PA8771801A1 - Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona - Google Patents

Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona

Info

Publication number
PA8771801A1
PA8771801A1 PA20088771801A PA8771801A PA8771801A1 PA 8771801 A1 PA8771801 A1 PA 8771801A1 PA 20088771801 A PA20088771801 A PA 20088771801A PA 8771801 A PA8771801 A PA 8771801A PA 8771801 A1 PA8771801 A1 PA 8771801A1
Authority
PA
Panama
Prior art keywords
heterocicles
sulphonylated
modulation
useful
compounds
Prior art date
Application number
PA20088771801A
Other languages
English (en)
Inventor
Fensome Andrew
Cameron Mccomas Casey
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8771801A1 publication Critical patent/PA8771801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE PROPORCIONAN COMPUESTOS DE LA SIGUIENTE ESTRUCTURA DONDE R1-R4 Y R6-R9 SE DEFINEN MAS ADELANTE, METODOS PARA PREPARAR Y USAR ESTOS COMPUESTOS PARA ANTICONCEPCION; PARA TRATAR O PREVENIR FIBROIDES, LEIOMIOMATA UTERINO, ENDOMETRIOSIS, HEMORRAGIA DISFUNCIONAL, SINDROME DEL OVARIO POLIQUISTICO,Y CARCINOMAS DEPENDIENTES DE HORMONA; PROPORCIONAR TERAPIA DE REEMPLAZO HORMONAL; ESTIMULAR LA INGESTA DE ALIMENTOS; DE SINCRONIZACION DEL ESTRO Y PARA TRATAR SINTOMAS RELACIONADOS CON EL CICLO.
PA20088771801A 2007-03-06 2008-03-06 Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona PA8771801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90519907P 2007-03-06 2007-03-06

Publications (1)

Publication Number Publication Date
PA8771801A1 true PA8771801A1 (es) 2009-02-09

Family

ID=39524346

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20088771801A PA8771801A1 (es) 2007-03-06 2008-03-06 Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona

Country Status (10)

Country Link
US (2) US7750038B2 (es)
EP (1) EP2121657A1 (es)
JP (1) JP2010520283A (es)
AR (1) AR065521A1 (es)
CA (1) CA2679380A1 (es)
CL (1) CL2008000675A1 (es)
MX (1) MX2009009514A (es)
PA (1) PA8771801A1 (es)
TW (1) TW200848021A (es)
WO (1) WO2008109056A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200848019A (en) * 2007-03-06 2008-12-16 Wyeth Corp Aryl sulfonamides useful for modulation of the progesterone receptor
US8038364B2 (en) 2007-08-07 2011-10-18 Saint-Gobain Technical Fabrics America, Inc. Reinforcement for asphaltic paving, method of paving, and process for making a grid with the coating for asphaltic paving
JP2009286773A (ja) * 2008-03-14 2009-12-10 Bayer Cropscience Ag 殺虫性縮環式アリール類
WO2014063056A1 (en) 2012-10-19 2014-04-24 Saint-Gobain Adfors Canada, Ltd. Composite tack film
PT3071203T (pt) 2013-11-18 2021-03-11 Forma Therapeutics Inc Composições de tetra-hidroquinolina como inibidores de bromodomínio bet
US9422281B2 (en) 2013-11-18 2016-08-23 Forma Therapeutics, Inc. Benzopiperazine compositions as BET bromodomain inhibitors

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW263508B (es) 1991-02-12 1995-11-21 Pfizer
DE19633751A1 (de) 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Arylpyridine
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
AU5570900A (en) 1999-07-01 2001-01-22 Sankyo Company Limited Indoline or tetrahydroquinoline derivatives
US20020049223A1 (en) 1999-11-05 2002-04-25 Elmore Steven W. Quinoline and naphthyridine carboxylic acid antibacterials
UA73119C2 (en) 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
US7396841B2 (en) 2000-08-18 2008-07-08 Takeda Pharmaceutical Company Limited Injections
HUP0303756A3 (en) 2000-11-02 2009-08-28 Wyeth Corp 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands and process for their preparation and pharmaceutical compositions containing them
PL367638A1 (en) 2001-07-02 2005-03-07 Akzo Nobel N.V. Tetrahydroquinoline derivatives
US7071210B2 (en) 2002-07-02 2006-07-04 Pfizer Inc. CETP inhibitors in combination with antihypertensive agents and uses thereof
DE10229777A1 (de) 2002-07-03 2004-01-29 Bayer Ag Indolin-Phenylsulfonamid-Derivate
US6894061B2 (en) 2002-12-04 2005-05-17 Wyeth Substituted dihydrophenanthridinesulfonamides
DE10300099A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Indol-Phenylsulfonamid-Derivate
WO2005007111A2 (en) 2003-07-11 2005-01-27 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
JP4836788B2 (ja) 2003-07-23 2011-12-14 エグゼリクシス， インコーポレイテッド 未分化リンパ腫キナーゼ変調因子及びその使用法
DE10335450A1 (de) 2003-08-02 2005-02-17 Bayer Ag Indolin-Sulfanilsäureamide
GT200500183A (es) 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
GT200500185A (es) 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
PE20070404A1 (es) 2005-07-29 2007-05-10 Wyeth Corp Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona
PE20070182A1 (es) 2005-07-29 2007-03-06 Wyeth Corp Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona

Also Published As

Publication number Publication date
CA2679380A1 (en) 2008-09-12
US7750038B2 (en) 2010-07-06
EP2121657A1 (en) 2009-11-25
US20080221160A1 (en) 2008-09-11
CL2008000675A1 (es) 2008-07-18
AR065521A1 (es) 2009-06-10
US20100234422A1 (en) 2010-09-16
MX2009009514A (es) 2009-09-16
WO2008109056A1 (en) 2008-09-12
JP2010520283A (ja) 2010-06-10
TW200848021A (en) 2008-12-16

Similar Documents

Publication Publication Date Title
PA8771801A1 (es) Heterociclos sulfonilados utiles para la modulacion del receptor de progesterona
CU20120175A7 (es) Compuestos derivados de 6,7-dihidro-5h-benzo[7]anulenos
AR054586A1 (es) Uso de moduladores del receptor de progesterona
ME01122B (me) Jedinjenja i postupci za liječenje raka dojke
HN2012000137A (es) Derivados de 17 - hidroxi - 17 - pentafluoroetil - estra - 4, 9(10) - dien - 11 - arilo, procedimientos para su preparacion y su uso para el tratamiento de enfermedades
PE20171134A1 (es) Anticuerpos neutralizadores contra el receptor de prolactina
EA200970835A1 (ru) Индазолы, применяемые для лечения расстройств, опосредуемых эстрогеновым рецептором бета
PE20130815A1 (es) Una composicion de combinacion farmaceutica y metodos para tratar la diabetes y los trastornos metabolicos
MX2015016825A (es) Compuestos de pirazol como moduladores del receptor de hormona estimuladora de foliculos y sus usos.
CR10826A (es) Composiciones y metodos para suprimir la proliferacion endometrial
BR112016002572A2 (pt) peptídeos
EA201990106A1 (ru) Режим приема селективного модулятора рецептора прогестерона (sprm)
ECSP078043A (es) Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona
SV2009003168A (es) Derivados de oxazolidona como moduladores pr
TW200726461A (en) Use of non-steroidal progesterone receptor modulators
MX2009009515A (es) Cianopirrol sulfonamidas utiles para la modulacion del receptor de progesterona.
GT200600271A (es) Moduladores no esterides de receptores de progesterona
AR095834A1 (es) Forma de dosificación de un antagonista del receptor de progesterona, composición farmacéutica
PA8771701A1 (es) Síntesis y caracterización de la forma ii polimórfica de 4-(4,-dimetil-2oxooxazolidin--il)tiazol-4il)benzonitrilo"
UY30815A1 (es) Moduladores no esteroidales del receptor de progesterona
TH85420B (th) การใช้สารปรับโพรเจสเตอโรนรีเซปเตอร์ชนิดนอน-สเตียรอยด์