HUP0303186A2 - 4-Amino-benzopirán-származékok - Google Patents
4-Amino-benzopirán-származékokInfo
- Publication number
- HUP0303186A2 HUP0303186A2 HU0303186A HUP0303186A HUP0303186A2 HU P0303186 A2 HUP0303186 A2 HU P0303186A2 HU 0303186 A HU0303186 A HU 0303186A HU P0303186 A HUP0303186 A HU P0303186A HU P0303186 A2 HUP0303186 A2 HU P0303186A2
- Authority
- HU
- Hungary
- Prior art keywords
- group
- hydrogen atom
- hydrogen atoms
- hydrogen
- alkylthio
- Prior art date
Links
- VGCNVPXAIFXIDF-UHFFFAOYSA-N 2h-chromen-4-amine Chemical class C1=CC=C2C(N)=CCOC2=C1 VGCNVPXAIFXIDF-UHFFFAOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000006624 (C1-C6) alkoxycarbonylamino group Chemical group 0.000 abstract 1
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 150000001562 benzopyrans Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Organic Insulating Materials (AREA)
- Discharging, Photosensitive Material Shape In Electrophotography (AREA)
- External Artificial Organs (AREA)
- Non-Adjustable Resistors (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
A találmány tárgya (I) általános képletű benzopiránszármazékok, R1 ésR2 jelentése egymástól függetlenül 1-6 szénatomos alkilcsoport stb.,R3 jelentése hidroxilcsoport stb., R4 jelentése hidrogénatom stb., R6jelentése hidrogénatom, R7 jelentése hidrogénatom stb., X nincs jelenvagy C=O stb., R8 jelentése hidrogénatom, 1-6 szénatomos alkilcsoportstb., R9 jelentése hidrogénatom vagy nitrocsoport, ha R9 jelentésenitrocsoport, Y jelentése 4-8 szénatomos alkiléncsoport, -(CH2)m-CR11R12-(CH2)n-, vagy -(CH2)O-O-(CH2)p R5 jelentése hidrogénatom,aminocsoport, 1-6 szénatomos alkoxi-, 1-6 szénatomos alkiltiocsoport,1-6 szénatomos alkilamino-, 1-6 szénatomos alkoxikarbonil-amino-csoport stb. vagy gyógyászatilag elfogadható sói. A vegyületetantiaritmiás szerként használhatják. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001036293 | 2001-02-14 | ||
| PCT/JP2002/001236 WO2002064581A1 (en) | 2001-02-14 | 2002-02-14 | 4-aminobenzopyran derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0303186A2 true HUP0303186A2 (hu) | 2003-12-29 |
| HUP0303186A3 HUP0303186A3 (en) | 2007-06-28 |
Family
ID=18899587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0303186A HUP0303186A3 (en) | 2001-02-14 | 2002-02-14 | 4-aminobenzopyran derivatives |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6809114B2 (hu) |
| EP (1) | EP1360182B1 (hu) |
| JP (1) | JP2002316981A (hu) |
| KR (1) | KR100849351B1 (hu) |
| CN (1) | CN1250536C (hu) |
| AT (1) | ATE273294T1 (hu) |
| AU (1) | AU2002232182B2 (hu) |
| CA (1) | CA2436438C (hu) |
| CZ (1) | CZ20032145A3 (hu) |
| DE (1) | DE60200937T2 (hu) |
| HU (1) | HUP0303186A3 (hu) |
| IL (2) | IL156943A0 (hu) |
| NO (1) | NO328708B1 (hu) |
| NZ (1) | NZ527040A (hu) |
| RU (1) | RU2288226C2 (hu) |
| SK (1) | SK287023B6 (hu) |
| TW (1) | TW589305B (hu) |
| UA (1) | UA74052C2 (hu) |
| WO (1) | WO2002064581A1 (hu) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| TWI346112B (en) | 2004-02-25 | 2011-08-01 | Nissan Chemical Ind Ltd | Benzopyran compound |
| AU2005223612B2 (en) | 2004-03-23 | 2010-06-24 | Nissan Chemical Industries, Ltd. | Tricyclic benzopyran compound as anti-arrhythmic agents |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| TW201022223A (en) * | 2008-08-14 | 2010-06-16 | Nissan Chemical Ind Ltd | Di-substituted benzopyrane compound |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (hu) | 2011-07-01 | 2018-04-28 | ||
| AR090037A1 (es) | 2011-11-15 | 2014-10-15 | Xention Ltd | Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio |
| WO2013072693A1 (en) | 2011-11-15 | 2013-05-23 | Xention Limited | Thieno [2, 3 - c] pyrazoles for use as potassium channel inhibitors |
| US20150045305A1 (en) | 2012-01-27 | 2015-02-12 | Gilead Sciences, Inc. | Combination therapies using late sodium ion channel blockers and potassium ion channel blockers |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9005318D0 (en) * | 1990-03-09 | 1990-05-02 | Isis Innovation | Antiarrhythmic agents |
| DE19742508A1 (de) * | 1997-09-26 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
| CZ2002802A3 (cs) * | 1999-09-17 | 2003-02-12 | Nissan Chemical Industries, Ltd. | Benzopyranové deriváty |
| US6555574B1 (en) * | 1999-09-24 | 2003-04-29 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
| US6677371B1 (en) * | 1999-10-05 | 2004-01-13 | Nissan Chemical Industries, Ltd. | 4-oxybenzopyran derivative |
-
2001
- 2001-12-27 TW TW090132570A patent/TW589305B/zh not_active IP Right Cessation
-
2002
- 2002-02-13 JP JP2002034753A patent/JP2002316981A/ja active Pending
- 2002-02-14 CZ CZ20032145A patent/CZ20032145A3/cs unknown
- 2002-02-14 CA CA002436438A patent/CA2436438C/en not_active Expired - Fee Related
- 2002-02-14 AT AT02712344T patent/ATE273294T1/de not_active IP Right Cessation
- 2002-02-14 IL IL15694302A patent/IL156943A0/xx active IP Right Grant
- 2002-02-14 UA UA2003098375A patent/UA74052C2/uk unknown
- 2002-02-14 SK SK1000-2003A patent/SK287023B6/sk not_active IP Right Cessation
- 2002-02-14 CN CNB02804746XA patent/CN1250536C/zh not_active Expired - Fee Related
- 2002-02-14 EP EP02712344A patent/EP1360182B1/en not_active Expired - Lifetime
- 2002-02-14 AU AU2002232182A patent/AU2002232182B2/en not_active Ceased
- 2002-02-14 KR KR1020037010673A patent/KR100849351B1/ko not_active IP Right Cessation
- 2002-02-14 HU HU0303186A patent/HUP0303186A3/hu unknown
- 2002-02-14 RU RU2003127748/04A patent/RU2288226C2/ru not_active IP Right Cessation
- 2002-02-14 NZ NZ527040A patent/NZ527040A/en unknown
- 2002-02-14 WO PCT/JP2002/001236 patent/WO2002064581A1/en active IP Right Grant
- 2002-02-14 US US10/466,175 patent/US6809114B2/en not_active Expired - Fee Related
- 2002-02-14 DE DE60200937T patent/DE60200937T2/de not_active Expired - Lifetime
-
2003
- 2003-07-15 IL IL156943A patent/IL156943A/en not_active IP Right Cessation
- 2003-08-12 NO NO20033561A patent/NO328708B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE273294T1 (de) | 2004-08-15 |
| WO2002064581A1 (en) | 2002-08-22 |
| RU2288226C2 (ru) | 2006-11-27 |
| DE60200937T2 (de) | 2005-07-28 |
| KR100849351B1 (ko) | 2008-07-29 |
| CN1529702A (zh) | 2004-09-15 |
| SK287023B6 (sk) | 2009-09-07 |
| US20040068002A1 (en) | 2004-04-08 |
| TW589305B (en) | 2004-06-01 |
| NO20033561L (no) | 2003-10-14 |
| IL156943A (en) | 2007-05-15 |
| AU2002232182B2 (en) | 2006-09-21 |
| NO20033561D0 (no) | 2003-08-12 |
| CA2436438C (en) | 2009-04-07 |
| IL156943A0 (en) | 2004-02-08 |
| CA2436438A1 (en) | 2002-08-22 |
| HUP0303186A3 (en) | 2007-06-28 |
| UA74052C2 (en) | 2005-10-17 |
| NZ527040A (en) | 2004-04-30 |
| KR20040018334A (ko) | 2004-03-03 |
| DE60200937D1 (de) | 2004-09-16 |
| EP1360182A1 (en) | 2003-11-12 |
| EP1360182B1 (en) | 2004-08-11 |
| RU2003127748A (ru) | 2005-03-20 |
| NO328708B1 (no) | 2010-05-03 |
| CN1250536C (zh) | 2006-04-12 |
| US6809114B2 (en) | 2004-10-26 |
| SK10002003A3 (sk) | 2004-04-06 |
| JP2002316981A (ja) | 2002-10-31 |
| CZ20032145A3 (cs) | 2003-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0303186A2 (hu) | 4-Amino-benzopirán-származékok | |
| NL300877I2 (nl) | obeticholzuur | |
| DK1389617T3 (da) | Heterocyclisk forbindelse og antitumormiddel indeholdende denne som den aktive bestanddel | |
| YU108791A (sh) | Pirazolopirimidinon antianginalna jedinjenja | |
| AP1753A (en) | Thiophene derivatives as antiviral agents for flavvivirus infection | |
| MY130907A (en) | Piperazine compounds as tachykinins antagonists | |
| YU57603A (sh) | Inhibitori fosfodiesteraze 4 | |
| HUP0301514A2 (hu) | Benzimidazol származékok, elżállításuk és ezeket tartalmazó gyógyszerkészítmények | |
| MXPA02012033A (es) | Derivados de 2-aminocarbonil-9h-purina. | |
| NO20101069L (no) | Anvendelse av visse NMDA-affinitetsantagonister som antidepressiva | |
| NO20052074L (no) | Substituerte benzoksazinoner og anvendelser derav. | |
| DE60024471D1 (de) | Benzopyran derivate | |
| BR9510006A (pt) | Derivados de anilina possuindo efeito inibidor de sintase do óxido nítrico | |
| MY139612A (en) | Benzoxazine derivatives as 5-th6 modulators and uses thereof | |
| HK1081194A1 (en) | 6-amino-1h-indazole compounds as phosphodiesterase4 inhibitors, pharmaceutical compositions compris ing the same, and use thereof | |
| EP1304324A4 (en) | SEROTONIN RECAPTURE INHIBITORS | |
| NO20022156L (no) | Kinolin- og naftyridinkarboksylsyre antibakterielle midler | |
| BR0213731A (pt) | Compostos de silìcio | |
| HUP0402341A2 (hu) | Szubsztituált tiazol-2-ilaminokat tartalmazó készítmények rák kezelésére | |
| HUP0202293A2 (hu) | Új N-benzilpiperazin vegyületek, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények | |
| TW200510300A (en) | Amino alcohol compounds | |
| SE0100344D0 (sv) | New Use | |
| YU82302A (sh) | Derivati 2-aminokarbonil-9h-purina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |