NO20080440L - Ikke-steroide progesteronreseptormodulatorer - Google Patents

Ikke-steroide progesteronreseptormodulatorer

Info

Publication number
NO20080440L
NO20080440L NO20080440A NO20080440A NO20080440L NO 20080440 L NO20080440 L NO 20080440L NO 20080440 A NO20080440 A NO 20080440A NO 20080440 A NO20080440 A NO 20080440A NO 20080440 L NO20080440 L NO 20080440L
Authority
NO
Norway
Prior art keywords
receptor modulators
progesterone receptor
therapy
prophylaxis
compounds
Prior art date
Application number
NO20080440A
Other languages
English (en)
Inventor
Ulrike Fuhrmann
Wolfgang Schwede
Lothar Sobek
Peter Droescher
Alexander Hillisch
Norbert Schmees
Ulrich Bothe
Guenter Kaufmann
Carsten Moeller
Anja Schmidt
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of NO20080440L publication Critical patent/NO20080440L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Foreliggende oppfinnelse vedrører ikke-steroide progesteronreseptormodulatorer med generell formel (I), en fremgangsmåte for deres fremstilling, anvendelsen av progesteronreseptormodulatorene for fremstilling av medikamenter og farmasøytiske preparater som omfatter disse forbindelsene. Forbindelsene ifølge oppfinnelsen er passende for terapien og profylaksen av gynekologiske forstyrrelser slik som endometriose, leiomyomer i livmoren, feilaktig blødning og dysmenoré og til terapien og profylaksen av hormonavhengige tumorer og til anvendelse for kvinnelig fertilitetskontroll og til hormonerstatningsterapi.
NO20080440A 2005-06-24 2008-01-23 Ikke-steroide progesteronreseptormodulatorer NO20080440L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005030292A DE102005030292A1 (de) 2005-06-24 2005-06-24 Nichtsteroidale Progesteronrezeptor-Modulatoren
PCT/EP2006/006531 WO2006136461A2 (en) 2005-06-24 2006-06-22 Non-steroidal progesterone receptor modulators

Publications (1)

Publication Number Publication Date
NO20080440L true NO20080440L (no) 2008-03-25

Family

ID=37199176

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080440A NO20080440L (no) 2005-06-24 2008-01-23 Ikke-steroide progesteronreseptormodulatorer

Country Status (22)

Country Link
EP (1) EP1902049A2 (no)
JP (1) JP2008543910A (no)
KR (1) KR20080030622A (no)
CN (1) CN101248066A (no)
AR (1) AR054519A1 (no)
AU (1) AU2006261048A1 (no)
BR (1) BRPI0611903A2 (no)
CA (1) CA2611897A1 (no)
CR (1) CR9598A (no)
DE (1) DE102005030292A1 (no)
DO (1) DOP2006000148A (no)
EA (1) EA200702524A1 (no)
EC (1) ECSP078044A (no)
GT (1) GT200600271A (no)
IL (1) IL188021A0 (no)
MX (1) MX2008000072A (no)
NO (1) NO20080440L (no)
PE (1) PE20070125A1 (no)
TW (1) TW200740778A (no)
UY (1) UY29624A1 (no)
WO (1) WO2006136461A2 (no)
ZA (1) ZA200800690B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30805A1 (es) * 2006-12-21 2008-07-31 Bayer Schering Pharma Ag Moduladores no esteroides de receptores de progesterona
DE102007032800A1 (de) * 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007058747A1 (de) * 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
WO2010002075A1 (en) * 2008-07-02 2010-01-07 Pharmacostech Co., Ltd. Methods for preparing amide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19856475A1 (de) * 1998-11-27 2000-05-31 Schering Ag Nichtsteroidale Entzündungshemmer
EP1344776A1 (en) * 2002-03-11 2003-09-17 Schering Aktiengesellschaft 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders
BRPI0412231A (pt) * 2003-07-01 2006-08-22 Schering Ag derivados de pentanol substituìdos heterociclicamente, processos para a sua preparação e sua aplicação como inibidores de inflamação

Also Published As

Publication number Publication date
BRPI0611903A2 (pt) 2010-10-05
CA2611897A1 (en) 2006-12-28
PE20070125A1 (es) 2007-02-14
KR20080030622A (ko) 2008-04-04
CR9598A (es) 2008-04-09
UY29624A1 (es) 2007-01-31
TW200740778A (en) 2007-11-01
JP2008543910A (ja) 2008-12-04
MX2008000072A (es) 2008-03-24
AR054519A1 (es) 2007-06-27
WO2006136461A2 (en) 2006-12-28
WO2006136461A3 (en) 2007-03-15
DE102005030292A1 (de) 2007-01-11
IL188021A0 (en) 2008-03-20
ZA200800690B (en) 2009-09-30
EA200702524A1 (ru) 2008-06-30
ECSP078044A (es) 2008-01-23
EP1902049A2 (en) 2008-03-26
CN101248066A (zh) 2008-08-20
DOP2006000148A (es) 2007-07-15
GT200600271A (es) 2007-02-05
AU2006261048A1 (en) 2006-12-28

Similar Documents

Publication Publication Date Title
NO20090628L (no) Pyridizinon derivativater
NO20082124L (no) Bifenyloksyeddiksyrederivater for behandling av respiratorisk sykdom
TW200637874A (en) Peptides with neuropeptide-2 receptor (Y2R) agonist activity
BRPI0506721A (pt) composto ou um sal de adição de ácido do mesmo
TW200806311A (en) Neuropeptide-2 receptor-agonists
NO20055852L (no) Nye peptider som binder til erytropoietinreseptoren
EA200970835A1 (ru) Индазолы, применяемые для лечения расстройств, опосредуемых эстрогеновым рецептором бета
NO20080441L (no) Benzofuranonderivater som ikke-steroide progesteronreseptormodulatorer
NO20090979L (no) (3-amino-1,2,3,4-tetrahydro-9H-karbazol-9-yl)-eddiksyrederivater
NO20062679L (no) Nye 17 β -hydroksysteroid-dehydrogenase-type 1-inhibitorer
EA200970065A1 (ru) Производные пиперазинила, предназначенные для лечения заболеваний, опосредованных рецептором gpr38
BRPI0511466A (pt) agonistas peptìdicos do receptor de vasopressina
TW200640863A (en) Compounds which potentiate glutamate receptor and uses thereof in medicine
NO20045217L (no) Anvendelse av tio-oxindolderivater for behandling av hormon relaterte tilstander
EA200800421A1 (ru) Соединения
WO2007113202A8 (en) Piperazine derivatives as growth hormone secretagogue (ghs) receptor agonists
NO20080440L (no) Ikke-steroide progesteronreseptormodulatorer
AU2003255355A1 (en) Progesterone receptor modulators having an increased antigonadotropic activity for use in female fertility testing and hormone replacement therapy
NO20090457L (no) Oksazolidon derivativer som PR modulatorer
DOP2006000147A (es) Uso de modulares no esteroides de receptores de progesterona.
UA92500C2 (ru) Цианопирролсульфонамидные модуляторы прогестеронового рецептора и их применение
DK2200980T3 (da) Aminoarylsulfonamidforbindelser og deres anvendelse som 5-HT6-ligander
WO2009071691A3 (de) Oxindol-derivate und ihre verwendung als medikament
WO2008113851A3 (en) Novel c11 modified retrosteroids as progesterone receptor modulator compounds
NO20061290L (no) Nye forbindelser

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application