ATE275133T1 - 1,2-dihydro-2-oxochinolin-derivate - Google Patents
1,2-dihydro-2-oxochinolin-derivateInfo
- Publication number
- ATE275133T1 ATE275133T1 AT98957145T AT98957145T ATE275133T1 AT E275133 T1 ATE275133 T1 AT E275133T1 AT 98957145 T AT98957145 T AT 98957145T AT 98957145 T AT98957145 T AT 98957145T AT E275133 T1 ATE275133 T1 AT E275133T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- different
- same
- dihydro
- hydrogen atom
- Prior art date
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33253997 | 1997-12-03 | ||
| PCT/JP1998/005451 WO1999028299A1 (en) | 1997-12-03 | 1998-12-03 | 1,2-dihydro-2-oxoquinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275133T1 true ATE275133T1 (de) | 2004-09-15 |
Family
ID=18256057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98957145T ATE275133T1 (de) | 1997-12-03 | 1998-12-03 | 1,2-dihydro-2-oxochinolin-derivate |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6329525B1 (de) |
| EP (1) | EP1048655B1 (de) |
| KR (1) | KR20010032667A (de) |
| CN (1) | CN1118456C (de) |
| AT (1) | ATE275133T1 (de) |
| AU (1) | AU736232B2 (de) |
| CA (1) | CA2313055A1 (de) |
| DE (1) | DE69826034T2 (de) |
| ES (1) | ES2227893T3 (de) |
| WO (1) | WO1999028299A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000256323A (ja) * | 1999-01-08 | 2000-09-19 | Japan Tobacco Inc | ２−オキソキノリン化合物及びその医薬用途 |
| WO2004103974A1 (ja) * | 2003-05-23 | 2004-12-02 | Japan Tobacco Inc. | 置換２－オキソキノリン化合物およびその医薬用途 |
| SE0302323D0 (sv) * | 2003-08-28 | 2003-08-28 | Astrazeneca Ab | Novel compounds |
| WO2005021547A2 (en) * | 2003-08-28 | 2005-03-10 | Pharmaxis Pty Ltd. | Heterocyclic cannabinoid cb2 receptor antagonists |
| WO2008113006A1 (en) * | 2007-03-14 | 2008-09-18 | Xenon Pharmaceuticals Inc. | Methods of using quinolinone compounds in treating sodium channel-mediated diseases or conditions |
| WO2009016841A1 (ja) * | 2007-08-01 | 2009-02-05 | Kumiai Chemical Industry Co., Ltd. | オキソピラジン誘導体及び除草剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2509728A1 (fr) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| JPS63146872A (ja) | 1986-07-08 | 1988-06-18 | Yoshitomi Pharmaceut Ind Ltd | ピリミジニルピペラジン化合物 |
| JPH02152966A (ja) | 1988-12-05 | 1990-06-12 | Otsuka Pharmaceut Co Ltd | ４−ヒドロキシカルボスチリル誘導体 |
| JP3122671B2 (ja) | 1990-05-23 | 2001-01-09 | 協和醗酵工業株式会社 | 複素環式化合物 |
| GB9108547D0 (en) | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| US5206382A (en) | 1991-06-27 | 1993-04-27 | Fidia Georgetown Institute For The Neurosciences | Indole derivatives, pharmaceutical compositions and methods of treating neurological and psychiatric disorders |
| FR2717175B1 (fr) | 1994-03-11 | 1996-06-14 | Adir | Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| JP3888393B2 (ja) | 1995-03-10 | 2007-02-28 | 大正製薬株式会社 | キノロン誘導体 |
| EP1070054A1 (de) * | 1998-04-08 | 2001-01-24 | Takeda Chemical Industries, Ltd. | Aminverbindungen, ihre herstellung und ihre verwendung als somatostatin rezeptor antagonisten oder agonisten |
-
1998
- 1998-12-03 DE DE69826034T patent/DE69826034T2/de not_active Expired - Fee Related
- 1998-12-03 ES ES98957145T patent/ES2227893T3/es not_active Expired - Lifetime
- 1998-12-03 CN CN98811798A patent/CN1118456C/zh not_active Expired - Fee Related
- 1998-12-03 AT AT98957145T patent/ATE275133T1/de not_active IP Right Cessation
- 1998-12-03 KR KR1020007005949A patent/KR20010032667A/ko not_active Ceased
- 1998-12-03 EP EP98957145A patent/EP1048655B1/de not_active Expired - Lifetime
- 1998-12-03 US US09/555,568 patent/US6329525B1/en not_active Expired - Fee Related
- 1998-12-03 CA CA002313055A patent/CA2313055A1/en not_active Abandoned
- 1998-12-03 WO PCT/JP1998/005451 patent/WO1999028299A1/ja not_active Ceased
- 1998-12-03 AU AU13509/99A patent/AU736232B2/en not_active Ceased
-
2001
- 2001-04-10 US US09/829,203 patent/US6380384B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1048655A1 (de) | 2000-11-02 |
| WO1999028299A1 (en) | 1999-06-10 |
| ES2227893T3 (es) | 2005-04-01 |
| EP1048655B1 (de) | 2004-09-01 |
| CA2313055A1 (en) | 1999-06-10 |
| KR20010032667A (ko) | 2001-04-25 |
| DE69826034T2 (de) | 2005-09-08 |
| DE69826034D1 (de) | 2004-10-07 |
| CN1280569A (zh) | 2001-01-17 |
| US6329525B1 (en) | 2001-12-11 |
| US6380384B1 (en) | 2002-04-30 |
| AU1350999A (en) | 1999-06-16 |
| CN1118456C (zh) | 2003-08-20 |
| EP1048655A4 (de) | 2001-04-18 |
| US20020049323A1 (en) | 2002-04-25 |
| HK1034074A1 (en) | 2001-10-12 |
| AU736232B2 (en) | 2001-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |