ECSP078044A - Moduladores no esteroides de receptor de progesterona - Google Patents
Moduladores no esteroides de receptor de progesteronaInfo
- Publication number
- ECSP078044A ECSP078044A EC2007008044A ECSP078044A ECSP078044A EC SP078044 A ECSP078044 A EC SP078044A EC 2007008044 A EC2007008044 A EC 2007008044A EC SP078044 A ECSP078044 A EC SP078044A EC SP078044 A ECSP078044 A EC SP078044A
- Authority
- EC
- Ecuador
- Prior art keywords
- therapy
- prevention
- receptor modulators
- progesterone receptor
- steroid progesterone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a moduladores no-esteroides de receptor de progesterona de la fórmula general (I), al proceso para su preparación, al uso de los moduladores del receptor de progesterona para la producción de medicamentos así como también composiciones farmacéuticas que contienen estos compuestos. Los compuestos según la invención son apropiados para la terapia y la prevención de enfermedades ginecológicas tales como endometriosis, leiomiomas de útero, hemorragias disfuncionales y dismenorrea y para la terapia y la prevención de tumores dependientes de hormonas y para el uso para el control de la fertilidad femenina y para la terapia de reemplazo hormonal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005030292A DE102005030292A1 (de) | 2005-06-24 | 2005-06-24 | Nichtsteroidale Progesteronrezeptor-Modulatoren |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP078044A true ECSP078044A (es) | 2008-01-23 |
Family
ID=37199176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2007008044A ECSP078044A (es) | 2005-06-24 | 2007-12-21 | Moduladores no esteroides de receptor de progesterona |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1902049A2 (es) |
JP (1) | JP2008543910A (es) |
KR (1) | KR20080030622A (es) |
CN (1) | CN101248066A (es) |
AR (1) | AR054519A1 (es) |
AU (1) | AU2006261048A1 (es) |
BR (1) | BRPI0611903A2 (es) |
CA (1) | CA2611897A1 (es) |
CR (1) | CR9598A (es) |
DE (1) | DE102005030292A1 (es) |
DO (1) | DOP2006000148A (es) |
EA (1) | EA200702524A1 (es) |
EC (1) | ECSP078044A (es) |
GT (1) | GT200600271A (es) |
IL (1) | IL188021A0 (es) |
MX (1) | MX2008000072A (es) |
NO (1) | NO20080440L (es) |
PE (1) | PE20070125A1 (es) |
TW (1) | TW200740778A (es) |
UY (1) | UY29624A1 (es) |
WO (1) | WO2006136461A2 (es) |
ZA (1) | ZA200800690B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY30805A1 (es) * | 2006-12-21 | 2008-07-31 | Bayer Schering Pharma Ag | Moduladores no esteroides de receptores de progesterona |
DE102007032800A1 (de) * | 2007-07-10 | 2009-01-15 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
DE102007058747A1 (de) | 2007-12-05 | 2009-06-10 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
WO2010002075A1 (en) * | 2008-07-02 | 2010-01-07 | Pharmacostech Co., Ltd. | Methods for preparing amide derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19856475A1 (de) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nichtsteroidale Entzündungshemmer |
EP1344776A1 (en) * | 2002-03-11 | 2003-09-17 | Schering Aktiengesellschaft | 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders |
BRPI0412231A (pt) * | 2003-07-01 | 2006-08-22 | Schering Ag | derivados de pentanol substituìdos heterociclicamente, processos para a sua preparação e sua aplicação como inibidores de inflamação |
-
2005
- 2005-06-24 DE DE102005030292A patent/DE102005030292A1/de not_active Ceased
-
2006
- 2006-06-22 CN CNA2006800308707A patent/CN101248066A/zh active Pending
- 2006-06-22 BR BRPI0611903-4A patent/BRPI0611903A2/pt not_active Application Discontinuation
- 2006-06-22 JP JP2008517444A patent/JP2008543910A/ja active Pending
- 2006-06-22 MX MX2008000072A patent/MX2008000072A/es not_active Application Discontinuation
- 2006-06-22 EP EP06762404A patent/EP1902049A2/en not_active Withdrawn
- 2006-06-22 EA EA200702524A patent/EA200702524A1/ru unknown
- 2006-06-22 KR KR1020087001793A patent/KR20080030622A/ko not_active Application Discontinuation
- 2006-06-22 WO PCT/EP2006/006531 patent/WO2006136461A2/en active Application Filing
- 2006-06-22 CA CA002611897A patent/CA2611897A1/en not_active Abandoned
- 2006-06-22 AU AU2006261048A patent/AU2006261048A1/en not_active Abandoned
- 2006-06-23 TW TW095122742A patent/TW200740778A/zh unknown
- 2006-06-26 DO DO2006000148A patent/DOP2006000148A/es unknown
- 2006-06-26 UY UY29624A patent/UY29624A1/es not_active Application Discontinuation
- 2006-06-26 PE PE2006000733A patent/PE20070125A1/es not_active Application Discontinuation
- 2006-06-27 AR ARP060102750A patent/AR054519A1/es unknown
- 2006-06-28 GT GT200600271A patent/GT200600271A/es unknown
-
2007
- 2007-12-10 IL IL188021A patent/IL188021A0/en unknown
- 2007-12-17 CR CR9598A patent/CR9598A/es not_active Application Discontinuation
- 2007-12-21 EC EC2007008044A patent/ECSP078044A/es unknown
-
2008
- 2008-01-23 ZA ZA200800690A patent/ZA200800690B/xx unknown
- 2008-01-23 NO NO20080440A patent/NO20080440L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20080440L (no) | 2008-03-25 |
JP2008543910A (ja) | 2008-12-04 |
MX2008000072A (es) | 2008-03-24 |
TW200740778A (en) | 2007-11-01 |
UY29624A1 (es) | 2007-01-31 |
GT200600271A (es) | 2007-02-05 |
PE20070125A1 (es) | 2007-02-14 |
EP1902049A2 (en) | 2008-03-26 |
DOP2006000148A (es) | 2007-07-15 |
EA200702524A1 (ru) | 2008-06-30 |
KR20080030622A (ko) | 2008-04-04 |
CA2611897A1 (en) | 2006-12-28 |
DE102005030292A1 (de) | 2007-01-11 |
ZA200800690B (en) | 2009-09-30 |
BRPI0611903A2 (pt) | 2010-10-05 |
AU2006261048A1 (en) | 2006-12-28 |
WO2006136461A2 (en) | 2006-12-28 |
WO2006136461A3 (en) | 2007-03-15 |
CN101248066A (zh) | 2008-08-20 |
IL188021A0 (en) | 2008-03-20 |
AR054519A1 (es) | 2007-06-27 |
CR9598A (es) | 2008-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR054586A1 (es) | Uso de moduladores del receptor de progesterona | |
CU20120175A7 (es) | Compuestos derivados de 6,7-dihidro-5h-benzo[7]anulenos | |
DOP2009000148A (es) | Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides | |
ECSP18047708A (es) | Derivados de 17-hidroxi-17-pentafluoroetil-estra-4,9(10)-dien-11-arilo como antagonistas de progesterona y procedimientos para su preparación | |
ECSP078043A (es) | Derivados de benzofurarona como moduladores no esteroides de receptores de progesterona | |
SV2010003580A (es) | Agonistas novedosos de los receptores de glucocorticoides | |
EA201491096A1 (ru) | Производные 6,7-дигидро-5h-бензо[7]аннулена, способ их получения, фармацевтические препараты, которые их содержат, а также их применение для изготовления лекарственных средств | |
UY29625A1 (es) | Uso de moduladores no esteroides de receptores de progesterona | |
ECSP078044A (es) | Moduladores no esteroides de receptor de progesterona | |
CR9627A (es) | Cyanopyrrole-sulfonamide progesterone receptor modulators and uses thereof | |
UY30805A1 (es) | Moduladores no esteroides de receptores de progesterona | |
UY30815A1 (es) | Moduladores no esteroidales del receptor de progesterona | |
WO2008113851A3 (en) | Novel c11 modified retrosteroids as progesterone receptor modulator compounds | |
CU20090109A7 (es) | Derivados de éster y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides | |
TH85615A (th) | สารปรับโพรเจสเตอโรนรีเซปเตอร์ชนิดนอนสเตียรอยด์ |