NO20006600L - Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer - Google Patents

Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer

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Publication number
NO20006600L
NO20006600L NO20006600A NO20006600A NO20006600L NO 20006600 L NO20006600 L NO 20006600L NO 20006600 A NO20006600 A NO 20006600A NO 20006600 A NO20006600 A NO 20006600A NO 20006600 L NO20006600 L NO 20006600L
Authority
NO
Norway
Prior art keywords
vla
autoimmune
inflammatory
treatment
cell binding
Prior art date
Application number
NO20006600A
Other languages
English (en)
Norwegian (no)
Other versions
NO20006600D0 (no
Inventor
Allen Jacob Duplantier
Anthony John Milici
Louis Stanley Chupak
Original Assignee
Pfizer Prod Inc
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Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20006600D0 publication Critical patent/NO20006600D0/no
Publication of NO20006600L publication Critical patent/NO20006600L/no

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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NO20006600A 1998-06-30 2000-12-22 Ikke-peptidylinhibitorer av VLA-4-avhengig cellebinding nyttig for behandling av inflammatoriske, autoimmune og respiratoriske sykdommer NO20006600L (no)

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US9118098P 1998-06-30 1998-06-30
PCT/IB1999/000973 WO2000000477A1 (en) 1998-06-30 1999-05-31 Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases

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US6518292B1 (en) * 1999-03-12 2003-02-11 Bristol-Myers Squibb Co. Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
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US6756378B2 (en) * 1999-06-30 2004-06-29 Pharmacopeia Drug Discovery, Inc. VLA-4 inhibitor compounds
JP2003519697A (ja) 1999-12-28 2003-06-24 ファイザー・プロダクツ・インク 炎症性疾患、自己免疫疾患および呼吸器疾患の処置に有用な非ペプチド系のｖｌａ−４依存性細胞結合阻害薬
AU2001234741A1 (en) * 2000-02-04 2001-08-14 Biogen, Inc. Integrin antagonists
CA2413418A1 (en) 2000-06-21 2001-12-27 Joseph B. Santella Piperidine amides as modulators of chemokine receptor activity
WO2002010140A2 (en) 2000-08-01 2002-02-07 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Imidazolyl derivatives
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
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DE10111877A1 (de) * 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CA2446136C (en) * 2001-05-03 2011-07-05 Galileo Pharmaceuticals, Inc. Pyruvate derivatives
DE60224664T2 (de) * 2001-06-06 2009-01-08 Aventis Pharma Ltd., West Malling Substituierte tetrhydroisochinolin-derivate zur behandlung von entzündlichen erkrankungen
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
US6974869B2 (en) * 2001-09-18 2005-12-13 Bristol-Myers Squibb Pharma Company Piperizinones as modulators of chemokine receptor activity
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GT199900101A (es) 2000-12-16
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TNSN99110A1 (fr) 2005-11-10
PL345308A1 (en) 2001-12-03
IL139584A0 (en) 2002-02-10
TR200003848T2 (tr) 2001-06-21
OA11577A (en) 2004-07-26
JP2002519344A (ja) 2002-07-02
US6355662B1 (en) 2002-03-12
SK20052000A3 (sk) 2002-08-06
WO2000000477A1 (en) 2000-01-06
UA66864C2 (uk) 2004-06-15
ATE311371T1 (de) 2005-12-15
EA200001238A1 (ru) 2001-08-27
HRP20000917A2 (en) 2002-02-28
IS5720A (is) 2000-11-21
AR015312A1 (es) 2001-04-18
KR20010083081A (ko) 2001-08-31
CN1308616A (zh) 2001-08-15
BG105190A (en) 2001-12-29
ID27414A (id) 2001-04-05
ZA993777B (en) 2000-12-04
EP1091943A1 (en) 2001-04-18
DE69928667D1 (de) 2006-01-05
EP1091943B1 (en) 2005-11-30
US6306887B1 (en) 2001-10-23
PE20000762A1 (es) 2000-08-24
EA004792B1 (ru) 2004-08-26
NZ508033A (en) 2002-12-20
HN1999000099A (es) 1999-11-11
PA8477001A1 (es) 2000-05-24
CO5320599A1 (es) 2003-09-30
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