DE69923996D1 - Methode für die herstellung von gereinigtem invasinprotein und seine anwendung - Google Patents
Methode für die herstellung von gereinigtem invasinprotein und seine anwendungInfo
- Publication number
- DE69923996D1 DE69923996D1 DE69923996T DE69923996T DE69923996D1 DE 69923996 D1 DE69923996 D1 DE 69923996D1 DE 69923996 T DE69923996 T DE 69923996T DE 69923996 T DE69923996 T DE 69923996T DE 69923996 D1 DE69923996 D1 DE 69923996D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- cleaned
- application
- invasin protein
- highly purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10508598P | 1998-10-21 | 1998-10-21 | |
US13675499P | 1999-06-01 | 1999-06-01 | |
PCT/US1999/024931 WO2000023462A1 (en) | 1998-10-21 | 1999-10-21 | Method for the production of purified invasin protein and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69923996D1 true DE69923996D1 (de) | 2005-04-07 |
Family
ID=26802247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69923996T Expired - Lifetime DE69923996D1 (de) | 1998-10-21 | 1999-10-21 | Methode für die herstellung von gereinigtem invasinprotein und seine anwendung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070202124A1 (de) |
EP (1) | EP1131338B1 (de) |
AT (1) | ATE290012T1 (de) |
AU (1) | AU1227700A (de) |
CA (1) | CA2347937A1 (de) |
DE (1) | DE69923996D1 (de) |
WO (1) | WO2000023462A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0025058D0 (en) * | 2000-10-12 | 2000-11-29 | Smithkline Beecham Biolog | Composition |
CA2548202C (en) * | 2003-11-25 | 2013-05-14 | The Government Of The United States, As Represented By The Secretary Of The Army | Use of shigella invaplex to transport functional proteins and transcriptionally active nucleic acids across mammalian cell membranes in vitro and in vivo |
US7833740B2 (en) | 2005-08-07 | 2010-11-16 | Tgc Biomics Gmbh | Test system for detecting salmonella |
DE102005037796A1 (de) * | 2005-08-07 | 2007-02-08 | Tgc Biomics Gmbh | Testsystem zum Nachweis von Salmonellen |
CN101711165B (zh) * | 2007-03-27 | 2016-02-24 | 以沃尔特里德军事研究所的名义,由美国陆军部部长为代表的美国政府 | 人造侵袭素复合物 |
DE102010018085A1 (de) * | 2010-04-23 | 2011-10-27 | Bioserv Analytik Und Medizinprodukte Gmbh | Verfahren zur Erkennung einer Salmonelleninfektion |
US9492523B2 (en) * | 2011-12-09 | 2016-11-15 | The Board Of Regents For Oklahoma State University | Broadly protective Shigella vaccine based on type III secretion apparatus proteins |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
FR2567541B1 (fr) * | 1984-07-13 | 1987-02-06 | Pasteur Institut | Sonde d'adn et procede pour la detection de " shigelles " et des souches entero-invasives de escherichia coli |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5196338A (en) * | 1986-12-31 | 1993-03-23 | Praxis Biologics, Inc. | Recombinant vectors for Haemophilus influenzae peptides and proteins |
JP2849632B2 (ja) * | 1988-04-08 | 1999-01-20 | 社団法人北里研究所 | ワクチン製剤 |
US5041372A (en) * | 1988-11-02 | 1991-08-20 | The United States Of America As Represented By The Department Of Health And Human Services | Probe to identify enteroinvasive E. coli and Shigella species |
DE3843627A1 (de) * | 1988-12-21 | 1990-07-05 | Inst Genbiologische Forschung | Kartoffelknollenspezifische transkriptionale regulation |
US5594115A (en) * | 1990-04-09 | 1997-01-14 | Pharmacia & Upjohn Company | Process of purifying recombinant proteins and compounds useful in such process |
US5726293A (en) * | 1992-10-02 | 1998-03-10 | The General Hospital Corporation | Affinity purification methods involving imidazole elution |
US5552294A (en) * | 1992-10-20 | 1996-09-03 | Children's Medical Center Corporation | Rapid detection of virulence-associated factors |
US5834247A (en) * | 1992-12-09 | 1998-11-10 | New England Biolabs, Inc. | Modified proteins comprising controllable intervening protein sequences or their elements methods of producing same and methods for purification of a target protein comprised by a modified protein |
US5747024A (en) * | 1993-03-08 | 1998-05-05 | Immunex Corporation | Vaccine adjuvant comprising interleukin-15 |
US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
US6861247B1 (en) * | 1995-11-14 | 2005-03-01 | The General Hospital Corporation | Salmonella secreted proteins and uses thereof |
US5935824A (en) * | 1996-01-31 | 1999-08-10 | Technologene, Inc. | Protein expression system |
US6303302B1 (en) * | 1997-11-19 | 2001-10-16 | The Whitehead Institute For Biomedical Research | Regulation of fungal gene expression |
-
1999
- 1999-10-21 AT AT99970664T patent/ATE290012T1/de not_active IP Right Cessation
- 1999-10-21 AU AU12277/00A patent/AU1227700A/en not_active Abandoned
- 1999-10-21 DE DE69923996T patent/DE69923996D1/de not_active Expired - Lifetime
- 1999-10-21 EP EP99970664A patent/EP1131338B1/de not_active Expired - Lifetime
- 1999-10-21 WO PCT/US1999/024931 patent/WO2000023462A1/en active IP Right Grant
- 1999-10-21 CA CA002347937A patent/CA2347937A1/en not_active Abandoned
-
2007
- 2007-03-07 US US11/683,221 patent/US20070202124A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2347937A1 (en) | 2000-04-27 |
US20070202124A1 (en) | 2007-08-30 |
EP1131338A1 (de) | 2001-09-12 |
ATE290012T1 (de) | 2005-03-15 |
WO2000023462A1 (en) | 2000-04-27 |
EP1131338A4 (de) | 2002-08-28 |
EP1131338B1 (de) | 2005-03-02 |
AU1227700A (en) | 2000-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |