MX2009009514A - Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona. - Google Patents

Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona.

Info

Publication number
MX2009009514A
MX2009009514A MX2009009514A MX2009009514A MX2009009514A MX 2009009514 A MX2009009514 A MX 2009009514A MX 2009009514 A MX2009009514 A MX 2009009514A MX 2009009514 A MX2009009514 A MX 2009009514A MX 2009009514 A MX2009009514 A MX 2009009514A
Authority
MX
Mexico
Prior art keywords
sulfonylated
modulation
progesterone receptor
compounds
heterocycles useful
Prior art date
Application number
MX2009009514A
Other languages
English (en)
Inventor
Andrew Fensome
Casey Cameron Mccomas
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MX2009009514A publication Critical patent/MX2009009514A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Se proveen compuestos de la siguiente estructura, (ver fórmula I) en donde R1-R4 y R6-R9 se definen posteriormente, como son métodos de preparación y usando estos compuestos para anticoncepción; tratamiento o prevención de fibroides; Ieiomioma uterino; endometriosis, sangrado disfuncional, síndrome de ovario policístico; y carcinomas dependientes de hormona, proveer terapia de reemplazo de hormona; estimulación de consumo de alimentos; sincronización de estro, y tratamiento de síntomas relacionados con el ciclo.
MX2009009514A 2007-03-06 2008-03-04 Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona. MX2009009514A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90519907P 2007-03-06 2007-03-06
PCT/US2008/002830 WO2008109056A1 (en) 2007-03-06 2008-03-04 Sulfonylated heterocycles useful for modulation of the progesterone receptor

Publications (1)

Publication Number Publication Date
MX2009009514A true MX2009009514A (es) 2009-09-16

Family

ID=39524346

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009009514A MX2009009514A (es) 2007-03-06 2008-03-04 Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona.

Country Status (10)

Country Link
US (2) US7750038B2 (es)
EP (1) EP2121657A1 (es)
JP (1) JP2010520283A (es)
AR (1) AR065521A1 (es)
CA (1) CA2679380A1 (es)
CL (1) CL2008000675A1 (es)
MX (1) MX2009009514A (es)
PA (1) PA8771801A1 (es)
TW (1) TW200848021A (es)
WO (1) WO2008109056A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200848019A (en) * 2007-03-06 2008-12-16 Wyeth Corp Aryl sulfonamides useful for modulation of the progesterone receptor
US8038364B2 (en) 2007-08-07 2011-10-18 Saint-Gobain Technical Fabrics America, Inc. Reinforcement for asphaltic paving, method of paving, and process for making a grid with the coating for asphaltic paving
JP2009286773A (ja) * 2008-03-14 2009-12-10 Bayer Cropscience Ag 殺虫性縮環式アリール類
CN104884250B (zh) 2012-10-19 2018-05-04 加拿大圣戈班爱德福思有限公司 复合粘着膜
WO2015074064A2 (en) 2013-11-18 2015-05-21 Bair Kenneth W Tetrahydroquinoline compositions as bet bromodomain inhibitors
EP3071205B1 (en) 2013-11-18 2020-02-05 Forma Therapeutics, Inc. Benzopiperazine compositions as bet bromodomain inhibitors

