DK393486D0 - Dihydropyridin-derivater og fremgangsmaade til fremstilling deraf - Google Patents
Dihydropyridin-derivater og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK393486D0 DK393486D0 DK393486A DK393486A DK393486D0 DK 393486 D0 DK393486 D0 DK 393486D0 DK 393486 A DK393486 A DK 393486A DK 393486 A DK393486 A DK 393486A DK 393486 D0 DK393486 D0 DK 393486D0
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- halo
- alkyl
- alk
- nitro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/768,071 US4659717A (en) | 1985-08-21 | 1985-08-21 | Dihydropyridines useful in the treatment of angina and stroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK393486D0 true DK393486D0 (da) | 1986-08-19 |
| DK393486A DK393486A (da) | 1987-02-22 |
Family
ID=25081437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK393486A DK393486A (da) | 1985-08-21 | 1986-08-19 | Dihydropyridin-derivater og fremgangsmaade til fremstilling deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4659717A (da) |
| EP (1) | EP0217530B1 (da) |
| JP (1) | JPS6245586A (da) |
| KR (1) | KR870000904B1 (da) |
| CN (1) | CN86106294A (da) |
| AT (1) | ATE57930T1 (da) |
| AU (1) | AU6158486A (da) |
| CA (1) | CA1265795A (da) |
| DE (1) | DE3675316D1 (da) |
| DK (1) | DK393486A (da) |
| ES (1) | ES2001105A6 (da) |
| GR (1) | GR862150B (da) |
| HU (1) | HU195653B (da) |
| IL (1) | IL79764A0 (da) |
| PT (1) | PT83218A (da) |
| ZA (1) | ZA866222B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902694A (en) * | 1988-08-11 | 1990-02-20 | Eli Lilly And Company | Dihydropyridine calcium channel modulators |
| DE4011106A1 (de) * | 1990-04-06 | 1991-10-10 | Bayer Ag | Neue heterocyclisch substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US5580871A (en) * | 1992-11-20 | 1996-12-03 | The Dupont Merck Pharmaceutical Company | 4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha1 -antagonist activity |
| DE4321030A1 (de) * | 1993-06-24 | 1995-01-05 | Bayer Ag | 4-bicyclisch substituierte Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimittel |
| DE69418789T2 (de) * | 1993-08-05 | 1999-12-02 | Hoechst Marion Roussel, Inc. | 2-(Piperidin-4-yl, Pyridin-4-yl und Tetrahydropyridin-4-yl)-benzofuran-7-carbamat Derivate, ihre Herstellung und Verwendung als Acetylcholinesterase Inhibitoren |
| EP2311806A3 (en) * | 1996-01-29 | 2011-08-10 | The United States of America, Represented by the Secretary, Department of Health and Human Services | Dihydropyridine-, pyridine-, benzopyranone- and triazoloquinazoline derivatives, their preparation and their use as adenosine receptor antagonists |
| US6316423B1 (en) | 1996-04-10 | 2001-11-13 | The United States Of America As Represented By The Departmant Of Health And Human Services | Method of treating ischemic, hypoxic and anoxic brain damage |
| JP3791725B2 (ja) | 1997-09-26 | 2006-06-28 | 旭精工株式会社 | 円板体放出装置 |
| US6376521B1 (en) | 1998-07-10 | 2002-04-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | A3 adenosine receptor antagonists |
| AU2001230913B2 (en) | 2000-01-14 | 2005-06-30 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methanocarba cycloalkyl nucleoside analogues |
| WO2001087878A1 (fr) * | 2000-05-18 | 2001-11-22 | Daiichi Pharmaceutical Co., Ltd. | Nouveaux dérivés de benzothiophène |
| JP5571800B2 (ja) | 2009-11-18 | 2014-08-13 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | フロピリジニル置換１，４−ジヒドロピリジン誘導体およびその使用方法 |
| EP2507241A1 (en) | 2009-12-02 | 2012-10-10 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Methanocarba adenosine derivatives and dendrimer conjugates thereof |
| EP3480201A1 (en) * | 2017-11-06 | 2019-05-08 | Oncostellae, S.L. | New analogs as androgen receptor and glucocorticoid receptor modulators |
| AR117472A1 (es) | 2018-12-21 | 2021-08-11 | Celgene Corp | Inhibidores de tienopiridina de ripk2 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2421899A1 (fr) * | 1978-01-16 | 1979-11-02 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits |
| US4307103A (en) * | 1978-09-08 | 1981-12-22 | Fujisawa Pharmaceutical Co., Ltd. | Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same |
| GB2056435A (en) * | 1979-06-26 | 1981-03-18 | Ciba Geigy Ag | Novel Tetrahydropyridine and Piperidine Substituted Benzofuranes and Related Compounds |
| US4258042A (en) * | 1980-04-11 | 1981-03-24 | Usv Pharmaceutical Corporation | Antihypertensive pyridines and compositions |
| DE3022030A1 (de) * | 1980-06-12 | 1981-12-17 | Bayer Ag, 5090 Leverkusen | 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel |
| GR75101B (da) * | 1980-10-23 | 1984-07-13 | Pfizer | |
| US4442112A (en) * | 1981-09-02 | 1984-04-10 | Sandoz Ltd. | Dihydropyridine derivatives useful in treating vascular headaches |
| DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
| DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE3209276A1 (de) * | 1982-03-13 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung |
| US4500528A (en) * | 1983-03-03 | 1985-02-19 | Usv Pharmaceutical Corporation | N-Substituted 1,4-dihydropyridines and pharmaceutical compositions |
| US4500532A (en) * | 1983-03-03 | 1985-02-19 | Usv Pharmaceutical Corporation | 1-(Substituted aminoalkyl)-1,4-dihydropyridines |
| US4472584A (en) * | 1983-03-03 | 1984-09-18 | Usv Pharmaceutical Corporation | N-Substituted-1-aminoalkyl-1,4-dihydropyridines |
| CH663616A5 (de) * | 1983-06-21 | 1987-12-31 | Sandoz Ag | 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen. |
| US4503223A (en) * | 1983-08-11 | 1985-03-05 | Usv Pharmaceutical Corporation | Process for the purification of N-morpholinoalkyl dihydropyridines |
| FR2567884B1 (fr) * | 1984-07-19 | 1987-03-06 | Roussel Uclaf | Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant |
-
1985
- 1985-08-21 US US06/768,071 patent/US4659717A/en not_active Expired - Fee Related
-
1986
- 1986-08-18 ZA ZA866222A patent/ZA866222B/xx unknown
- 1986-08-18 CA CA000516145A patent/CA1265795A/en not_active Expired - Lifetime
- 1986-08-18 GR GR862150A patent/GR862150B/el unknown
- 1986-08-18 IL IL79764A patent/IL79764A0/xx unknown
- 1986-08-19 PT PT83218A patent/PT83218A/pt unknown
- 1986-08-19 AU AU61584/86A patent/AU6158486A/en not_active Abandoned
- 1986-08-19 HU HU863635A patent/HU195653B/hu unknown
- 1986-08-19 DK DK393486A patent/DK393486A/da not_active Application Discontinuation
- 1986-08-20 DE DE8686306453T patent/DE3675316D1/de not_active Expired - Lifetime
- 1986-08-20 AT AT86306453T patent/ATE57930T1/de not_active IP Right Cessation
- 1986-08-20 JP JP61196484A patent/JPS6245586A/ja active Pending
- 1986-08-20 CN CN198686106294A patent/CN86106294A/zh active Pending
- 1986-08-20 ES ES8601218A patent/ES2001105A6/es not_active Expired
- 1986-08-20 EP EP86306453A patent/EP0217530B1/en not_active Expired - Lifetime
- 1986-08-20 KR KR1019860006866A patent/KR870000904B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK393486A (da) | 1987-02-22 |
| US4659717A (en) | 1987-04-21 |
| KR870000904B1 (ko) | 1987-05-04 |
| PT83218A (en) | 1986-09-01 |
| ATE57930T1 (de) | 1990-11-15 |
| DE3675316D1 (en) | 1990-12-06 |
| HUT44538A (en) | 1988-03-28 |
| KR870002121A (ko) | 1987-03-30 |
| EP0217530B1 (en) | 1990-10-31 |
| IL79764A0 (en) | 1986-11-30 |
| JPS6245586A (ja) | 1987-02-27 |
| CN86106294A (zh) | 1987-02-25 |
| CA1265795A (en) | 1990-02-13 |
| ES2001105A6 (es) | 1988-04-16 |
| HU195653B (en) | 1988-06-28 |
| AU6158486A (en) | 1987-02-26 |
| ZA866222B (en) | 1988-04-27 |
| GR862150B (en) | 1986-12-23 |
| EP0217530A1 (en) | 1987-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |