NO20043610L - Fenylpyrimidinaminer som IgE inhibitorer - Google Patents

Fenylpyrimidinaminer som IgE inhibitorer

Info

Publication number
NO20043610L
NO20043610L NO20043610A NO20043610A NO20043610L NO 20043610 L NO20043610 L NO 20043610L NO 20043610 A NO20043610 A NO 20043610A NO 20043610 A NO20043610 A NO 20043610A NO 20043610 L NO20043610 L NO 20043610L
Authority
NO
Norway
Prior art keywords
phenylpyrimidinamines
ige inhibitors
ige
inhibitors
Prior art date
Application number
NO20043610A
Other languages
English (en)
Norwegian (no)
Inventor
Peter Ettmayer
Murty Bulusu
Klaus Weigand
Max Woisetschlager
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0202381A external-priority patent/GB0202381D0/en
Priority claimed from GB0221953A external-priority patent/GB0221953D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20043610L publication Critical patent/NO20043610L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20043610A 2002-02-01 2004-08-30 Fenylpyrimidinaminer som IgE inhibitorer NO20043610L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0202381A GB0202381D0 (en) 2002-02-01 2002-02-01 Organic compounds
GB0221953A GB0221953D0 (en) 2002-09-20 2002-09-20 Organic compounds
PCT/EP2003/000973 WO2003063871A1 (en) 2002-02-01 2003-01-31 Phenylpyrimidine amines as ige inhibitors

Publications (1)

Publication Number Publication Date
NO20043610L true NO20043610L (no) 2004-10-05

Family

ID=27665364

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043610A NO20043610L (no) 2002-02-01 2004-08-30 Fenylpyrimidinaminer som IgE inhibitorer

Country Status (23)

Country Link
US (2) US20050119255A1 (de)
EP (1) EP1474146B1 (de)
JP (1) JP4393198B2 (de)
KR (1) KR20040081159A (de)
CN (2) CN101684097A (de)
AR (1) AR038368A1 (de)
AT (1) ATE406165T1 (de)
AU (1) AU2003206810B2 (de)
BR (1) BR0307379A (de)
CA (1) CA2471883C (de)
DE (1) DE60323205D1 (de)
EC (1) ECSP045213A (de)
ES (1) ES2312749T3 (de)
IL (1) IL162766A0 (de)
MX (1) MXPA04007395A (de)
NO (1) NO20043610L (de)
NZ (1) NZ534229A (de)
PE (1) PE20030983A1 (de)
PL (1) PL370666A1 (de)
PT (1) PT1474146E (de)
RU (1) RU2004126614A (de)
TW (1) TW200302728A (de)
WO (1) WO2003063871A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050014753A1 (en) * 2003-04-04 2005-01-20 Irm Llc Novel compounds and compositions as protein kinase inhibitors
CA2533474A1 (en) * 2003-07-30 2005-02-10 Shudong Wang 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
JPWO2005040135A1 (ja) * 2003-10-24 2007-03-08 小野薬品工業株式会社 抗ストレス薬およびその医薬用途
EP1933839A1 (de) 2005-09-29 2008-06-25 Novartis AG Phenyl-(4-phenyl-pyrimidin-2-yl)-amine für erhöhte immuntoleranz
EP2195328A4 (de) * 2007-08-15 2011-06-15 Cytokinetics Inc Bestimmte chemische einheiten, zusammensetzungen und verfahren
CA3162388A1 (en) 2019-12-20 2021-06-24 Alfredo C. Castro 4-phenyl-n-(phenyl)thiazol-2-amine derivatives and related compounds as aryl hydrocarbon receptor (ahr) agonists for the treatment of e.g. angiogenesis implicated or inflammatory disorder

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185039A (en) 1966-03-31 1970-03-18 Ici Ltd Pyrimidine Derivatives and Compositions containing them
GB2001069B (en) 1977-07-12 1982-01-20 Scras Pyrimidine derivatives
AU5319479A (en) 1978-12-22 1980-06-26 Ici Australia Limited Pyrimidinyl amino phenoxy carboxylate derivatives
US4351939A (en) 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
DE3270906D1 (en) 1982-01-14 1986-06-05 Merck Patent Gmbh Liquid crystal mixtures
FR2536071B1 (fr) 1982-11-12 1986-07-11 Sanofi Sa Sels acides de 2-piperazinopyrimidine, procede pour leur preparation et compositions pharmaceutiques en contenant
FR2547821B1 (fr) 1983-06-24 1985-12-06 Sanofi Sa Sel de 2-piperazinopyrimidine, procede pour sa preparation et compositions pharmaceutiques en contenant
US4659363A (en) 1983-07-25 1987-04-21 Ciba-Geigy Corporation N-(2-nitrophenyl)-2-aminopyrimidine derivatives, the preparation and use thereof
EP0164204A1 (de) 1984-05-12 1985-12-11 FISONS plc Pharmazeutisch nützliche Pyrimidine
ATE60591T1 (de) 1984-06-25 1991-02-15 Ciba Geigy Ag Pyrimidinderivate wirksam als schaedlingsbekaempfungsmittel.
ATE135699T1 (de) 1986-01-13 1996-04-15 American Cyanamid Co 4,5,6-substituierte 2-pyrimidinamine
DE3614060A1 (de) 1986-04-23 1987-10-29 Schering Ag Pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
EP0254259A3 (de) 1986-07-21 1989-11-23 Otsuka Pharmaceutical Factory, Inc. p-Aminophenol-Derivate
DE3788494D1 (de) 1986-10-13 1994-01-27 Ciba Geigy Harnstoffe.
US4826990A (en) 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
US4973690A (en) 1988-04-12 1990-11-27 Ciba-Geigy Corporation Novel ureas
ATE92051T1 (de) 1988-04-12 1993-08-15 Ciba Geigy Ag Harnstoffe.
JPH02308248A (ja) 1989-05-24 1990-12-21 Fuji Photo Film Co Ltd アミノピリミジン系色素形成カプラーおよび該カプラーを含有するハロゲン化銀カラー写真感光材料
US5521184A (en) 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
US5516775A (en) 1992-08-31 1996-05-14 Ciba-Geigy Corporation Further use of pyrimidine derivatives
AU693475B2 (en) 1993-10-01 1998-07-02 Novartis Ag Pyrimidineamine derivatives and processes for the preparation thereof
ATE208772T1 (de) 1993-10-01 2001-11-15 Novartis Erfind Verwalt Gmbh Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
AU693114B2 (en) 1993-10-01 1998-06-25 Novartis Ag Pharmacologically active pyrimidineamine derivatives and processes for the preparation thereof
CZ101496A3 (en) * 1993-10-12 1996-11-13 Du Pont Merck Pharma N-alkyl-n-aryl-pyrimidinamines and derivatives thereof
US5750531A (en) 1994-08-13 1998-05-12 Yuhan Corporation Pyrimidine derivatives and processes for the preparation thereof
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
AR038955A1 (es) 1996-12-05 2005-02-02 Amgen Inc Compuestos de pirimidinona y piridona sustituidos y metodos para su uso
ES2203937T3 (es) * 1997-03-26 2004-04-16 Taisho Pharmaceutical Co., Ltd Derivados de 4-tetrahidropiridilpirimidina.
IN188411B (de) 1997-03-27 2002-09-21 Yuhan Corp
US6440965B1 (en) 1997-10-15 2002-08-27 Krenitsky Pharmaceuticals, Inc. Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system
WO1999035140A1 (en) * 1998-01-12 1999-07-15 Novartis Ag PYRIDINYLPYRIMIDINE AMINES AS IMMUNOGLOBULINE E (IgE) SYNTHESIS INHIBITORS
CN1231440C (zh) * 1998-01-28 2005-12-14 盐野义制药株式会社 新的三环化合物
AU751573C (en) 1998-03-27 2003-10-09 Janssen Pharmaceutica N.V. HIV inhibiting pyrimidine derivatives
TWI241298B (en) 1998-09-25 2005-10-11 Mitsubishi Chem Corp Pyrimidone derivatives
HUP0104171A3 (en) * 1998-11-17 2002-04-29 Ihara Chemical Ind Co Pyrimidinylbenzimidazole and triatinylbenzimidazole derivatives, intermediates and use as agricultura/horticultural fungicides
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
ATE365158T1 (de) 1999-04-28 2007-07-15 Inst Med Molecular Design Inc Pyrimidincarbonsäurederivate
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
GB0003224D0 (en) 2000-02-11 2000-04-05 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
BR0307379A (pt) 2004-12-28
CA2471883C (en) 2010-12-07
CA2471883A1 (en) 2003-08-07
WO2003063871A1 (en) 2003-08-07
EP1474146A1 (de) 2004-11-10
ECSP045213A (es) 2004-09-28
EP1474146B1 (de) 2008-08-27
US20070281956A1 (en) 2007-12-06
JP2005516051A (ja) 2005-06-02
AU2003206810B2 (en) 2006-06-29
IL162766A0 (en) 2005-11-20
TW200302728A (en) 2003-08-16
CN101684097A (zh) 2010-03-31
PE20030983A1 (es) 2004-01-26
KR20040081159A (ko) 2004-09-20
RU2004126614A (ru) 2005-05-27
ATE406165T1 (de) 2008-09-15
CN1622807A (zh) 2005-06-01
NZ534229A (en) 2005-04-29
JP4393198B2 (ja) 2010-01-06
DE60323205D1 (en) 2008-10-09
PT1474146E (pt) 2008-12-05
US20050119255A1 (en) 2005-06-02
ES2312749T3 (es) 2009-03-01
AR038368A1 (es) 2005-01-12
PL370666A1 (en) 2005-05-30
US7759357B2 (en) 2010-07-20
MXPA04007395A (es) 2005-06-17

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application