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW263508B (es) 1991-02-12 1995-11-21 Pfizer
DE19633751A1 (de) 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Arylpyridine
US6391907B1 (en) * 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6509334B1 (en) * 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6358948B1 (en) * 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6417214B1 (en) * 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
AU5570900A (en) 1999-07-01 2001-01-22 Sankyo Company Limited Indoline or tetrahydroquinoline derivatives
US20020049223A1 (en) * 1999-11-05 2002-04-25 Elmore Steven W. Quinoline and naphthyridine carboxylic acid antibacterials
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
US7396841B2 (en) * 2000-08-18 2008-07-08 Takeda Pharmaceutical Company Limited Injections
EA006205B1 (ru) 2000-11-02 2005-10-27 Уайт 1-арил- или 1-алкилсульфонилгетероциклилбензазолы в качестве лигандов 5-гидрокситриптамина-6
ES2260458T3 (es) 2001-07-02 2006-11-01 Akzo Nobel N.V. Derivados de tetrahidroquinolina.
US7071210B2 (en) 2002-07-02 2006-07-04 Pfizer Inc. CETP inhibitors in combination with antihypertensive agents and uses thereof
DE10229777A1 (de) 2002-07-03 2004-01-29 Bayer Ag Indolin-Phenylsulfonamid-Derivate
US6894061B2 (en) 2002-12-04 2005-05-17 Wyeth Substituted dihydrophenanthridinesulfonamides
DE10300099A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Indol-Phenylsulfonamid-Derivate
US7276608B2 (en) * 2003-07-11 2007-10-02 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
EP1648455A4 (en) 2003-07-23 2009-03-04 Exelixis Inc MODULATORS OF ALK PROTEIN (ANAPLASTIC LYMPHOMA KINASE) AND METHODS OF USE
DE10335450A1 (de) * 2003-08-02 2005-02-17 Bayer Ag Indolin-Sulfanilsäureamide
GT200500183A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
PE20070404A1 (es) * 2005-07-29 2007-05-10 Wyeth Corp Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona
PE20070182A1 (es) * 2005-07-29 2007-03-06 Wyeth Corp Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona

Also Published As

Publication number Publication date
CL2008000675A1 (es) 2008-07-18
US20100234422A1 (en) 2010-09-16
WO2008109056A1 (en) 2008-09-12
PA8771801A1 (es) 2009-02-09
AR065521A1 (es) 2009-06-10
JP2010520283A (ja) 2010-06-10
EP2121657A1 (en) 2009-11-25
US7750038B2 (en) 2010-07-06
CA2679380A1 (en) 2008-09-12
US20080221160A1 (en) 2008-09-11
TW200848021A (en) 2008-12-16

Similar Documents

Publication Publication Date Title
MX2009009514A (es) Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona.
TW200731969A (en) Use of progesterone receptor modulators
TW200716621A (en) Polymorph form II of tanaproget
WO2008021338A3 (en) Tricyclic oxazolidone derivatives useful as pr modulators
ECSP055574A (es) Uso de derivados de tio-oxindol en el tratamiento de condiciones relacionadas con hormonas.
ECSP18047708A (es) Derivados de 17-hidroxi-17-pentafluoroetil-estra-4,9(10)-dien-11-arilo como antagonistas de progesterona y procedimientos para su preparación
WO2011098437A3 (de) Progesteronrezeptorantagonisten
WO2008021339A3 (en) Pyrrolidine and related derivatives useful as pr modulators
CU20120175A7 (es) Compuestos derivados de 6,7-dihidro-5h-benzo[7]anulenos
WO2009134725A3 (en) Monomethylamine progesteron antagonists such as cdb-4453 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer etc
MX2009009515A (es) Cianopirrol sulfonamidas utiles para la modulacion del receptor de progesterona.
DE602005019905D1 (de) -modulatoren
MX2009001698A (es) Derivados de oxazolidona como moduladores pr.
TN2017000482A1 (en) Selective progesterone receptor modulator (sprm) regimen.
MX2008000070A (es) Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona.
TW200726461A (en) Use of non-steroidal progesterone receptor modulators
CR9598A (es) Moduladores no esteroides de receptor de progesterona
SI1809602T1 (sl) Indolni derivati, uporabni kot modulatorji progesteronskega receptorja
EA201501000A1 (ru) Спироиндолиновые производные для применения в качестве антагонистов рецептора гонадотропин-рилизинг-гормона
UY30815A1 (es) Moduladores no esteroidales del receptor de progesterona

Legal Events

Date Code Title Description
HH Correction or change in general