MXPA01006511A - Combinacion de inhibidores de fb-pasa y sensibilizadores de insulina para el tratamiento de diabetes. - Google Patents
Combinacion de inhibidores de fb-pasa y sensibilizadores de insulina para el tratamiento de diabetes.Info
- Publication number
- MXPA01006511A MXPA01006511A MXPA01006511A MXPA01006511A MXPA01006511A MX PA01006511 A MXPA01006511 A MX PA01006511A MX PA01006511 A MXPA01006511 A MX PA01006511A MX PA01006511 A MXPA01006511 A MX PA01006511A MX PA01006511 A MXPA01006511 A MX PA01006511A
- Authority
- MX
- Mexico
- Prior art keywords
- diabetes
- treatment
- combination
- insulin
- insulin sensitizers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Se proporcionan composiciones farmaceuticas que contienen un inhibidor de FBPasa y un sensibilizador de insulina asi como tambien metodos para el tratamiento de diabetes y enfermedades que responden al control glicemico incrementado, un mejoramiento en la sensibilidad a la insulina, una reduccion en los niveles de insulina, o un aumento de la secrecion de insulina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11471898P | 1998-12-24 | 1998-12-24 | |
| PCT/US1999/030713 WO2000038666A2 (en) | 1998-12-24 | 1999-12-22 | A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA01006511A true MXPA01006511A (es) | 2004-03-19 |
Family
ID=22357016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA01006511A MXPA01006511A (es) | 1998-12-24 | 1999-12-22 | Combinacion de inhibidores de fb-pasa y sensibilizadores de insulina para el tratamiento de diabetes. |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1143955B1 (es) |
| JP (1) | JP2003515523A (es) |
| KR (3) | KR20070046210A (es) |
| CN (3) | CN100352505C (es) |
| AT (1) | ATE300288T1 (es) |
| AU (1) | AU771039B2 (es) |
| BR (1) | BR9917005A (es) |
| CA (1) | CA2354053A1 (es) |
| CZ (1) | CZ20012353A3 (es) |
| DE (1) | DE69926400T2 (es) |
| DK (1) | DK1143955T3 (es) |
| ES (1) | ES2246586T3 (es) |
| HK (1) | HK1046863B (es) |
| HU (1) | HUP0402506A3 (es) |
| ID (1) | ID30237A (es) |
| IL (2) | IL143569A0 (es) |
| MX (1) | MXPA01006511A (es) |
| NO (1) | NO20013115L (es) |
| NZ (1) | NZ512219A (es) |
| PL (1) | PL352756A1 (es) |
| PT (1) | PT1143955E (es) |
| RU (2) | RU2227749C2 (es) |
| SK (1) | SK9172001A3 (es) |
| WO (1) | WO2000038666A2 (es) |
| ZA (1) | ZA200105016B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6452098A (en) | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
| US6312662B1 (en) | 1998-03-06 | 2001-11-06 | Metabasis Therapeutics, Inc. | Prodrugs phosphorus-containing compounds |
| HUP0103143A3 (en) | 1998-09-09 | 2003-01-28 | Metabasis Therapeutics Inc San | Novel heteroaromatic inhibitors of fructose 1,6-bisphosphatase, process for their preparation and their use |
| CN100595204C (zh) * | 1999-12-22 | 2010-03-24 | 症变治疗公司 | 双氨基化膦酸酯前药 |
| CA2401706A1 (en) | 2000-03-08 | 2001-09-13 | Metabasis Therapeutics, Inc. | Novel aryl fructose-1,6-bisphosphatase inhibitors |
| RU2328308C2 (ru) * | 2000-07-06 | 2008-07-10 | Метабэйсис Терапьютикс, Инк. | Комбинирование ингибиторов fbp-азы и антидиабетических средств для лечения диабета |
| EP1340749A4 (en) | 2000-11-17 | 2007-09-05 | Takeda Pharmaceutical | isoxazole |
| NZ536328A (en) | 2002-05-13 | 2007-11-30 | Metabasis Therapeutics Inc | Novel phosphonic acid based prodrugs of PMEA and its analogues |
| JP4332496B2 (ja) | 2002-05-13 | 2009-09-16 | メタバシス・セラピューティクス・インコーポレイテッド | Ｐｍｅａおよびｐｍｐａ環生成合成 |
| EP1534314B1 (en) * | 2002-09-04 | 2014-10-22 | DSM IP Assets B.V. | A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction |
| UA80991C2 (en) | 2002-10-07 | 2007-11-26 | Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes | |
| JP4921162B2 (ja) * | 2003-02-11 | 2012-04-25 | ヴァーナリス（ケンブリッジ）リミテッド | 熱ショックタンパク質の阻害剤としてのイソオキサゾール化合物類 |
| HUE025659T2 (en) | 2003-12-26 | 2016-04-28 | Kyowa Hakko Kirin Co Ltd | Thiazole derivatives |
| EP1778250A2 (en) * | 2004-08-18 | 2007-05-02 | Metabasis Therapeutics, Inc. | Novel thiazole inhibitors of fructose 1,6-bisphosphatase |
| CN101119748A (zh) * | 2004-12-13 | 2008-02-06 | 第一三共株式会社 | 用于治疗糖尿病的药物组合物 |
| CA2591416A1 (en) * | 2004-12-15 | 2006-06-22 | Daiichi Sankyo Company Limited | Medicinal composition containing fbpase inhibitor |
| TW200722088A (en) * | 2005-05-27 | 2007-06-16 | Sankyo Co | Diabetes remedy |
| JPWO2006137527A1 (ja) | 2005-06-23 | 2009-01-22 | 協和発酵キリン株式会社 | チアゾール誘導体 |
| US20100222304A1 (en) | 2006-11-02 | 2010-09-02 | Lillian W Chiang | Methods of Treating Neuropathic Pain by Modulation of Glycogenolysis or Glycolysis |
| CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
| US9631825B2 (en) | 2012-12-18 | 2017-04-25 | Nortek Air Solutions, Llc | Air filter assembly |
| EP3623364A1 (en) | 2014-02-13 | 2020-03-18 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
| CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
| CN105481896A (zh) * | 2015-12-03 | 2016-04-13 | 浙江大学 | 一种地马格列的制备方法 |
| CN113416739B (zh) * | 2021-06-24 | 2022-04-19 | 黑龙江八一农垦大学 | 鲁氏酵母菌基因在提高微生物产hdmf的产量中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4968790A (en) * | 1988-08-12 | 1990-11-06 | American Cyanamid Company | Antidiabetic phosphates |
| JPH03157377A (ja) * | 1988-11-18 | 1991-07-05 | Takeda Chem Ind Ltd | チオ尿素誘導体及びａｇｅ生成阻害剤 |
| CA2008325A1 (en) * | 1989-01-24 | 1990-07-24 | Harry E. Gruber | Method and compounds for aica riboside delivery and for lowering blood glucose |
| TW438587B (en) * | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
| AU6452098A (en) * | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
| DE69819311T2 (de) * | 1997-03-07 | 2004-07-29 | Metabasis Therapeutics Inc., San Diego | Neue benzimidazol inhibitoren der fructose-1,6-bisphosphatase |
| AU6691798A (en) * | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase |
-
1999
- 1999-12-22 CA CA002354053A patent/CA2354053A1/en not_active Abandoned
- 1999-12-22 KR KR1020077008649A patent/KR20070046210A/ko not_active Application Discontinuation
- 1999-12-22 DE DE69926400T patent/DE69926400T2/de not_active Expired - Lifetime
- 1999-12-22 DK DK99964313T patent/DK1143955T3/da active
- 1999-12-22 ES ES99964313T patent/ES2246586T3/es not_active Expired - Lifetime
- 1999-12-22 EP EP99964313A patent/EP1143955B1/en not_active Expired - Lifetime
- 1999-12-22 KR KR1020017008102A patent/KR100689943B1/ko not_active IP Right Cessation
- 1999-12-22 PL PL99352756A patent/PL352756A1/xx not_active Application Discontinuation
- 1999-12-22 WO PCT/US1999/030713 patent/WO2000038666A2/en active Application Filing
- 1999-12-22 CN CNB998163562A patent/CN100352505C/zh not_active Expired - Fee Related
- 1999-12-22 CZ CZ20012353A patent/CZ20012353A3/cs unknown
- 1999-12-22 SK SK917-2001A patent/SK9172001A3/sk unknown
- 1999-12-22 CN CNA2007101628889A patent/CN101164618A/zh active Pending
- 1999-12-22 JP JP2000590620A patent/JP2003515523A/ja active Pending
- 1999-12-22 ID IDW00200101612A patent/ID30237A/id unknown
- 1999-12-22 NZ NZ512219A patent/NZ512219A/xx not_active IP Right Cessation
- 1999-12-22 BR BR9917005-1A patent/BR9917005A/pt not_active Application Discontinuation
- 1999-12-22 AU AU20583/00A patent/AU771039B2/en not_active Ceased
- 1999-12-22 HU HU0402506A patent/HUP0402506A3/hu active IP Right Revival
- 1999-12-22 IL IL14356999A patent/IL143569A0/xx active IP Right Grant
- 1999-12-22 CN CNA2005100806150A patent/CN1714866A/zh active Pending
- 1999-12-22 RU RU2001120726/15A patent/RU2227749C2/ru not_active IP Right Cessation
- 1999-12-22 AT AT99964313T patent/ATE300288T1/de active
- 1999-12-22 PT PT99964313T patent/PT1143955E/pt unknown
- 1999-12-22 KR KR1020067022095A patent/KR20060114724A/ko not_active Application Discontinuation
- 1999-12-22 MX MXPA01006511A patent/MXPA01006511A/es active IP Right Grant
-
2001
- 2001-06-05 IL IL143569A patent/IL143569A/en not_active IP Right Cessation
- 2001-06-19 ZA ZA200105016A patent/ZA200105016B/en unknown
- 2001-06-21 NO NO20013115A patent/NO20013115L/no not_active Application Discontinuation
-
2002
- 2002-11-22 HK HK02108475.5A patent/HK1046863B/zh not_active IP Right Cessation
-
2003
- 2003-10-31 RU RU2003132054/14A patent/RU2003132054A/ru not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1046863A1 (en) | A combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes | |
| DK1373215T3 (da) | Gelanamycinderivater egnet til behandling af cancer | |
| HK1070575A1 (en) | Use of botulinum toxin for treating cardiovasculardiseases | |
| HK1059213A1 (en) | Treatment of type 2 diabetes with inhibitors of dipetidyl peptidase iv | |
| MY151032A (en) | Treatment of tnf? related disorders | |
| SG146653A1 (en) | Methods and reagents for the treatment of immunoinflammatory disorders | |
| JO2373B1 (en) | W-carboxy-aryl diphenyl urease substitutes used as RAV inhibitors | |
| UA85041C2 (ru) | Способ лечения кишечной непроходимости | |
| AU7371600A (en) | Use of alpha-linolenic acid metabolites for treatment or prevention of cancer | |
| IL187254A (en) | ANTISENSE NUCLEOTIDES, COMPOSITIONS COMPRISING THEREOF AND THEIR USE IN MODULATING ACTIVATION OF NF-kB | |
| WO2002078639A3 (en) | A method of treating proliferative diseases using eg5 inhibitors | |
| PL1694354T3 (pl) | Sposób zapobiegania i leczenia cukrzycy za pomocą neurturyny | |
| BG105264A (en) | New use of taxoid derivatives | |
| IL186356A0 (en) | Method of treating of preventing type-2 diabetes | |
| WO2003035048A3 (en) | Methods for the treatment of osteoarthritis and compositions thereof | |
| WO2005013802A3 (en) | Trefoil factor 3 (tff3) as a target for anti-cancer therapy | |
| WO2003103601A3 (en) | DIAGNOSIS AND TREATMENT METHODS FOR DIABETES AND INSULIN RESISTANCE | |
| AU5890499A (en) | Use of composition in the treatment of schizophrenia | |
| UA35854A (uk) | Спосіб лікування приховано протікаючого силікотуберкульозу | |
| UA36341A (uk) | Спосіб лікування запальних процесів навколозубних тканин | |
| UA30659A (uk) | Спосіб купіровання опіатної залежності | |
| UA32255A (uk) | Спосіб лікування цукрового діабету |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |