KR900000351A - 1-아릴-나프토일아민 및 그의 제조방법 - Google Patents

1-아릴-나프토일아민 및 그의 제조방법 Download PDF

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KR900000351A
KR900000351A KR1019890008415A KR890008415A KR900000351A KR 900000351 A KR900000351 A KR 900000351A KR 1019890008415 A KR1019890008415 A KR 1019890008415A KR 890008415 A KR890008415 A KR 890008415A KR 900000351 A KR900000351 A KR 900000351A
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리블리 피테르
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베르너 발데크
시바-가이기 아게
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    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • A01N43/30—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3 with two oxygen atoms in positions 1,3, condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/32—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms six-membered rings
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/66—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems and singly-bound oxygen atoms, bound to the same carbon skeleton
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic

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Abstract

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Description

1-아릴-나프토일아민 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (18)

  1. 하기 일반식(Ⅰ)의 1-아릴-2-나프토일아민 및 그의 부가염 :
    상기식에서, R1은 할로겐, 니트로, 시아노, 할로겐 및/또는 C1-C3알콕시에 의해 비치환, 1치환 또는 다중 치환된 C1-C6알킬, C3-C6시클로알킬, OR4, NR5, R6, CO2R5, CONR5R6또는 NHCOR7이고, 여기서 핵의 2인접 위치는 불소에 의해 비치환 1치환 또는 다중 치환된 메틸렌디옥시 또는 디에틸렌디옥시기에 의해 가교되고, R4는 수소, 또는 C1-C3알콕시에 의해 치환 또는 비치환되거나 할로겐에 의해 1치환 또는 다중치환된 C1-C6알킬, C3-C4알켄일, 2-프로핀일, 3-할로-2-프로핀일, |또는 COR7이고, R5및 R6각각은 서로 독립적으로 H 또는 C1-C4알킬이고, R7은 C1-C4알킬이고, Z는 산소 또는 NH이고, a 및 b는 각 6-원 고리에서 점령된 위치의 수를 나타내고, a는 1 내지 3이고, b는 0내지 3이고, a와b의 합이 1 이상일때,R1은 같거나 서로 다르며, X는 산소, 황 또는 NH이고, R2및 R3각각은 서로 독립적으로 C1-C4알콕시, 할로겐 또는 시아노에의해 치환 또는 비치환된 C1-C6알킬, C3-C7시클로알킬, C3-C7알켄일 또는 라디칼
    (여기서 n은 0 또는 1임)이거나, 또는 R2및 R3는 함께 C1-C4알킬에 의해 비치환, 1치환 또는 2치환된 헤테로 싸이클을 질소원자와 함께 형성할 수 있는 C4-C7알킬렌이고, 이 사슬에서 메틸렌기중 하나는 O, S 또는 NR7에 의해 치환될 수 있고, R2는 수소일 수 있다.
  2. 제1항에 있어서, R1이 할로겐, 니트로, C1-C6알킬, C3-C6시클로알킬, 메틸렌디옥시, 모노플루오로메틸렌디옥시, 디플루오로메틸렌디옥시, 비피환 에틸렌디옥시, 불소에 의해 1치환 또는 다중 치환된 에틸렌디옥시, OR4또는 NR5R6이고 ; R4는 수소, 또는 C1-C3알콕시에의해 1치환 또는 비치환되거나 할로겐에 의해 1 내지 5중 치환된 C1-C3알킬이고, R5및 R6각각은 서로 독립적으로 H 또는 C1-C4알킬이고 ; a는 2 또는 3이고 ; b는 0 또는 1이고 ; X는 산소 또는 황이고 ; R2및 R3각각은 서로 독립적으로 페닐 또는 4-클로로페닐이거나, 또는 R2및 R3는 함께 C1-C4알킬에 의해 비치환, 1치환 또는 2치환된 헤테로싸이클을 질소원자와 함께 형성할 수 있는 C4-C7알킬렌이고, 이 사슬에서 메틸렌기중 하나는 O, S 또는 NR7에 의해 치환될 수 있는 1-아킬-2-니프로알아민.
  3. 제2항에 있어서, R1이 메틸, 염소, 메톡시, 에톡시, 디플루오로매톡시, 메틸렌디옥시, 디플루오로메틸렌디옥시, 에틸렌디옥시, 니트로, 모노 메틸아미노 또는 디메틸아미노이고, R2및 R3가 질소 원자와 함께 하기 라디칼을 형성하는 1-아릴-2-나프로일아민 ;
  4. 제3항에 있어서, R1이 메톡시 또는 메틸렌디옥시이고 a인 1-아릴-2-니프토알아민.
  5. 제4항에 있어서, X가 수소인 1-아릴-2-나프토일아민.
  6. 제5항에 있어서, 하기 일반식(Ia)의 화합물 ;
  7. 제1항에 있어서, R1이 메톡시 또는 메틸이고, a가 2또는 3이고, b가 0이고, X가 황인 1-아릴-2-나프토일아민.
  8. 제7항에 있어서, 하기 일반식(Ib)의 화합물;
  9. 제1항에 있어서, R1이 할로겐, 니트로, C1-C6알킬, C1-C3알콕시, C3-C6시클로알킬, 메틸렌디옥시, 모노플루오로메틸렌디옥시, 디플루오로메틸렌디옥시, 비치환 에틸렌디옥시, 불소에 의해 1 치환 또는 다중 치환된 에틸렌디옥시, 또는 NR5R6이고 ; R5및 R6각각은 서로 독립적으로 H 또는 C1-C4알킬이고 ; a 는 2 또는 3이고 ; b는 0 또는 1이고 ; X는 산소 또는 황이고 ; R2및 R3각각은 서로 독립적으로 수소, 비치환된 C1-C6알킬, C1-C4알콕시, 할로겐 또는 시아노에 의해 치환된 C1-C6알킬 또는 C3-C7알켄일, 페닐 또는 4-클로로페닐이거나, 또는 R2및 R3는 함께 C1-C4알킬에 의해 비피환, 1치환 또는 2치환된 헤테로싸이클을 질소원자와 함께 형성할 수 있는 C4-C7알킬렌이고, 이 사슬에서 메틸렌기중 하나는 O, S 또는 NR7에 의해 치환될 수 있는 화합물인 하기 일반식(Ic)에 해당하는 1-아릴-2-나프토일아민.
    상기식에서, R8및 R9각각은 메톡시 라디칼이거나 또는 R8및 R9는 함께 메틸렌디옥시 라디칼이고, Q는 다음 라디칼
    이다.
  10. 제9항에 있어서, 하기 일반식(ld)의 화합물 ;
  11. 제1항에 있어서, 하기 일반식(le)의 1-아릴-2-나프토일아민 ;
    상기식에서, R8및 R9각각은 메톡시이거나 또는 R8및 R9가 함께 메틸렌디옥시이고, R10및 R11이 메톡시이거나, 또는 R10및 R11이 함께 메틸렌디옥시이거나, 또는 R10이 수소일때 R11은 염소, 니트로, 아미노 또는 아세틸아미노이고, 그리고 X1은 산소 또는 황이다.
  12. 하기 일반식(Ⅱ)의 아민을 a) 하기 일반식(Ⅲ)의 나프토산 유도체에 의해 하기 일반식(Ⅰ')의 화합물로 전환시키고, 필요한 경우 일반식(Ⅰ')의 화합물을 5황화인에 의해 하기 일반식(Ⅰ″)의 티오카본아미드로 전환시키거나, 또는 X가 NH인 일반식(Ⅰ)의 화합물을 얻기 위해서 b) 하기 일반식(Ⅳ)의 아미노 에스테르에 의해 하기 일반식(Ⅰ''')의 화합물로 전환시키는 것을 포함하는 제1항에 따른 일반식(Ⅰ)화합물의 제조방법.
    상기식에서 R1, R2, R3, a 및 b는 일반식(Ⅰ)에서 정의한 바와 같고, Y는 OH, 할로겐 또는 C1-C4알콕시이고, X는 NH이고, 그리고 R13은 C1-C4알킬이다.
  13. 통상의 담체 및 보조제와 함께 활성 성분으로서 1이상의 일반식(Ⅰ)화합물을 포함하는 살균제 조성물.
  14. 제13항에 있어서, 활성 성분으로서 제6항에 따른 일반식(Ia)의 화합물을 포함하는 조성물.
  15. 제13항에 있어서, 활성 성분으로서 제8항에 따른 일반식(Ib)의 화합물을 포함하는 조성물.
  16. 제13항에 있어서, 활성성분으로서 제10항에 따른 일반식(Id)의 화합물을 포함하는 조성물.
  17. 일반식(Ⅰ)화합물의 살균 유효량을 식물 또는 그 부위에 투여하는 것을 포함하는 식물 병원성 미생물의 방제 방법.
  18. 제17항에 있어서, 미생물이 플라스모파라, 벤투리아, 피토프토라, 세프코스포라 또는 에리세페인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890008415A 1988-06-16 1989-06-16 1-아릴-나프토일아민 및 그의 제조방법 KR900000351A (ko)

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PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
CN1429199A (zh) * 2000-10-17 2003-07-09 纳幕尔杜邦公司 杀虫剂1,8－萘二甲酰胺
AU3040102A (en) * 2000-10-17 2002-04-29 Du Pont Insecticidal 1,8-naphthalenedicarboxamides
GB0124934D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124941D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124936D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124931D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124939D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
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GB0124933D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
ATE485275T1 (de) 2002-02-12 2010-11-15 Glaxosmithkline Llc Nicotinamide und deren verwendung als p38 inhibitoren
GB0217757D0 (en) 2002-07-31 2002-09-11 Glaxo Group Ltd Novel compounds
GB0308186D0 (en) 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
GB0308185D0 (en) 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
GB0308201D0 (en) 2003-04-09 2003-05-14 Smithkline Beecham Corp Novel compounds
GB0318814D0 (en) 2003-08-11 2003-09-10 Smithkline Beecham Corp Novel compounds
CA2743391A1 (en) * 2011-05-27 2012-11-27 Queen's University At Kingston Compounds and methods for catalytic directed ortho substitution of aromatic amides and esters

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525595A1 (fr) * 1982-04-27 1983-10-28 Pharmuka Lab Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments
DE3710717A1 (de) * 1987-03-31 1988-10-20 Celamerck Gmbh & Co Kg Bicyclische amide, ihre herstellung und verwendung

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ZA894555B (en) 1990-02-28
EP0346841A2 (de) 1989-12-20
AU3642589A (en) 1989-12-21
JPH0242046A (ja) 1990-02-13
EP0346841A3 (de) 1991-01-09
BR8902915A (pt) 1990-02-01
US4968677A (en) 1990-11-06
DE3919348A1 (de) 1989-12-21
DK296589D0 (da) 1989-06-15
PT90854A (pt) 1989-12-29
DK296589A (da) 1989-12-17

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