25
MXPA04012419A (es) 2005-04-19
US8242098B2 (en) 2012-08-14
AR040339A1 (es) 2005-03-30
RU2005101635A (ru) 2005-08-10
AU2003245637A1 (en) 2004-01-06
US20040002535A1 (en) 2004-01-01
US7488734B2 (en) 2009-02-10
BR0312054A (pt) 2005-10-18
NO20045217L (no) 2005-03-15
WO2004000225A2 (en) 2003-12-31
ECSP055574A (es) 2005-04-18

Similar Documents

Publication Publication Date Title
EP1515725A4 (en) USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN THE TREATMENT OF HORMONE-RELATED ILLNESSES
IL165395A0 (en) Use of thio-oxubdile derivatives in treatment of hormone-related conditions
EP1465615A4 (en) TRICYCLIC BISENONE DERIVATIVES AND METHODS OF USE
AU2003217870A8 (en) Pini-modulating compounds and methods of use thereof
IL218909A0 (en) Treatment of diabetes
AU2003213673A8 (en) Pin1-modulating compounds and methods of use thereof
IL209352A0 (en) 4-tetrazolyl-4phenylpiperidine derivatives for treating pain
PL372814A1 (en) Thiazolidine-4-carbonitriles and analogues and their use as dipeptidyl-peptidas inhibitors
PL377791A1 (pl) Pochodne 3-aminopiperydyny i sposoby ich wytwarzania
HK1087103A1 (en) Anilinopyrazole derivatives useful for the treatment of diabetes
AU2003279442A8 (en) 2-thiohydantoine derivative compounds and use thereof for the treatment of diabetes
IL165394A0 (en) Use of thio-oxindole derivatives in treatment of skin disorders
EP1625111A4 (en) THYRONAMINE DERIVATIVES AND ANALOGUES AND METHODS OF USE THEREOF
EP1476150A4 (en) CARBOXY FULLERES AND USE METHOD THEREFOR
IL163868A0 (en) Hermiasterlin derivatives and uses thereof
AU2003297612A8 (en) 2-substituted-3-propenamide derivatives and methods of using the same
EP1545287A4 (en) VASOREGULATORY COMPOUNDS AND METHODS RELATING TO THEIR USE
SG110107A1 (en) Compound and use in treatment
EP1467673A4 (en) IRRIGATION SOLUTION AND METHODS OF USE
AU2003283938A1 (en) Use of certain compounds in treatment of obesity
AU2003279800A8 (en) Sulfatases and methods of use thereof
SI1680405T1 (sl) Bengamidni derivati in njihova uporaba za zdravljenje rakavih bolezni
GB0221712D0 (en) Methods of treatment
ZA200605302B (en) Use of pentadienoic acid derivatives for the treatment of hyperuricemia
EP1569928A4 (en) THERAPEUTIC COMPOUNDS AND METHOD