NO20013115L - En kombinasjon av FBPase inhibitorer og insulinsensibilisatorer for behandling av diabetes - Google Patents

En kombinasjon av FBPase inhibitorer og insulinsensibilisatorer for behandling av diabetes

Info

Publication number
NO20013115L
NO20013115L NO20013115A NO20013115A NO20013115L NO 20013115 L NO20013115 L NO 20013115L NO 20013115 A NO20013115 A NO 20013115A NO 20013115 A NO20013115 A NO 20013115A NO 20013115 L NO20013115 L NO 20013115L
Authority
NO
Norway
Prior art keywords
diabetes
treatment
combination
insulin
insulin sensitizers
Prior art date
Application number
NO20013115A
Other languages
English (en)
Other versions
NO20013115D0 (no
Inventor
Mark D Erion
Paul Van Poelje
Original Assignee
Metabasis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabasis Therapeutics Inc filed Critical Metabasis Therapeutics Inc
Publication of NO20013115D0 publication Critical patent/NO20013115D0/no
Publication of NO20013115L publication Critical patent/NO20013115L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
NO20013115A 1998-12-24 2001-06-21 En kombinasjon av FBPase inhibitorer og insulinsensibilisatorer for behandling av diabetes NO20013115L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11471898P 1998-12-24 1998-12-24
PCT/US1999/030713 WO2000038666A2 (en) 1998-12-24 1999-12-22 A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES

Publications (2)

Publication Number Publication Date
NO20013115D0 NO20013115D0 (no) 2001-06-21
NO20013115L true NO20013115L (no) 2001-08-24

Family

ID=22357016

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013115A NO20013115L (no) 1998-12-24 2001-06-21 En kombinasjon av FBPase inhibitorer og insulinsensibilisatorer for behandling av diabetes

Country Status (25)

Country Link
EP (1) EP1143955B1 (no)
JP (1) JP2003515523A (no)
KR (3) KR100689943B1 (no)
CN (3) CN100352505C (no)
AT (1) ATE300288T1 (no)
AU (1) AU771039B2 (no)
BR (1) BR9917005A (no)
CA (1) CA2354053A1 (no)
CZ (1) CZ20012353A3 (no)
DE (1) DE69926400T2 (no)
DK (1) DK1143955T3 (no)
ES (1) ES2246586T3 (no)
HK (1) HK1046863B (no)
HU (1) HUP0402506A3 (no)
ID (1) ID30237A (no)
IL (2) IL143569A0 (no)
MX (1) MXPA01006511A (no)
NO (1) NO20013115L (no)
NZ (1) NZ512219A (no)
PL (1) PL352756A1 (no)
PT (1) PT1143955E (no)
RU (2) RU2227749C2 (no)
SK (1) SK9172001A3 (no)
WO (1) WO2000038666A2 (no)
ZA (1) ZA200105016B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6452098A (en) 1997-03-07 1998-09-22 Metabasis Therapeutics, Inc. Novel purine inhibitors of fructose-1,6-bisphosphatase
US6312662B1 (en) 1998-03-06 2001-11-06 Metabasis Therapeutics, Inc. Prodrugs phosphorus-containing compounds
KR100818845B1 (ko) 1998-09-09 2008-04-01 메타베이시스 테라퓨틱스, 인크. 신규한 프럭토스 1,6-비스포스파타제의 헤테로방향족 억제제
PL356525A1 (en) 1999-12-22 2004-06-28 Metabasis Therapeutics, Inc. Novel bisamidate phosphonate prodrugs
WO2001066553A2 (en) 2000-03-08 2001-09-13 Metabasis Therapeutics, Inc. Novel aryl fructose-1,6-bisphosphatase inhibitors
KR100854851B1 (ko) * 2000-07-06 2008-08-27 메타베이시스 테라퓨틱스, 인크. 당뇨병 치료에 유용한 FBPase 억제제와 항당뇨제의조합물
AU2002215218A1 (en) * 2000-11-17 2002-05-27 Takeda Chemical Industries Ltd. Isoxazole derivatives
JP4332496B2 (ja) 2002-05-13 2009-09-16 メタバシス・セラピューティクス・インコーポレイテッド Pmeaおよびpmpa環生成合成
JP4476811B2 (ja) 2002-05-13 2010-06-09 メタバシス・セラピューティクス・インコーポレイテッド Pmeaおよびそのアナログの新規ホスホン酸系プロドラッグ
WO2004022083A1 (en) * 2002-09-04 2004-03-18 Dsm Ip Assets B.V. A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
JP4921162B2 (ja) * 2003-02-11 2012-04-25 ヴァーナリス(ケンブリッジ)リミテッド 熱ショックタンパク質の阻害剤としてのイソオキサゾール化合物類
EA013249B1 (ru) 2003-12-26 2010-04-30 Киова Хакко Кирин Ко., Лтд. Производные тиазола
CA2577373A1 (en) * 2004-08-18 2006-03-02 Metabasis Therapeutics, Inc. Novel thiazole inhibitors of fructose 1,6-bisphosphatase
TW200633720A (en) * 2004-12-13 2006-10-01 Sankyo Co Medicinal composition for diabetic
CA2591416A1 (en) * 2004-12-15 2006-06-22 Daiichi Sankyo Company Limited Medicinal composition containing fbpase inhibitor
WO2006126673A1 (ja) * 2005-05-27 2006-11-30 Daiichi Sankyo Company, Limited 組み合わせによる糖尿病治療薬
EP1894930A4 (en) 2005-06-23 2010-06-23 Kyowa Hakko Kirin Co Ltd THIAZOLE DERIVATIVE
EP2089017A2 (en) 2006-11-02 2009-08-19 Aestus Therapeutics, Inc. Methods of treating neuropathic pain by modulation of glycogenolysis or glycolysis pathways
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
US9631825B2 (en) 2012-12-18 2017-04-25 Nortek Air Solutions, Llc Air filter assembly
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
WO2016003812A1 (en) 2014-07-02 2016-01-07 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
CN105481896A (zh) * 2015-12-03 2016-04-13 浙江大学 一种地马格列的制备方法
CN113416739B (zh) * 2021-06-24 2022-04-19 黑龙江八一农垦大学 鲁氏酵母菌基因在提高微生物产hdmf的产量中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968790A (en) * 1988-08-12 1990-11-06 American Cyanamid Company Antidiabetic phosphates
JPH03157377A (ja) * 1988-11-18 1991-07-05 Takeda Chem Ind Ltd チオ尿素誘導体及びage生成阻害剤
EP0427799B1 (en) * 1989-01-24 1994-11-30 Gensia, Inc. Method and compounds for aica riboside delivery and for lowering blood glucose
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5859037A (en) * 1997-02-19 1999-01-12 Warner-Lambert Company Sulfonylurea-glitazone combinations for diabetes
AU6691798A (en) * 1997-03-07 1998-09-22 Metabasis Therapeutics, Inc. Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
ATE253073T1 (de) * 1997-03-07 2003-11-15 Metabasis Therapeutics Inc Neue benzimidazol inhibitoren der fructose-1,6- bisphosphatase
AU6452098A (en) * 1997-03-07 1998-09-22 Metabasis Therapeutics, Inc. Novel purine inhibitors of fructose-1,6-bisphosphatase

