NO20033561L - 4-Aminobenzopyranderivater - Google Patents

4-Aminobenzopyranderivater

Info

Publication number
NO20033561L
NO20033561L NO20033561A NO20033561A NO20033561L NO 20033561 L NO20033561 L NO 20033561L NO 20033561 A NO20033561 A NO 20033561A NO 20033561 A NO20033561 A NO 20033561A NO 20033561 L NO20033561 L NO 20033561L
Authority
NO
Norway
Prior art keywords
group
hydrogen atom
nitro
rog
aminobenzopyranderivater
Prior art date
Application number
NO20033561A
Other languages
English (en)
Other versions
NO20033561D0 (no
NO328708B1 (no
Inventor
Yoshio Ohara
Kazuhiko Ohrai
Kazufumi Yanagihara
Yukihiro Shigeta
Toru Tsukagoshi
Toru Yamashita
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of NO20033561D0 publication Critical patent/NO20033561D0/no
Publication of NO20033561L publication Critical patent/NO20033561L/no
Publication of NO328708B1 publication Critical patent/NO328708B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Insulating Materials (AREA)
  • Discharging, Photosensitive Material Shape In Electrophotography (AREA)
  • External Artificial Organs (AREA)
  • Non-Adjustable Resistors (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Foreliggende oppfinnelse vedrører benzopyranderivater med formelen (I). hvori Rog Rhver representerer uavhengig en C-alkyl- gruppe, osv., Rrepresenterer en hydroksylgruppe, osv, Rrepresenterer et hydrogenatom, osv , Rrepresenterer et hydrogenatom, Rrepresenterer et hydrogenatom, osv., X er fraværende eller representerer X=0, osv, Rrepresenterer et hydrogenatom, en Calkylgruppe, osv., Rrepresenterer et hydrogenatom eller en nitrogruppe, når Rrepresenterer en nitrogruppe representerer Y en C.alkylengruppe, - (CH)m-CR11H)n- eller -(CH)-0-(CH)p-, Rrepresenterer et hydrogenatom, en aminogruppe, en C-alkoksygruppe, en C-alkyltiogruppe, en C,-, alkylaminogruppe, en C.al- koksykarbonylaminogruppe, osv , eller farmasøytiske akseptable salter derav. Disse forbindelser er nyttige som et antiarytmisk middel.
NO20033561A 2001-02-14 2003-08-12 4-Aminobenzopyranderivater NO328708B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001036293 2001-02-14
PCT/JP2002/001236 WO2002064581A1 (en) 2001-02-14 2002-02-14 4-aminobenzopyran derivatives

Publications (3)

Publication Number Publication Date
NO20033561D0 NO20033561D0 (no) 2003-08-12
NO20033561L true NO20033561L (no) 2003-10-14
NO328708B1 NO328708B1 (no) 2010-05-03

Family

ID=18899587

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033561A NO328708B1 (no) 2001-02-14 2003-08-12 4-Aminobenzopyranderivater

Country Status (19)

Country Link
US (1) US6809114B2 (no)
EP (1) EP1360182B1 (no)
JP (1) JP2002316981A (no)
KR (1) KR100849351B1 (no)
CN (1) CN1250536C (no)
AT (1) ATE273294T1 (no)
AU (1) AU2002232182B2 (no)
CA (1) CA2436438C (no)
CZ (1) CZ20032145A3 (no)
DE (1) DE60200937T2 (no)
HU (1) HUP0303186A3 (no)
IL (2) IL156943A0 (no)
NO (1) NO328708B1 (no)
NZ (1) NZ527040A (no)
RU (1) RU2288226C2 (no)
SK (1) SK287023B6 (no)
TW (1) TW589305B (no)
UA (1) UA74052C2 (no)
WO (1) WO2002064581A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315950D0 (en) 2003-06-11 2003-08-13 Xention Discovery Ltd Compounds
TWI346112B (en) 2004-02-25 2011-08-01 Nissan Chemical Ind Ltd Benzopyran compound
AU2005223612B2 (en) 2004-03-23 2010-06-24 Nissan Chemical Industries, Ltd. Tricyclic benzopyran compound as anti-arrhythmic agents
GB0412986D0 (en) 2004-06-10 2004-07-14 Xention Discovery Ltd Compounds
US7576212B2 (en) 2004-12-09 2009-08-18 Xention Limited Thieno[2,3-B] pyridines as potassium channel inhibitors
GB0525164D0 (en) 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
TW201022223A (en) * 2008-08-14 2010-06-16 Nissan Chemical Ind Ltd Di-substituted benzopyrane compound
GB0815781D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815782D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB201105659D0 (en) 2011-04-01 2011-05-18 Xention Ltd Compounds
NO3175985T3 (no) 2011-07-01 2018-04-28
AR090037A1 (es) 2011-11-15 2014-10-15 Xention Ltd Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
WO2013072693A1 (en) 2011-11-15 2013-05-23 Xention Limited Thieno [2, 3 - c] pyrazoles for use as potassium channel inhibitors
US20150045305A1 (en) 2012-01-27 2015-02-12 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9005318D0 (en) * 1990-03-09 1990-05-02 Isis Innovation Antiarrhythmic agents
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
CZ2002802A3 (cs) * 1999-09-17 2003-02-12 Nissan Chemical Industries, Ltd. Benzopyranové deriváty
US6555574B1 (en) * 1999-09-24 2003-04-29 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
US6677371B1 (en) * 1999-10-05 2004-01-13 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative

Also Published As

Publication number Publication date
ATE273294T1 (de) 2004-08-15
WO2002064581A1 (en) 2002-08-22
RU2288226C2 (ru) 2006-11-27
DE60200937T2 (de) 2005-07-28
KR100849351B1 (ko) 2008-07-29
CN1529702A (zh) 2004-09-15
SK287023B6 (sk) 2009-09-07
US20040068002A1 (en) 2004-04-08
TW589305B (en) 2004-06-01
IL156943A (en) 2007-05-15
AU2002232182B2 (en) 2006-09-21
NO20033561D0 (no) 2003-08-12
CA2436438C (en) 2009-04-07
IL156943A0 (en) 2004-02-08
CA2436438A1 (en) 2002-08-22
HUP0303186A3 (en) 2007-06-28
UA74052C2 (en) 2005-10-17
NZ527040A (en) 2004-04-30
KR20040018334A (ko) 2004-03-03
DE60200937D1 (de) 2004-09-16
EP1360182A1 (en) 2003-11-12
EP1360182B1 (en) 2004-08-11
RU2003127748A (ru) 2005-03-20
NO328708B1 (no) 2010-05-03
CN1250536C (zh) 2006-04-12
US6809114B2 (en) 2004-10-26
HUP0303186A2 (hu) 2003-12-29
SK10002003A3 (sk) 2004-04-06
JP2002316981A (ja) 2002-10-31
CZ20032145A3 (cs) 2003-12-17

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