NO20005922L - Nye dihydrofuro[3,4-6]-kinolin-1-onforbindelser,fremgangsmåte ved deres fremstilling og farmasöytiske sammensetningerinneholdende dem - Google Patents
Nye dihydrofuro[3,4-6]-kinolin-1-onforbindelser,fremgangsmåte ved deres fremstilling og farmasöytiske sammensetningerinneholdende demInfo
- Publication number
- NO20005922L NO20005922L NO20005922A NO20005922A NO20005922L NO 20005922 L NO20005922 L NO 20005922L NO 20005922 A NO20005922 A NO 20005922A NO 20005922 A NO20005922 A NO 20005922A NO 20005922 L NO20005922 L NO 20005922L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- aryl
- nr5r6
- heteroaryl
- alkoxy
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- 125000003118 aryl group Chemical group 0.000 abstract 8
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000001072 heteroaryl group Chemical group 0.000 abstract 5
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 4
- 229910052717 sulfur Inorganic materials 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 125000006684 polyhaloalkyl group Polymers 0.000 abstract 3
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000002950 monocyclic group Chemical group 0.000 abstract 2
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 2
- 101100440695 Dictyostelium discoideum corB gene Proteins 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- -1 biphenylyl Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 238000005580 one pot reaction Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9914771A FR2801310B1 (fr) | 1999-11-24 | 1999-11-24 | NOUVEAUX DERIVES DE DIHYDROFURO-[3,4-b]QUINOLEIN-1-ONES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005922D0 NO20005922D0 (no) | 2000-11-23 |
| NO20005922L true NO20005922L (no) | 2001-05-25 |
Family
ID=9552476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005922A NO20005922L (no) | 1999-11-24 | 2000-11-23 | Nye dihydrofuro[3,4-6]-kinolin-1-onforbindelser,fremgangsmåte ved deres fremstilling og farmasöytiske sammensetningerinneholdende dem |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6548515B1 (de) |
| EP (1) | EP1103554B9 (de) |
| JP (1) | JP3566649B2 (de) |
| KR (1) | KR100433705B1 (de) |
| CN (1) | CN1157394C (de) |
| AT (1) | ATE234305T1 (de) |
| AU (1) | AU781300B2 (de) |
| BR (1) | BR0005557A (de) |
| CA (1) | CA2326710C (de) |
| DE (1) | DE60001622T2 (de) |
| DK (1) | DK1103554T5 (de) |
| EA (1) | EA003996B1 (de) |
| ES (1) | ES2194692T3 (de) |
| FR (1) | FR2801310B1 (de) |
| HU (1) | HUP0004704A3 (de) |
| MX (1) | MXPA00011240A (de) |
| NO (1) | NO20005922L (de) |
| NZ (1) | NZ508390A (de) |
| PL (1) | PL344100A1 (de) |
| SI (1) | SI1103554T1 (de) |
| ZA (1) | ZA200006912B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2825091B1 (fr) * | 2001-05-23 | 2003-07-04 | Servier Lab | Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2825092B1 (fr) * | 2001-05-23 | 2005-01-14 | Servier Lab | Nouveau derives trycicliques de dihydro-quinoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CN100376582C (zh) * | 2006-04-26 | 2008-03-26 | 浙江大学 | 一种六氢呋喃[3,2-c]喹啉衍生物的制备方法 |
| CN101092419B (zh) * | 2006-06-23 | 2010-05-12 | 北京师范大学 | (1z,4z,5z)-6-n-烷基-6-氮杂-2-氧代-3-氧杂-4-甲氧基-双环[3.1.0]己烷及其制备方法和用途 |
| CN101092420B (zh) * | 2006-06-23 | 2010-08-25 | 北京师范大学 | (1z,4e,5z)-6-n-异丙基-6-氮杂-2-氧代-3-氧杂-4-甲氧基-双环[3.1.0]己烷及其制备方法和用途 |