Also Published As

Publication number Publication date
CN1350466A (zh) 2002-05-22
AU771039B2 (en) 2004-03-11
DE69926400T2 (de) 2006-05-24
EP1143955A3 (en) 2002-08-28
HK1046863B (zh) 2008-07-25
NO20013115D0 (no) 2001-06-21
PT1143955E (pt) 2005-11-30
BR9917005A (pt) 2002-04-02
CA2354053A1 (en) 2000-07-06
HUP0402506A3 (en) 2007-05-29
CN101164618A (zh) 2008-04-23
DK1143955T3 (da) 2005-11-14
ES2246586T3 (es) 2006-02-16
CZ20012353A3 (cs) 2001-12-12
RU2227749C2 (ru) 2004-04-27
KR20060114724A (ko) 2006-11-07
ZA200105016B (en) 2002-09-19
NZ512219A (en) 2004-12-24
IL143569A (en) 2006-06-11
WO2000038666A3 (en) 2001-11-29
PL352756A1 (en) 2003-09-08
IL143569A0 (en) 2002-04-21
ATE300288T1 (de) 2005-08-15
JP2003515523A (ja) 2003-05-07
SK9172001A3 (en) 2002-04-04
KR20010099942A (ko) 2001-11-09
MXPA01006511A (es) 2004-03-19
KR100689943B1 (ko) 2007-03-08
AU2058300A (en) 2000-07-31
HUP0402506A2 (hu) 2005-04-28
CN100352505C (zh) 2007-12-05
EP1143955B1 (en) 2005-07-27
KR20070046210A (ko) 2007-05-02
RU2003132054A (ru) 2005-04-20
DE69926400D1 (de) 2005-09-01
ID30237A (id) 2001-11-15
HK1046863A1 (en) 2003-01-30
CN1714866A (zh) 2006-01-04
EP1143955A2 (en) 2001-10-17
WO2000038666A2 (en) 2000-07-06

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