NO20020884L - Fremgangsmåte for isolering og rensing av gresspollenallergener - Google Patents

Fremgangsmåte for isolering og rensing av gresspollenallergener

Info

Publication number
NO20020884L
NO20020884L NO20020884A NO20020884A NO20020884L NO 20020884 L NO20020884 L NO 20020884L NO 20020884 A NO20020884 A NO 20020884A NO 20020884 A NO20020884 A NO 20020884A NO 20020884 L NO20020884 L NO 20020884L
Authority
NO
Norway
Prior art keywords
grass pollen
isolating
pollen
pollen allergens
purification
Prior art date
Application number
NO20020884A
Other languages
English (en)
Other versions
NO20020884D0 (no
Inventor
Roland Suck
Oliver Cromwell
Helmut Fiebig
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7919344&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20020884(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20020884D0 publication Critical patent/NO20020884D0/no
Publication of NO20020884L publication Critical patent/NO20020884L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5097—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving plant cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen vedrører en fremgangsmåte for hurtig og effektiv isolering og rensing av fem allergener fra gruppene l, 2, 3, 10 og 13 fra gresspollen. Rensingen av gresspollenet er basert på den oppfinneriske kombinasjon av hydrofob interaksjonskromatografi, gelfiltrering og kationbyrterkromatografi. De således erholdte proteiner kan anvendes ril forbedret diagnostikk av pollenallergier samt til farmasøytiske preparater ved terapi av pollenallergisykdommer.
NO20020884A 1999-08-24 2002-02-22 Fremgangsmåte for isolering og rensing av gresspollenallergener NO20020884L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19939982A DE19939982A1 (de) 1999-08-24 1999-08-24 Verfahren zur Isolierung und Aufreinigung von Gräserpollenallergenen
PCT/EP2000/008059 WO2001013946A2 (de) 1999-08-24 2000-08-18 Verfahren zur isolierung und aufreinigung von gräserpollenallergenen

Publications (2)

Publication Number Publication Date
NO20020884D0 NO20020884D0 (no) 2002-02-22
NO20020884L true NO20020884L (no) 2002-02-22

Family

ID=7919344

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020884A NO20020884L (no) 1999-08-24 2002-02-22 Fremgangsmåte for isolering og rensing av gresspollenallergener

Country Status (20)

Country Link
US (3) US7326769B1 (no)
EP (1) EP1206488B2 (no)
JP (1) JP4942892B2 (no)
KR (1) KR20020019965A (no)
CN (1) CN1205222C (no)
AT (1) ATE297408T1 (no)
AU (1) AU776154B2 (no)
CA (1) CA2381340C (no)
CZ (1) CZ2002500A3 (no)
DE (2) DE19939982A1 (no)
ES (1) ES2241646T5 (no)
HU (1) HUP0203744A2 (no)
MX (1) MXPA02001949A (no)
NO (1) NO20020884L (no)
PL (1) PL205323B1 (no)
PT (1) PT1206488E (no)
RU (1) RU2242248C2 (no)
SK (1) SK2202002A3 (no)
WO (1) WO2001013946A2 (no)
ZA (1) ZA200202288B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102096B4 (de) * 2001-01-18 2007-08-09 BLüCHER GMBH Geruchsadsorbierende Berufsbekleidung
SE0200946D0 (sv) * 2002-03-27 2002-03-27 Pharmacia Diagnostics Ab Novel Allergen
EP1872792A1 (en) * 2006-06-29 2008-01-02 Biotech Tools S.A. A method for the production of hydrolyzed allergen
JP5279238B2 (ja) * 2006-11-16 2013-09-04 森川健康堂株式会社 血圧降下作用を有する花粉の製造方法
EP2152405B2 (de) * 2007-05-25 2017-04-05 Merck Patent GmbH Mischpfropfpolymere für die kationenaustauschchromatographie
CN102675439A (zh) * 2012-03-31 2012-09-19 广州医学院第二附属医院 一种重组黑麦草花粉过敏原与突变体的制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05509230A (ja) * 1990-08-17 1993-12-22 ザ・ユニバーシテイ・オブ・メルボルン ライグラスの花粉のアレルゲン
US5736362A (en) * 1990-10-26 1998-04-07 The University Of Melbourne Ryegrass pollen allergen
AT401937B (de) * 1993-04-01 1996-12-27 Biomay Prod & Handel Rekombinantes lieschgras pollen allergen phl p ii
DE19918682A1 (de) * 1999-04-23 2000-10-26 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens

Also Published As

Publication number Publication date
HUP0203744A2 (hu) 2003-04-28
DE50010525D1 (de) 2005-07-14
US20080118536A1 (en) 2008-05-22
CZ2002500A3 (cs) 2002-05-15
US7326769B1 (en) 2008-02-05
AU6997000A (en) 2001-03-19
SK2202002A3 (en) 2002-06-04
ES2241646T5 (es) 2016-01-22
JP2003507432A (ja) 2003-02-25
NO20020884D0 (no) 2002-02-22
CA2381340C (en) 2015-07-14
US8329185B2 (en) 2012-12-11
PL353349A1 (en) 2003-11-17
DE19939982A1 (de) 2001-03-01
EP1206488B1 (de) 2005-06-08
ZA200202288B (en) 2003-06-20
CN1205222C (zh) 2005-06-08
CA2381340A1 (en) 2001-03-01
US20080118991A1 (en) 2008-05-22
EP1206488B2 (de) 2015-10-14
JP4942892B2 (ja) 2012-05-30
WO2001013946A3 (de) 2001-06-07
ATE297408T1 (de) 2005-06-15
PL205323B1 (pl) 2010-04-30
ES2241646T3 (es) 2005-11-01
MXPA02001949A (es) 2002-11-07
KR20020019965A (ko) 2002-03-13
PT1206488E (pt) 2005-10-31
CN1372567A (zh) 2002-10-02
WO2001013946A2 (de) 2001-03-01
RU2242248C2 (ru) 2004-12-20
AU776154B2 (en) 2004-08-26
EP1206488A2 (de) 2002-05-22

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