| EP2649078B1 (de) | 2010-12-06 | 2016-07-27 | Council of Scientific & Industrial Research | 4-aza-2,3-didehydropodophyllotoxin-verbindungen und verfahren zu ihrer herstellung |
| US9783547B2 (en) | 2014-01-15 | 2017-10-10 | Centre National De La Recherche Scientifique (Cnrs) | Water soluble 4-azapodophyllotoxin analogs |
| WO2017151947A1 (en) * | 2016-03-02 | 2017-09-08 | George Robert Pettit | 4-azapodophylotoxins compounds |
| CN110256457A (zh) * | 2019-06-21 | 2019-09-20 | 江苏师范大学 | 一种4,7-二氢噻吩并[3,4-b]吡啶-5(1H)-酮化合物的合成方法 |
| CN110684033B (zh) * | 2019-09-06 | 2021-05-11 | 广西师范大学 | 四氢呋喃二喹啉化合物及其合成方法和应用 |
| US20230003715A1 (en) * | 2019-11-04 | 2023-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Azapodophyllotoxin derivatives and methods of treating lymphoma and kidney cancer |
| CN114989180B (zh) * | 2022-05-26 | 2024-06-04 | 广东海洋大学 | 杨叶肖槿内生真菌来源的化合物及其制备方法与应用 |
| US11731980B1 (en) | 2023-03-22 | 2023-08-22 | King Faisal University | Furo[3,4-b]quinolone compounds as antibacterial agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2310746A1 (de) * | 1973-03-03 | 1974-09-12 | Bayer Ag | Verfahren zur herstellung von neuen 1,4-dihydrochinolinen sowie ihre verwendung als arzneimittel |
| IT1228293B (it) * | 1989-02-06 | 1991-06-07 | Angeli Inst Spa | Benzoderivati di composti eterociclici contenenti azoto. |
| NO179904C (no) * | 1992-09-04 | 1997-01-08 | Takeda Chemical Industries Ltd | Kondenserte heterocykliske forbindelser og deres anvendelse |
| DE69422450T2 (de) * | 1993-06-29 | 2000-06-08 | Takeda Chemical Industries, Ltd. | Chinoline oder Chinazolin-Derivate und deren Verwendung zur Herstellung eines Medikaments für die Behandlung von Osteoporose |
| WO1999008528A1 (en) * | 1997-08-19 | 1999-02-25 | Emory University | Noscapine derivatives, useful as anticancer agents |
-
1999
- 1999-11-24 FR FR9914771A patent/FR2801310B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-15 MX MXPA00011240A patent/MXPA00011240A/es active IP Right Grant
- 2000-11-22 SI SI200030061T patent/SI1103554T1/xx unknown
- 2000-11-22 JP JP2000355438A patent/JP3566649B2/ja not_active Expired - Fee Related
- 2000-11-22 AT AT00403255T patent/ATE234305T1/de not_active IP Right Cessation
- 2000-11-22 US US09/718,917 patent/US6548515B1/en not_active Expired - Fee Related
- 2000-11-22 ES ES00403255T patent/ES2194692T3/es not_active Expired - Lifetime
- 2000-11-22 EP EP00403255A patent/EP1103554B9/de not_active Expired - Lifetime
- 2000-11-22 DK DK00403255T patent/DK1103554T5/da active
- 2000-11-22 DE DE60001622T patent/DE60001622T2/de not_active Expired - Fee Related
- 2000-11-23 EA EA200001101A patent/EA003996B1/ru not_active IP Right Cessation
- 2000-11-23 HU HU0004704A patent/HUP0004704A3/hu unknown
- 2000-11-23 NZ NZ508390A patent/NZ508390A/xx unknown
- 2000-11-23 NO NO20005922A patent/NO20005922L/no not_active Application Discontinuation
- 2000-11-24 CN CNB001283189A patent/CN1157394C/zh not_active Expired - Fee Related
- 2000-11-24 AU AU71825/00A patent/AU781300B2/en not_active Ceased
- 2000-11-24 PL PL00344100A patent/PL344100A1/xx not_active Application Discontinuation
- 2000-11-24 CA CA002326710A patent/CA2326710C/fr not_active Expired - Fee Related
- 2000-11-24 ZA ZA200006912A patent/ZA200006912B/xx unknown
- 2000-11-24 KR KR10-2000-0070290A patent/KR100433705B1/ko not_active Expired - Fee Related
- 2000-11-24 BR BR0005557-3A patent/BR0005557A/pt not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |