NO20015864L - Blokkerende monoklonalt antistoff mot VLA-1 samt anvendelse derav ved behandling av inflammatoriske lidelser - Google Patents

Blokkerende monoklonalt antistoff mot VLA-1 samt anvendelse derav ved behandling av inflammatoriske lidelser

Info

Publication number
NO20015864L
NO20015864L NO20015864A NO20015864A NO20015864L NO 20015864 L NO20015864 L NO 20015864L NO 20015864 A NO20015864 A NO 20015864A NO 20015864 A NO20015864 A NO 20015864A NO 20015864 L NO20015864 L NO 20015864L
Authority
NO
Norway
Prior art keywords
vla
treatment
monoclonal antibody
inflammatory disorders
blocking monoclonal
Prior art date
Application number
NO20015864A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015864D0 (no
Inventor
Antonin De Fougerolles
Philip Gotwals
Roy R Lobb
Victor Koteliansky
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of NO20015864D0 publication Critical patent/NO20015864D0/no
Publication of NO20015864L publication Critical patent/NO20015864L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Animal Behavior & Ethology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
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  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
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  • Urology & Nephrology (AREA)
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NO20015864A 1999-06-01 2001-11-30 Blokkerende monoklonalt antistoff mot VLA-1 samt anvendelse derav ved behandling av inflammatoriske lidelser NO20015864L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13703899P 1999-06-01 1999-06-01
US18533600P 2000-02-29 2000-02-29
PCT/US2000/015004 WO2000072881A1 (en) 1999-06-01 2000-06-01 A blocking monoclonal antibody to vla-1 and its use for the treatment of inflammatory disorders

Publications (2)

Publication Number Publication Date
NO20015864D0 NO20015864D0 (no) 2001-11-30
NO20015864L true NO20015864L (no) 2002-02-01

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NO20015864A NO20015864L (no) 1999-06-01 2001-11-30 Blokkerende monoklonalt antistoff mot VLA-1 samt anvendelse derav ved behandling av inflammatoriske lidelser

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Country Link
US (5) US6955810B2 (enExample)
EP (3) EP1181054A1 (enExample)
JP (6) JP4817503B2 (enExample)
CN (1) CN1309419C (enExample)
AU (2) AU783989B2 (enExample)
BG (1) BG65579B1 (enExample)
BR (1) BR0011250A (enExample)
CA (1) CA2375827C (enExample)
CY (1) CY1116042T1 (enExample)
CZ (1) CZ300710B6 (enExample)
DK (2) DK1488806T3 (enExample)
EA (1) EA011384B1 (enExample)
EE (1) EE200100651A (enExample)
ES (2) ES2557768T3 (enExample)
GE (1) GEP20063774B (enExample)
HK (1) HK1043320A1 (enExample)
HU (1) HUP0202568A3 (enExample)
IL (2) IL146508A0 (enExample)
IS (1) IS6179A (enExample)
MX (1) MXPA01012388A (enExample)
NO (1) NO20015864L (enExample)
NZ (1) NZ515686A (enExample)
PT (2) PT1488806E (enExample)
SI (2) SI1488806T1 (enExample)
SK (1) SK17232001A3 (enExample)
TR (1) TR200103432T2 (enExample)
WO (1) WO2000072881A1 (enExample)
YU (1) YU85501A (enExample)

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AU2009245724A1 (en) * 2008-05-09 2009-11-12 Ablynx N.V. Amino acid sequences directed against integrins and uses thereof
CN102946904A (zh) * 2010-06-18 2013-02-27 埃克斯生物科技公司 关节炎治疗
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